Folisurge 150 Injection: A Comprehensive Guide to Recombinant FSH
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain or bloating
- Rapid weight gain over 1-2 days
- Difficulty breathing or shortness of breath
- Decreased urine output
- Severe headache with visual disturbances
- Swelling of face, lips, or throat
- Chest pain or leg swelling
If experiencing severe symptoms, call emergency services immediately.
What is nugon 150iu injection used for?
This medicine is a recombinant follicle stimulating hormone used to treat infertility by stimulating egg production in women and sperm production in men. It is administered by injection under medical supervision.
- Generic Name: Recombinant follicle stimulating hormone (150IU)
- Manufacturer: Abbott
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nugon 150iu injection के बारे में (Hindi Summary)
उपयोग: यह दवा रीकॉम्बिनेंट फॉलिकल स्टिमुलेटिंग हार्मोन (150 आईयू) का एक शुद्ध रूप है, जिसका उपयोग बांझपन के इलाज में किया जाता है। यह महिलाओं में अंडाशय को उत्तेजित करके कई अंडे बनाने में मदद करती है, जिससे आईवीएफ और आईसीएसआई जैसी सहायक प्रजनन तकनीकों में सफलता की संभावना बढ़ती है। पुरुषों में, यह शुक्राणु उत्पादन को बढ़ाने के लिए दिया जाता है जब हार्मोन की कमी हो। यह दवा केवल प्रजनन विशेषज्ञ के निर्देशन में ही दी जाती है और इसे स्वयं नहीं लगाना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, लालिमा और सूजन, सिरदर्द, पेट में हल्की परेशानी और मूड में बदलाव शामिल हैं। गंभीर दुष्प्रभावों में ओवेरियन हाइपरस्टिमुलेशन सिंड्रोम (ओएचएसएस) हो सकता है, जिसमें पेट में तेज दर्द, सूजन, तेजी से वजन बढ़ना और सांस लेने में कठिनाई हो सकती है। इसके अलावा, ओवेरियन टॉर्शन, एक्टोपिक प्रेग्नेंसी और मल्टीपल प्रेग्नेंसी के जोखिम भी हो सकते हैं। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। स्वयं इंजेक्शन न लगाएं। अपने प्रजनन विशेषज्ञ के निर्देशों का सख्ती से पालन करें। उपचार के दौरान अल्ट्रासाउंड और रक्त परीक्षण से नियमित निगरानी आवश्यक है। गंभीर पेट दर्द, सूजन, तेजी से वजन बढ़ना या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से संपर्क करें। धूम्रपान और शराब से बचें। यदि आप गर्भवती हैं या हो सकती हैं तो डॉक्टर को बताएं। दवा को 2-8°C पर रेफ्रिजरेट करें और जमने न दें।
💊 nugon 150iu injection Uses & Benefits
[{"condition":"Ovulation induction in women with polycystic ovary syndrome (PCOS)","description":"Used to stimulate the development of a single follicle in women who do not ovulate regularly.","evidence":"Well-established"},{"condition":"Controlled ovarian hyperstimulation for assisted reproductive technologies (ART)","description":"Used to stimulate multiple follicles for IVF, ICSI, and other fertility procedures.","evidence":"Well-established"},{"condition":"Hypogonadotropic hypogonadism in men","description":"Used to stimulate spermatogenesis in men with low gonadotropin levels.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Male infertility with normal gonadotropin levels","description":"Sometimes used off-label to improve sperm parameters in men with idiopathic infertility.","evidence":"Limited"}]
Primary treatment for: Infertility
Also treats: Polycystic ovary syndrome (PCOS), Hypogonadotropic hypogonadism
📋 Drug Information
| Generic Name(s) | Recombinant follicle stimulating hormone (150IU) |
| Brand Name | nugon 150iu injection |
| Manufacturer | Abbott |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Gonadotropins |
| Route of Administration | Parenteral (subcutaneous or intramuscular injection) |
| Storage | Store refrigerated at 2-8°C. Do not freeze. Keep the container in the outer carton to protect from light. Once reconstituted, use immediately or store as directed by the manufacturer. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine acts by binding to follicle stimulating hormone receptors located on the surface of granulosa cells in the ovaries and Sertoli cells in the testes. This binding activates the receptor, which is a G protein-coupled receptor, leading to the activation of adenylyl cyclase and an increase in cyclic AMP levels. The elevated cyclic AMP triggers a cascade of intracellular events that promote cell proliferation, differentiation, and steroidogenesis. In women, this results in follicular growth and maturation, and an increase in estrogen production. In men, it stimulates spermatogenesis by promoting the function of Sertoli cells.
Mechanism Steps
💡 How to Take nugon 150iu injection
Strength: Injection: 150 IU per vial or prefilled pen.
Dosage Information
| Adult Dosage | The dose of this medicine is individualized based on the patient's ovarian response, age, weight, and indication. For ovulation induction, a typical starting dose is 75-150 IU per day, administered subcutaneously or intramuscularly. For controlled ovarian hyperstimulation in IVF, doses may range from 150-300 IU per day. Dose adjustments are made based on ultrasound monitoring of follicular growth and serum estradiol levels. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | This medicine is not intended for use in elderly patients. Safety and efficacy have not been established in this population. |
| Renal Impairment | No specific dose adjustment is provided in the labeling. Use with caution in patients with renal impairment. Consult your doctor for individualized dosing. |
| Hepatic Impairment | No specific dose adjustment is provided in the labeling. Use with caution in patients with hepatic impairment. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose is determined by the treating clinician based on individual response. Doses above 450 IU per day are not recommended. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nugon 150iu injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| GnRH antagonists | Major | |
| GnRH agonists | Major | |
| Clomiphene citrate | Moderate |
🚨 Major Interactions
- Gonadotropin-releasing hormone (GnRH) antagonists
- Gonadotropin-releasing hormone (GnRH) agonists
⚡ Moderate Interactions
- Clomiphene citrate
🍷 Alcohol Interaction
Alcohol consumption may reduce fertility and should be avoided during treatment with this medicine. It can also worsen side effects such as mood swings and abdominal discomfort.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to follicle stimulating hormone or any excipient","Ovarian cysts or enlarged ovaries not due to polycystic ovary syndrome","Abnormal uterine bleeding of unknown origin","Hormone-sensitive tumors of the reproductive system","Primary ovarian failure","Pregnancy and breastfeeding"]
⚠️ Warnings & Precautions
["This medicine should only be prescribed by a fertility specialist.","Ovarian hyperstimulation syndrome (OHSS) can occur; monitor closely.","Multiple pregnancies are a risk; discuss with your doctor.","Ectopic pregnancy risk is increased in women with tubal disease.","Thromboembolic events have been reported; use with caution in women with risk factors.","Injection site reactions may occur; rotate sites.","Do not use if the solution is discolored or contains particles."]
🤱 Lactation Safety
It is not known whether this medicine is excreted in human breast milk. It is not recommended for use during breastfeeding. Consult your doctor before using this medicine if you are breastfeeding.
💊 Overdose Management
Overdose may lead to ovarian hyperstimulation syndrome. If overdose is suspected, seek immediate medical attention. Treatment is symptomatic and supportive, including monitoring of ovarian size and fluid balance. In severe cases, hospitalization may be required.
⏰ Missed Dose
If you miss a dose, contact your fertility specialist for guidance. Do not double the dose to make up for a missed one. The timing of doses is critical for treatment success, so follow your doctor's instructions carefully.
Additional Safety Advice
This medicine must only be administered by a healthcare professional. Do not self-inject. Follow your fertility specialist's instructions exactly regarding dose and timing. Regular monitoring with ultrasound and blood tests is mandatory to assess ovarian response and adjust the dose. Report any severe abdominal pain, bloating, rapid weight gain, or difficulty breathing immediately, as these may be signs of ovarian hyperstimulation syndrome. Avoid alcohol and smoking during treatment as they can reduce fertility. Inform your doctor if you are pregnant or suspect you might be pregnant before starting this medicine. Use effective contraception during treatment unless you are undergoing fertility treatment. Store this medicine as directed, typically refrigerated at 2-8°C, and do not freeze. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
This medicine is not intended for use in elderly patients. Safety and efficacy have not been established in this population.
🤰 Pregnancy Planning (TTC)
This medicine is used to help achieve pregnancy. If you are planning pregnancy, consult your fertility specialist for a comprehensive evaluation and personalized treatment plan. Once pregnancy is confirmed, discontinue this medicine and follow your obstetrician's advice.
🏥 Post-Surgery Considerations
If you have undergone recent surgery, inform your fertility specialist before starting this medicine. Depending on the type of surgery, your doctor may recommend delaying treatment.
🦷 Dental Procedures
There are no specific precautions for dental procedures while on this medicine. However, inform your dentist about your treatment and any medications you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe during treatment, but avoid high-impact activities that may cause ovarian torsion, especially if you have enlarged ovaries. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause mild fatigue or mood swings, which could affect your daily activities. However, most patients can continue their normal routines. If you experience dizziness or severe abdominal discomfort, avoid driving or operating heavy machinery.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your fertility specialist. Treatment duration is determined by your response and the specific protocol. If you experience severe side effects, contact your doctor immediately for guidance.
📅 Long-Term Use Effects
Long-term use of this medicine is generally limited to the duration of fertility treatment cycles. There is no evidence of long-term harm when used as prescribed. However, women who undergo multiple cycles of ovarian stimulation may have a slightly increased risk of ovarian tumors, though studies are inconclusive. Regular follow-up with your specialist is recommended.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
An oral medication for ovulation induction, often used as a first-line treatment.
Evidence: Well-establishedAn oral aromatase inhibitor used for ovulation induction, particularly in PCOS.
Evidence: Well-establishedA procedure that can be combined with ovulation induction for certain infertility cases.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, it is advisable to be up to date on routine vaccinations before starting fertility treatment. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store refrigerated at 2-8°C
❌ DON'T
Do not freeze
✅ DO
Keep in original carton to protect from light
❌ DON'T
Do not expose to direct sunlight
✅ DO
Use immediately after reconstitution
❌ DON'T
Do not store reconstituted solution for long periods
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with a copy of your prescription. Keep it refrigerated using a cooler bag with ice packs, but avoid direct contact with ice. Inform airport security about the medication and any needles. Check the laws of your destination country regarding carrying prescription medications. If crossing time zones, consult your doctor about adjusting the timing of your injections.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Follicular growth usually begins within 5-7 days, but the full effect takes about 10-14 days. Your doctor will monitor your response with ultrasound.
A: Yes, after proper training from your healthcare provider, you may be able to self-administer the injection. Always follow aseptic technique.
A: Signs include severe abdominal pain, bloating, rapid weight gain, nausea, vomiting, and difficulty breathing. Seek immediate medical attention if these occur.
🤔 Common Patient Concerns
🔄 Substitutes for nugon 150iu injection
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Follokon 150IU InjectionBiosena Lifescience ₹1,171.88 0.9% CHEAPER
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gonotrop f 150iu injectionWin Medicare Pvt Ltd ₹1,445.00 22.1% COSTLIER
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xyartz hp fsh 150iu injectionXyata Life Sciences Pvt Ltd ₹1,593.75 34.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine guarantees pregnancy.
Fact: It improves the chances of pregnancy but does not guarantee success. Many factors affect fertility outcomes. - Myth: This medicine is safe for everyone.
Fact: It is contraindicated in certain conditions and must be prescribed by a specialist. - Myth: This medicine can be taken without monitoring.
Fact: Regular monitoring with ultrasound and blood tests is essential to prevent complications.
🔄 Alternative Options
Generic Alternatives
- Recombinant follicle stimulating hormone
Brand Alternatives
- Folisurge 150 Injection