augxetil 500mg tablet - Uses, Price, Side Effects & Substitutes
What is augxetil 500mg tablet used for?
Altacef 500 Tablet (Cefuroxime) is used to treat Upper and lower respiratory tract infections. It contains Cefuroxime (500mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.
- Generic Name: Cefuroxime
- Manufacturer: Koye Pharmaceuticals Pvt ltd
- Medicine Form: Allopathy
- Pregnancy Category: B
🇮🇳 augxetil 500mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
augxetil 500mg tablet का उपयोग मुख्य रूप से anti infectives और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Cefuroxime (500mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Cefuroxime |
|---|---|
| Brand Name | Altacef 500 Tablet |
| Manufacturer | Koye Pharmaceuticals Pvt ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 2nd generation |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C); protect from light and moisture. |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take augxetil 500mg tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at room temperature (20-25°C); protect from light and moisture.
⚙️ How augxetil 500mg tablet Works
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidase and autolysin activity.
💊 augxetil 500mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Upper and lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, otitis media, sinusitis, gonorrhea, Lyme disease.
Off-label uses: Prophylaxis for surgical infections, treatment of bone and joint infections.
⚠️ What are the side effects of augxetil 500mg tablet?
✅ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Rash
- Injection site reactions (if IV)
🚨 Serious Side Effects
- Severe allergic reactions (anaphylaxis)
- Clostridioides difficile diarrhea
- Seizures (high doses)
- Stevens-Johnson syndrome
⚠️ Rare Side Effects
- Hemolytic anemia
- Interstitial nephritis
- Hepatitis
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Probenecid | Major | Decreased renal excretion of cefuroxime, increased levels |
| Live typhoid vaccine | Major | Reduced vaccine efficacy |
| BCG vaccine | Major | Reduced vaccine efficacy |
| Loop diuretics | Moderate | Increased nephrotoxicity risk |
| Aminoglycosides | Moderate | Increased nephrotoxicity risk |
| Oral contraceptives | Moderate | Reduced contraceptive efficacy |
| Antacids | Minor | Decreased absorption of cefuroxime |
| H2 antagonists | Minor | Decreased absorption of cefuroxime |
| Proton pump inhibitors | Minor | Decreased absorption of cefuroxime |
🚨 Major Interactions
- Warfarin
- Probenecid
- Live typhoid vaccine
- BCG vaccine
⚡ Moderate Interactions
- Loop diuretics
- Aminoglycosides
- Oral contraceptives
- BCG (intravesical)
ℹ️ Minor Interactions
- Antacids
- H2 antagonists
- Proton pump inhibitors
🍽️ Food Interactions
Food increases absorption; take with food.
🍷 Alcohol Interaction
No known interaction; but may increase risk of disulfiram-like reaction (rare).
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to cefuroxime or other cephalosporins; previous immediate hypersensitivity reaction to penicillins.
📊 Monitoring Parameters
Renal function, signs of hypersensitivity, superinfection, bleeding (if on warfarin).
🤱 Lactation Safety
Excreted in breast milk in small amounts; generally considered compatible with breastfeeding.
💊 Overdose Management
Supportive care; hemodialysis may enhance elimination.
⏰ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose and resume regular schedule. Do not double dose.
🛑 Myths vs. Facts about augxetil 500mg tablet
- Myth: Generic substitutes of augxetil 500mg tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Cefuroxime (500mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of augxetil 500mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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