clopram 25mg tablet - Metoclopramide (25mg) medicine

clopram 25mg tablet

4.5 (10 reviews)
๐Ÿญ Mayflower India ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is clopram 25mg tablet used for?

Bacnorm 5mg Oral Drops (Metoclopramide) is used to treat GASTRO INTESTINAL. It contains Metoclopramide (25mg), which Blocks dopamine D2 receptors in the chemoreceptor trigger zone (CTZ) and enhance. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Metoclopramide
  • Manufacturer: Mayflower India
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š clopram 25mg tablet Uses & Benefits

Nausea and vomiting (including chemotherapy-induced), gastroparesis, gastroesophageal reflux disease (GERD).

Off-label uses: Migraine-associated nausea, postoperative nausea, hiccups.

๐Ÿ“‹ Drug Information

Generic Name(s)Metoclopramide
Brand NameBacnorm 5mg Oral Drops
ManufacturerMayflower India
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassDopamine (D2) receptor antagonist-Prokinetic agent
Route of AdministrationOral (drops).
StorageStore at room temperature (20-25ยฐC), protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the gastrointestinal tract.
DistributionWidely distributed in body tissues; crosses blood-brain barrier and placenta.
Protein BindingApproximately 30% bound to plasma proteins.
MetabolismHepatic metabolism via CYP2D6 and other pathways.
Half-Life4-6 hours (normal renal function); prolonged in renal impairment.
ExcretionPrimarily renal (about 85% as unchanged drug and metabolites).
Bioavailability80-100% (oral).
Onset of Action30-60 minutes (oral).
Peak Plasma Time1-2 hours (oral).
Duration of Action1-2 hours (single dose).

How It Works

Blocks dopamine D2 receptors in the chemoreceptor trigger zone (CTZ) and enhances gastric motility via cholinergic pathways.

Mechanism Steps

1Blocks dopamine D2 receptors in the chemoreceptor trigger zone (CTZ) of the medulla oblongata.
2Increases lower esophageal sphincter tone and gastric motility via cholinergic pathways.
3At high doses, also blocks 5-HT3 receptors in the CTZ and gastrointestinal tract.

๐Ÿ’ก How to Take clopram 25mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of clopram 25mg tablet

โœ… Common Side Effects

  • Drowsiness
  • Fatigue
  • Restlessness
  • Diarrhea
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Tardive dyskinesia
  • Neuroleptic malignant syndrome
  • QT prolongation
  • Seizures

โš ๏ธ Rare Side Effects

  • Agranulocytosis
  • Hepatotoxicity
  • Hypersensitivity reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Antipsychotics Major Increased risk of extrapyramidal symptoms
MAOIs Major Hypertensive crisis
Serotonergic drugs Major Serotonin syndrome
CNS depressants Major Enhanced sedation
Anticholinergics Moderate Reduced prokinetic effect
Opioid analgesics Moderate Increased CNS depression
Digoxin Moderate Reduced digoxin absorption
Cyclosporine Moderate Increased cyclosporine absorption
Acetaminophen Minor Increased absorption of acetaminophen
Levodopa Minor Reduced levodopa absorption
Lithium Minor Increased lithium absorption

๐Ÿšจ Major Interactions

  • Antipsychotics
  • MAOIs
  • Serotonergic drugs
  • CNS depressants

โšก Moderate Interactions

  • Anticholinergics
  • Opioid analgesics
  • Digoxin
  • Cyclosporine

โ„น๏ธ Minor Interactions

  • Acetaminophen
  • Levodopa
  • Lithium

๐Ÿฝ๏ธ Food Interactions

None significant

๐Ÿท Alcohol Interaction

Increased CNS depression; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

GI obstruction, perforation, hemorrhage; pheochromocytoma; history of tardive dyskinesia; epilepsy; concurrent use with drugs causing extrapyramidal reactions.

๐Ÿ“Š Monitoring Parameters

Renal function, liver function, extrapyramidal symptoms, sedation.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; caution advised.

๐Ÿ’Š Overdose Management

Supportive care; benzodiazepines for extrapyramidal symptoms; physostigmine for anticholinergic effects.

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

โญ User Reviews

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory