codep 37 tablet
What is codep 37 tablet used for?
Codep 37 Tablet (Chlordiazepoxide + Imipramine) is used to treat NEURO CNS. It contains Chlordiazepoxide (NA) + Imipramine (NA), which Chlordiazepoxide enhances GABA activity; Imipramine inhibits reuptake of norepin. Always consult your doctor before use. Take as prescribed.
- Generic Name: Chlordiazepoxide + Imipramine
- Manufacturer: Mayflower India
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ codep 37 tablet Uses & Benefits
Anxiety with depression, panic disorder, mixed anxiety-depressive disorder
Off-label uses: Chronic pain, insomnia, irritable bowel syndrome
๐ Drug Information
| Generic Name(s) | Chlordiazepoxide + Imipramine |
| Brand Name | Codep 37 Tablet |
| Manufacturer | Mayflower India |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Benzodiazepine + Tricyclic Antidepressant |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC, protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Chlordiazepoxide enhances GABA activity; Imipramine inhibits reuptake of norepinephrine and serotonin.
Mechanism Steps
๐ก How to Take codep 37 tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of codep 37 tablet
โ Common Side Effects
- Drowsiness
- Dry mouth
- Constipation
- Blurred vision
- Dizziness
๐จ Serious Side Effects
- Arrhythmias
- Seizures
- Serotonin syndrome
- Suicidal ideation
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Hepatotoxicity
- Paradoxical reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Hypertensive crisis, serotonin syndrome |
| CNS depressants | Major | Increased sedation and respiratory depression |
| Anticholinergics | Major | Additive anticholinergic effects |
| QT-prolonging agents | Major | Increased risk of arrhythmias |
| CYP450 inducers | Moderate | Reduced efficacy |
| CYP450 inhibitors | Moderate | Increased toxicity |
| Antihypertensives | Moderate | Additive hypotensive effect |
| Anticoagulants | Moderate | Altered anticoagulant effect |
| Cimetidine | Minor | Increased imipramine levels |
| Oral contraceptives | Minor | Reduced imipramine clearance |
๐จ Major Interactions
- MAOIs
- CNS depressants
- Anticholinergics
- QT-prolonging agents
โก Moderate Interactions
- CYP450 inducers/inhibitors
- Antihypertensives
- Anticoagulants
โน๏ธ Minor Interactions
- Cimetidine
- Oral contraceptives
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase levels
๐ท Alcohol Interaction
Enhanced CNS depression; avoid alcohol
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, recent MI, narrow-angle glaucoma, urinary retention, MAOI use within 14 days
๐ Monitoring Parameters
Liver function, ECG, blood pressure, mental status
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Supportive care, activated charcoal, flumazenil for chlordiazepoxide, sodium bicarbonate for imipramine cardiotoxicity
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip if close to next dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Helpful and effective medicine as per my experience. Always consult a doctor.
Effective and reliable. Worked as expected.
Found this to be a helpful product. Good results.
This medicine was effective for me. I followed the doctor's advice.