cisar 10mg tablet - Cisapride (10mg) medicine

cisar 10mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Hamax Pharmaceuticals ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is cisar 10mg tablet used for?

Alipride (Cisapride) is used to treat GASTRO INTESTINAL. It contains Cisapride (10mg), which Enhances release of acetylcholine in the myenteric plexus, increasing gastrointe. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cisapride
  • Manufacturer: Hamax Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š cisar 10mg tablet Uses & Benefits

Gastroesophageal reflux disease (GERD), gastroparesis, chronic constipation, and other motility disorders.

Off-label uses: Diabetic gastroparesis, intestinal pseudo-obstruction.

๐Ÿ“‹ Drug Information

Generic Name(s)Cisapride
Brand NameAlipride
ManufacturerHamax Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassSerotonin (5-HT4) receptor agonist-Prokinetic agent
Route of AdministrationOral.
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentration achieved within 1-2 hours.
DistributionWidely distributed in body tissues; crosses the blood-brain barrier minimally.
Protein BindingApproximately 98% bound to plasma proteins, mainly albumin.
MetabolismExtensively metabolized in the liver via CYP3A4; major metabolites include norcisapride.
Half-Life6-12 hours; prolonged in hepatic impairment.
ExcretionPrimarily excreted in urine (40-50% as metabolites) and feces (30-40%).
Bioavailability40-50% due to first-pass metabolism.
Onset of Action30-60 minutes after oral administration.
Peak Plasma Time1-2 hours.
Duration of Action8-12 hours.

How It Works

Enhances release of acetylcholine in the myenteric plexus, increasing gastrointestinal motility.

Mechanism Steps

1Binds to 5-HT4 receptors on enteric neurons
2Stimulates release of acetylcholine from presynaptic terminals
3Acetylcholine activates muscarinic receptors on smooth muscle

๐Ÿ’ก How to Take cisar 10mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cisar 10mg tablet

โœ… Common Side Effects

  • Headache
  • Diarrhea
  • Abdominal pain
  • Nausea
  • Flatulence

๐Ÿšจ Serious Side Effects

  • QT prolongation
  • Torsades de pointes
  • Cardiac arrest
  • Seizures

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Extrapyramidal symptoms
  • Hypersensitivity reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Ketoconazole Major Increased risk of cardiac arrhythmias (QT prolongation)
Erythromycin Major Increased risk of cardiac arrhythmias (QT prolongation)
Grapefruit juice Moderate Increased cisapride plasma concentration

๐Ÿšจ Major Interactions

  • Ketoconazole
  • Itraconazole
  • Erythromycin
  • Clarithromycin
  • Fluconazole
  • Ritonavir
  • Nefazodone

โšก Moderate Interactions

  • Cimetidine
  • Ranitidine
  • Grapefruit juice
  • Verapamil
  • Diltiazem

โ„น๏ธ Minor Interactions

  • Antacids
  • Sucralfate
  • Digoxin

๐Ÿฝ๏ธ Food Interactions

Grapefruit juice increases bioavailability; high-fat meals may delay absorption.

๐Ÿท Alcohol Interaction

Alcohol may enhance sedative effects; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Known hypersensitivity, history of QT prolongation, concurrent use of CYP3A4 inhibitors, electrolyte disturbances, severe hepatic impairment.

๐Ÿ“Š Monitoring Parameters

ECG for QT interval, electrolytes (K+, Mg2+), liver function tests.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; avoid use due to potential cardiac effects in infants.

๐Ÿ’Š Overdose Management

Induce emesis or gastric lavage; monitor ECG for QT prolongation; supportive care.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cisar 10mg tablet

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Alternative brands with exact same active ingredient (Cisapride (10mg)):

Medical Note: Always consult your doctor before switching medications.

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