Alipride 10mg Tablet (cisapride): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Racing, pounding, or irregular heartbeat
- Chest pain or tightness
- Fainting or loss of consciousness
- Severe dizziness or light-headedness
- Swelling of the face, lips, tongue, or throat
- Difficulty breathing or wheezing
- Severe abdominal pain with vomiting
- Yellowing of the skin or eyes
- Unusual bruising or bleeding
- Decreased urine output or severe dehydration
If experiencing severe symptoms, call emergency services immediately.
What is cisakem 10mg tablet used for?
This medicine contains cisapride 10 mg, a prokinetic agent that helps the stomach and intestines move food more efficiently. It is used in selected patients for heartburn, bloating, and slow stomach emptying, but it can cause serious heart rhythm problems and is restricted in many countries. It must only be used under close medical supervision.
- Generic Name: Cisapride
- Manufacturer: Alkem Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cisakem 10mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सिसाप्राइड 10 मिलीग्राम की एक टैबलेट है जो मुँह से ली जाती है। यह पेट और आंतों की गति को सुधारने वाली दवा है। इसका उपयोग कुछ चुने हुए रोगियों में सीने में जलन, खट्टी डकार, पेट में भारीपन, जी मिचलाना और पेट के खाली होने में देरी जैसी समस्याओं के लिए किया जाता है। यह दवा पेट की मांसपेशियों को अधिक व्यवस्थित तरीके से सिकोड़ने में मदद करती है, जिससे भोजन जल्दी आगे बढ़ता है। लेकिन यह दवा दिल की धड़कन को प्रभावित कर सकती है, इसलिए इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए। जिन लोगों को दिल की अनियमित धड़कन, कम पोटैशियम या मैग्नीशियम, या गंभीर जिगर की बीमारी है, उन्हें यह दवा नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में सिरदर्द, पेट में दर्द, दस्त, जी मिचलाना और थकान शामिल हैं। कुछ लोगों को दिल की धड़कन तेज या अनियमित महसूस हो सकती है, चक्कर आ सकते हैं या बेहोशी हो सकती है। बहुत कम मामलों में यह दवा दिल की गंभीर अनियमित धड़कन पैदा कर सकती है। अगर आपको सीने में बेचैनी, धड़कन में गड़बड़ी, सांस लेने में कठिनाई, चेहरे या गले में सूजन, या त्वचा पर गंभीर दाने दिखें, तो तुरंत डॉक्टर से मिलें या आपातकालीन सहायता लें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर की सलाह और निगरानी में ही लें। शुरू करने से पहले अपने डॉक्टर को अपनी सभी दवाओं, जड़ी-बूटियों और पूरक आहार के बारे में बताएं, क्योंकि कई दवाएं इसके साथ खतरनाक प्रतिक्रिया कर सकती हैं। डॉक्टर आपका ईसीजी और खून की जांच कर सकते हैं। इस दवा के साथ अंगूर का जूस न पिएं। शराब न पिएं। अपनी मर्जी से दवा की मात्रा न बढ़ाएं और न ही घटाएं। अगर आपको उल्टी या दस्त हो रहे हैं, तो डॉक्टर को बताएं क्योंकि इससे शरीर में पानी और नमक की कमी हो सकती है, जो दिल के लिए खतरनाक है। नियमित फॉलो-अप जरूर करें।
💊 cisakem 10mg tablet Uses & Benefits
[{"condition":"Gastro-oesophageal reflux disease (GERD)","description":"This medicine may be used in selected patients to reduce heartburn and regurgitation by improving the movement of the lower food pipe and speeding up stomach emptying.","evidence":"Limited; use is restricted because of cardiac safety concerns."},{"condition":"Functional dyspepsia","description":"It may help relieve upper abdominal fullness, early satiety, bloating, and nausea in some patients with functional dyspepsia.","evidence":"Limited; benefit is modest and use is restricted."},{"condition":"Gastroparesis","description":"This medicine has been used to improve stomach emptying in people with slow stomach movement, but safer alternatives are usually preferred.","evidence":"Limited; not a first-line option."},{"condition":"Chronic constipation","description":"It may increase bowel movements in some patients, but it is not a standard or preferred treatment for constipation.","evidence":"Limited; safer laxatives are preferred."}]
Off-label uses: [{"condition":"Paediatric feeding intolerance","description":"Cisapride has sometimes been used in newborns and infants with feeding intolerance, but this use is not recommended because of serious heart rhythm risks.","evidence":"Limited and not recommended."},{"condition":"Intestinal pseudo-obstruction","description":"It has occasionally been tried in selected patients with poor intestinal movement, but evidence is weak and safer options exist.","evidence":"Limited."}]
Primary treatment for: Gastro-oesophageal reflux disease and other motility disorders of the upper digestive tract in selected patients.
Also treats: Functional dyspepsia, Gastroparesis, Chronic constipation, Non-ulcer dyspepsia
📋 Drug Information
| Generic Name(s) | Cisapride |
| Brand Name | Alipride |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Serotonin (5-HT4) receptor agonist-Prokinetic agent |
| Route of Administration | Oral. This medicine is taken by mouth as a tablet, usually with a glass of water. It may be taken with or without food, but your doctor will advise you on the best way to take it for your condition |
| Storage | Store this medicine at room temperature, between 15°C and 30°C, in a dry place. Keep it in the original container, tightly closed, and away from direct sunlight and moisture. Do not store it in the bathroom. Keep all medicines out of the reach of children and pets. |
| Shelf Life | The shelf life is usually 24 to 36 months from the date of manufacture, depending on the manufacturer. Always check the expiry date printed on the pack and do not use the medicine after that date. |
| WHO Guideline | Not established from the available information. Cisapride is restricted or withdrawn in many countries because of cardiac safety concerns, and its use is not recommended in current major guidelines. |
| ICMR Guideline | Not established from the available information. Indian guidelines generally do not recommend cisapride because of safety concerns, and safer alternatives are preferred. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by stimulating the movement of the digestive tract. It increases the release of acetylcholine, a natural chemical messenger that helps the muscles of the stomach and intestines contract. It also blocks the action of serotonin at certain receptors, which helps coordinate the pushing movement of the gut. The result is faster stomach emptying and stronger, more organised movement through the small and large intestine. Because it can also affect the electrical signalling of the heart, it must be used with caution and only in selected patients.
Mechanism Steps
💡 How to Take cisakem 10mg tablet
Strength: This medicine is available as an immediate-release tablet containing 10 mg of cisapride.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 mg taken by mouth up to three or four times a day, depending on the condition being treated and the doctor's assessment. Some patients may be started on a lower dose. The dose must be individualised by a qualified clinician based on the indication, age, weight, kidney function, liver function, and other medicines you are taking. Do not change the dose on your own. Take the tablet at the same times each day, with or without food as advised. If you miss a dose, follow the missed dose instructions provided with this medicine. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Cisapride is not recommended for children because of serious heart rhythm risks. |
| Elderly Dosage | Older adults may be more sensitive to the effects of this medicine, especially dizziness, low blood pressure, and heart rhythm changes. The dose must be individualised by a qualified clinician, and heart and kidney function should be checked before and during treatment. Lower doses may be used, and the medicine should be avoided in frail elderly patients with heart disease. |
| Renal Impairment | Cisapride is partly removed by the kidneys. In patients with reduced kidney function, the medicine may accumulate and increase the risk of side effects. The dose must be individualised by a qualified clinician, and kidney function should be monitored. In severe kidney impairment, this medicine is usually avoided. |
| Hepatic Impairment | Cisapride is extensively metabolised by the liver. In patients with liver impairment, the medicine can build up in the body and increase the risk of heart rhythm problems. The dose must be individualised by a qualified clinician, and liver function should be monitored. In severe liver impairment, this medicine is contraindicated. |
| Maximum Daily Dose | The maximum daily dose is not established from the available information and must be determined by a qualified clinician. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cisakem 10mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Clarithromycin | Major | |
| Amiodarone | Major | |
| Haloperidol | Major | |
| Citalopram | Major | |
| Furosemide | Moderate | |
| Cimetidine | Moderate | |
| Grapefruit juice | Moderate | |
| Hyoscine | Minor | |
| Antacids | Minor |
🚨 Major Interactions
- Ketoconazole, itraconazole, clarithromycin, erythromycin, and other strong CYP3A4 inhibitors
- Amiodarone, sotalol, quinidine, procainamide, and other QT-prolonging antiarrhythmics
- Antipsychotics such as haloperidol, thioridazine, and ziprasidone
- Antidepressants such as citalopram, escitalopram, and amitriptyline
- Diuretics that cause potassium loss, such as furosemide and hydrochlorothiazide
⚡ Moderate Interactions
- Grapefruit juice
- Cimetidine
- Anticholinergic medicines such as hyoscine and oxybutynin
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can increase the risk of dizziness, drowsiness, and irregular heartbeat, and it may worsen the underlying digestive symptoms. If you drink alcohol regularly, discuss this with your doctor before starting treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to cisapride or any ingredient of this tablet.","History of QT prolongation, torsades de pointes, or other serious heart rhythm problems.","Congenital long QT syndrome or a family history of sudden cardiac death.","Low blood potassium or magnesium levels that have not been corrected.","Severe heart disease such as recent heart attack, heart failure, or severe angina.","Use of other medicines that prolong the QT interval or strongly inhibit CYP3A4.","Severe liver impairment.","Gastrointestinal obstruction, perforation, or active bleeding.","Pregnancy and breastfeeding, unless specifically advised by a specialist."]
⚠️ Warnings & Precautions
["This medicine can cause serious heart rhythm problems. It must only be used when clearly needed and under close medical supervision.","Tell your doctor about all other medicines you take, including over-the-counter and herbal products, because many can interact dangerously with cisapride.","Avoid grapefruit juice while taking this medicine.","Do not take more than the prescribed dose.","Contact your doctor if you develop vomiting, diarrhoea, or any condition that can cause dehydration, because low electrolyte levels increase the risk of heart rhythm problems.","Do not drive or operate machinery if you feel dizzy, tired, or have palpitations.","Keep all follow-up appointments for ECG and blood tests.","Do not share this medicine with anyone else, even if they have similar symptoms."]
🤱 Lactation Safety
Cisapride passes into breast milk in small amounts. Because of the potential for serious heart rhythm problems in a nursing infant, this medicine is generally not recommended during breastfeeding. Discuss safer alternatives with your doctor.
💊 Overdose Management
Overdose of this medicine can cause severe heart rhythm problems, low blood pressure, and fainting. If you suspect an overdose, seek emergency medical care immediately. Do not try to vomit unless told to do so by a medical professional. Treatment is supportive and may include continuous heart monitoring, correction of electrolyte levels, and medicines to control abnormal heart rhythms. Carry the medicine packaging with you to show the emergency team.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, provided there is still a long time before your next dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, contact your doctor or pharmacist.
Additional Safety Advice
This medicine must only be taken when a qualified clinician has confirmed that it is safe for you. Before starting treatment, tell your doctor about all other medicines you take, including antibiotics, antifungals, antidepressants, antipsychotics, and heart medicines, because many of these can interact dangerously with cisapride. Do not start or stop any other medicine without asking your doctor first. Your doctor may arrange an electrocardiogram and blood tests to check your potassium and magnesium levels before and during treatment. Avoid drinking grapefruit juice while taking this medicine because it can raise the level of the medicine in your body. Do not take more than the prescribed dose and do not share this medicine with anyone else. If you become dehydrated from vomiting or diarrhoea, contact your doctor because low body fluid and electrolyte levels can increase the risk of heart rhythm problems. Keep all follow-up appointments so that your doctor can monitor your response and adjust treatment if needed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are more likely to experience dizziness, low blood pressure, and heart rhythm problems with this medicine. The dose must be individualised by a qualified clinician, and heart, kidney, and liver function should be checked before and during treatment. This medicine is generally avoided in frail elderly patients and in those with any history of heart disease.
🤰 Pregnancy Planning (TTC)
This medicine is generally not recommended if you are pregnant or planning to become pregnant. If you are trying to conceive, discuss safer treatment options with your doctor before starting or continuing this medicine. Do not stop any prescribed medicine without medical advice.
🏥 Post-Surgery Considerations
After surgery, gut movement may be slow, but this medicine is not routinely recommended because of its heart rhythm risks. Your surgical team will choose safer alternatives if needed. Always inform your surgeon and anaesthetist about all medicines you take, including this one, before any operation.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. There is no direct interaction with common dental anaesthetics, but if you have heart rhythm problems or are taking other medicines, your dentist may need to take extra precautions. Do not stop this medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate physical activity is generally safe while taking this medicine, but avoid vigorous exercise immediately after taking a dose if you feel dizzy or tired. If you experience palpitations, chest discomfort, or fainting during exercise, stop immediately and seek medical attention. Discuss your exercise routine with your doctor before starting any new intense programme.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, tiredness, or palpitations in some people. Do not drive or operate heavy machinery until you know how this medicine affects you. If your job involves operating machinery or working at heights, discuss this with your doctor. Most people can continue their normal daily activities, but you should report any new symptoms to your doctor promptly.
🛑 When to Stop This Medicine
Stop this medicine and seek immediate medical attention if you develop palpitations, irregular heartbeat, chest pain, fainting, severe dizziness, swelling of the face or throat, or difficulty breathing. Do not stop this medicine for any other reason without consulting your doctor, because stopping suddenly may not be appropriate for your condition. Your doctor will decide whether to continue, change, or stop the treatment based on your response and any side effects.
📅 Long-Term Use Effects
Long-term use of this medicine is generally not recommended because of the risk of serious heart rhythm problems. If treatment is continued, regular ECG monitoring and blood tests for potassium and magnesium are needed. Your doctor will reassess the benefit and risk at each visit and may switch you to a safer alternative. Long-term use should be avoided in elderly patients and in anyone with heart disease.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Medicines such as pantoprazole and omeprazole reduce stomach acid and are commonly used for reflux symptoms with a better safety profile.
Evidence: Well-establishedMedicines such as ranitidine and famotidine reduce acid production and may help mild reflux symptoms.
Evidence: Well-establishedWeight loss, smaller meals, avoiding late meals, and raising the head of the bed can reduce reflux symptoms.
Evidence: Well-establishedMedicines such as domperidone, metoclopramide, or levosulpiride may be considered as alternatives, depending on the patient's condition and safety profile.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are unwell with a fever or infection, speak to your doctor before receiving any vaccine. Keep your routine vaccinations up to date as advised by your healthcare provider.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specifically instructed
✅ DO
Keep the tablets in the original container with the lid tightly closed
❌ DON'T
Do not transfer the tablets to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of the reach of children and pets
❌ DON'T
Do not use after the expiry date printed on the pack
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label clearly visible. Keep a copy of your prescription and a letter from your doctor explaining why you need this medicine, especially if you are crossing international borders. Store the tablets in a cool, dry place away from direct sunlight and do not leave them in a hot car. If you are crossing time zones, ask your doctor how to adjust the timing of your doses. Carry enough medicine for your entire trip and a little extra in case of delays. Declare the medicine to customs if required and keep it in your hand luggage rather than checked baggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The effect on gut movement usually begins within 30 to 60 minutes after a dose, but it may take several days of regular use before you notice full relief from symptoms such as heartburn and bloating.
A: Yes, this medicine may be taken with or without food. Taking it with a light snack may reduce stomach upset. Avoid grapefruit juice completely.
A: Stop the medicine and seek medical attention immediately. Palpitations, dizziness, or fainting may be signs of a serious heart rhythm problem.
A: This medicine is generally not recommended during pregnancy because of safety concerns. If you are pregnant or planning pregnancy, discuss safer alternatives with your doctor.
A: Do not stop this medicine without talking to your doctor. Your doctor will decide whether to continue, change, or stop the treatment based on your response and any side effects.
🤔 Common Patient Concerns
🔄 Substitutes for cisakem 10mg tablet
View AllAlternative brands with exact same active ingredient:
-
alzide 10mg tabletAlembic Pharmaceuticals Ltd ₹16.25 63.2% COSTLIER
-
cisar 10mg tabletHamax Pharmaceuticals ₹28.00 181.1% COSTLIER
-
expracid 10mg tabletExcare Laboratories ₹28.13 182.4% COSTLIER
-
gastropen 10mg tabletMorepen Laboratories Ltd ₹29.90 200.2% COSTLIER
-
pride 10mg tabletEmerge Pharma Pvt Ltd ₹30.00 201.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a simple antacid and is safe for everyone.
Fact: This medicine is not an antacid. It is a prokinetic agent that can affect the heart rhythm and is only suitable for selected patients under medical supervision. - Myth: You can take this medicine for as long as you like without any tests.
Fact: Regular ECG and blood tests are needed because this medicine can cause serious heart rhythm problems, especially with long-term use. - Myth: If one tablet does not work, taking two will work faster.
Fact: Taking more than the prescribed dose can be dangerous and increases the risk of heart rhythm problems. Never increase the dose on your own. - Myth: This medicine is safe to take with any other medicine.
Fact: Many medicines interact dangerously with cisapride, including certain antibiotics, antifungals, and antidepressants. Always tell your doctor about all medicines you take.
🔄 Alternative Options
Generic Alternatives
- Cisapride 10 mg tablet
Brand Alternatives
- Alipride 10 mg tablet