cherifon syrup - Bromhexine (8mg) + Guaifenesin (50mg) medicine

Cherifon Syrup: Complete Medicine Guide

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🏭 Roman Lifesciences Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 23, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate for symptomatic relief of productive cough.
Reviewed by
SaathiMed Expert Panel | Oct 23, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or worsening asthma
  • Swelling of face, lips, or throat
  • Severe skin rash or blistering
  • Yellowing of skin or eyes
  • Blood in cough or vomit
  • Severe stomach pain or persistent vomiting
  • Unusual bruising or bleeding

If experiencing severe symptoms, call emergency services immediately.

What is cherifon syrup used for?

This medicine is a combination syrup of bromhexine and guaifenesin used to loosen thick mucus and relieve chest congestion in conditions like bronchitis and productive cough. It is taken orally with food, usually two to three times a day, and should not be used for a dry cough.

  • Generic Name: Bromhexine + Guaifenesin
  • Manufacturer: Roman Lifesciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cherifon syrup के बारे में (Hindi Summary)

उपयोग: यह दवा ब्रोमहेक्सिन और गुआइफेनेसिन का मिश्रण है, जिसका उपयोग छाती में जमा गाढ़े बलगम को पतला करने और खांसी को आसान बनाने के लिए किया जाता है। यह ब्रोंकाइटिस, सर्दी-जुकाम और अन्य श्वसन संक्रमणों में बलगम वाली खांसी के इलाज में मदद करती है। यह दवा सूखी खांसी के लिए नहीं है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, उल्टी, पेट दर्द, दस्त, सिरदर्द और चक्कर आना शामिल हैं। कभी-कभी एलर्जी, त्वचा पर चकत्ते, सूजन या सांस लेने में कठिनाई हो सकती है। अगर ऐसा हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे खाने के बाद लें ताकि पेट खराब न हो। दिनभर पर्याप्त पानी पिएं। शराब न पिएं। अगर आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। 7 दिन से ज्यादा खांसी रहने पर डॉक्टर से मिलें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 cherifon syrup Uses & Benefits

[{"condition":"Productive cough with thick mucus","description":"Helps loosen thick mucus in the airways and makes it easier to cough out phlegm.","evidence":"Well-established for short-term symptomatic relief"},{"condition":"Acute bronchitis","description":"Used as supportive therapy to relieve chest congestion and make cough more productive.","evidence":"Commonly used, evidence is supportive"},{"condition":"Chronic bronchitis","description":"May help clear mucus in people with chronic bronchitis when prescribed by a clinician.","evidence":"Limited to supportive use"},{"condition":"Upper respiratory tract infections with mucus","description":"Used for short-term relief of cough and congestion associated with common cold and similar infections.","evidence":"Symptomatic use only"}]

Off-label uses: [{"condition":"Pre-operative airway clearance in selected patients","description":"Sometimes used to loosen secretions before certain respiratory procedures, but this is not a standard approved use.","evidence":"Limited"},{"condition":"Sinusitis with thick secretions","description":"Occasionally used to help thin nasal and sinus secretions, but evidence is not strong.","evidence":"Limited"}]

Primary treatment for: Productive cough with thick mucus

Also treats: Acute bronchitis, Chronic bronchitis, Upper respiratory tract infections with mucus

📋 Drug Information

Generic Name(s)Bromhexine + Guaifenesin
Brand NameAscoril Plus Expectorant
ManufacturerRoman Lifesciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic and Expectorant
Route of AdministrationOral
StorageStore at room temperature, below 30°C, in a dry place. Protect from direct sunlight. Do not freeze. Keep the bottle tightly closed and out of the reach of children.
Shelf Life24 months from the date of manufacture, or as printed on the pack.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with or after food to reduce stomach upset.
2
Drink plenty of water throughout the day to help thin the mucus.
3
Do not use this medicine for a dry cough that does not produce mucus.
4
Avoid taking other cough and cold medicines that contain guaifenesin or bromhexine.
5
Do not exceed the dose or duration advised by your doctor.
6
Consult your doctor if symptoms do not improve within 7 days.
7
Avoid alcohol while taking this medicine.
8
Report any unusual skin rash, mouth ulcers, or yellowing of eyes to your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
❌
Dry cough
This medicine is not meant for dry cough.
Not Primary
✅
Chest congestion
This medicine helps loosen mucus and relieve congestion.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBromhexine and guaifenesin are absorbed from the gastrointestinal tract after oral administration. The exact absorption characteristics of this fixed-dose syrup are not established from the available information.
DistributionBoth bromhexine and guaifenesin are distributed to body tissues, including the respiratory tract. Specific distribution data for this combination syrup are not established from the available information.
Protein BindingNot established from the available information.
MetabolismBromhexine undergoes extensive metabolism in the liver, mainly by first-pass metabolism, to several metabolites. Guaifenesin is also metabolized in the liver. Detailed metabolic data for this fixed-dose combination are not established from the available information.
Half-LifeNot established from the available information.
ExcretionBromhexine and its metabolites are mainly excreted in the urine, and guaifenesin metabolites are also excreted in the urine. Specific excretion data for this combination syrup are not established from the available information.
BioavailabilityBromhexine has low oral bioavailability because of extensive first-pass metabolism. The bioavailability of guaifenesin from this syrup is not established from the available information.
Onset of ActionSymptomatic relief of chest congestion usually begins within 30 to 60 minutes after taking a dose, but this can vary from person to person.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effect of a single dose generally lasts for about 4 to 6 hours, depending on the individual and the severity of congestion.

How It Works

This medicine works through two complementary actions. Bromhexine is a mucolytic that reduces the thickness and stickiness of mucus by breaking down the structure of mucus glycoproteins and by stimulating the production of thinner secretions. Guaifenesin is an expectorant that increases the volume and reduces the viscosity of respiratory tract secretions, making coughs more productive and easier to clear. Together, they help move mucus out of the airways and provide symptomatic relief from chest congestion.

Mechanism Steps

1
Bromhexine breaks down mucus structure: Bromhexine reduces the thickness of mucus by breaking down the network of mucus glycoproteins and by promoting the secretion of thinner mucus from the airways.
2
Guaifenesin increases mucus water content: Guaifenesin increases the water content of respiratory secretions, which lowers viscosity and makes the mucus easier to cough out.
3
Combined effect on mucus clearance: The two ingredients work together to loosen thick secretions and support the natural clearing action of the cough reflex.
4
Symptomatic relief of chest congestion: As mucus becomes thinner and easier to move, patients experience less chest congestion and a more productive cough.

💡 How to Take cherifon syrup

Strength: Each 5 mL of syrup contains bromhexine 8 mg and guaifenesin 50 mg.

1Shake the bottle well before each use.
2Measure the prescribed dose using the measuring cup or spoon provided.
3Take the medicine with or after food to reduce stomach upset.
4Drink a glass of water after taking the dose.
5Do not mix the medicine with hot drinks.
6Close the bottle tightly after use.

Dosage Information

Adult DosageThe usual adult dose of this syrup is 5 to 10 mL taken two to three times a day, depending on the severity of congestion and the advice of your doctor. Do not exceed the dose recommended by your clinician. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Shake the bottle well before use and measure the dose with the measuring cup provided.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageOlder adults may be more sensitive to the side effects of this medicine, especially dizziness and drowsiness. Use with caution and follow the dose advised by your doctor. Dose must be individualized by a qualified clinician based on renal and hepatic function.
Renal ImpairmentUse with caution in people with severe kidney disease. Dose adjustment may be needed. Consult your doctor before use.
Hepatic ImpairmentUse with caution in people with severe liver disease. Dose adjustment may be needed. Consult your doctor before use.
Maximum Daily DoseThe maximum daily dose should not exceed the limit recommended by your doctor. For adults, the usual maximum is 30 mL per day of this syrup, but this must be confirmed by your clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Water
Drink plenty
Helps thin mucus.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of cherifon syrup

✅ Common Side Effects

Nausea (Common)
Take the medicine with or after food. If nausea continues, consult your doctor.
Stomach upset or pain (Common)
Take with food and avoid spicy meals. Consult your doctor if it persists.
Vomiting (Uncommon)
Stop the medicine and consult your doctor if vomiting is severe or repeated.
Diarrhea (Uncommon)
Drink plenty of fluids. Consult your doctor if diarrhea lasts more than a day.
Headache (Uncommon)
Rest and stay hydrated. Consult your doctor if the headache is severe or persistent.
Dizziness or drowsiness (Uncommon)
Avoid driving or operating machinery until you know how this medicine affects you.

🚨 Serious Side Effects

Severe allergic reaction with swelling of face, lips, or throat (Rare)
Stop the medicine and seek emergency medical help immediately.
Severe skin reactions such as blistering or peeling skin (Very rare)
Stop the medicine and seek immediate medical attention.
Liver problems with yellowing of skin or eyes (Very rare)
Stop the medicine and consult a doctor urgently for liver function tests.
Difficulty breathing or worsening of asthma (Rare)
Seek immediate medical help if breathing becomes difficult.

⚠️ Rare Side Effects

Severe skin reactions
Stop the medicine and seek immediate medical attention.
Liver enzyme elevation
Consult a doctor for liver function tests if you notice yellowing of eyes or skin.
Blood disorders such as low platelet count
Report unusual bruising or bleeding to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Other guaifenesin or bromhexine products Major
Amoxicillin Moderate
Cefuroxime Moderate
Erythromycin Moderate
Doxycycline Moderate
Sedatives and antihistamines Moderate
Alcohol Moderate
Antacids Minor

🚨 Major Interactions

  • Other cough and cold medicines containing guaifenesin or bromhexine
  • Antibiotics such as amoxicillin, cefuroxime, erythromycin, and doxycycline

⚡ Moderate Interactions

  • Medicines that cause drowsiness such as sedatives and antihistamines
  • Alcohol

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and stomach irritation, and it may worsen the underlying condition.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Allergy to bromhexine, guaifenesin, or any other ingredient of this product","Children below the age recommended by the manufacturer or clinician","Active stomach ulcer or bleeding in the stomach","Severe liver disease","Severe kidney disease","Use in patients who cannot cough out secretions effectively without medical supervision"]

⚠️ Warnings & Precautions

["Do not use this medicine for a dry cough that does not produce mucus.","Do not take more than the recommended dose or use it for longer than advised.","Use with caution in people with asthma or other breathing problems.","Use with caution in people with stomach ulcers or a history of stomach bleeding.","Consult a doctor before use if you are pregnant, planning pregnancy, or breastfeeding.","Avoid alcohol while taking this medicine.","Keep out of reach of children.","If symptoms do not improve within 7 days or worsen, stop the medicine and consult a doctor."]

🤱 Lactation Safety

It is not known whether bromhexine and guaifenesin pass into breast milk in significant amounts. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose of this medicine may cause nausea, vomiting, diarrhea, stomach pain, dizziness, and drowsiness. If you suspect an overdose, stop the medicine and seek immediate medical attention. Treatment is supportive and based on the symptoms. Do not try to induce vomiting unless told to do so by a healthcare professional.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it for longer than advised. Shake the bottle well before each use and measure the dose with the measuring cup or spoon provided. Take it with or after food to reduce stomach upset. Drink plenty of water throughout the day because fluids help guaifenesin thin the mucus. Do not take this medicine with other cough and cold products that also contain guaifenesin or bromhexine, as this can lead to overdose. Avoid alcohol while taking this medicine because it can increase drowsiness and stomach irritation. If you are pregnant, planning pregnancy, or breastfeeding, talk to your doctor before using this medicine. Keep this medicine out of the reach of children. Do not use it for a dry, irritating cough that produces no mucus, as it is not meant for that type of cough. If your cough lasts more than 7 days, comes back, or is accompanied by fever, rash, or persistent headache, stop the medicine and consult your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Older adults may be more sensitive to side effects such as dizziness and drowsiness. Use with caution and follow the dose advised by your doctor. Ensure adequate hydration.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy or are pregnant, consult your doctor before using this medicine. The safety of this medicine during pregnancy is not well established.

🏥 Post-Surgery Considerations

If you have recently had surgery, consult your doctor before using this medicine, especially if you are taking other medicines or have difficulty coughing.

🦷 Dental Procedures

No specific precautions are established for dental procedures. Inform your dentist about all medicines you are taking.

💚 Lifestyle Tips for Better Results

🏃
Drink plenty of water throughout the day to help thin mucus.
🥗
Use a humidifier or take steam inhalation to ease chest congestion.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Get adequate rest to help your body recover.
🧘
Eat a balanced diet rich in fruits and vegetables.
🌞
Wash your hands frequently to prevent infections.

🏋️ Exercise Considerations

Avoid strenuous exercise if you have fever or severe chest congestion. Light activity such as walking is fine if you feel up to it. Consult your doctor before starting any exercise routine while you are unwell.

🥗 Diet Recommendations

Drink warm fluids like soups and herbal teas.
Include vitamin C rich foods such as oranges and amla.
Avoid cold drinks and ice cream.
Avoid spicy and oily foods that can irritate the stomach.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. Take rest if you feel unwell. It is usually safe to continue light desk work.

🛑 When to Stop This Medicine

Stop this medicine if your cough improves or as advised by your doctor. If symptoms do not improve within 7 days, or if you develop fever, rash, or difficulty breathing, stop the medicine and consult a doctor. Do not stop any prescribed medicine without consulting your doctor.

📅 Long-Term Use Effects

This medicine is intended for short-term use. Long-term use is not recommended without medical supervision. Prolonged use may increase the risk of side effects such as stomach upset and, rarely, liver problems. If your symptoms persist beyond 7 days, consult a doctor for further evaluation.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and relieve chest congestion.

Evidence: Supportive
Saline nasal irrigation

Helps clear nasal congestion and post-nasal drip.

Evidence: Supportive
Honey and warm water

May soothe the throat and reduce cough frequency.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are unwell with fever, it is better to postpone vaccination until you recover. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Keep a copy of your prescription with you. Store it at room temperature and protect it from direct sunlight. If you are traveling across time zones, continue your doses at regular intervals as advised by your doctor. Check the customs rules of your destination country for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis and thick chest mucus
He was prescribed this medicine along with rest and fluids. After two days, he noticed that his cough became more productive and chest congestion reduced. He took the syrup with food as advised and drank plenty of water.
💡 Lesson: Taking this medicine with food and staying hydrated improves tolerability and helps clear mucus.
👤 A 50-year-old woman with chronic bronchitis
She used this medicine for short-term relief during flare-ups. She found that it helped loosen mucus, but she needed to stop after 7 days as advised by her doctor. She also avoided alcohol and other cough syrups.
💡 Lesson: This medicine is for short-term use. Do not use it for longer than advised without consulting a doctor.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Symptomatic relief usually begins within 30 to 60 minutes after taking a dose, but this can vary.

Q: Can I take this medicine for dry cough?

A: No, this medicine is only for cough with thick mucus. It is not effective for dry cough.

Q: Is it safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician.

Q: Can I take it with antibiotics?

A: Bromhexine may increase the levels of some antibiotics in lung tissue. Use only if prescribed together by a clinician.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for cherifon syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: This medicine is only for cough with thick mucus. It is not effective for dry cough or cough due to allergies.
  • Myth: More syrup means faster relief.
    Fact: Taking more than the recommended dose does not speed up recovery and can cause side effects.
  • Myth: It is safe to take with other cough syrups.
    Fact: Taking multiple cough syrups together can lead to overdose of similar ingredients. Always check with your doctor.

🔄 Alternative Options

Generic Alternatives

  • Bromhexine and guaifenesin syrup
  • Bromhexine syrup
  • Guaifenesin syrup

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","active_ingredients":"Bromhexine + Guaifenesin","main_use":"Productive cough with thick mucus","route":"Oral"},{"medicine":"Ambroxol syrup","active_ingredients":"Ambroxol","main_use":"Productive cough with thick mucus","route":"Oral"},{"medicine":"Acetylcysteine syrup","active_ingredients":"Acetylcysteine","main_use":"Thick mucus in respiratory conditions","route":"Oral"}]

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