Synabron Expectorant: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in sputum or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Persistent fever
If experiencing severe symptoms, call emergency services immediately.
What is synabron expectorant used for?
This medicine is a combination expectorant containing Bromhexine and Guaifenesin. It helps loosen thick mucus in the airways, making it easier to cough out. It is used for productive cough and should not be used for dry cough.
- Generic Name: Bromhexine (8mg) + Guaifenesin (50mg)
- Manufacturer: Concept Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 synabron expectorant के बारे में (Hindi Summary)
उपयोग: यह दवा ब्रोमहेक्सिन और गुआइफेनेसिन का संयोजन है, जो कफ को पतला करके बाहर निकालने में मदद करती है। यह गले में जमा बलगम को ढीला करती है और खांसी को आसान बनाती है। इसका उपयोग बलगम वाली खांसी, ब्रोंकाइटिस और श्वसन संबंधी समस्याओं में किया जाता है। सूखी खांसी में इसका उपयोग नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, सिरदर्द, चक्कर आना और पेट में गड़बड़ी शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको त्वचा पर चकत्ते, सूजन, सांस लेने में कठिनाई या गंभीर एलर्जी के लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अधिक मात्रा में न लें। दवा लेते समय पर्याप्त पानी पिएं। 7 दिनों से अधिक इसका उपयोग बिना डॉक्टर की सलाह के न करें। यदि खांसी के साथ बुखार, दाने या लगातार सिरदर्द हो तो डॉक्टर से मिलें। गर्भवती या स्तनपान कराने वाली महिलाएं बिना सलाह के इसका उपयोग न करें। चक्कर आने पर वाहन न चलाएं। बच्चों की पहुंच से दूर रखें।
💊 synabron expectorant Uses & Benefits
[{"condition":"Productive cough","description":"Helps loosen thick mucus and makes it easier to cough out, providing relief in cough with phlegm.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Used as a supportive treatment to clear mucus from the airways in acute bronchitis.","evidence":"Moderate"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"May help in clearing mucus in COPD patients, but not a primary treatment.","evidence":"Limited"}]
Off-label uses: [{"condition":"Sinusitis","description":"Sometimes used to thin mucus in sinus infections, but not a standard treatment.","evidence":"Limited"},{"condition":"Otitis media with effusion","description":"Occasionally used to help clear middle ear fluid, but evidence is weak.","evidence":"Limited"}]
Primary treatment for: Productive cough
Also treats: Acute bronchitis, Chronic obstructive pulmonary disease (COPD)
📋 Drug Information
| Generic Name(s) | Bromhexine (8mg) + Guaifenesin (50mg) |
| Brand Name | synabron expectorant |
| Manufacturer | Concept Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the container tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two mucoactive agents. Bromhexine is a mucolytic that breaks down acidic mucopolysaccharide fibers in mucus, reducing its viscosity and making it easier to expel. Guaifenesin is an expectorant that increases the volume and reduces the viscosity of secretions in the respiratory tract by increasing water content, thereby promoting ciliary action and facilitating the removal of mucus. Together, they improve cough clearance.
Mechanism Steps
💡 How to Take synabron expectorant
Strength: Each 5 mL contains Bromhexine 8 mg and Guaifenesin 50 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 10 mL (containing Bromhexine 8 mg and Guaifenesin 50 mg) taken two to three times daily, or as directed by your doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Dose adjustment may be needed based on kidney and liver function. Consult your doctor for appropriate dosing. |
| Renal Impairment | Dose adjustment may be required in patients with kidney disease. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | Dose adjustment may be required in patients with liver disease. Consult your doctor for appropriate dosing. |
| Maximum Daily Dose | The maximum daily dose is 30 mL (containing Bromhexine 24 mg and Guaifenesin 150 mg) in divided doses, unless otherwise prescribed by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of synabron expectorant
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Codeine | Major | |
| Dextromethorphan | Major | |
| Amoxicillin | Moderate | |
| Cefuroxime | Moderate | |
| Atropine | Moderate | |
| Diuretics | Minor |
🚨 Major Interactions
- Cough suppressants (e.g., codeine, dextromethorphan)
⚡ Moderate Interactions
- Antibiotics (e.g., amoxicillin, cefuroxime)
- Anticholinergic drugs (e.g., atropine)
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, drowsiness, and stomach upset while taking this medicine. It is advisable to avoid alcohol during treatment.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Bromhexine, Guaifenesin, or any component of the formulation.","Dry, non-productive cough.","Children under 12 years of age (unless prescribed by a doctor).","Severe liver or kidney disease (unless directed by a doctor)."]
⚠️ Warnings & Precautions
["Do not use for dry cough.","Do not exceed the recommended dose.","Consult a doctor if cough persists for more than 7 days or is accompanied by fever, rash, or persistent headache.","Use with caution in patients with liver or kidney disease.","Avoid alcohol while taking this medicine.","Do not use in children under 12 years without medical advice.","If you are pregnant or breastfeeding, consult your doctor before use.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether Bromhexine and Guaifenesin pass into breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhea, and abdominal discomfort. Seek immediate medical attention if you suspect an overdose. Treatment is symptomatic and supportive.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose. Drink plenty of water while taking this medicine to help loosen mucus. Avoid taking this medicine for more than 7 days without consulting your doctor. If your cough is accompanied by fever, rash, or persistent headache, consult a doctor before using this medicine. Do not use this medicine if you are pregnant or breastfeeding without medical advice. Avoid driving or operating heavy machinery if you feel dizzy after taking this medicine. Keep this medicine out of reach of children. Do not use this medicine after the expiry date. If you have liver or kidney problems, inform your doctor before taking this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and gastrointestinal upset. Dose adjustment may be needed based on kidney and liver function. Consult your doctor.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is not known whether this medicine is safe during pregnancy.
🏥 Post-Surgery Considerations
If you have recently had surgery, consult your doctor before taking this medicine, as it may affect wound healing or interact with other medications.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may cause dry mouth, which can affect dental work.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you have a severe cough or breathing difficulty. Light activity like walking may be beneficial, but consult your doctor before starting any exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is usually safe to continue desk work.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your cough persists for more than 7 days, or if you experience severe side effects. Do not stop abruptly if you have been on it for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use may lead to electrolyte imbalance or gastrointestinal disturbances. Regular monitoring of liver and kidney function may be advised if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and relieve congestion.
Evidence: Well-establishedCan help clear nasal congestion and postnasal drip.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are due for a vaccine, inform your doctor about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If traveling across time zones, continue your regular dosing schedule as close as possible. Check customs regulations for carrying liquid medicines. Keep it in your carry-on luggage if you need it during the flight.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 minutes to 1 hour after taking a dose.
A: Yes, but inform your doctor. Bromhexine may increase antibiotic levels in the lungs, which can be beneficial.
A: It is not recommended for children under 12 years without medical advice.
🤔 Common Patient Concerns
🔄 Substitutes for synabron expectorant
View AllAlternative brands with exact same active ingredient:
-
expal tabletMech Pharmaceuticals ₹22.72 49.5% CHEAPER
-
cherifon syrupRoman Lifesciences Pvt Ltd ₹40.77 9.4% CHEAPER
-
vincolyte br syrupVision Biotech ₹62.00 37.8% COSTLIER
-
synabron plus expectorant sugar freeConcept Pharmaceuticals Ltd ₹90.00 100% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of cough.
Fact: It is only effective for productive cough with mucus. It does not treat dry cough. - Myth: It is safe to take with other cough syrups.
Fact: Combining with cough suppressants can be harmful. Always consult a doctor.
🔄 Alternative Options
Generic Alternatives
- Bromhexine + Guaifenesin syrup
Brand Alternatives
- Synabron Expectorant