broxine 2mg/8mg tablet - Salbutamol (2mg) + Bromhexine (8mg) medicine

Asthavil Tablet: Comprehensive Medicine Guide

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🏭 Healthy Life Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for symptomatic relief in productive cough with bronchospasm; limited for some off-label uses.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe chest pain or tightness
  • Racing, pounding, or irregular heartbeat
  • Difficulty breathing or worsening breathlessness after taking the medicine
  • Swelling of face, lips, tongue, or throat
  • Severe dizziness or fainting
  • Yellowing of skin or eyes, or dark urine
  • Severe muscle weakness or cramps

If experiencing severe symptoms, call emergency services immediately.

What is broxine 2mg/8mg tablet used for?

This medicine is a combination of salbutamol (a bronchodilator) and bromhexine (a mucolytic) used to relieve productive cough with bronchospasm. It helps open airways and thin mucus, making it easier to cough out. It is taken orally, usually two to three times a day after food, as prescribed by a doctor.

  • Generic Name: Salbutamol (2mg) + Bromhexine (8mg)
  • Manufacturer: Healthy Life Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 broxine 2mg/8mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा सल्बुटामोल और ब्रोमहेक्सिन का संयोजन है, जिसका उपयोग बलगम वाली खांसी और सांस की नली में संकुचन (ब्रोंकोस्पाज्म) के इलाज के लिए किया जाता है। सल्बुटामोल सांस की नलियों को फैलाकर सांस लेना आसान बनाता है, जबकि ब्रोमहेक्सिन गाढ़े बलगम को पतला करके बाहर निकालने में मदद करता है। यह दवा ब्रोंकाइटिस, अस्थमा और अन्य श्वसन रोगों में लक्षणों से राहत देने के लिए दी जाती है। इसे डॉक्टर की सलाह के अनुसार ही लें, खासकर अगर आपको हृदय रोग, उच्च रक्तचाप या थायरॉइड की समस्या है।

साइड इफेक्ट्स: आम दुष्प्रभावों में हाथों में कंपन, धड़कन तेज होना, घबराहट, सिरदर्द, जी मिचलाना और पेट में गड़बड़ी शामिल हैं। कभी-कभी मांसपेशियों में ऐंठन, चकत्ते या सांस लेने में कठिनाई भी हो सकती है। अगर आपको तेज धड़कन, सीने में दर्द, चेहरे या गले में सूजन या सांस लेने में गंभीर परेशानी हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर खाने के बाद दिन में दो से तीन बार। इसे पानी के साथ पूरा निगलें, चबाएं नहीं। अचानक तेज सांस फूलने पर इसका उपयोग रेस्क्यू इनहेलर की तरह न करें। अगर आपको दिल की बीमारी, उच्च रक्तचाप, मधुमेह या थायरॉइड की समस्या है, तो डॉक्टर को बताएं। शराब और कैफीन से बचें। बिना डॉक्टर की सलाह के दवा बंद या डोज न बदलें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 broxine 2mg/8mg tablet Uses & Benefits

[{"condition":"Productive cough with bronchospasm in acute bronchitis","description":"Helps loosen thick mucus and relax airway muscles, making cough more productive and easing breathing.","evidence":"Commonly used; supportive evidence from clinical practice"},{"condition":"Chronic bronchitis with thick secretions","description":"Provides symptomatic relief by reducing mucus viscosity and mild bronchodilation.","evidence":"Commonly used; supportive evidence from clinical practice"},{"condition":"Asthma with mucus plugging (adjunctive)","description":"May be used as an add-on to inhaled therapy when thick secretions are a prominent feature.","evidence":"Limited; not a replacement for inhaled corticosteroids or rescue inhalers"},{"condition":"Respiratory tract disorders with tenacious mucus","description":"Used to ease expectoration when cough is associated with thick, sticky sputum.","evidence":"Commonly used; supportive evidence from clinical practice"}]

Off-label uses: [{"condition":"Smoker's cough with mucus","description":"Sometimes used to help clear secretions in chronic smokers, but not a standard approved indication.","evidence":"Limited"},{"condition":"Post-infectious cough with mucus","description":"Occasionally prescribed after respiratory infections to aid mucus clearance.","evidence":"Limited"}]

Primary treatment for: Productive cough with bronchospasm

Also treats: Acute bronchitis, Chronic bronchitis, Asthma with mucus plugging, Respiratory tract infections with thick secretions

📋 Drug Information

Generic Name(s)Salbutamol (2mg) + Bromhexine (8mg)
Brand Namebroxine 2mg/8mg tablet
ManufacturerHealthy Life Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine after food to reduce stomach upset and nausea.
2
Do not use this as a rescue medicine for sudden severe breathlessness; keep your inhaler handy.
3
Avoid caffeine and alcohol while taking this medicine to reduce palpitations and tremor.
4
Report persistent palpitations, chest pain, or muscle weakness to your doctor promptly.
5
Do not continue this medicine for more than 7 days without medical review.
6
Inform your doctor about all other medicines you take, especially beta-blockers and diuretics.
7
If you have diabetes, monitor blood sugar as salbutamol can raise glucose levels.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
✅
Wheezing with mucus
May be used as an adjunct for bronchospasm with secretions.
Likely Use
❌
Dry cough
This medicine is not primarily for dry cough.
Not Primary
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSalbutamol is well absorbed from the gastrointestinal tract after oral administration, but oral bioavailability is reduced by first-pass metabolism in the liver and gut wall. Bromhexine is also absorbed from the gastrointestinal tract. Not established from the available information for exact absorption percentages of this specific combination.
DistributionSalbutamol is widely distributed into body tissues and crosses the placenta; it is also excreted in breast milk. Bromhexine distributes into lung tissue and bronchial secretions. Not established from the available information for exact volume of distribution of this combination.
Protein BindingSalbutamol is approximately 10% bound to plasma proteins. Bromhexine and its metabolites are highly bound to plasma proteins, but exact values are not established from the available information for this combination.
MetabolismSalbutamol undergoes extensive first-pass metabolism in the liver, mainly by conjugation to inactive sulfate esters. Bromhexine is metabolized in the liver to several metabolites, including ambroxol. Not established from the available information for exact metabolic pathways of this specific combination.
Half-LifeThe elimination half-life of salbutamol is approximately 4 to 6 hours. The elimination half-life of bromhexine is not established from the available information for this combination.
ExcretionSalbutamol and its metabolites are excreted mainly in the urine, with a smaller amount in feces. Bromhexine metabolites are excreted primarily in the urine. Not established from the available information for exact excretion percentages of this combination.
BioavailabilityOral salbutamol has a bioavailability of approximately 40% due to first-pass metabolism. The bioavailability of bromhexine in this combination is not established from the available information.
Onset of ActionBronchodilation from oral salbutamol usually begins within 15 to 30 minutes, but the full effect may take longer. The mucolytic effect of bromhexine develops gradually over hours to days.
Peak Plasma TimePeak plasma levels of salbutamol after oral administration are reached in about 2 to 4 hours. Peak plasma time for bromhexine is not established from the available information for this combination.
Duration of ActionThe bronchodilator effect of oral salbutamol lasts approximately 4 to 6 hours. The mucolytic effect of bromhexine lasts longer and may require regular dosing for cumulative benefit.

How It Works

Salbutamol selectively stimulates beta-2 adrenergic receptors on bronchial smooth muscle, which increases cyclic AMP and causes relaxation of the airway muscles, leading to bronchodilation. Bromhexine increases serous bronchial secretion and breaks down acidic mucopolysaccharide fibers in mucus, reducing its viscosity and making it easier to cough out. The combination addresses both airway narrowing and thick mucus, providing symptomatic relief in productive cough with bronchospasm.

Mechanism Steps

1
Beta-2 receptor stimulation: Salbutamol binds to beta-2 adrenergic receptors on bronchial smooth muscle cells.
2
Increased cyclic AMP: This binding activates adenylate cyclase, raising cyclic AMP levels inside the muscle cells.
3
Bronchial smooth muscle relaxation: The rise in cyclic AMP causes the airway muscles to relax, widening the bronchi and easing breathing.
4
Mucus breakdown by bromhexine: Bromhexine breaks down acidic mucopolysaccharide fibers in mucus, reducing its thickness and stickiness.
5
Improved mucus clearance: Thinner mucus is easier to cough up, helping clear the airways and relieve congestion.

💡 How to Take broxine 2mg/8mg tablet

Strength: Each tablet contains salbutamol 2 mg and bromhexine 8 mg.

1Swallow the tablet whole with a full glass of water.
2Take it after food to reduce stomach upset.
3Do not crush, chew, or break the tablet unless advised by your doctor.
4Take it at the same times each day to maintain consistent levels.
5If you miss a dose, follow the missed dose instructions.
6Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet two to three times a day, taken orally after food. The exact dose and frequency must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, and renal and hepatic function. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may be more sensitive to the cardiovascular effects of salbutamol. Use with caution and individualize the dose based on renal and hepatic function and overall health status. Consult a doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be required in patients with severe renal impairment. Consult a doctor for individualized dosing.
Hepatic ImpairmentDose adjustment may be required in patients with severe hepatic impairment. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is not established from the available information for this specific combination. Do not exceed the dose prescribed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take after meals
Reduces stomach upset and nausea.
Caffeine
Limit
May worsen tremor and palpitations.
Alcohol
Avoid
May increase dizziness and heart rate changes.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of broxine 2mg/8mg tablet

✅ Common Side Effects

Fine tremor of hands (Common (5-10%))
Usually reduces with continued use. Avoid caffeine and report if it interferes with daily activities.
Palpitations or fast heartbeat (Common (5-10%))
Report to your doctor if persistent or associated with chest discomfort.
Nervousness or restlessness (Common (5-10%))
Usually temporary. Practice relaxation techniques and avoid stimulants.
Headache (Common (5-10%))
Stay hydrated and rest. Consult doctor if severe or persistent.
Nausea or stomach upset (Common (5-10%))
Take the tablet after food with a full glass of water.
Muscle cramps (Uncommon (1-5%))
Report to doctor if frequent; may indicate low potassium levels.

🚨 Serious Side Effects

Severe palpitations or irregular heartbeat (Rare (<0.1%))
Seek immediate medical attention if you experience a racing, pounding, or irregular heartbeat.
Chest pain or tightness (Rare (<0.1%))
Stop the medicine and seek emergency care immediately.
Severe allergic reaction (swelling of face, lips, throat, difficulty breathing) (Rare (<0.1%))
Call emergency services immediately; do not wait.
Low potassium levels with muscle weakness (Rare (<0.1%))
Consult your doctor for blood tests if you develop persistent weakness or cramps.
Severe skin rash or blistering (Rare (<0.1%))
Stop the medicine and seek medical advice promptly.

⚠️ Rare Side Effects

Paradoxical bronchospasm
Stop the medicine and seek immediate medical help if breathing worsens after taking it.
Hallucinations or confusion
Report to your doctor immediately; may require dose adjustment or discontinuation.
Severe liver enzyme elevation
Seek medical attention if you notice yellowing of eyes or skin, dark urine, or severe fatigue.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Tricyclic antidepressants Major
Diuretics Major
Corticosteroids Major
Digoxin Moderate
Pseudoephedrine Moderate
Ipratropium Moderate
Caffeine Minor
Antacids Minor

🚨 Major Interactions

  • Non-selective beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants
  • Potassium-lowering drugs (e.g., diuretics, corticosteroids, xanthines)

⚡ Moderate Interactions

  • Digoxin
  • Other sympathomimetics (e.g., pseudoephedrine, adrenaline)
  • Anticholinergic bronchodilators (e.g., ipratropium)

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and cardiovascular side effects such as palpitations. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to salbutamol, bromhexine, or any component of the formulation","Severe cardiovascular disease including severe heart failure, uncontrolled arrhythmias, or recent myocardial infarction","Severe uncontrolled hypertension","Hyperthyroidism","Severe hepatic or renal impairment without medical supervision","Children under 12 years unless specifically prescribed by a pediatrician"]

⚠️ Warnings & Precautions

["This medicine should not be used as a substitute for inhaled rescue bronchodilators in acute severe asthma.","Use with caution in patients with heart disease, hypertension, diabetes, or hyperthyroidism.","Salbutamol can cause hypokalemia; monitor potassium levels if used at high doses or with other potassium-lowering drugs.","Bromhexine may cause gastrointestinal upset; taking it after food reduces this risk.","Do not exceed the recommended dose; excessive use may lead to severe cardiovascular effects.","Consult a doctor if symptoms persist beyond 7 days or worsen.","Avoid alcohol and caffeine while taking this medicine.","Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding."]

🤱 Lactation Safety

Salbutamol is excreted in breast milk in small amounts and is generally considered compatible with breastfeeding. It is not known whether bromhexine is excreted in human milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose may cause severe tachycardia, palpitations, tremor, restlessness, chest pain, and hypokalemia. Seek immediate medical attention. Treatment is supportive and symptomatic, including monitoring of vital signs, electrolytes, and cardiac rhythm. There is no specific antidote for this combination.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor, usually two to three times a day for adults, and do not exceed the recommended dose. Swallow the tablet whole with a glass of water, preferably after food to reduce stomach upset. Do not use this medicine as a rescue inhaler for sudden severe breathlessness; always keep your prescribed inhaler available. Inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, or low potassium levels. Avoid alcohol because it can worsen dizziness and heart rate changes. Do not stop or change the dose without consulting your doctor, and report any persistent palpitations, tremor, or rash promptly.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to cardiovascular side effects such as palpitations and arrhythmias. Use with caution, monitor heart rate and blood pressure, and adjust dose as needed based on renal and hepatic function.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Salbutamol is generally considered acceptable when needed, but bromhexine should be used only if clearly indicated. Discuss all medicines with your obstetrician.

🏥 Post-Surgery Considerations

Consult your surgeon and anesthesiologist before taking this medicine after surgery. Salbutamol can affect heart rate and potassium levels, which may be relevant during recovery. Do not start or stop without medical advice.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may cause dry mouth or tremor, which can affect dental procedures. No specific precautions are usually required, but maintain good oral hygiene.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke.
🥗
Stay well hydrated to help thin mucus.
😴
Use a humidifier in dry environments to ease breathing.
💧
Practice deep breathing exercises as advised by your doctor.
🧘
Get adequate rest to support recovery from respiratory infections.
🌞
Maintain good hand hygiene to prevent respiratory infections.

🏋️ Exercise Considerations

Avoid strenuous exercise if you experience palpitations, dizziness, or breathlessness. Mild activity like walking may be beneficial, but consult your doctor before starting any exercise program while on this medicine.

🥗 Diet Recommendations

Drink plenty of warm fluids to help loosen mucus.
Include fruits and vegetables rich in vitamin C and antioxidants.
Avoid cold drinks and ice cream if they trigger cough.
Limit caffeine and alcohol.
Eat small, frequent meals if you have nausea.

💼 Impact on Daily Work & Life

This medicine may cause tremor, dizziness, or palpitations, which can affect driving or operating machinery. Avoid these activities if you feel unwell. It is usually taken for a short duration, so work impact is limited. Inform your employer if you need to take it during work hours.

🛑 When to Stop This Medicine

Stop this medicine if your doctor advises, if symptoms resolve, or if you experience serious side effects such as severe palpitations, chest pain, or allergic reactions. Do not stop abruptly if you have an underlying chronic respiratory condition without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine without medical supervision may lead to tolerance to salbutamol's effects, increased cardiovascular risk, and electrolyte disturbances such as low potassium. Regular monitoring of heart rate, blood pressure, and potassium levels may be needed. It should not replace appropriate long-term management of asthma or chronic bronchitis.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and ease breathing; can complement medicine.

Evidence: Commonly used; supportive evidence
Chest physiotherapy

Techniques to help clear secretions in chronic respiratory conditions.

Evidence: Well-established for mucus clearance
Inhaled bronchodilators

Preferred for acute bronchospasm; this oral medicine is adjunctive.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you have a respiratory infection, consult your doctor about timing of vaccination. Annual influenza vaccination is recommended for people with chronic respiratory diseases.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Declare it at customs if required. Keep enough supply for the entire trip and carry it in your hand luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis and thick mucus
He was prescribed this medicine after food twice daily. Within three days, his cough became more productive and breathing felt easier. He avoided coffee and alcohol as advised, which helped reduce palpitations. He completed the prescribed course and recovered well.
💡 Lesson: Taking the medicine after food and avoiding stimulants improves tolerability and symptom relief.
👤 A 60-year-old woman with chronic bronchitis
She had persistent cough with thick sputum. Her doctor prescribed this medicine along with her regular inhaler. She noticed gradual improvement in mucus clearance over a week. She was advised not to stop her inhaler and to report any palpitations.
💡 Lesson: This medicine is adjunctive and should not replace regular inhaled therapy for chronic respiratory conditions.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Bronchodilation usually begins within 15 to 30 minutes, but the full benefit for mucus clearance may take a few days of regular use.

Q: Can I take it with food?

A: Yes, taking it after food is recommended to reduce stomach upset.

Q: Is it safe during pregnancy?

A: Consult your obstetrician. Salbutamol is generally considered acceptable when needed, but bromhexine should be used only if clearly needed.

Q: Can I stop it when I feel better?

A: Do not stop without consulting your doctor, especially if you have an underlying respiratory condition.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for broxine 2mg/8mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any type of cough.
    Fact: It is specifically for productive cough with bronchospasm, not for dry cough or infections requiring antibiotics.
  • Myth: More tablets will give faster relief.
    Fact: Taking more than prescribed can cause serious heart and potassium problems. Always follow the prescribed dose.
  • Myth: It is safe to take long-term without doctor supervision.
    Fact: Prolonged use requires medical review; it is intended for short-term symptom relief.

🔄 Alternative Options

Generic Alternatives

  • Salbutamol 2 mg + Bromhexine 8 mg tablet (generic)

Brand Alternatives

  • Asthavil Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine (Salbutamol + Bromhexine)","composition":"Salbutamol 2 mg + Bromhexine 8 mg","primary_use":"Productive cough with bronchospasm","route":"Oral"},{"medicine":"Salbutamol + Ambroxol","composition":"Salbutamol + Ambroxol","primary_use":"Productive cough with bronchospasm","route":"Oral"},{"medicine":"Bromhexine alone","composition":"Bromhexine","primary_use":"Thick mucus","route":"Oral"},{"medicine":"Salbutamol alone","composition":"Salbutamol","primary_use":"Bronchospasm","route":"Oral/Inhalation"}]

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