asmatide br 8 mg/4 mg/200 mg tablet - Bromhexine (8mg) + Salbutamol (4mg) medicine

Asmatide BR 8 mg/4 mg/200 mg Tablet: Complete Medicine Guide

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🏭 Systopic Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for individual components; combination evidence is moderate.
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or worsening of asthma symptoms
  • Chest pain or irregular heartbeat
  • Severe allergic reaction (rash, swelling of face, lips, or throat)
  • Muscle weakness or cramps (possible low potassium)
  • Severe headache or dizziness
  • Blood in mucus or vomit

If experiencing severe symptoms, call emergency services immediately.

What is asmatide br 8 mg/4 mg/200 mg tablet used for?

This medicine is a combination of bromhexine and salbutamol used to treat asthma, chronic bronchitis, and other obstructive airway diseases. It works by loosening mucus and relaxing airway muscles to make breathing easier.

  • Generic Name: Bromhexine + Salbutamol
  • Manufacturer: Systopic Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 asmatide br 8 mg/4 mg/200 mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा ब्रोमहेक्सिन और साल्बुटामोल का संयोजन है, जिसका उपयोग अस्थमा, क्रोनिक ब्रोंकाइटिस और अन्य श्वसन रोगों में किया जाता है। यह बलगम को पतला करके और श्वास नलियों की मांसपेशियों को आराम देकर सांस लेने में मदद करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, सिरदर्द, हाथ-पैर कांपना, धड़कन बढ़ना और पेट खराब होना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सांस लेने में कठिनाई, चकत्ते, या दिल की धड़कन अनियमित लगे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के बाद पानी के साथ निगलें, चबाएं नहीं। यदि आपको हृदय रोग, उच्च रक्तचाप, मधुमेह या थायरॉइड की समस्या है तो डॉक्टर को बताएं। इस दवा के सेवन के दौरान शराब न पिएं। गाड़ी चलाने या मशीन चलाने से बचें जब तक आपको इसका असर पता न चल जाए। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 asmatide br 8 mg/4 mg/200 mg tablet Uses & Benefits

[{"condition":"Asthma","description":"Helps relieve bronchospasm and loosen mucus, making breathing easier.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Used to manage chronic bronchitis by reducing mucus viscosity and improving airflow.","evidence":"Well-established"},{"condition":"COPD","description":"May be used in COPD to relieve bronchospasm and aid mucus clearance.","evidence":"Moderate"},{"condition":"Productive cough","description":"Helps in loosening thick mucus, making it easier to cough out.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Asthma and other obstructive airway diseases

Also treats: Chronic bronchitis, COPD, Productive cough

📋 Drug Information

Generic Name(s)Bromhexine + Salbutamol
Brand NameAsmatide BR 8 mg/4 mg/200 mg Tablet
ManufacturerSystopic Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic + Bronchodilator
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine exactly as prescribed; do not increase the dose without consulting your doctor.
2
Take it after meals to minimize stomach upset.
3
Monitor your heart rate; if you notice persistent palpitations, contact your doctor.
4
Stay well hydrated to help loosen mucus.
5
Avoid caffeine and alcohol as they may worsen side effects like tremors and rapid heartbeat.
6
If you have asthma, keep your rescue inhaler handy in case of an acute attack.
7
Do not use this medicine for more than 7 days without medical advice.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Wheezing and breathlessness
This medicine is commonly prescribed for these symptoms.
Likely Use
✅
Productive cough with thick mucus
Bromhexine helps loosen mucus.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSalbutamol is well absorbed from the gastrointestinal tract after oral administration. Bromhexine is also absorbed orally. However, oral salbutamol undergoes first-pass metabolism, reducing its bioavailability.
DistributionBoth ingredients are distributed widely in the body. Salbutamol crosses the placenta and is excreted in breast milk. Bromhexine also crosses the blood-brain barrier and placental barrier.
Protein BindingSalbutamol is approximately 10% bound to plasma proteins. Bromhexine's protein binding is not well established.
MetabolismSalbutamol is metabolized in the liver primarily by conjugation to inactive sulfate esters. Bromhexine is metabolized in the liver to active metabolites.
Half-LifeThe elimination half-life of salbutamol is approximately 4-6 hours. Bromhexine's half-life is not well established but is estimated to be around 1-2 hours.
ExcretionSalbutamol and its metabolites are excreted mainly in the urine. Bromhexine is excreted primarily in the urine as metabolites.
BioavailabilityOral salbutamol has a bioavailability of approximately 40% due to first-pass metabolism. Bromhexine's oral bioavailability is not well established.
Onset of ActionSalbutamol's bronchodilator effect begins within 15-30 minutes after oral administration. Bromhexine's mucolytic effect may take a few hours to become noticeable.
Peak Plasma TimePeak plasma concentration of salbutamol after oral administration is reached in about 2-4 hours. Bromhexine's peak time is not well established.
Duration of ActionThe bronchodilator effect of salbutamol lasts for about 4-6 hours. Bromhexine's effect lasts for several hours.

How It Works

This medicine combines two active ingredients with complementary actions. Bromhexine is a mucolytic agent that works by breaking down the structure of mucus, reducing its viscosity and making it easier to expel. Salbutamol is a selective beta-2 adrenergic agonist that relaxes the smooth muscles of the airways, leading to bronchodilation and easier breathing. Together, they help relieve bronchospasm and clear mucus from the respiratory tract.

Mechanism Steps

1
Bromhexine breaks down mucus: Bromhexine reduces the viscosity of mucus by breaking down its molecular structure, making it easier to cough out.
2
Salbutamol relaxes airways: Salbutamol binds to beta-2 receptors in the lungs, causing the smooth muscles around the airways to relax, which widens the airways.
3
Improved airflow and mucus clearance: The combined effect leads to easier breathing and more effective clearance of mucus from the respiratory tract.

💡 How to Take asmatide br 8 mg/4 mg/200 mg tablet

Strength: Tablet containing Bromhexine 8 mg and Salbutamol 4 mg.

1Wash your hands before handling the tablet.
2Take the tablet with a full glass of water.
3Swallow the tablet whole; do not crush or chew.
4Take it after meals to reduce stomach upset.
5Follow the dosage schedule prescribed by your doctor.
6Do not take more than the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally two to three times a day, or as directed by your doctor. The dose may vary depending on the severity of your condition and your response to treatment. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially cardiovascular effects. Use with caution and follow your doctor's advice.
Renal ImpairmentDose adjustment may be needed in patients with severe renal impairment. Consult your doctor.
Hepatic ImpairmentDose adjustment may be needed in patients with severe hepatic impairment. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 3 tablets in 24 hours, unless otherwise directed by your doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine
Limit
May increase tremors and heart rate.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of asmatide br 8 mg/4 mg/200 mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if severe or persistent.
Tremors (Common (5-10%))
Usually decreases with continued use. Avoid caffeine. Consult doctor if bothersome.
Increased heart rate (Common (5-10%))
Monitor your pulse. If it feels too fast or irregular, contact your doctor.
Stomach upset (Common (5-10%))
Take with meals. Avoid spicy foods. Consult doctor if persistent.

🚨 Serious Side Effects

Severe allergic reaction (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, lips, or throat, or difficulty breathing.
Irregular heartbeat (Rare (<0.1%))
Contact your doctor immediately if you feel palpitations, chest pain, or shortness of breath.
Low potassium levels (Rare (<0.1%))
Report muscle weakness, cramps, or fatigue to your doctor. Blood tests may be needed.

⚠️ Rare Side Effects

Bronchospasm
Seek immediate medical help if breathing becomes worse after taking this medicine.
Severe skin reactions
Stop the medicine and seek immediate medical attention if you notice severe rash, blistering, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Tricyclic antidepressants Major
Furosemide Moderate
Corticosteroids Moderate
Digoxin Moderate
Ipratropium Minor
Theophylline Minor
Caffeine Minor
Alcohol Minor

🚨 Major Interactions

  • Beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs)
  • Tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide)
  • Corticosteroids
  • Digoxin

🍷 Alcohol Interaction

Alcohol may increase the risk of drowsiness, dizziness, and rapid heart rate when taken with this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to bromhexine, salbutamol, or any component of the formulation","Severe cardiovascular disease, including severe heart failure and arrhythmias","Uncontrolled hypertension","Severe hyperthyroidism","History of severe allergic reactions to beta-agonists"]

⚠️ Warnings & Precautions

["Use with caution in patients with cardiovascular disorders, including coronary insufficiency, arrhythmias, and hypertension.","May cause hypokalemia; monitor potassium levels in patients at risk.","Use with caution in patients with diabetes mellitus, as salbutamol may increase blood glucose levels.","May cause tremors and nervousness; avoid driving or operating machinery until effects are known.","Not recommended for children under 12 years without medical advice.","Do not exceed the recommended dose; excessive use may lead to serious cardiovascular effects.","Consult your doctor if symptoms persist or worsen after 7 days of treatment."]

🤱 Lactation Safety

Salbutamol is excreted in breast milk. It is generally considered safe for use during breastfeeding, but consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose may cause severe tachycardia, tremors, palpitations, hypokalemia, and hyperglycemia. Seek immediate medical attention. Treatment is supportive and symptomatic, including monitoring of vital signs and electrolyte levels. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more or less than the recommended dose. Swallow the tablet whole with a glass of water, preferably after meals to reduce stomach upset. Do not crush or chew the tablet. If you have heart disease, high blood pressure, diabetes, or thyroid problems, inform your doctor before taking this medicine. Avoid drinking alcohol while taking this medicine, as it can increase drowsiness and heart rate. Do not drive or operate heavy machinery until you know how this medicine affects you. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Keep this medicine out of reach of children. Store it at room temperature, away from direct sunlight and moisture. Do not use it after the expiry date.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to cardiovascular side effects such as tachycardia and arrhythmias. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The benefits and risks should be weighed.

🏥 Post-Surgery Considerations

Consult your doctor before resuming this medicine after surgery, especially if you have had cardiac or respiratory surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with certain anesthetics or medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke.
🥗
Use a humidifier to keep airways moist.
😴
Practice deep breathing exercises.
💧
Stay hydrated to help thin mucus.
🧘
Get adequate rest to support recovery.
🌞
Avoid known allergens and pollutants.

🏋️ Exercise Considerations

Avoid strenuous exercise if you have acute breathing difficulties. Consult your doctor before starting any exercise program. If exercise triggers your symptoms, use your rescue inhaler as prescribed.

🥗 Diet Recommendations

Include plenty of fluids to help loosen mucus.
Eat a balanced diet rich in fruits and vegetables.
Limit caffeine and alcohol.
Avoid spicy foods if they trigger coughing.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tremors, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is generally safe to continue desk work, but take breaks if you feel dizzy.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Your doctor will advise you on whether to stop or adjust the dose.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to tolerance to salbutamol's effects and reduced responsiveness. It may also cause hypokalemia and cardiac effects. Regular monitoring of heart rate, blood pressure, and potassium levels is advised. Use the lowest effective dose for the shortest duration necessary.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Inhaled bronchodilators

Inhaled salbutamol provides targeted relief with fewer systemic side effects.

Evidence: Well-established
Steam inhalation

Helps loosen mucus and soothe airways.

Evidence: Traditional

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information. Consult your doctor regarding vaccinations, especially if you have chronic respiratory disease.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, adjust your dosing schedule gradually as advised by your doctor. Check local customs regulations regarding carrying prescription medicines. Always keep enough supply for the duration of your trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with chronic bronchitis
He was prescribed this medicine for his persistent cough and breathlessness. After taking it regularly for a week, he noticed that his cough became more productive and breathing was easier. He experienced mild tremors initially, which subsided after a few days.
💡 Lesson: Consistent use as prescribed helps improve symptoms, and mild side effects often diminish with time.
👤 A 50-year-old woman with asthma
She used this medicine as an add-on to her inhaler therapy. She found that her episodes of breathlessness reduced, and she could clear mucus more easily. She was advised to monitor her heart rate and report any palpitations.
💡 Lesson: This medicine can be effective when used as part of a comprehensive asthma management plan, but monitoring for side effects is important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Salbutamol starts working within 15-30 minutes, while bromhexine's mucolytic effect may take a few hours. You may notice easier breathing relatively quickly.

Q: Can I take it with other medicines?

A: Inform your doctor about all medicines you take, especially beta-blockers, diuretics, and antidepressants, as they may interact with this medicine.

Q: Is it safe during pregnancy?

A: Consult your doctor. Salbutamol is generally considered safe, but the combination should be used only if clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for asmatide br 8 mg/4 mg/200 mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure asthma permanently.
    Fact: This medicine provides symptomatic relief but does not cure asthma. Asthma management requires a comprehensive plan.
  • Myth: It is safe to take extra doses if symptoms worsen.
    Fact: Taking more than the prescribed dose can cause serious heart and electrolyte problems. Always follow your doctor's advice.

🔄 Alternative Options

Generic Alternatives

  • Bromhexine + Salbutamol tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Bromhexine 8 mg + Salbutamol 4 mg","uses":"Asthma, bronchitis, COPD","notes":"Combination of mucolytic and bronchodilator."},{"medicine":"Salbutamol + Ambroxol","composition":"Salbutamol 4 mg + Ambroxol 30 mg","uses":"Productive cough with bronchospasm","notes":"Ambroxol is a mucolytic similar to bromhexine."}]

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