cetdex syrup
What is cetdex syrup used for?
Alkof Syrup (Cetirizine + Dextromethorphan Hydrobromide) is used to treat RESPIRATORY. It contains Cetirizine (5mg) + Dextromethorphan Hydrobromide (10mg), which Cetirizine: selective H1-receptor antagonist; Dextromethorphan: NMDA receptor an. Always consult your doctor before use. Take as prescribed.
- Generic Name: Cetirizine + Dextromethorphan Hydrobromide
- Manufacturer: Digmedi Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cetdex syrup Uses & Benefits
Allergic rhinitis, cough suppression
Off-label uses: Chronic urticaria, nocturnal cough
๐ Drug Information
| Generic Name(s) | Cetirizine + Dextromethorphan Hydrobromide |
| Brand Name | Alkof Syrup |
| Manufacturer | Digmedi Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Antitussive |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Cetirizine: selective H1-receptor antagonist; Dextromethorphan: NMDA receptor antagonist and sigma-1 agonist
Mechanism Steps
๐ก How to Take cetdex syrup
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cetdex syrup
โ Common Side Effects
- Drowsiness
- Dry mouth
- Fatigue
- Dizziness
- Nausea
๐จ Serious Side Effects
- Respiratory depression
- Serotonin syndrome
- Severe allergic reaction
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Arrhythmias
- Seizures
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Hypertensive crisis, serotonin syndrome |
| CYP2D6 inhibitors | Major | Increased dextromethorphan toxicity |
| CNS depressants | Major | Additive sedation and respiratory depression |
| Alcohol | Moderate | Enhanced sedation and impaired coordination |
| Sedatives | Moderate | Additive CNS depression |
| Anticholinergics | Moderate | Increased anticholinergic effects |
| Cimetidine | Minor | Slight increase in cetirizine levels |
| Ritonavir | Minor | Possible increase in dextromethorphan levels |
๐จ Major Interactions
- MAOIs
- CYP2D6 inhibitors
- CNS depressants
โก Moderate Interactions
- Alcohol
- Sedatives
- Anticholinergics
โน๏ธ Minor Interactions
- Cimetidine
- Ritonavir
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase dextromethorphan levels
๐ท Alcohol Interaction
Increased CNS depression and sedation
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, MAOI use within 14 days, severe hypertension, narrow-angle glaucoma
๐ Monitoring Parameters
Sedation, respiratory rate, blood pressure, liver function
๐คฑ Lactation Safety
Use with caution; small amounts excreted in breast milk
๐ Overdose Management
Supportive care; activated charcoal; consider naloxone for respiratory depression
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Found this to be a helpful product. Good results.
Effective and reliable. Worked as expected.
Found this to be a helpful product. Good results.
Good quality medicine. Satisfied with the outcome.
Effective and reliable. Worked as expected.