artid 75mg capsule sr - Indomethacin (75mg) medicine

Artid 75mg Capsule SR: Comprehensive Medicine Guide

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Indomethacin (75mg)

🏭 Digmedi Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 17, 2026

⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Indomethacin is generally avoided during the third trimester due to risk of premature closure of the ductus arteriosus. Consult your doctor if you are pregnant or planning to become pregnant. 📋 Prescription Required 💊 Generic Available

Medically Reviewed

11 min read

Evidence: Well-established for approved indications.

Reviewed by

SaathiMed Expert Panel | Oct 17, 2026

🩺

Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

Blood in stool or vomit
Severe abdominal pain
Chest pain or difficulty breathing
Severe headache with visual changes
Sudden swelling of face, lips, or throat
Yellowing of skin or eyes
Decreased urine output
Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is artid 75mg capsule sr used for?

This medicine contains Indomethacin 75mg, a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, swelling, and stiffness in conditions like arthritis and gout. It works by reducing inflammation. Take it with food to avoid stomach upset and never crush the capsule.

Generic Name: Indomethacin
Manufacturer: Digmedi Pvt Ltd
Form: Allopathy
Pregnancy Category: Consult doctor
Prescription Required: Yes

🇮🇳 artid 75mg capsule sr के बारे में (Hindi Summary)

उपयोग: यह दवा इंडोमेथासिन 75mg का एक सस्टेन्ड-रिलीज़ कैप्सूल है, जिसका उपयोग सूजन, दर्द और अकड़न को कम करने के लिए किया जाता है। यह गठिया (आर्थराइटिस), गाउट, और अन्य सूजन संबंधी स्थितियों में प्रभावी है। यह दवा शरीर में सूजन पैदा करने वाले पदार्थों को रोककर काम करती है। इसे भोजन के साथ लेना चाहिए ताकि पेट में जलन न हो। कैप्सूल को चबाना या तोड़ना नहीं चाहिए। इस दवा को डॉक्टर की सलाह के बिना न लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट में जलन, दस्त, कब्ज, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, अल्सर, गुर्दे की समस्या, दिल का दौरा, और एलर्जी प्रतिक्रियाएं हो सकती हैं। यदि आपको काला मल, खून की उल्टी, तेज पेट दर्द, सांस लेने में कठिनाई, या चेहरे पर सूजन हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के बताए अनुसार ही लें। इसे भोजन या दूध के साथ लें ताकि पेट में जलन न हो। कैप्सूल को पूरा निगलें, चबाएं नहीं। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको गुर्दे, लीवर, या दिल की बीमारी है, तो डॉक्टर को बताएं। दवा को ठंडी, सूखी जगह पर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 artid 75mg capsule sr Uses & Benefits

[{"condition":"Osteoarthritis","description":"Relieves pain, inflammation" class="semantic-link" title="Medicines for swelling">swelling, and stiffness in joints affected by osteoarthritis, improving mobility and quality of life.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces inflammation and pain in rheumatoid arthritis, helping to maintain joint function.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Alleviates pain and stiffness in the spine and other joints associated with ankylosing spondylitis.","evidence":"Well-established"},{"condition":"Acute gouty arthritis","description":"Provides rapid relief from the severe pain and inflammation of acute gout attacks.","evidence":"Well-established"},{"condition":"Bursitis and tendinitis","description":"Reduces inflammation and pain in conditions affecting the bursae and tendons.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, but not a first-line treatment.","evidence":"Limited"},{"condition":"Patent ductus arteriosus (PDA) in premature infants","description":"Used off-label in neonates to close a patent ductus arteriosus, but this is a specialized use.","evidence":"Well-established in neonates"}]

Primary treatment for: Inflammatory conditions such as arthritis and gout

Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Acute gouty arthritis, Bursitis, Tendinitis

📋 Drug Information

Generic Name(s)	Indomethacin
Brand Name	Artisid 50mg Capsule
Manufacturer	Digmedi Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	PAIN ANALGESICS
Action Class	NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
Route of Administration	Oral
Storage	Store at room temperature (15-30°C) in a cool, dry place away from direct sunlight. Keep in the original container, tightly closed.
Shelf Life	24 months from the date of manufacture.
WHO Guideline	Not established from the available information.
ICMR Guideline	Not established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

Always prescribe the lowest effective dose for the shortest duration.

Advise patients to take the capsule with food or milk to minimize GI upset.

Warn patients not to crush or chew the sustained-release capsule.

Monitor renal function, liver function, and CBC periodically during long-term therapy.

Avoid concomitant use with other NSAIDs or anticoagulants unless necessary.

Educate patients about the signs of GI bleeding and cardiovascular events.

Consider gastroprotective agents for patients at high risk of ulcers.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅

Chronic joint pain

This medicine is commonly prescribed for this.

Likely Use

❌

Fever

This medicine is not a primary fever reducer.

Not Primary

✅

Acute gout attack

This medicine is effective for gout pain.

Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionIndomethacin is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration. The sustained-release formulation may delay absorption slightly but provides prolonged plasma levels. Food may delay absorption but does not significantly affect the extent of absorption.

DistributionIndomethacin is highly bound to plasma proteins and distributes widely into body tissues and fluids, including synovial fluid. It crosses the placenta and is excreted in breast milk.

Protein BindingApproximately 90-99% bound to plasma proteins, primarily albumin.

MetabolismIndomethacin is extensively metabolized in the liver, primarily by conjugation with glucuronic acid and O-demethylation. The metabolites are largely inactive.

Half-LifeThe elimination half-life of indomethacin is approximately 4.5 hours, but it may be prolonged in neonates and patients with renal impairment.

ExcretionIndomethacin and its metabolites are excreted primarily in the urine (about 60%) and feces (about 30%).

BioavailabilityThe oral bioavailability of indomethacin is approximately 100% for immediate-release formulations. The sustained-release form may have slightly reduced bioavailability but is designed to provide prolonged action.

Onset of ActionPain relief typically begins within 30 minutes to 2 hours after oral administration.

Peak Plasma TimePeak plasma concentrations are reached in about 1-2 hours for immediate-release formulations; the sustained-release form may peak later, around 2-4 hours.

Duration of ActionThe analgesic and anti-inflammatory effects last approximately 4-6 hours for immediate-release, while the sustained-release form may provide relief for up to 12 hours.

How It Works

This medicine works by inhibiting the enzyme cyclooxygenase (COX), which is responsible for the production of prostaglandins. Prostaglandins are chemicals that mediate inflammation, pain, and fever. By blocking COX, this medicine reduces the levels of prostaglandins, thereby decreasing inflammation, pain, and swelling. Indomethacin is a non-selective COX inhibitor, meaning it inhibits both COX-1 and COX-2 enzymes. Inhibition of COX-1 can lead to gastrointestinal side effects, while inhibition of COX-2 contributes to its anti-inflammatory effects.

Mechanism Steps

Absorption: Indomethacin is absorbed from the gastrointestinal tract after oral administration.

COX inhibition: Indomethacin binds to and inhibits the cyclooxygenase enzymes (COX-1 and COX-2).

Reduced prostaglandin synthesis: Inhibition of COX leads to decreased production of prostaglandins from arachidonic acid.

Decreased inflammation and pain: Lower prostaglandin levels result in reduced inflammation, pain, and fever.

💡 How to Take artid 75mg capsule sr

Strength: Sustained-release capsule containing 75mg of Indomethacin.

1Swallow the capsule whole with a full glass of water.

2Take with food or milk to reduce stomach upset.

3Do not crush, chew, or break the capsule.

4Take at the same time each day to maintain consistent levels.

5If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult Dosage	The usual adult dose of this medicine is 75mg once or twice daily, depending on the condition being treated. For acute gout, a higher initial dose may be used, followed by a lower maintenance dose. The sustained-release capsule should be swallowed whole with a full glass of water, with food or milk to reduce stomach upset. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the maximum recommended dose.
Pediatric Dosage	Pediatric dosing is not established from available information. Consult a pediatrician.
Elderly Dosage	Elderly patients are at increased risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration possible. Dose must be individualized by a qualified clinician.
Renal Impairment	Use with caution in patients with renal impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing.
Hepatic Impairment	Use with caution in patients with hepatic impairment. Dose reduction may be necessary. Consult a doctor for individualized dosing.
Maximum Daily Dose	The maximum recommended daily dose is 150mg, but the usual maximum is 75mg twice daily. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food

Take with meals

Reduces stomach upset.

Alcohol

Avoid

Increases risk of gastrointestinal bleeding.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed

→ Take the missed dose as soon as you remember.

💡 Continue with the regular schedule.

📌 More than half the dosing interval has passed

→ Skip the missed dose.

💡 Do not double dose to catch up.

⚠️ Side Effects of artid 75mg capsule sr

✅ Common Side Effects

Nausea (Common (10-20%))

Take with food or milk to reduce nausea. If it persists, consult your doctor.

Heartburn (Common (10-20%))

Avoid lying down immediately after taking the medicine. Take with food. If severe, contact your doctor.

Stomach pain (Common (10-20%))

Take with food. If pain is severe or persistent, seek medical advice.

Headache (Common (5-10%))

Usually resolves on its own. If persistent or severe, consult your doctor.

Dizziness (Common (5-10%))

Avoid driving or operating machinery until you know how this medicine affects you.

🚨 Serious Side Effects

Gastrointestinal bleeding (Uncommon (0.1-1%))

Seek immediate medical attention if you notice black or tarry stools, vomiting blood, or severe abdominal pain.

Peptic ulcer (Uncommon (0.1-1%))

Report persistent stomach pain or indigestion to your doctor immediately.

Kidney impairment (Rare (<0.1%))

Contact your doctor if you experience decreased urine output, swelling in legs, or fatigue.

Heart attack or stroke (Rare (<0.1%))

Seek emergency help if you have chest pain, shortness of breath, or sudden weakness on one side of the body.

Severe allergic reaction (Rare (<0.1%))

Call emergency services if you experience swelling of face, lips, or throat, or difficulty breathing.

⚠️ Rare Side Effects

Liver damage

Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor immediately.

Blood disorders

Report unusual bleeding or bruising, fever, or sore throat to your doctor.

Severe skin reactions

Seek immediate medical attention if you develop a rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug	Severity	Effect
Warfarin	Major
Aspirin	Major
Ibuprofen	Major
Corticosteroids	Major
Lithium	Major
Methotrexate	Major
ACE inhibitors	Moderate
Diuretics	Moderate
Cyclosporine	Moderate
Digoxin	Moderate

🚨 Major Interactions

Warfarin
Other NSAIDs (e.g., aspirin, ibuprofen)
Corticosteroids
Lithium
Methotrexate

⚡ Moderate Interactions

ACE inhibitors and ARBs
Diuretics
Beta-blockers
Cyclosporine
Digoxin

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol can increase the risk of stomach bleeding and ulcers, and may worsen dizziness or drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to indomethacin or other NSAIDs","History of asthma, urticaria, or allergic reaction to aspirin or NSAIDs","Active peptic ulcer or history of recurrent ulcers","Severe heart failure","Severe kidney impairment","Severe liver impairment","Third trimester of pregnancy","Coronary artery bypass graft (CABG) surgery"]

⚠️ Warnings & Precautions

["Take with food or milk to reduce stomach upset.","Do not crush, chew, or break the sustained-release capsule.","Avoid alcohol while taking this medicine.","Use with caution in elderly patients due to increased risk of side effects.","Monitor kidney and liver function during long-term use.","May cause dizziness or drowsiness; avoid driving if affected.","Do not use for more than 10 days for pain unless directed by a doctor.","Inform your doctor if you have a history of heart disease, high blood pressure, or diabetes."]

🤱 Lactation Safety

Indomethacin is excreted in breast milk. Limited data suggest it may be safe during breastfeeding, but consult your doctor before use.

💊 Overdose Management

Overdose symptoms may include severe nausea, vomiting, stomach pain, drowsiness, confusion, and gastrointestinal bleeding. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Always take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take it with food or milk to reduce stomach upset. Swallow the capsule whole; do not crush, chew, or break it, as this can release the entire dose at once and increase the risk of side effects. Avoid alcohol while taking this medicine, as it can increase the risk of stomach bleeding. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, high blood pressure, or asthma. Also, tell your doctor about all other medications you are taking, especially blood thinners, other NSAIDs, corticosteroids, or antidepressants. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not drive or operate heavy machinery if you experience dizziness or drowsiness. Regular monitoring of kidney function, liver function, and blood counts may be required during long-term therapy. Keep this medicine out of reach of children and store it in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose and monitor closely.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning to become pregnant. This medicine is generally avoided during the third trimester due to risk of premature closure of the ductus arteriosus.

🏥 Post-Surgery Considerations

This medicine should not be used for peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery. Consult your surgeon before using it after any surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may increase the risk of bleeding during dental procedures.

💚 Lifestyle Tips for Better Results

🏃

Maintain a healthy weight to reduce joint stress.

🥗

Regular low-impact exercise like swimming.

😴

Practice good posture.

💧

Include anti-inflammatory foods in your diet.

🧘

Get adequate sleep.

🌞

Avoid smoking and limit alcohol.

🏋️ Exercise Considerations

Avoid high-impact exercises that may worsen joint pain. Consult your doctor or physical therapist for an exercise plan tailored to your condition.

🥗 Diet Recommendations

Include omega-3 rich foods

Reduce processed food intake

Stay well hydrated

Limit alcohol and caffeine

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects, seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, and cardiovascular events. Regular monitoring of kidney function, liver function, and blood counts is recommended. Use the lowest effective dose for the shortest duration possible.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established

Weight loss

Reduces stress on joints and improves symptoms.

Evidence: Well-established

Acupuncture

May help with pain relief in some patients.

Evidence: Moderate

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with chronic knee osteoarthritis

He was prescribed this medicine for knee pain. He took it with food as advised and noticed significant pain relief within a week. He also started physical therapy and lost some weight, which further improved his mobility.

💡 Lesson: Taking the medicine with food and combining it with lifestyle changes enhances outcomes.

👤 A 45-year-old woman with acute gout attack

She experienced severe pain in her big toe. Her doctor prescribed this medicine. She took it as directed and felt relief within a few hours. She was advised to avoid alcohol and drink plenty of water.

💡 Lesson: Prompt use of this medicine during a gout attack can provide rapid relief, but lifestyle modifications are crucial.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Pain relief typically begins within 30 minutes to 2 hours after taking the medicine.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular schedule.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

Can I take this medicine long-term?
Will it affect my kidney function?
Can I drive after taking this medicine?
Does it interact with my blood pressure medicine?
What if I miss a dose?
Can I drink alcohol while taking this?

🔄 Substitutes for artid 75mg capsule sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food or milk to reduce stomach upset.
Myth: It is safe to crush or chew the capsule for faster relief.
Fact: The capsule must be swallowed whole; crushing or chewing can release the entire dose at once and increase side effects.
Myth: This medicine is safe to use for any type of pain.
Fact: It is specifically for inflammatory conditions and should only be used as prescribed.

🔄 Alternative Options

Generic Alternatives

Indomethacin 75mg sustained-release capsules

Brand Alternatives

Artid 75mg capsule SR

📊 Comparison with Similar Medicines

[{"medicine":"Indomethacin","class":"NSAID","half_life":"4.5 hours","common_uses":"Arthritis, gout","notes":"Sustained-release form available."},{"medicine":"Diclofenac","class":"NSAID","half_life":"1-2 hours","common_uses":"Arthritis, pain","notes":"Also available in topical forms."},{"medicine":"Ibuprofen","class":"NSAID","half_life":"2 hours","common_uses":"Pain, fever, inflammation","notes":"Available over-the-counter."}]

Artid 75mg Capsule SR: Comprehensive Medicine Guide

When to Call Your Doctor IMMEDIATELY

What is artid 75mg capsule sr used for?

🇮🇳 artid 75mg capsule sr के बारे में (Hindi Summary)

💊 artid 75mg capsule sr Uses & Benefits

📋 Drug Information

👨‍⚕️ Doctor's Practical Tips

🔍 Is This Medicine Right for Your Symptom?

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take artid 75mg capsule sr

Dosage Information

Dosage Timeline

🍽️ Food Timing Guide

⏰ What to Do If You Miss a Dose

⚠️ Side Effects of artid 75mg capsule sr

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

🍷 Alcohol Interaction

🔎 Check Your Other Medicines

🛡️ Safety & Warnings

🚫 Contraindications

⚠️ Warnings & Precautions

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

Additional Safety Advice

👴 Special Considerations for Elderly

💡 For Patients Above 65

🤰 Pregnancy Planning (TTC)

🏥 Post-Surgery Considerations

🦷 Dental Procedures

💚 Lifestyle Tips for Better Results

🏋️ Exercise Considerations

🥗 Diet Recommendations

💼 Impact on Daily Work & Life

🛑 When to Stop This Medicine

📅 Long-Term Use Effects

🌿 Non-Medicine Approaches

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

📦 Storage Guide

✅ DO

❌ DON'T

✅ DO

❌ DON'T

✅ DO

❌ DON'T

✈️ Traveling with This Medicine

💰 Cost Analysis & Savings

👥 Real Patient Stories

💬 Questions Patients Often Ask

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

🔄 Substitutes for artid 75mg capsule sr

🛑 Myths vs. Facts

🔄 Alternative Options

Generic Alternatives

Brand Alternatives

📊 Comparison with Similar Medicines

😊 Was this information helpful?

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