Mykast Plus 10mg/5mg/200mg Tablet SR: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or severe asthma attack
- Swelling of face, lips, or throat
- Severe skin rash with blistering
- Rapid or irregular heartbeat
- Yellowing of skin or eyes
- Severe abdominal pain
- Seizures
If experiencing severe symptoms, call emergency services immediately.
What is Airent LM Tablet SR used for?
This medicine is a combination of Montelukast, Levocetirizine, and Acebrophylline used to treat asthma and allergic rhinitis. It works by reducing inflammation, blocking histamine, and relaxing airways. It is not for acute attacks.
- Generic Name: Montelukast (10mg) + Levocetirizine (5mg) + Acebrophylline (200mg)
- Manufacturer: Ernst Pharmacia
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Airent LM Tablet SR के बारे में (Hindi Summary)
उपयोग: यह दवा मोंटेलुकास्ट, लेवोसेटिरिज़िन और एसीब्रोफिलिन का संयोजन है, जिसका उपयोग अस्थमा और एलर्जिक राइनाइटिस के इलाज के लिए किया जाता है। यह सांस की नली में सूजन कम करती है, एलर्जी के लक्षणों को कम करती है और सांस लेने में आसानी प्रदान करती है। यह दवा तीव्र अस्थमा हमले के लिए नहीं है।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, नींद आना, मुँह सूखना, जी मिचलाना और पेट में असहजता शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, धड़कन बढ़ना, या मूड में बदलाव हो सकते हैं। कोई भी असामान्य लक्षण होने पर डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। गोली को चबाएं या तोड़ें नहीं। इसे पानी के साथ निगलें। दवा लेने के बाद नींद आ सकती है, इसलिए वाहन चलाने से बचें। शराब का सेवन न करें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर से सलाह लें। तीव्र अस्थमा हमले के लिए इसका उपयोग न करें।
💊 Airent LM Tablet SR Uses & Benefits
[{"condition":"Bronchial asthma","description":"Used for the maintenance treatment of asthma in adults and adolescents to reduce the frequency of attacks and improve lung function.","evidence":"Well-established"},{"condition":"Allergic rhinitis","description":"Helps relieve symptoms such as sneezing, runny nose, itching, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Exercise-induced bronchoconstriction","description":"May help prevent narrowing of the airways triggered by physical activity.","evidence":"Moderate"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Sometimes used as an add-on therapy to improve symptoms and reduce exacerbations, though evidence is less robust.","evidence":"Limited"}]
Off-label uses: [{"condition":"Urticaria (hives)","description":"Levocetirizine component may help relieve itching and hives, but the combination is not specifically approved for this.","evidence":"Limited"},{"condition":"Sleep-related breathing disorders","description":"Montelukast has been studied in sleep apnea, but evidence is insufficient for routine use.","evidence":"Limited"}]
Primary treatment for: Bronchial asthma
Also treats: Allergic rhinitis, Exercise-induced bronchoconstriction, COPD
📋 Drug Information
| Generic Name(s) | Montelukast (10mg) + Levocetirizine (5mg) + Acebrophylline (200mg) |
| Brand Name | Airent LM Tablet SR |
| Manufacturer | Ernst Pharmacia |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines three active ingredients with complementary mechanisms. Montelukast selectively blocks the cysteinyl leukotriene receptor type 1 (CysLT1) in the airways, preventing leukotriene-mediated bronchoconstriction, mucus secretion, and inflammation. Levocetirizine, the active enantiomer of cetirizine, is a potent selective antagonist of the H1 histamine receptor, reducing allergic responses such as vasodilation, itching, and sneezing. Acebrophylline is a xanthine derivative that inhibits phosphodiesterase enzymes, leading to increased cyclic AMP levels, which relaxes bronchial smooth muscle and reduces inflammation. Additionally, acebrophylline has mucolytic properties, helping to thin mucus and ease its clearance from the airways. Together, these actions provide bronchodilation, anti-inflammatory, and antihistamine effects, making the combination useful for chronic respiratory conditions.
Mechanism Steps
💡 How to Take Airent LM Tablet SR
Strength: Sustained-release tablet containing Montelukast 10mg, Levocetirizine 5mg, and Acebrophylline 200mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet once daily, preferably in the evening. However, dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to side effects such as drowsiness and cardiac effects. Dose adjustment may be needed based on renal and hepatic function. Consult a doctor. |
| Renal Impairment | Levocetirizine dose may need adjustment in renal impairment. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in hepatic impairment. Montelukast and acebrophylline may require dose adjustment. Consult a doctor. |
| Maximum Daily Dose | One tablet per day, unless otherwise prescribed by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Airent LM Tablet SR
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Benzodiazepines | Major | |
| Rifampicin | Moderate | |
| Theophylline | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- CNS depressants (e.g., benzodiazepines, opioids)
- Alcohol
⚡ Moderate Interactions
- Rifampicin
- Theophylline
🍷 Alcohol Interaction
Alcohol can increase drowsiness and impair motor skills when taken with this medicine. It is advisable to avoid alcohol completely while on this medication.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to any component of this medicine","Severe hepatic impairment","Severe renal impairment (for levocetirizine component)","Acute asthma attack (not for rescue therapy)"]
⚠️ Warnings & Precautions
["Do not use for acute bronchospasm; keep rescue inhaler available.","May cause drowsiness; avoid driving or operating machinery until effects are known.","Avoid alcohol and other CNS depressants.","Use with caution in patients with liver or kidney disease.","Montelukast may cause neuropsychiatric events; monitor mood changes.","Acebrophylline may cause cardiac stimulation; use with caution in heart disease.","Do not crush or chew sustained-release tablets."]
🤱 Lactation Safety
Montelukast and levocetirizine are excreted in breast milk in small amounts. Acebrophylline excretion is unknown. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe drowsiness, palpitations, nausea, or seizures. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the sustained-release tablet; swallow it whole with a glass of water. It can be taken with or without food, but taking it with food may reduce stomach upset. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it may cause drowsiness. Do not consume alcohol while taking this medicine because it can increase drowsiness and other side effects. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not use this medicine for an acute asthma attack; always keep a rescue inhaler available. Keep all follow-up appointments and inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements. Store this medicine at room temperature away from moisture and heat. Do not share this medicine with others, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to drowsiness and cardiac effects. Dose adjustment may be needed based on renal and hepatic function. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
Consult your doctor if you are planning pregnancy or are pregnant. The safety of acebrophylline during pregnancy is not well established.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist about this medicine before surgery. It may interact with other medications used during surgery.
🦷 Dental Procedures
Inform your dentist about this medicine before any dental procedure. It may cause dry mouth, which can affect oral health.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Exercise may trigger asthma symptoms. Use your rescue inhaler as prescribed before exercise if advised. Warm up gradually and avoid exercising in cold, dry air.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, affecting your ability to drive or operate machinery. It is advisable to avoid such activities until you know how it affects you. Inform your employer if your job involves safety-sensitive tasks.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects, contact your doctor immediately for guidance.
📅 Long-Term Use Effects
Long-term use may require periodic monitoring of liver and kidney function. Montelukast has been associated with neuropsychiatric effects, and acebrophylline with cardiac effects. Regular follow-up with your doctor is recommended.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Reducing exposure to allergens can help control symptoms.
Evidence: Well-establishedAllergy shots may provide long-term relief for allergic rhinitis.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are established. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Some effects may be felt within hours, but full benefits for asthma control may take several days to weeks.
A: Consult your doctor before taking additional antihistamines, as additive effects may occur.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can be used for immediate relief of asthma attacks.
Fact: It is a maintenance medicine and not for acute attacks. Always use a rescue inhaler for sudden symptoms. - Myth: It is safe to drive after taking this medicine.
Fact: It may cause drowsiness. Avoid driving until you know how it affects you.
🔄 Alternative Options
Generic Alternatives
- Montelukast + Levocetirizine + Acebrophylline combination generics