cefro 500mg tablet - Cefuroxime (500mg) medicine

cefro 500mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Mefro Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is cefro 500mg tablet used for?

Cefro 500mg Tablet (Cefuroxime) is used to treat GASTRO INTESTINAL. It contains Cefuroxime (500mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Cefuroxime
  • Manufacturer: Mefro Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š cefro 500mg tablet Uses & Benefits

Upper and lower respiratory tract infections, urinary tract infections, skin and soft tissue infections, otitis media, sinusitis, Lyme disease, gonorrhea

Off-label uses: Prophylaxis in surgery, Empiric therapy for febrile neutropenia (in combination)

๐Ÿ“‹ Drug Information

Generic Name(s)Cefuroxime
Brand NameCefro 500mg Tablet
ManufacturerMefro Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassQuinolones/ Fluroquinolones
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed after oral administration
DistributionDistributes widely into body tissues and fluids, including pleural fluid, synovial fluid, bone, and CSF (when meninges inflamed)
Protein Binding33-50%
MetabolismNot significantly metabolized
Half-Life1-2 hours
ExcretionRenal excretion (80-90% unchanged in urine)
BioavailabilityApproximately 50-70% (oral)
Onset of ActionRapid (within 30-60 minutes)
Peak Plasma Time2-3 hours after oral dose
Duration of Action8-12 hours

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting peptidoglycan cross-linking

Mechanism Steps

1Cefuroxime binds to penicillin-binding proteins (PBPs) on bacterial cell wall
2Inhibits transpeptidase activity, preventing peptidoglycan cross-linking
3Disrupts cell wall synthesis, leading to osmotic lysis and bacterial death

๐Ÿ’ก How to Take cefro 500mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cefro 500mg tablet

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Injection site reactions (if IV)

๐Ÿšจ Serious Side Effects

  • Severe hypersensitivity reactions (anaphylaxis)
  • Clostridioides difficile infection
  • Stevens-Johnson syndrome
  • Seizures (high doses)

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Agranulocytosis
  • Thrombocytopenia
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Probenecid Major Decreased renal excretion of cefuroxime, increased plasma levels
Live typhoid vaccine Major Reduced vaccine efficacy
BCG vaccine Major Reduced vaccine efficacy
Loop diuretics Moderate Increased risk of nephrotoxicity
Aminoglycosides Moderate Additive nephrotoxicity
Oral contraceptives Moderate Reduced contraceptive efficacy
Antacids Minor Reduced absorption of cefuroxime
H2 blockers Minor Reduced absorption of cefuroxime
Proton pump inhibitors Minor Reduced absorption of cefuroxime

๐Ÿšจ Major Interactions

  • Warfarin
  • Probenecid
  • Live typhoid vaccine
  • BCG vaccine

โšก Moderate Interactions

  • Loop diuretics
  • Aminoglycosides
  • Oral contraceptives

โ„น๏ธ Minor Interactions

  • Antacids
  • H2 blockers
  • Proton pump inhibitors

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but not significantly affect extent; take with food to reduce GI upset

๐Ÿท Alcohol Interaction

No known interaction; moderate consumption unlikely to cause adverse effects

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to cephalosporins or penicillins; history of severe immediate hypersensitivity reaction to beta-lactams

๐Ÿ“Š Monitoring Parameters

Renal function (especially in elderly or with high doses), signs of superinfection, hypersensitivity reactions

๐Ÿคฑ Lactation Safety

Excreted in breast milk in small amounts; generally considered compatible with breastfeeding

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may enhance elimination

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose and resume regular schedule; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cefro 500mg tablet

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Alternative brands with exact same active ingredient (Cefuroxime (500mg)):

Medical Note: Always consult your doctor before switching medications.

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