ali m 500mg tablet - Complete Medicine Information | SaathiMed

ali m 500mg tablet - Uses, Price, Side Effects & Substitutes

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Metformin (500mg) (Click to see all medicines with same salt)
🏭 Mefro Pharmaceuticals Pvt Ltd Verified 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
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By SaathiMed Expert Medical Panel
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💊 What is ali m 500mg tablet used for?

Ali M 500mg Tablet (Metformin) is used to treat Type 2 diabetes mellitus. It contains Metformin (500mg), which Decreases hepatic glucose production, decreases intestinal absorption of glucose. Always consult your doctor before use. Take as prescribed.
💊 Generic Name
Metformin
🏭 Manufacturer
Mefro Pharmaceuticals Pvt Ltd
📦 Form
Allopathy
🤰 Pregnancy Category
Category A
Uses Price Substitute Side Effects

🇮🇳 ali m 500mg tablet के बारे में संक्षिप्त जानकारी

ali m 500mg tablet का उपयोग मुख्य रूप से anti diabetic और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Metformin (500mg) मौजूद है।

ali m 500mg tablet के फायदे ali m 500mg tablet के नुकसान ali m 500mg tablet की कीमत
💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

📋 Complete Drug Information

Generic Name(s)Metformin
Brand NameAli M 500mg Tablet
ManufacturerMefro Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI DIABETIC
Action ClassBiguanides
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F); protect from light and moisture.

🔬 Pharmacology

Pharmacokinetics

AbsorptionAbsorbed mainly from the small intestine; oral bioavailability 50-60%.
DistributionDistributes into erythrocytes; volume of distribution 654 L.
Protein BindingNegligible (<5%)
MetabolismNot metabolized; excreted unchanged in urine.
Half-Life6.2 hours
ExcretionRenal (90% unchanged)
Bioavailability50-60%
Onset of Action2-3 hours
Peak Plasma Time2-3 hours
Duration of Action8-12 hours

Mechanism of Action

Decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.

Step-by-Step Mechanism

1 Activation of AMPK in hepatocytes
2 Inhibition of gluconeogenesis and glycogenolysis
3 Reduction of hepatic glucose output
4 Increased insulin sensitivity in muscle and adipose tissue
5 Decreased intestinal glucose absorption

💡 How to take ali m 500mg tablet

Prescribed Dosage: Follow your doctor's prescription exactly.
  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose.
  • ✅ Complete the full course of medication.
  • ✅ Store at 20-25°C (68-77°F); protect from light and moisture.

⚠️ Side Effects of ali m 500mg tablet

✅ Common Side Effects

  • Nausea
  • Diarrhea
  • Abdominal discomfort
  • Metallic taste
  • Loss of appetite

🚨 Serious Side Effects

  • Lactic acidosis
  • Vitamin B12 deficiency
  • Hypoglycemia (when combined with other agents)

⚠️ Rare Side Effects

  • Hepatitis
  • Pancreatitis
  • Cutaneous reactions
Important: Consult your doctor if you experience any unusual symptoms or severe side effects.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Iodinated contrast media Major Increased risk of lactic acidosis; discontinue metformin before procedure.
Alcohol Major Increased risk of lactic acidosis.
Cimetidine Moderate Reduced renal elimination of metformin.
Furosemide Moderate Increased metformin plasma concentration.
Nifedipine Moderate Increased metformin absorption.
Digoxin Minor Slight increase in digoxin levels.
Warfarin Minor Slight decrease in INR.

🚨 Major Interactions

  • Iodinated contrast media
  • Alcohol intoxication

⚡ Moderate Interactions

  • Cimetidine
  • Furosemide
  • Nifedipine

🍽️ Food Interactions

Alcohol, High-fat meals may reduce absorption

🍷 Alcohol Interaction

Increased risk of lactic acidosis

🛡️ Safety & Warnings

Pregnancy
Category A
Liver Risk
Low
Kidney Risk
Low
Heart Risk
Low

🚫 Contraindications

Renal impairment (eGFR <30 mL/min), acute or chronic metabolic acidosis, hypersensitivity, severe hepatic impairment, acute heart failure, recent myocardial infarction, sepsis.

📊 Monitoring Parameters

Blood glucose, HbA1c, renal function (eGFR), vitamin B12 levels annually.

🤱 Lactation Safety

Excreted in breast milk; caution advised.

💊 Overdose

Supportive care; hemodialysis may remove metformin.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

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