calnif retard 20mg tablet - Uses, Price, Side Effects & Substitutes
What is calnif retard 20mg tablet used for?
Angiblock 5mg Capsule (Nifedipine) is used to treat CARDIAC. It contains Nifedipine (20mg), which Inhibits calcium ion influx across cardiac and smooth muscle cells, leading to v. Always consult your doctor before use. Take as prescribed.
- Generic Name: Nifedipine
- Manufacturer: Cadila Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ calnif retard 20mg tablet Uses & Benefits
Hypertension, chronic stable angina, vasospastic angina (Prinzmetal's angina), Raynaud's phenomenon
Off-label uses: Preterm labor (tocolysis), high-altitude pulmonary edema, anal fissures (topical)
๐ Drug Information
| Generic Name(s) | Nifedipine |
| Brand Name | Angiblock 5mg Capsule |
| Manufacturer | Cadila Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Calcium channel blockers- Dihydropyridines (DHP) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits calcium ion influx across cardiac and smooth muscle cells, leading to vasodilation and reduced myocardial oxygen demand
Mechanism Steps
๐ก How to Take calnif retard 20mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of calnif retard 20mg tablet
โ Common Side Effects
- Peripheral edema
- Headache
- Dizziness
- Flushing
- Palpitations
- Nausea
- Constipation
๐จ Serious Side Effects
- Severe hypotension
- Myocardial infarction
- Heart failure exacerbation
- Arrhythmias
- Stevens-Johnson syndrome
- Gingival hyperplasia
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Agranulocytosis
- Leukopenia
- Gynecomastia
- Photosensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| CYP3A4 inhibitors (e.g., ketoconazole) | Major | Increased nifedipine levels, risk of toxicity |
| CYP3A4 inducers (e.g., rifampin) | Major | Decreased nifedipine efficacy |
| Beta-blockers | Major | Increased risk of heart failure, hypotension |
| Digoxin | Major | Increased digoxin levels, risk of toxicity |
| Grapefruit juice | Moderate | Increased nifedipine bioavailability |
| Cimetidine | Moderate | Increased nifedipine levels |
๐จ Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- CYP3A4 inducers (e.g., rifampin, phenytoin)
- Beta-blockers
- Digoxin
- Magnesium sulfate (IV)
โก Moderate Interactions
- Antihypertensives
- Cimetidine
- Grapefruit juice
- Quinidine
- Theophylline
โน๏ธ Minor Interactions
- Antacids
- Calcium supplements
- Vitamin D
๐ฝ๏ธ Food Interactions
Grapefruit juice increases bioavailability; avoid concurrent use
๐ท Alcohol Interaction
May enhance hypotensive effect; avoid excessive alcohol
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to nifedipine, cardiogenic shock, severe aortic stenosis, unstable angina (except under special circumstances), within 4 weeks of myocardial infarction
๐ Monitoring Parameters
Blood pressure, heart rate, ECG, signs of peripheral edema, liver function tests
๐คฑ Lactation Safety
Excreted in breast milk; use with caution, monitor infant for hypotension
๐ Overdose Management
Activated charcoal, gastric lavage, IV fluids, calcium gluconate or calcium chloride, vasopressors for hypotension, atropine for bradycardia
โฐ Missed Dose
Take as soon as remembered unless close to next dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for calnif retard 20mg tablet
View AllAlternative brands with exact same active ingredient (Nifedipine (20mg)):
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niferil retard 20mg tabletUSV Ltd โน7.50 2.6% COSTLIER
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angiblock retard 20mg tabletAlkem Laboratories Ltd โน7.97 9% COSTLIER
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cardipin 20mg tabletIntas Pharmaceuticals Ltd โน9.94 36% COSTLIER
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n-dip 20mg tabletTaurus Laboratories Pvt Ltd โน10.22 39.8% COSTLIER
-
nepin 20mg tablet srLincoln Pharmaceuticals Ltd โน11.25 53.9% COSTLIER
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Finidin 20mg TabletIndamed Pharmaceuticals Pvt Ltd โน11.63 59.1% COSTLIER
-
calbloc 20mg tabletTorrent Pharmaceuticals Ltd โน14.75 101.8% COSTLIER
-
niferite retard 20mg tabletMHS Pharmaceuticals Pvt Ltd โน15.00 105.2% COSTLIER
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nifcard 20mg tablet srIntra Labs India Pvt Ltd โน17.81 143.6% COSTLIER
-
angifine 20mg tablet srInvision Medi Sciences Pvt Ltd โน18.00 146.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.