calnif retard 20mg tablet
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
What is calnif retard 20mg tablet used for?
This medicine contains Nifedipine (20mg) and is used to treat CARDIAC. Inhibits calcium ion influx across cardiac and smooth muscle cells, leading to vasodilation and redu. Always consult your doctor before use.
- Generic Name: Nifedipine
- Manufacturer: Cadila Pharmaceuticals Ltd
- Form: Allopathy
- Pregnancy Category: Category A
- Prescription Required: Yes
💊 calnif retard 20mg tablet Uses & Benefits
Hypertension, chronic stable angina, vasospastic angina (Prinzmetal's angina), Raynaud's phenomenon
Off-label uses: Preterm labor (tocolysis), high-altitude pulmonary edema, anal fissures (topical)
📋 Drug Information
| Generic Name(s) | Nifedipine |
| Brand Name | Angiblock 5mg Capsule |
| Manufacturer | Cadila Pharmaceuticals Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Calcium channel blockers- Dihydropyridines (DHP) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C), protect from light and moisture |
| Shelf Life | As per manufacturer |
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Inhibits calcium ion influx across cardiac and smooth muscle cells, leading to vasodilation and reduced myocardial oxygen demand
Mechanism Steps
💡 How to Take calnif retard 20mg tablet
Follow your doctor's prescription exactly.
⚠️ Side Effects of calnif retard 20mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| CYP3A4 inhibitors (e.g., ketoconazole) | Major | Increased nifedipine levels, risk of toxicity |
| CYP3A4 inducers (e.g., rifampin) | Major | Decreased nifedipine efficacy |
| Beta-blockers | Major | Increased risk of heart failure, hypotension |
| Digoxin | Major | Increased digoxin levels, risk of toxicity |
| Grapefruit juice | Moderate | Increased nifedipine bioavailability |
| Cimetidine | Moderate | Increased nifedipine levels |
🚨 Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- CYP3A4 inducers (e.g., rifampin, phenytoin)
- Beta-blockers
- Digoxin
- Magnesium sulfate (IV)
⚡ Moderate Interactions
- Antihypertensives
- Cimetidine
- Grapefruit juice
- Quinidine
- Theophylline
🍷 Alcohol Interaction
May enhance hypotensive effect; avoid excessive alcohol
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity to nifedipine, cardiogenic shock, severe aortic stenosis, unstable angina (except under special circumstances), within 4 weeks of myocardial infarction
🤱 Lactation Safety
Excreted in breast milk; use with caution, monitor infant for hypotension
💊 Overdose Management
Activated charcoal, gastric lavage, IV fluids, calcium gluconate or calcium chloride, vasopressors for hypotension, atropine for bradycardia
⏰ Missed Dose
Take as soon as remembered unless close to next dose; do not double dose
🔄 Substitutes for calnif retard 20mg tablet
View AllAlternative brands with exact same active ingredient:
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niferil retard 20mg tabletUSV Ltd ₹7.50 2.6% COSTLIER
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angiblock retard 20mg tabletAlkem Laboratories Ltd ₹7.97 9% COSTLIER
-
cardipin 20mg tabletIntas Pharmaceuticals Ltd ₹9.94 36% COSTLIER
-
n-dip 20mg tabletTaurus Laboratories Pvt Ltd ₹10.22 39.8% COSTLIER
-
nepin 20mg tablet srLincoln Pharmaceuticals Ltd ₹11.25 53.9% COSTLIER
Medical Note: Always consult your doctor before switching medications.