Angifine 20mg Tablet SR: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe chest pain or worsening angina
- Fainting or severe dizziness
- Shortness of breath or difficulty breathing
- Swelling of face, lips, tongue, or throat
- Yellowing of skin or eyes
- Unusual bleeding or bruising
- Rapid or irregular heartbeat
- Severe headache with visual changes
If experiencing severe symptoms, call emergency services immediately.
What is n-dip 20mg tablet used for?
This medicine contains nifedipine, a calcium channel blocker used to treat high blood pressure and prevent angina. It works by relaxing blood vessels, which lowers blood pressure and improves blood flow to the heart. It is taken orally once daily as a sustained-release tablet.
- Generic Name: Nifedipine (20mg)
- Manufacturer: Taurus Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 n-dip 20mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा निफेडिपिन 20 मिलीग्राम का एक सस्टेन्ड-रिलीज़ टैबलेट है, जिसका उपयोग मुख्य रूप से उच्च रक्तचाप (हाई ब्लड प्रेशर) को नियंत्रित करने और एनजाइना (सीने में दर्द) को रोकने के लिए किया जाता है। यह रक्त वाहिकाओं को आराम देकर उन्हें चौड़ा करती है, जिससे रक्त का प्रवाह आसान हो जाता है और हृदय पर दबाव कम होता है। यह दवा हृदय को ऑक्सीजन की आपूर्ति बढ़ाने में भी मदद करती है। इसे डॉक्टर की सलाह के अनुसार ही लेना चाहिए।
साइड इफेक्ट्स: इस दवा के कुछ सामान्य दुष्प्रभाव हो सकते हैं जैसे सिरदर्द, चेहरे पर गर्मी लगना, चक्कर आना, और टखनों या पैरों में सूजन। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी धड़कन तेज होना, मतली या कब्ज भी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको सीने में दर्द, सांस लेने में कठिनाई, या गंभीर चक्कर आएं तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। इसे डॉक्टर के बताए अनुसार ही लें, आमतौर पर दिन में एक बार। टैबलेट को पानी के साथ पूरा निगलें, चबाएं या तोड़ें नहीं। इस दवा के साथ ग्रेपफ्रूट जूस न पिएं। शराब का सेवन न करें या सीमित करें। यदि आपको चक्कर आते हैं तो गाड़ी चलाने से बचें। दवा को अचानक बंद न करें। इसे कमरे के तापमान पर, धूप और नमी से दूर, बच्चों की पहुंच से बाहर रखें।
💊 n-dip 20mg tablet Uses & Benefits
[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure by relaxing blood vessels, which reduces the force against which the heart must pump.","evidence":"Well-established"},{"condition":"Chronic stable angina","description":"This medicine helps to prevent chest pain by improving blood flow to the heart muscle and reducing the heart's workload.","evidence":"Well-established"},{"condition":"Vasospastic angina (Prinzmetal's angina)","description":"This medicine is effective in preventing coronary artery spasms that cause chest pain at rest.","evidence":"Well-established"},{"condition":"Raynaud's phenomenon","description":"This medicine may be used to reduce the frequency and severity of attacks in some patients with Raynaud's phenomenon.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Preterm labor (tocolysis)","description":"Sometimes used off-label to delay premature labor, but this use is not approved and requires specialist supervision.","evidence":"Limited"},{"condition":"Anal fissure","description":"Topical nifedipine has been used off-label to help heal anal fissures by relaxing smooth muscle.","evidence":"Limited"},{"condition":"High-altitude pulmonary edema prevention","description":"Nifedipine may be used off-label to prevent high-altitude pulmonary edema in susceptible individuals.","evidence":"Moderate"}]
Primary treatment for: Hypertension
Also treats: Angina pectoris, Raynaud's phenomenon
📋 Drug Information
| Generic Name(s) | Nifedipine (20mg) |
| Brand Name | n-dip 20mg tablet |
| Manufacturer | Taurus Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Calcium channel blockers- Dihydropyridines (DHP) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container, tightly closed. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization includes nifedipine in its Model List of Essential Medicines for the treatment of hypertension and angina. It is recommended as one of the options for managing high blood pressure, especially in low-resource settings. |
| ICMR Guideline | The Indian Council of Medical Research (ICMR) guidelines for the management of hypertension recommend calcium channel blockers like nifedipine as first-line therapy for hypertension, either alone or in combination with other antihypertensive agents. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking L-type calcium channels in the smooth muscle cells of blood vessels. By preventing calcium from entering these cells, it reduces the availability of calcium needed for muscle contraction. This leads to relaxation and widening of the blood vessels, particularly the arteries. As a result, peripheral vascular resistance decreases, blood pressure falls, and the heart's workload is reduced. In the coronary arteries, this effect improves blood flow and helps prevent spasms that can cause angina.
Mechanism Steps
💡 How to Take n-dip 20mg tablet
Strength: Sustained-release tablet, 20 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 20 mg to 40 mg once daily, taken orally. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. The maximum recommended dose is 120 mg per day, but doses above 60 mg per day are rarely used. This medicine should be swallowed whole with a glass of water and should not be crushed or chewed. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine, especially its blood pressure-lowering effect. Start with a lower dose and titrate slowly. Monitor blood pressure and heart rate closely. |
| Renal Impairment | No specific dose adjustment is required for patients with renal impairment. However, use with caution and monitor renal function. |
| Hepatic Impairment | In patients with hepatic impairment, the clearance of nifedipine may be reduced, leading to increased drug levels. Start with a lower dose and titrate slowly under close medical supervision. |
| Maximum Daily Dose | The maximum recommended daily dose is 120 mg, but doses above 60 mg per day are rarely used. The dose should be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of n-dip 20mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Rifampin | Major | |
| Grapefruit juice | Major | |
| Metoprolol | Major | |
| Prazosin | Major | |
| Digoxin | Moderate | |
| Cimetidine | Moderate | |
| Quinidine | Moderate | |
| Warfarin | Moderate | |
| Tacrolimus | Moderate |
🚨 Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin, ritonavir)
- CYP3A4 inducers (e.g., rifampin, carbamazepine, phenytoin, St. John's wort)
- Grapefruit juice
- Beta-blockers (e.g., metoprolol, atenolol)
- Alpha-blockers (e.g., prazosin, terazosin)
⚡ Moderate Interactions
- Digoxin
- Cimetidine
- Quinidine
- Warfarin
- Tacrolimus
🍷 Alcohol Interaction
Alcohol may increase the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and fainting. It is advisable to avoid or strictly limit alcohol consumption while taking this medicine. If you choose to drink, do so in moderation and monitor your blood pressure.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to nifedipine or other dihydropyridine calcium channel blockers","Cardiogenic shock","Severe aortic stenosis","Unstable angina (unless stabilized)","Within 4 weeks of a myocardial infarction","Concomitant use with rifampin"]
⚠️ Warnings & Precautions
["This medicine should be used with caution in patients with heart failure or severe coronary artery disease.","Abrupt withdrawal of this medicine can cause worsening of angina or rebound hypertension. Do not stop taking it without consulting your doctor.","This medicine may cause dizziness or lightheadedness. Avoid driving or operating machinery until you know how it affects you.","Peripheral edema is a common side effect and may require dose adjustment or additional treatment.","Use with caution in patients with liver or kidney impairment.","Grapefruit juice should be avoided while taking this medicine.","This medicine may interact with many other drugs. Always inform your doctor about all medicines you are taking."]
🤱 Lactation Safety
Nifedipine is excreted in breast milk in small amounts. It is generally considered compatible with breastfeeding, but you should consult your doctor before using this medicine while breastfeeding. Monitor the infant for any signs of adverse effects.
💊 Overdose Management
Overdose of this medicine can cause severe hypotension, tachycardia, bradycardia, and shock. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include intravenous fluids, vasopressors, and calcium gluconate. Gastric lavage may be considered if the overdose is recent. Hemodialysis is not effective in removing nifedipine.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Before you start taking this medicine, tell your doctor if you have any heart conditions, liver problems, kidney problems, or if you are pregnant or planning to become pregnant. Do not stop taking this medicine suddenly without talking to your doctor, as this can cause your blood pressure to rise or trigger chest pain. Take this medicine exactly as prescribed, usually once daily, and try to take it at the same time each day. Swallow the tablet whole with a glass of water; do not crush, chew, or break it because it is a sustained-release formulation. Avoid drinking grapefruit juice while taking this medicine, as it can increase the amount of medicine in your blood and cause side effects. Alcohol may enhance the blood pressure-lowering effect and cause dizziness, so it is best to limit or avoid alcohol. If you feel dizzy or lightheaded when standing up, rise slowly. This medicine may cause drowsiness or dizziness in some people; avoid driving or operating heavy machinery until you know how it affects you. Keep all your medical appointments and have your blood pressure checked regularly. Store this medicine at room temperature, away from moisture and direct sunlight, and keep it out of the reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and titrate slowly. Monitor blood pressure and heart rate closely. Elderly patients are also at higher risk of dizziness and falls. Take precautions to prevent falls, especially when getting up from a sitting or lying position.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. This medicine is generally considered safe during pregnancy, but your doctor may adjust your treatment plan. It is important to control high blood pressure during pregnancy to ensure the health of both mother and baby.
🏥 Post-Surgery Considerations
If you are undergoing surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with certain anesthetic agents and can affect blood pressure during surgery. Your doctor may advise you to temporarily stop the medicine before surgery. Do not stop it on your own.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. This medicine may cause gingival hyperplasia (overgrowth of gums) in rare cases, which can complicate dental work. It may also interact with certain local anesthetics or sedatives. Your dentist may need to take special precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is beneficial for managing high blood pressure, but you should avoid sudden strenuous activities until you know how this medicine affects you. This medicine may cause dizziness or lightheadedness, especially when you start taking it or when the dose is increased. Warm up gradually and cool down after exercise. If you experience chest pain, severe shortness of breath, or dizziness during exercise, stop and seek medical attention.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or lightheadedness, especially when you first start taking it or when the dose is increased. Avoid driving or operating heavy machinery until you know how it affects you. If your work involves operating machinery or driving, inform your employer and take necessary precautions. Most people can continue their normal daily activities once they adjust to the medicine.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as severe hypotension, worsening angina, or allergic reactions, seek immediate medical attention. Your doctor may adjust the dose or switch to a different medicine if needed. Abrupt withdrawal can cause rebound hypertension or worsening of angina.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for managing high blood pressure and angina. Regular monitoring of blood pressure, heart rate, and signs of peripheral edema is recommended. Some patients may develop tolerance or require dose adjustments over time. Long-term use has not been associated with significant organ toxicity, but liver and kidney function should be monitored in patients with pre-existing conditions. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, weight loss, and stress reduction can help lower blood pressure and reduce the need for medication.
Evidence: Well-establishedACE inhibitors, ARBs, diuretics, and beta-blockers are alternative options for managing hypertension.
Evidence: Well-establishedFor certain cases of angina or hypertension, procedures like angioplasty or surgery may be considered.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. You can receive vaccinations as recommended by your doctor. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or exposure to extreme temperatures. If crossing time zones, consult your doctor about how to adjust your dosing schedule. Store the medicine at room temperature and protect it from moisture and direct sunlight. Check the customs regulations of your destination regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts to lower blood pressure within 30 to 60 minutes, but the full effect may take several hours. It may take a few weeks to achieve optimal blood pressure control.
A: No, you should not stop taking this medicine without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause your blood pressure to rise again or trigger chest pain.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine can be used with other blood pressure medicines, but only under your doctor's supervision. Some combinations may increase the risk of low blood pressure or other side effects.
A: This medicine is generally considered safe during pregnancy when prescribed by a doctor. It is often used to treat high blood pressure in pregnant women. However, you should always consult your doctor before taking any medicine during pregnancy.
🤔 Common Patient Concerns
🔄 Substitutes for n-dip 20mg tablet
View AllAlternative brands with exact same active ingredient:
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calnif retard 20mg tabletCadila Pharmaceuticals Ltd ₹7.31 28.5% CHEAPER
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niferil retard 20mg tabletUSV Ltd ₹7.50 26.6% CHEAPER
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angiblock retard 20mg tabletAlkem Laboratories Ltd ₹7.97 22% CHEAPER
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cardipin 20mg tabletIntas Pharmaceuticals Ltd ₹9.94 2.7% CHEAPER
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nepin 20mg tablet srLincoln Pharmaceuticals Ltd ₹11.25 10.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure high blood pressure permanently.
Fact: This medicine controls high blood pressure but does not cure it. You need to continue taking it as prescribed to keep your blood pressure under control. - Myth: You can stop taking this medicine once your blood pressure is normal.
Fact: Stopping this medicine suddenly can cause your blood pressure to rise again and may trigger chest pain. Always consult your doctor before stopping. - Myth: This medicine is only for older people.
Fact: High blood pressure can affect people of all ages. This medicine can be prescribed to adults of any age if clinically indicated. - Myth: Taking this medicine means you can eat whatever you want.
Fact: A healthy diet and lifestyle are important for managing blood pressure. This medicine works best when combined with a low-salt diet and regular exercise.
🔄 Alternative Options
Generic Alternatives
- Nifedipine sustained-release tablet
Brand Alternatives
- Angifine 20mg Tablet SR
- Nifedine 20mg Tablet SR
- Depin 20mg Tablet SR