cabaza tablet er

4.5 (14 reviews)

Pentoxifylline (400mg)

🏭 Jolly Healthcare 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is cabaza tablet er used for?

Cabaza Tablet (Pentoxifylline) is used to treat CARDIAC. It contains Pentoxifylline (400mg), which Improves erythrocyte flexibility, reduces blood viscosity, and inhibits platelet. Always consult your doctor before use. Take as prescribed.

Generic Name: Pentoxifylline
Manufacturer: Jolly Healthcare
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 cabaza tablet er Uses & Benefits

Intermittent claudication, peripheral vascular disease, cerebrovascular insufficiency.

Off-label uses: Venous leg ulcers, diabetic neuropathy, sickle cell disease, alcoholic hepatitis.

📋 Drug Information

Generic Name(s)	Pentoxifylline
Brand Name	Cabaza Tablet
Manufacturer	Jolly Healthcare
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	CARDIAC
Action Class	Rheologic modifier
Route of Administration	Oral
Storage	Store at room temperature (20-25°C), protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract.

DistributionDistributes widely in tissues, including erythrocytes.

Protein BindingApproximately 95% bound to plasma proteins.

MetabolismHepatic metabolism via reduction and oxidation, primarily to active metabolites.

Half-Life0.4-0.8 hours for parent drug; metabolites have longer half-life (1-1.6 hours).

ExcretionPrimarily renal excretion of metabolites; less than 4% excreted unchanged.

BioavailabilityApproximately 20-30% due to first-pass metabolism.

Onset of ActionWithin 2-4 weeks for clinical effect in intermittent claudication.

Peak Plasma Time2-4 hours after oral administration.

Duration of ActionNot well defined; sustained release formulation provides prolonged effect.

How It Works

Improves erythrocyte flexibility, reduces blood viscosity, and inhibits platelet aggregation.

Mechanism Steps

1Inhibits phosphodiesterase (PDE4) in erythrocytes and vascular smooth muscle.

2Increases intracellular cAMP levels.

3Enhances erythrocyte deformability by reducing membrane viscosity.

💡 How to Take cabaza tablet er

Follow your doctor's prescription exactly.

⚠️ Side Effects of cabaza tablet er

✅ Common Side Effects

Nausea
Vomiting
Dizziness
Headache
Flushing

🚨 Serious Side Effects

Bleeding
Arrhythmias
Hypotension
Seizures
Anaphylaxis

⚠️ Rare Side Effects

Cholestatic hepatitis
Aplastic anemia
Thrombocytopenia
Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Anticoagulants	Major	Enhanced anticoagulant effect
Antiplatelet agents	Major	Increased risk of bleeding
Theophylline	Major	Increased theophylline levels and toxicity
Antihypertensives	Moderate	Additive hypotensive effect
Insulin	Moderate	Enhanced hypoglycemic effect
Oral hypoglycemics	Moderate	Enhanced hypoglycemic effect
Cimetidine	Minor	Increased pentoxifylline levels
Probenecid	Minor	Increased pentoxifylline levels

🚨 Major Interactions

Warfarin
Anticoagulants
Antiplatelet agents
Theophylline

⚡ Moderate Interactions

Antihypertensives
Insulin
Oral hypoglycemics

ℹ️ Minor Interactions

Cimetidine
Probenecid

🍽️ Food Interactions

No significant food interactions reported.

🍷 Alcohol Interaction

May increase risk of bleeding; avoid excessive alcohol consumption.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to pentoxifylline or methylxanthines, recent cerebral or retinal hemorrhage, active peptic ulcer.

📊 Monitoring Parameters

Monitor for bleeding signs, blood pressure, blood glucose in diabetics, and renal function.

🤱 Lactation Safety

Not recommended; excreted in breast milk.

💊 Overdose Management

Symptomatic and supportive treatment; induce emesis or gastric lavage; monitor for hypotension, arrhythmias, seizures.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for cabaza tablet er

View All

Alternative brands with exact same active ingredient (Pentoxifylline (400mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.