cytoflu 500mg tablet - Uses, Price, Side Effects & Substitutes
What is cytoflu 500mg tablet used for?
Cytoflu 500mg Tablet (Flucytosine) is used to treat ANTI INFECTIVES. It contains Flucytosine (500mg), which Flucytosine is converted intracellularly to 5-fluorouracil, which inhibits funga. Always consult your doctor before use. Take as prescribed.
- Generic Name: Flucytosine
- Manufacturer: Jolly Healthcare
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ cytoflu 500mg tablet Uses & Benefits
Treatment of systemic fungal infections, particularly candidiasis and cryptococcosis (often used in combination with amphotericin B).
Off-label uses: Chromomycosis, Aspergillosis (limited data)
๐ Drug Information
| Generic Name(s) | Flucytosine |
| Brand Name | Cytoflu 500mg Tablet |
| Manufacturer | Jolly Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Fluorinated pyrimidine-antifungal |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Flucytosine is converted intracellularly to 5-fluorouracil, which inhibits fungal RNA and DNA synthesis by incorporating into RNA and inhibiting thymidylate synthase.
Mechanism Steps
๐ก How to Take cytoflu 500mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cytoflu 500mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Rash
- Abdominal pain
๐จ Serious Side Effects
- Bone marrow suppression (leukopenia, thrombocytopenia)
- Hepatotoxicity
- Cardiotoxicity (rare)
โ ๏ธ Rare Side Effects
- Confusion
- Hallucinations
- Peripheral neuropathy
- Photosensitivity
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Amphotericin B | Major | Increased nephrotoxicity and synergistic antifungal effect |
| Cytarabine | Major | Reduced flucytosine efficacy (competitive inhibition) |
| Ganciclovir | Major | Increased risk of myelosuppression |
| Myelosuppressive agents | Moderate | Additive bone marrow suppression |
| Nephrotoxic drugs | Moderate | Increased risk of renal impairment |
| Probenecid | Minor | Decreased renal excretion of flucytosine |
๐จ Major Interactions
- Amphotericin B
- Cytarabine
- Ganciclovir
โก Moderate Interactions
- Myelosuppressive agents
- Nephrotoxic drugs
โน๏ธ Minor Interactions
- Probenecid
๐ฝ๏ธ Food Interactions
No significant food interactions reported.
๐ท Alcohol Interaction
Avoid alcohol as it may increase hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to flucytosine or any component; severe renal impairment (CrCl < 20 mL/min) without dose adjustment.
๐ Monitoring Parameters
Renal function, liver function, complete blood count (CBC), serum drug levels (if available), and fungal culture.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk.
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination.
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for cytoflu 500mg tablet
View AllAlternative brands with exact same active ingredient (Flucytosine (500mg)):
-
fcfung 500 tabletGlenmark Pharmaceuticals Ltd โน1,312.50 89.6% CHEAPER
-
cytorx 500mg tabletCipla Ltd โน1,475.00 88.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.