cytoflu 500mg tablet - Flucytosine (500mg) medicine

Cytoflu 500mg Tablet (Flucytosine): Complete Medicine Guide

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🏭 Jolly Healthcare 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: High for cryptococcal meningitis in combination therapy; moderate for other indications.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Unusual bleeding or bruising
  • Fever, chills, or signs of infection
  • Severe fatigue or weakness
  • Yellowing of skin or eyes (jaundice)
  • Dark urine or decreased urine output
  • Severe abdominal pain
  • Shortness of breath or difficulty breathing
  • Rash with blistering or peeling skin

If experiencing severe symptoms, call emergency services immediately.

What is cytoflu 500mg tablet used for?

This medicine is an antifungal medication used in combination with other antifungals to treat serious fungal infections such as cryptococcal meningitis and invasive candidiasis. It works by stopping the growth of fungi. It requires regular blood monitoring due to the risk of bone marrow suppression.

  • Generic Name: Flucytosine
  • Manufacturer: Jolly Healthcare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cytoflu 500mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एक एंटीफंगल दवा है जिसका उपयोग गंभीर फंगल संक्रमणों जैसे क्रिप्टोकोकल मेनिनजाइटिस और इनवेसिव कैंडिडिआसिस के इलाज के लिए किया जाता है। यह अन्य एंटीफंगल दवाओं के साथ मिलकर काम करती है और फंगस को बढ़ने से रोकती है। यह दवा केवल डॉक्टर की देखरेख में ही लेनी चाहिए क्योंकि इससे खून की कोशिकाओं पर असर पड़ सकता है और नियमित रक्त जांच की आवश्यकता होती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभावों में रक्त कोशिकाओं का कम बनना, जिससे एनीमिया, संक्रमण का खतरा और रक्तस्राव की समस्या हो सकती है, शामिल है। लीवर और किडनी पर भी असर हो सकता है। इसलिए नियमित रक्त जांच और डॉक्टर की निगरानी बहुत जरूरी है।

सुरक्षा सलाह: इस दवा को केवल डॉक्टर के निर्देशानुसार ही लें। नियमित रक्त जांच करवाते रहें ताकि खून, लीवर और किडनी पर पड़ने वाले असर का पता चल सके। दवा को भोजन के साथ या बिना भोजन के ले सकते हैं, लेकिन अगर पेट खराब लगे तो भोजन के साथ लें। शराब न पिएं क्योंकि इससे लीवर पर असर बढ़ सकता है। दवा लेना अचानक बंद न करें, डॉक्टर से पूछकर ही बंद करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 cytoflu 500mg tablet Uses & Benefits

[{"condition":"Cryptococcal meningitis","description":"This medicine is used in combination with amphotericin B, with or without fluconazole, for the treatment of cryptococcal meningitis, a serious fungal infection of the membranes surrounding the brain and spinal cord.","evidence":"Well-established"},{"condition":"Invasive candidiasis","description":"This medicine may be used as part of combination therapy for severe invasive candidiasis, including candidemia, when other antifungal agents are not adequate or are contraindicated.","evidence":"Established"},{"condition":"Chromoblastomycosis","description":"This medicine has been used in the treatment of chromoblastomycosis, a chronic fungal infection of the skin and subcutaneous tissues, although it is not a first-line treatment.","evidence":"Limited"}]

Off-label uses: [{"condition":"Aspergillosis","description":"This medicine has been used off-label in combination with other antifungals for the treatment of invasive aspergillosis, but its role is not well defined.","evidence":"Limited"},{"condition":"Cryptococcosis in immunocompromised patients","description":"This medicine may be used off-label for maintenance therapy in patients with HIV/AIDS and cryptococcal disease after initial treatment.","evidence":"Limited"}]

Primary treatment for: Cryptococcal meningitis

Also treats: Invasive candidiasis, Chromoblastomycosis

📋 Drug Information

Generic Name(s)Flucytosine
Brand NameCytoflu 500mg Tablet
ManufacturerJolly Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassFluorinated pyrimidine-antifungal
Route of AdministrationOral
StorageStore this medicine at room temperature between 15°C and 30°C (59°F to 86°F) in a dry place, away from direct sunlight and moisture. Keep it in its original container, tightly closed.
Shelf LifeThe shelf life of this medicine is typically 24 months from the date of manufacture, but refer to the packaging for the exact expiry date.
WHO GuidelineThe World Health Organization recommends flucytosine in combination with amphotericin B as the preferred induction therapy for cryptococcal meningitis in adults, adolescents, and children. This combination is also recommended for the treatment of invasive candidiasis in certain settings.
ICMR GuidelineThe Indian Council of Medical Research guidelines for the management of cryptococcal meningitis recommend the use of flucytosine in combination with amphotericin B for induction therapy, followed by fluconazole for consolidation and maintenance therapy.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine in combination with other antifungals as prescribed, because using it alone can lead to resistance.
2
Regular blood tests are mandatory to monitor for bone marrow suppression, liver, and kidney function.
3
Take this medicine with food if it causes stomach upset, but maintain consistent timing with respect to meals.
4
Avoid alcohol completely while on this medicine to reduce the risk of liver toxicity.
5
Report any unusual bleeding, bruising, fever, or fatigue immediately to your doctor.
6
Do not stop this medicine without consulting your doctor, even if you feel better, to prevent relapse.
7
Inform your doctor about all other medicines you are taking, especially other antifungals and nephrotoxic drugs.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Severe headache with fever and neck stiffness
This medicine is commonly prescribed for cryptococcal meningitis.
Likely Use
✅
Persistent fever with chills in immunocompromised patient
This medicine may be used for invasive candidiasis.
Likely Use
❌
Athlete's foot or ringworm
This medicine is not used for superficial fungal infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration, with a bioavailability of approximately 80-90%. Food does not significantly affect the extent of absorption, but it may delay the time to peak concentration.
DistributionThis medicine is widely distributed throughout the body, including into the cerebrospinal fluid, where it achieves concentrations that are approximately 60-90% of plasma levels. It also distributes into other tissues and body fluids, including peritoneal fluid, synovial fluid, and aqueous humor.
Protein BindingThis medicine has minimal protein binding, approximately 2-4%, meaning that most of the drug is free and pharmacologically active in the bloodstream.
MetabolismThis medicine is minimally metabolized in humans. It is primarily excreted unchanged by the kidneys, and only a small amount is converted to 5-fluorouracil in the body.
Half-LifeThe elimination half-life of this medicine is approximately 2.5 to 6 hours in patients with normal kidney function, but it can be significantly prolonged in patients with renal impairment.
ExcretionThis medicine is primarily excreted unchanged in the urine by glomerular filtration, with about 90% of the administered dose recovered in the urine within 24 hours. Renal clearance is the major route of elimination.
BioavailabilityThe oral bioavailability of this medicine is approximately 80-90% in patients with normal gastrointestinal function.
Onset of ActionThe onset of antifungal action depends on the infection being treated and the combination therapy used. Clinical improvement may be seen within days to weeks, but full treatment courses often last several weeks to months.
Peak Plasma TimePeak plasma concentrations of this medicine are reached approximately 1 to 2 hours after oral administration in fasting conditions.
Duration of ActionThe duration of action of this medicine is not precisely defined, but its antifungal effect persists as long as therapeutic drug levels are maintained. Dosing is typically every 6 hours to maintain adequate levels.

How It Works

This medicine works by entering fungal cells and being converted into 5-fluorouracil, which is then incorporated into fungal RNA and inhibits DNA synthesis. This dual action disrupts protein synthesis and cell division, leading to fungal cell death. It is primarily fungistatic against susceptible fungi, meaning it stops their growth rather than directly killing them, and its effectiveness depends on the immune system of the patient and the combination with other antifungal agents.

Mechanism Steps

1
Entry into fungal cell: This medicine is taken up by fungal cells through a specific permease enzyme that is not present in human cells, which contributes to its selective toxicity.
2
Conversion to 5-fluorouracil: Inside the fungal cell, this medicine is rapidly converted to 5-fluorouracil by the enzyme cytosine deaminase.
3
Incorporation into RNA: 5-fluorouracil is converted to 5-fluorouridine triphosphate, which is incorporated into fungal RNA, leading to faulty protein synthesis and inhibition of cell growth.
4
Inhibition of DNA synthesis: 5-fluorouracil is also converted to 5-fluoro-2'-deoxyuridine-5'-monophosphate, which inhibits thymidylate synthase, thereby blocking DNA synthesis and cell division.
5
Fungal cell death: The combined effects on RNA and DNA synthesis lead to inhibition of fungal growth and eventually cell death, especially when the immune system is functioning.

💡 How to Take cytoflu 500mg tablet

Strength: This medicine is available as a 500mg immediate-release tablet for oral administration.

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3You may take it with or without food, but if it upsets your stomach, take it with a meal or snack.
4Take the doses at evenly spaced intervals, usually every 6 hours.
5Do not crush, chew, or break the tablet unless your doctor advises you to.
6Do not stop taking this medicine without consulting your doctor, even if you feel better.
7Keep all your appointments for blood tests and follow-up visits.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 50 to 150 mg per kilogram of body weight per day, divided into four doses given every 6 hours. The exact dose depends on the type and severity of the fungal infection, the patient's kidney function, and whether it is used alone or with other antifungal medicines. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Regular blood tests are required to monitor for toxicity and to adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced kidney function, which can increase the risk of toxicity from this medicine. Dose adjustment based on creatinine clearance is recommended. Close monitoring of blood counts, liver, and kidney function is advised.
Renal ImpairmentIn patients with renal impairment, the dose of this medicine must be reduced and the dosing interval extended based on creatinine clearance. For creatinine clearance 20-40 mL/min, the dose may be reduced to 25-50 mg/kg/day; for creatinine clearance 10-20 mL/min, further reduction is needed. In patients on hemodialysis, an additional dose may be required after dialysis. Dose must be individualized by a qualified clinician.
Hepatic ImpairmentIn patients with hepatic impairment, this medicine should be used with caution. No specific dose adjustment guidelines are available, but liver function should be monitored closely. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum recommended daily dose of this medicine is 150 mg/kg/day, but this may be lower depending on renal function and toxicity. Dose must be individualized by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
May increase risk of liver toxicity.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of cytoflu 500mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take this medicine with food or milk to reduce nausea. If nausea persists, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated and inform your doctor if vomiting is severe or persistent.
Diarrhea (Common (5-10%))
Drink plenty of fluids. If diarrhea is severe or contains blood, seek medical attention.
Abdominal pain (Common (5-10%))
Take with food and avoid spicy meals. Consult doctor if pain is severe.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if headache is severe or persistent.
Skin rash (Uncommon (1-5%))
Report to your doctor. If rash is accompanied by fever or blistering, seek immediate medical attention.

🚨 Serious Side Effects

Bone marrow suppression (anemia, neutropenia, thrombocytopenia) (Uncommon to common (up to 10-20% in high-dose therapy))
Regular blood tests are required. Report any signs of infection, unusual bleeding, or fatigue immediately.
Hepatotoxicity (liver damage) (Rare (<1%))
Report yellowing of skin or eyes, dark urine, or severe abdominal pain. Liver function tests should be monitored.
Nephrotoxicity (kidney damage) (Rare (<1%))
Monitor kidney function. Report decreased urine output or swelling.
Severe skin reactions (e.g., toxic epidermal necrolysis) (Very rare (<0.1%))
Seek immediate medical attention if you develop a painful rash with blistering or peeling skin.
Anaphylaxis (Very rare (<0.1%))
Seek emergency medical help if you experience difficulty breathing, swelling of face or throat, or severe dizziness.

⚠️ Rare Side Effects

Peripheral neuropathy
Report numbness, tingling, or weakness in hands or feet to your doctor.
Pancreatitis
Seek medical attention if you experience severe upper abdominal pain radiating to the back.
Seizures
Seek emergency medical help if seizures occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Amphotericin B Major
Fluconazole Major
Cytarabine Major
Aminoglycosides Moderate
NSAIDs Moderate
Methotrexate Moderate
Isoniazid Moderate
Antacids Minor

🚨 Major Interactions

  • Amphotericin B
  • Fluconazole
  • Cytarabine

⚡ Moderate Interactions

  • Nephrotoxic drugs (e.g., aminoglycosides, NSAIDs)
  • Hepatotoxic drugs (e.g., methotrexate, isoniazid)

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it may increase the risk of liver toxicity and worsen side effects such as nausea and dizziness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to flucytosine or any component of the formulation","Severe renal impairment (creatinine clearance < 20 mL/min) without dose adjustment and monitoring","Severe hepatic impairment","Pregnancy (unless the potential benefit outweighs the risk)","Breastfeeding (unless the potential benefit outweighs the risk)"]

⚠️ Warnings & Precautions

["This medicine can cause severe bone marrow suppression, leading to anemia, neutropenia, and thrombocytopenia. Regular blood counts are essential.","This medicine should be used with caution in patients with renal impairment. Dose adjustment is required based on creatinine clearance.","This medicine should be used with caution in patients with liver disease. Liver function should be monitored.","This medicine may cause severe skin reactions. Patients should be advised to report any rash immediately.","This medicine should not be used as monotherapy for serious fungal infections due to the risk of resistance.","Patients should be advised to avoid alcohol while taking this medicine.","This medicine may impair the ability to drive or operate machinery if dizziness or fatigue occurs."]

🤱 Lactation Safety

It is not known whether this medicine is excreted in human breast milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

💊 Overdose Management

Overdose of this medicine can cause severe bone marrow suppression, liver toxicity, and kidney toxicity. There is no specific antidote. Treatment is supportive and symptomatic. In case of overdose, stop the medicine and seek immediate medical attention. Hemodialysis may be considered to remove the drug from the bloodstream in severe cases.

⏰ Missed Dose

If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

This medicine must only be taken under the supervision of a qualified clinician, and regular blood tests are essential to monitor for bone marrow suppression, liver, and kidney problems. Take this medicine exactly as prescribed, with or without food, but if it causes stomach upset, take it with a meal or snack. Do not stop taking this medicine without consulting your doctor, even if you feel better, because stopping early can lead to the infection returning or becoming resistant. Inform your doctor about all other medicines you are taking, especially other antifungals, because this medicine can interact with them. Avoid alcohol while taking this medicine as it may increase the risk of liver problems. If you miss a dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Keep this medicine out of reach of children and store it at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more likely to have reduced kidney function, which can increase the risk of toxicity from this medicine. Dose adjustment based on creatinine clearance is recommended. Close monitoring of blood counts, liver, and kidney function is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, discuss with your doctor before taking this medicine. This medicine is Pregnancy Category C and should be used during pregnancy only if the potential benefit justifies the potential risk. Effective contraception should be used during treatment.

🏥 Post-Surgery Considerations

If you have recently had surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may affect wound healing and increase the risk of bleeding or infection. Close monitoring is advised.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. This medicine can increase the risk of bleeding and infection, so your dentist may take extra precautions.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy diet rich in fruits and vegetables to support your immune system.
🥗
Stay well hydrated to help your kidneys flush out the medicine.
😴
Get adequate rest to help your body fight the infection.
💧
Avoid alcohol to reduce the risk of liver problems.
🧘
Practice good hygiene to prevent secondary infections.
🌞
Keep all your medical appointments for monitoring.

🏋️ Exercise Considerations

This medicine may cause fatigue or dizziness. Avoid strenuous exercise if you feel weak or dizzy. Light activities like walking are generally safe, but consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include protein-rich foods to support recovery.
Eat small, frequent meals if you have nausea.
Avoid spicy and greasy foods if you have stomach upset.
Stay well hydrated with water and clear fluids.

💼 Impact on Daily Work & Life

This medicine may cause fatigue, dizziness, or nausea, which can affect your ability to drive or operate machinery. It is advisable to avoid driving or operating heavy machinery until you know how this medicine affects you. You may need to take time off work during the initial phase of treatment.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Your doctor will decide when to stop based on your response to treatment and blood test results. Stopping early can lead to relapse or resistance.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of bone marrow suppression, liver toxicity, and kidney toxicity. Regular monitoring of blood counts, liver, and kidney function is essential. The risk of these effects increases with higher doses and longer duration of therapy. Patients should be monitored closely and dose adjustments made as needed.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Amphotericin B monotherapy

May be used as an alternative if this medicine is not tolerated or contraindicated, but it has more side effects.

Evidence: Well-established
Fluconazole monotherapy

May be used for less severe infections or as maintenance therapy.

Evidence: Established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions with this medicine. However, live vaccines should be avoided in immunocompromised patients. Consult your doctor before receiving any vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or temperature extremes. If crossing time zones, adjust dosing times gradually in consultation with your doctor. Store at room temperature and avoid leaving it in a hot car. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with HIV presented with severe headache and fever, diagnosed with cryptococcal meningitis.
He was started on this medicine in combination with amphotericin B. He experienced nausea and vomiting initially, which improved when the medicine was taken with food. Regular blood tests showed a slight drop in white blood cell count, but it was managed with dose adjustment. After several weeks of treatment, his symptoms improved significantly.
💡 Lesson: Taking this medicine with food can reduce stomach upset, and regular monitoring allows early detection and management of side effects.
👤 A 60-year-old woman with diabetes developed invasive candidiasis after a prolonged hospital stay.
She was prescribed this medicine along with fluconazole. She was monitored closely with blood tests. She reported feeling tired and had some bruising, which prompted a blood test that showed low platelet count. The dose was adjusted, and her counts improved. She completed the treatment successfully.
💡 Lesson: Reporting unusual symptoms like fatigue and bruising can lead to early detection of blood-related side effects, which can be managed with dose adjustment.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Clinical improvement may be seen within days to weeks, but the full course of treatment may last several weeks to months depending on the infection.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. If it causes stomach upset, take it with a meal or snack.

Q: What should I do if I miss a dose?

A: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: This medicine is Pregnancy Category C. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor.

Q: Can I stop taking this medicine when I feel better?

A: No, you should complete the full course as prescribed. Stopping early can lead to the infection returning or becoming resistant.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for cytoflu 500mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any fungal infection.
    Fact: This medicine is only effective against certain serious systemic fungal infections and is not used for common superficial fungal infections like athlete's foot.
  • Myth: This medicine is safe to take without blood tests.
    Fact: This medicine can cause serious blood-related side effects, so regular blood tests are mandatory during treatment.
  • Myth: This medicine can be stopped as soon as symptoms improve.
    Fact: Stopping this medicine early can lead to the infection returning or becoming resistant. Always complete the full course as prescribed.

🔄 Alternative Options

Generic Alternatives

  • Flucytosine 500mg tablet

Brand Alternatives

  • Ancobon
  • Flucytosine

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","class":"Antimetabolite antifungal","route":"Oral","main_use":"Cryptococcal meningitis, invasive candidiasis","key_side_effect":"Bone marrow suppression"},{"medicine":"Fluconazole","class":"Triazole antifungal","route":"Oral, intravenous","main_use":"Cryptococcal meningitis, candidiasis","key_side_effect":"Liver toxicity, QT prolongation"},{"medicine":"Amphotericin B","class":"Polyene antifungal","route":"Intravenous","main_use":"Serious systemic fungal infections","key_side_effect":"Nephrotoxicity, infusion reactions"}]

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