cabaza tablet - Pentoxifylline (400mg) medicine

cabaza tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Jolly Healthcare ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jul 2, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jul 02, 2026

What is cabaza tablet used for?

Cabaza Tablet (Pentoxifylline) is used to treat CARDIAC. It contains Pentoxifylline (400mg), which Improves erythrocyte flexibility, reduces blood viscosity, and inhibits platelet. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Pentoxifylline
  • Manufacturer: Jolly Healthcare
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š cabaza tablet Uses & Benefits

Intermittent claudication, peripheral vascular disease, cerebrovascular insufficiency.

Off-label uses: Venous leg ulcers, diabetic neuropathy, sickle cell disease, alcoholic hepatitis.

๐Ÿ“‹ Drug Information

Generic Name(s)Pentoxifylline
Brand NameCabaza Tablet
ManufacturerJolly Healthcare
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassRheologic modifier
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract.
DistributionDistributes widely in tissues, including erythrocytes.
Protein BindingApproximately 95% bound to plasma proteins.
MetabolismHepatic metabolism via reduction and oxidation, primarily to active metabolites.
Half-Life0.4-0.8 hours for parent drug; metabolites have longer half-life (1-1.6 hours).
ExcretionPrimarily renal excretion of metabolites; less than 4% excreted unchanged.
BioavailabilityApproximately 20-30% due to first-pass metabolism.
Onset of ActionWithin 2-4 weeks for clinical effect in intermittent claudication.
Peak Plasma Time2-4 hours after oral administration.
Duration of ActionNot well defined; sustained release formulation provides prolonged effect.

How It Works

Improves erythrocyte flexibility, reduces blood viscosity, and inhibits platelet aggregation.

Mechanism Steps

1Inhibits phosphodiesterase (PDE4) in erythrocytes and vascular smooth muscle.
2Increases intracellular cAMP levels.
3Enhances erythrocyte deformability by reducing membrane viscosity.

๐Ÿ’ก How to Take cabaza tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cabaza tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Dizziness
  • Headache
  • Flushing

๐Ÿšจ Serious Side Effects

  • Bleeding
  • Arrhythmias
  • Hypotension
  • Seizures
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Cholestatic hepatitis
  • Aplastic anemia
  • Thrombocytopenia
  • Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Anticoagulants Major Enhanced anticoagulant effect
Antiplatelet agents Major Increased risk of bleeding
Theophylline Major Increased theophylline levels and toxicity
Antihypertensives Moderate Additive hypotensive effect
Insulin Moderate Enhanced hypoglycemic effect
Oral hypoglycemics Moderate Enhanced hypoglycemic effect
Cimetidine Minor Increased pentoxifylline levels
Probenecid Minor Increased pentoxifylline levels

๐Ÿšจ Major Interactions

  • Warfarin
  • Anticoagulants
  • Antiplatelet agents
  • Theophylline

โšก Moderate Interactions

  • Antihypertensives
  • Insulin
  • Oral hypoglycemics

โ„น๏ธ Minor Interactions

  • Cimetidine
  • Probenecid

๐Ÿฝ๏ธ Food Interactions

No significant food interactions reported.

๐Ÿท Alcohol Interaction

May increase risk of bleeding; avoid excessive alcohol consumption.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to pentoxifylline or methylxanthines, recent cerebral or retinal hemorrhage, active peptic ulcer.

๐Ÿ“Š Monitoring Parameters

Monitor for bleeding signs, blood pressure, blood glucose in diabetics, and renal function.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk.

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; induce emesis or gastric lavage; monitor for hypotension, arrhythmias, seizures.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jul 02, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cabaza tablet

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Alternative brands with exact same active ingredient (Pentoxifylline (400mg)):

Medical Note: Always consult your doctor before switching medications.

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