bupidural 5mg injection

4.7 (15 reviews)

Bupivacaine (5mg)

🏭 Cachet Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is bupidural 5mg injection used for?

Anawin Heavy 5mg Injection (Bupivacaine) is used to treat PAIN ANALGESICS. It contains Bupivacaine (5mg), which Blocks sodium channels in nerve cell membranes, inhibiting nerve impulse conduct. Always consult your doctor before use. Take as prescribed.

Generic Name: Bupivacaine
Manufacturer: Cachet Pharmaceuticals Pvt Ltd
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 bupidural 5mg injection Uses & Benefits

Spinal anesthesia for lower abdominal, pelvic, and lower limb surgeries; epidural anesthesia; peripheral nerve blocks.

Off-label uses: Intra-articular injection for postoperative pain; intravenous regional anesthesia (Bier block).

📋 Drug Information

Generic Name(s)	Bupivacaine
Brand Name	Anawin Heavy 5mg Injection
Manufacturer	Cachet Pharmaceuticals Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	PAIN ANALGESICS
Action Class	Local anaesthetic (Amides)
Route of Administration	Intrathecal (spinal), epidural, peripheral nerve block.
Storage	Store at 20-25°C; protect from light; do not freeze.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from the injection site; systemic absorption depends on dose, concentration, and vascularity of the site.

DistributionWidely distributed; highly bound to tissues; crosses the blood-brain barrier and placenta.

Protein BindingApproximately 95% bound to alpha-1-acid glycoprotein.

MetabolismPrimarily hepatic via CYP3A4 and CYP1A2 to pipecoloxylidine and desbutylbupivacaine.

Half-Life2.7 to 3.4 hours in adults; prolonged in neonates and hepatic impairment.

ExcretionRenal excretion of metabolites; less than 5% unchanged.

BioavailabilityNot applicable (administered parenterally); systemic absorption depends on route.

Onset of Action5 to 10 minutes for spinal anesthesia.

Peak Plasma Time15 to 30 minutes after injection.

Duration of Action2 to 4 hours for spinal anesthesia; longer with epinephrine.

How It Works

Blocks sodium channels in nerve cell membranes, inhibiting nerve impulse conduction.

Mechanism Steps

1Bupivacaine binds to the intracellular portion of voltage-gated sodium channels.

2Inhibits sodium influx, preventing depolarization of the nerve membrane.

3Blocks propagation of action potentials along the nerve axon.

💡 How to Take bupidural 5mg injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of bupidural 5mg injection

✅ Common Side Effects

Hypotension
Bradycardia
Nausea
Vomiting
Headache
Back pain

🚨 Serious Side Effects

Cardiac arrest
Arrhythmias
Seizures
Respiratory depression
Anaphylaxis
Spinal hematoma

⚠️ Rare Side Effects

Allergic dermatitis
Methhemoglobinemia
Peripheral nerve injury
Arachnoiditis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Class I antiarrhythmics	Major	Increased risk of cardiac toxicity
CYP3A4 inhibitors	Major	Increased bupivacaine levels
Beta-blockers	Moderate	Reduced hepatic clearance
Alcohol	Moderate	Additive CNS depression

🚨 Major Interactions

Class I antiarrhythmics
Other local anesthetics
CYP3A4 inhibitors

⚡ Moderate Interactions

Beta-blockers
Calcium channel blockers
Antihypertensives

ℹ️ Minor Interactions

Cimetidine
Ranitidine

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

May increase CNS depression; avoid excessive alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to bupivacaine or amide anesthetics, severe hypotension, complete heart block, spinal deformities, infection at injection site.

📊 Monitoring Parameters

Blood pressure, heart rate, respiratory rate, level of anesthesia, CNS status, cardiac monitoring.

🤱 Lactation Safety

Excreted in breast milk in small amounts; use with caution.

💊 Overdose Management

Discontinue injection; administer oxygen, IV fluids, vasopressors; treat seizures with benzodiazepines; manage cardiac toxicity with lipid emulsion therapy.

⏰ Missed Dose

Not applicable; administered by healthcare professional.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for bupidural 5mg injection

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Alternative brands with exact same active ingredient (Bupivacaine (5mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Certified Buyer Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026