acton-or tablet sr - Paracetamol (300mg) + Paracetamol (700mg) medicine

Acton-OR Tablet SR: Complete Medicine Guide

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🏭 Apex Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for pain and fever.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of the skin or eyes (jaundice)
  • Dark-colored urine or pale stools
  • Severe abdominal pain or tenderness
  • Blood in vomit or black, tarry stools
  • Swelling of the face, lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Severe skin rash with blisters or peeling
  • Unusual bleeding or bruising
  • Decreased urine output or swelling in the legs

If experiencing severe symptoms, call emergency services immediately.

What is acton-or tablet sr used for?

This medicine contains Paracetamol 1000 mg (300 mg + 700 mg) and is used for moderate to severe pain and fever. It works by blocking pain signals in the brain and reducing fever. The usual adult dose is one tablet every 6 to 8 hours, not exceeding 4 tablets in 24 hours. Do not take with alcohol or other Paracetamol products.

  • Generic Name: Paracetamol
  • Manufacturer: Apex Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 acton-or tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा पैरासिटामोल का एक संयोजन है जिसका उपयोग मध्यम से गंभीर दर्द और बुखार के इलाज के लिए किया जाता है। यह सिरदर्द, दांत दर्द, मांसपेशियों के दर्द, ऑस्टियोआर्थराइटिस के दर्द और सर्जरी के बाद के दर्द में राहत देती है। यह शरीर के तापमान को नियंत्रित करने वाले केंद्र पर काम करके बुखार को कम करती है। इस दवा को डॉक्टर की सलाह के अनुसार ही लें और निर्धारित मात्रा से अधिक न लें।

साइड इफेक्ट्स: आमतौर पर यह दवा सही मात्रा में लेने पर सुरक्षित मानी जाती है। कुछ लोगों को मतली, पेट में असहजता या हल्के दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अधिक मात्रा लेने पर लिवर को गंभीर नुकसान हो सकता है। अगर आपको आंखों या त्वचा का पीलापन, गहरे रंग का पेशाब, या पेट में तेज दर्द हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। निर्धारित मात्रा से अधिक न लें और बिना सलाह के लंबे समय तक न लें। इस दवा के साथ शराब न पिएं क्योंकि इससे लिवर को नुकसान का खतरा बढ़ जाता है। अगर आपको लिवर या किडनी की समस्या है, या आप अन्य पैरासिटामोल युक्त दवाएं ले रहे हैं, तो अपने डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 acton-or tablet sr Uses & Benefits

[{"condition":"Moderate to severe pain","description":"Provides relief from pain that has not responded to lower doses of Paracetamol alone, such as post-operative pain, dental pain, and musculoskeletal pain.","evidence":"Well-established"},{"condition":"Fever","description":"Reduces elevated body temperature by acting on the hypothalamic heat-regulating centre.","evidence":"Well-established"},{"condition":"Headache","description":"Effective for tension-type headaches and mild migraines when used at appropriate doses.","evidence":"Well-established"},{"condition":"Osteoarthritis pain","description":"Provides symptomatic relief of mild to moderate pain associated with osteoarthritis.","evidence":"Established"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes used off-label for preventing migraines, but evidence is limited and it is not a first-line option.","evidence":"Limited"},{"condition":"Cancer pain","description":"May be used as an adjunct in cancer pain management, but usually in combination with opioids.","evidence":"Limited"}]

Primary treatment for: Pain and fever

Also treats: Headache, Osteoarthritis, Dental pain, Post-operative pain

📋 Drug Information

Generic Name(s)Paracetamol
Brand NameActon-Or Tablet SR
ManufacturerApex Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassAnalgesic and Antipyretic
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C. Protect from moisture and direct sunlight. Keep in the original container.
Shelf LifeTypically 24 to 36 months from the date of manufacture. Check the expiry date on the pack.
WHO GuidelineParacetamol is included in the WHO Model List of Essential Medicines for pain and fever management.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to reduce the chance of stomach upset.
2
Do not exceed the maximum daily dose of 4 tablets in 24 hours, as this can cause serious liver damage.
3
Avoid alcohol completely while taking this medicine to protect your liver.
4
Check other medicines you are taking for Paracetamol content to avoid accidental overdose.
5
If you have liver or kidney disease, inform your doctor before taking this medicine.
6
Do not use this medicine for more than 3 days for fever or 10 days for pain without consulting a doctor.
7
Keep a record of when you take this medicine to avoid missing or doubling doses.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Moderate to severe pain
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine is used to reduce fever.
Likely Use
Mild headache
A lower dose of Paracetamol may be sufficient.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionParacetamol is rapidly and almost completely absorbed from the gastrointestinal tract after oral administration. The rate of absorption depends on the formulation and gastric emptying time. Peak plasma concentrations are usually reached within 30 to 60 minutes for immediate-release formulations.
DistributionParacetamol is distributed widely throughout most body tissues. It crosses the placenta and is present in breast milk in small amounts. The volume of distribution is approximately 0.8 to 1.0 L/kg in adults.
Protein BindingParacetamol is only minimally bound to plasma proteins, approximately 10 to 25 percent.
MetabolismParacetamol is primarily metabolized in the liver by conjugation with glucuronic acid and sulfate. A small fraction is metabolized by cytochrome P450 enzymes, particularly CYP2E1, to form a highly reactive intermediate called N-acetyl-p-benzoquinone imine (NAPQI). Under normal conditions, NAPQI is detoxified by glutathione. In overdose, glutathione stores are depleted, leading to liver injury.
Half-LifeThe elimination half-life of Paracetamol is typically 2 to 3 hours in adults with normal liver function. It may be prolonged in patients with liver disease or after overdose.
ExcretionParacetamol and its metabolites are excreted primarily in the urine. Approximately 90 percent of the administered dose is excreted as glucuronide and sulfate conjugates, and a small amount is excreted unchanged.
BioavailabilityThe oral bioavailability of Paracetamol is approximately 80 to 100 percent, although it may be slightly lower due to first-pass metabolism.
Onset of ActionPain relief usually begins within 30 to 60 minutes after oral administration. Fever reduction typically starts within 30 to 60 minutes.
Peak Plasma TimePeak plasma concentrations are reached within 30 to 60 minutes after oral administration of immediate-release formulations.
Duration of ActionThe analgesic and antipyretic effects of Paracetamol usually last for 4 to 6 hours.

How It Works

Paracetamol, the active ingredient in this medicine, produces analgesia and antipyresis primarily through central nervous system effects. It inhibits prostaglandin synthesis in the brain and spinal cord, which reduces pain perception and lowers fever. Unlike nonsteroidal anti-inflammatory drugs, it has minimal anti-inflammatory activity and does not significantly inhibit cyclooxygenase in peripheral tissues. The exact mechanism is not fully established, but it may involve activation of descending serotonergic pathways and inhibition of nitric oxide synthase.

Mechanism Steps

1
Central prostaglandin synthesis inhibition: Paracetamol inhibits the enzyme cyclooxygenase in the brain and spinal cord, reducing the production of prostaglandins that sensitize pain receptors.
2
Activation of descending pain pathways: It may activate descending serotonergic pathways that inhibit pain signals travelling up the spinal cord.
3
Hypothalamic temperature regulation: It acts on the hypothalamus to promote heat loss, thereby reducing fever.
4
Minimal peripheral effect: Unlike NSAIDs, it does not significantly inhibit peripheral prostaglandins, so it lacks anti-inflammatory and antiplatelet actions.

💡 How to Take acton-or tablet sr

Strength: Each tablet contains Paracetamol 300 mg and Paracetamol 700 mg, providing a total of 1000 mg Paracetamol.

1Swallow the tablet whole with a glass of water.
2Take with or without food, but taking with food may reduce stomach upset.
3Do not crush, chew, or break the tablet unless advised by your doctor.
4Follow the prescribed dose and frequency exactly.
5Do not take more than the maximum daily dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet (1000 mg Paracetamol) every 6 to 8 hours as needed for pain or fever. Do not exceed 4 tablets (4000 mg) in 24 hours. For elderly patients or those with liver or kidney impairment, a lower dose may be recommended. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to the effects of Paracetamol, especially if they have liver or kidney impairment. A lower dose may be appropriate. Consult your doctor for individualized dosing.
Renal ImpairmentIn patients with severe renal impairment (creatinine clearance less than 30 mL/min), the dosing interval should be increased to every 8 hours. Consult your doctor for dose adjustment.
Hepatic ImpairmentIn patients with mild to moderate liver impairment, the dose should be reduced or the dosing interval increased. In severe liver disease, Paracetamol is contraindicated. Consult your doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose of Paracetamol for adults is 4000 mg (4 tablets of this medicine) in 24 hours. Do not exceed this limit.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of liver damage.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of acton-or tablet sr

✅ Common Side Effects

Nausea (Common (1-10%))
Take the medicine with food or milk to reduce nausea. If it persists, consult your doctor.
Stomach discomfort (Common (1-10%))
Taking with food may help. Avoid alcohol. If pain is severe, contact your doctor.
Rash (Uncommon (0.1-1%))
Stop the medicine and consult your doctor if rash develops.

🚨 Serious Side Effects

Liver injury (Rare (<0.1%))
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) (Very rare (<0.01%))
Stop the medicine and seek emergency care if you develop a spreading rash with blisters or peeling skin.
Anaphylaxis (Very rare (<0.01%))
Seek emergency help if you experience swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Thrombocytopenia
Report unusual bruising or bleeding to your doctor.
Leukopenia
Consult your doctor if you develop frequent infections.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Carbamazepine Moderate
Phenytoin Moderate
Rifampicin Moderate
Isoniazid Moderate
Metoclopramide Minor
Cholestyramine Minor

🚨 Major Interactions

  • Warfarin
  • Alcohol

⚡ Moderate Interactions

  • Carbamazepine, phenytoin, rifampicin
  • Isoniazid

🍷 Alcohol Interaction

Avoid consuming alcohol while taking this medicine. Alcohol, especially when consumed regularly in large amounts, can increase the risk of severe liver damage from Paracetamol.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to Paracetamol or any component of the formulation","Severe liver disease or active liver failure","Severe kidney disease (use with caution)","Chronic alcohol abuse"]

⚠️ Warnings & Precautions

["Do not exceed the recommended dose. Taking more than the maximum daily dose can cause serious liver damage.","Avoid alcohol while taking this medicine.","Do not use other products containing Paracetamol simultaneously.","Consult your doctor if you have liver or kidney disease.","Stop use and seek medical help if you develop a skin rash or other allergic reaction.","Use with caution in malnourished patients or those with low glutathione levels.","Prolonged use should be under medical supervision."]

🤱 Lactation Safety

Paracetamol is excreted in breast milk in small amounts and is generally considered safe during breastfeeding. Consult your doctor for guidance.

💊 Overdose Management

Overdose of Paracetamol can cause severe liver injury, which may be delayed. Symptoms of overdose may include nausea, vomiting, abdominal pain, and loss of appetite. If you suspect an overdose, seek emergency medical attention immediately, even if you feel well. The antidote, N-acetylcysteine, is most effective when given within 8 to 10 hours of ingestion. Do not wait for symptoms to appear.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or use it for longer than advised. Avoid drinking alcohol while taking this medicine because it increases the risk of liver damage. Inform your doctor if you have liver or kidney problems, or if you are taking other medicines containing Paracetamol. Do not use other Paracetamol-containing products simultaneously to prevent accidental overdose. Keep this medicine out of reach of children. If you are pregnant or breastfeeding, consult your doctor before use. Store at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of Paracetamol, especially if they have liver or kidney impairment. A lower dose may be recommended. Regular monitoring of liver and kidney function is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Paracetamol is generally considered safe during pregnancy, but it should be used at the lowest effective dose for the shortest duration.

🏥 Post-Surgery Considerations

This medicine may be prescribed for post-operative pain. Follow your surgeon's instructions carefully. Do not exceed the recommended dose. Inform your surgeon if you have any liver or kidney problems.

🦷 Dental Procedures

This medicine can be used for dental pain. Inform your dentist that you are taking this medicine before any dental procedure. It does not usually interact with local anesthetics, but always consult your dentist.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints and muscles.
🥗
Stay physically active with low-impact exercises like walking or swimming.
😴
Practice good posture to prevent musculoskeletal pain.
💧
Include anti-inflammatory foods like fruits, vegetables, and omega-3 rich fish in your diet.
🧘
Get adequate sleep to help your body recover.
🌞
Manage stress through relaxation techniques like deep breathing or meditation.

🏋️ Exercise Considerations

This medicine does not usually affect your ability to exercise. However, if you are taking it for pain, avoid strenuous activities that may worsen your condition. Consult your doctor before starting any new exercise routine.

🥗 Diet Recommendations

Stay well hydrated by drinking plenty of water.
Include fiber-rich foods to support liver health.
Limit processed and fried foods.
Avoid alcohol completely while taking this medicine.

💼 Impact on Daily Work & Life

This medicine generally does not affect your ability to drive or operate machinery. However, if you feel dizzy or drowsy, avoid these activities until you know how the medicine affects you.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your pain or fever persists beyond the recommended duration, if you experience any serious side effects, or if you develop signs of liver problems such as yellowing of the eyes or skin. Do not stop prescribed treatment without consulting your doctor.

📅 Long-Term Use Effects

Long-term use of this medicine at high doses can increase the risk of liver and kidney damage. It should only be used long-term under medical supervision. Regular monitoring of liver and kidney function may be advised. Do not use it continuously for more than 10 days for pain or 3 days for fever without consulting a doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve mobility.

Evidence: Well-established
Hot and cold compresses

May help relieve localized pain and inflammation.

Evidence: Established
Relaxation techniques

Can help manage chronic pain by reducing stress.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. It can be taken before or after vaccination if needed for pain or fever. However, consult your doctor if you have any concerns.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When travelling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust your dosing schedule to maintain the prescribed interval, but do not exceed the maximum daily dose. Check local regulations regarding carrying Paracetamol-containing medicines. Always keep it in your hand luggage if flying.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain due to osteoarthritis
Ramesh was prescribed this medicine for his knee pain. He took one tablet twice a day with meals. Within a week, his pain reduced significantly, and he could walk more comfortably. He was advised not to take more than the prescribed dose and to avoid alcohol. He also started physiotherapy, which further improved his mobility.
💡 Lesson: Taking this medicine with food and following the prescribed dose provides effective pain relief with minimal side effects. Combining with physiotherapy enhances outcomes.
👤 A 30-year-old woman with fever and body ache due to viral infection
Priya developed a high fever and severe body ache. Her doctor prescribed this medicine every 8 hours as needed. She took it for two days and her fever subsided. She was careful not to take any other Paracetamol-containing cold medicine simultaneously. She recovered fully without any side effects.
💡 Lesson: This medicine effectively reduces fever and body ache when taken as directed. Avoiding duplicate Paracetamol products prevents overdose.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain and reducing fever within 30 to 60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It can be taken with or without food, but taking it with food may reduce stomach upset.

Q: Is it safe during pregnancy?

A: Paracetamol is generally considered safe during pregnancy when taken at the lowest effective dose for the shortest duration. Consult your doctor before use.

Q: What should I do if I take too much?

A: Seek emergency medical help immediately, even if you feel fine, as overdose can cause delayed liver damage.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for acton-or tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Paracetamol is completely safe in any dose.
    Fact: Paracetamol can cause severe liver damage if taken in excess. Always follow the recommended dose.
  • Myth: Paracetamol is an anti-inflammatory medicine.
    Fact: Paracetamol has little to no anti-inflammatory effect. It is primarily an analgesic and antipyretic.
  • Myth: You can take Paracetamol with alcohol without any risk.
    Fact: Alcohol increases the risk of liver damage from Paracetamol. Avoid alcohol while taking this medicine.

🔄 Alternative Options

Generic Alternatives

  • Paracetamol 1000 mg tablets

Brand Alternatives

  • Dolo 650
  • Calpol 650
  • Crocin 650
  • Pacimol 650

📊 Comparison with Similar Medicines

[{"medicine":"Acton-OR Tablet SR","composition":"Paracetamol 300 mg + 700 mg","strength":"1000 mg","dosage_form":"Tablet","route":"Oral"},{"medicine":"Paracetamol 650 mg","composition":"Paracetamol 650 mg","strength":"650 mg","dosage_form":"Tablet","route":"Oral"},{"medicine":"Ibuprofen 400 mg + Paracetamol 500 mg","composition":"Ibuprofen + Paracetamol","strength":"400 mg + 500 mg","dosage_form":"Tablet","route":"Oral"}]

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