blomin 15iu injection - Bleomycin (15IU) medicine

Blomin 15IU Injection - Uses, Price, Side Effects

4.7 (10 reviews)

Bleomycin (15IU)

🏭 Venus Remedies Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is blomin 15iu injection used for?

Blomin 15IU Injection contains Bleomycin, an antineoplastic antibiotic used to treat various cancers including Hodgkin's lymphoma, testicular cancer, and squamous cell carcinomas. It works by inhibiting DNA synthesis and causing DNA strand breaks, thereby preventing cancer cell growth. It is administered intravenously or intramuscularly under medical supervision.

Generic Name: Bleomycin
Manufacturer: Venus Remedies Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 blomin 15iu injection Uses & Benefits

Hodgkin lymphoma, non-Hodgkin lymphoma, testicular cancer, squamous cell carcinoma of head and neck, cervical cancer, and malignant pleural effusion.

Off-label uses: Malignant effusions (pleurodesis), warts (intralesional), hemangiomas.

📋 Drug Information

Generic Name(s)	Bleomycin
Brand Name	Bleomycin Sulphate Injection
Manufacturer	Venus Remedies Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI NEOPLASTICS
Action Class	Alkaloids-cytotoxic agents
Route of Administration	Intravenous, intramuscular, subcutaneous, or intracavitary (pleural, peritoneal).
Storage	Store at 2-8°C; protect from light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntravenous or intramuscular administration; absorption is rapid and complete after IM injection.

DistributionWidely distributed; highest concentrations in skin, lungs, and lymph nodes; poor penetration into CNS.

Protein BindingApproximately 1% bound to plasma proteins.

MetabolismMetabolized primarily by hydrolase enzymes in various tissues, including liver and kidney.

Half-LifeBiphasic: initial half-life ~1.3 hours, terminal half-life ~9 hours (may be prolonged in renal impai

ExcretionRenal excretion; about 60-70% of dose excreted unchanged in urine.

BioavailabilityNot applicable (parenteral administration).

Onset of ActionRapid; within hours for antitumor effect.

Peak Plasma TimeImmediately after IV bolus; 30-60 minutes after IM injection.

Duration of ActionVariable; effects may persist for days to weeks.

How It Works

Causes DNA strand breaks via free radical generation, inhibiting DNA synthesis and cell division.

Mechanism Steps

1Bleomycin binds to DNA via intercalation and metal ion chelation.

2Forms a complex with Fe(II) and oxygen, generating reactive oxygen species (ROS).

3ROS cause single- and double-strand breaks in DNA.

💡 How to Take blomin 15iu injection

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of blomin 15iu injection

✅ Common Side Effects

Fever
Chills
Nausea
Vomiting
Alopecia
Mucositis
Skin hyperpigmentation
Raynaud phenomenon

🚨 Serious Side Effects

Pulmonary fibrosis
Pneumonitis
Hypersensitivity reactions
Myelosuppression (rare)
Hepatic veno-occlusive disease

⚠️ Rare Side Effects

Cardiotoxicity
Nephrotoxicity
Seizures
Scleroderma-like skin changes

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Cisplatin	Major	Increased risk of pulmonary toxicity
Radiation therapy	Major	Enhanced radiation-induced skin and lung toxicity
Live vaccines	Major	Risk of disseminated infection

🚨 Major Interactions

Cisplatin
Methotrexate
Vinca alkaloids
Radiation therapy

⚡ Moderate Interactions

Phenytoin
Digoxin
Warfarin

ℹ️ Minor Interactions

Acetaminophen
Cimetidine

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

No specific interaction; but alcohol may exacerbate hepatotoxicity.

🛡️ Safety & Warnings

Liver

Moderate

Kidney

Moderate

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to bleomycin; severe pulmonary disease; pregnancy.

📊 Monitoring Parameters

Pulmonary function tests (DLCO, chest X-ray), renal function, hepatic function, complete blood count.

🤱 Lactation Safety

Contraindicated; excreted in breast milk.

💊 Overdose Management

Supportive care; no specific antidote; monitor pulmonary function.

⏰ Missed Dose

Administer as soon as remembered; do not double dose; consult physician.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for blomin 15iu injection

View All

Alternative brands with exact same active ingredient (Bleomycin (15IU)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026