bleocin injection - Uses, Price, Side Effects & Substitutes
What is bleocin injection used for?
Bleomycin Sulphate Injection (Bleomycin) is used to treat ANTI NEOPLASTICS. It contains Bleomycin (15IU), which Causes DNA strand breaks via free radical generation, inhibiting DNA synthesis a. Always consult your doctor before use. Take as prescribed.
- Generic Name: Bleomycin
- Manufacturer: Khandelwal Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bleocin injection Uses & Benefits
Hodgkin lymphoma, non-Hodgkin lymphoma, testicular cancer, squamous cell carcinoma of head and neck, cervical cancer, and malignant pleural effusion.
Off-label uses: Malignant effusions (pleurodesis), warts (intralesional), hemangiomas.
๐ Drug Information
| Generic Name(s) | Bleomycin |
| Brand Name | Bleomycin Sulphate Injection |
| Manufacturer | Khandelwal Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Alkaloids-cytotoxic agents |
| Route of Administration | Intravenous, intramuscular, subcutaneous, or intracavitary (pleural, peritoneal). |
| Storage | Store at 2-8ยฐC; protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Causes DNA strand breaks via free radical generation, inhibiting DNA synthesis and cell division.
Mechanism Steps
๐ก How to Take bleocin injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bleocin injection
โ Common Side Effects
- Fever
- Chills
- Nausea
- Vomiting
- Alopecia
- Mucositis
- Skin hyperpigmentation
- Raynaud phenomenon
๐จ Serious Side Effects
- Pulmonary fibrosis
- Pneumonitis
- Hypersensitivity reactions
- Myelosuppression (rare)
- Hepatic veno-occlusive disease
โ ๏ธ Rare Side Effects
- Cardiotoxicity
- Nephrotoxicity
- Seizures
- Scleroderma-like skin changes
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Cisplatin | Major | Increased risk of pulmonary toxicity and renal impairment. |
| Methotrexate | Major | Increased risk of pulmonary toxicity. |
| Vinca alkaloids | Major | Increased risk of pulmonary toxicity. |
| Radiation therapy | Major | Enhanced radiation-induced pulmonary fibrosis. |
| Phenytoin | Moderate | Decreased phenytoin levels. |
| Digoxin | Moderate | Decreased digoxin absorption. |
| Warfarin | Moderate | Increased anticoagulant effect. |
| Acetaminophen | Minor | Possible decreased clearance of acetaminophen. |
| Cimetidine | Minor | Possible increased bleomycin toxicity. |
๐จ Major Interactions
- Cisplatin
- Methotrexate
- Vinca alkaloids
- Radiation therapy
โก Moderate Interactions
- Phenytoin
- Digoxin
- Warfarin
โน๏ธ Minor Interactions
- Acetaminophen
- Cimetidine
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
No specific interaction; but alcohol may exacerbate hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to bleomycin; severe pulmonary disease; pregnancy.
๐ Monitoring Parameters
Pulmonary function tests (DLCO, chest X-ray), renal function, hepatic function, complete blood count.
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk.
๐ Overdose Management
Supportive care; no specific antidote; monitor pulmonary function.
โฐ Missed Dose
Administer as soon as remembered; do not double dose; consult physician.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for bleocin injection
View AllAlternative brands with exact same active ingredient (Bleomycin (15IU)):
-
tumocin 15iu injectionNeon Laboratories Ltd โน505.95 29.5% CHEAPER
-
bleochem 15iu injectionBiochem Pharmaceutical Industries โน591.42 17.5% CHEAPER
-
bleocip 15iu injectionCipla Ltd โน616.65 14% CHEAPER
-
bleowel 15iu injectionGetwell Oncology Pvt Ltd โน637.00 11.2% CHEAPER
-
metbleo injectionMetta Life Sciences Private Limited โน650.00 9.4% CHEAPER
-
bleocel 15iu injectionCelon Laboratories Ltd โน653.00 9% CHEAPER
-
bleomycin sulphate injectionDabur India Ltd โน654.76 8.7% CHEAPER
-
lyoble injectionUnited Biotech Pvt Ltd โน681.63 5% CHEAPER
-
Naprobleo 15IU InjectionMiracalus Pharma Pvt Ltd โน800.00 11.5% COSTLIER
-
blomin 15iu injectionVenus Remedies Ltd โน850.00 18.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.