Aldigesic Injection: Complete Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is achnil sp tablet used for?
This medicine is a combination of aceclofenac and paracetamol used for short-term relief of pain and inflammation in conditions like arthritis, dental pain, and post-operative pain. It works by reducing prostaglandins. Take it with food, avoid alcohol, and do not exceed the prescribed dose.
- Generic Name: Aceclofenac + Paracetamol
- Manufacturer: Venus Remedies Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 achnil sp tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एसिटोक्लोफेनाक और पैरासिटामोल का संयोजन है, जिसका उपयोग दर्द और सूजन को कम करने के लिए किया जाता है। यह गठिया, दांत दर्द, ऑपरेशन के बाद के दर्द, और मांसपेशियों की चोट में प्रभावी है। यह शरीर में प्रोस्टाग्लैंडिन नामक रसायन को कम करके दर्द और सूजन को कम करती है। इसे डॉक्टर की सलाह के अनुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, एलर्जी, और किडनी या लीवर की समस्या हो सकती है। यदि आपको कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें। यदि आपको चक्कर आते हैं तो वाहन न चलाएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 achnil sp tablet Uses & Benefits
[{"condition":"Osteoarthritis","description":"Relieves pain and inflammation, improving joint mobility and function.","evidence":"Well-established"},{"condition":"Rheumatoid arthritis","description":"Reduces joint pain, swelling, and stiffness associated with rheumatoid arthritis.","evidence":"Well-established"},{"condition":"Ankylosing spondylitis","description":"Helps alleviate pain and stiffness in the spine and other joints.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides relief from acute dental pain, including post-extraction pain.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of moderate to severe post-surgical pain.","evidence":"Well-established"},{"condition":"Musculoskeletal injuries","description":"Reduces pain and swelling in sprains, strains, and other soft tissue injuries.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but evidence is limited.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"May be used off-label for menstrual pain, though not a first-line choice.","evidence":"Limited"}]
Primary treatment for: Pain and inflammation associated with musculoskeletal and joint disorders.
Also treats: Osteoarthritis, Rheumatoid arthritis, Ankylosing spondylitis, Dental pain, Post-operative pain, Musculoskeletal injuries
📋 Drug Information
| Generic Name(s) | Aceclofenac + Paracetamol |
| Brand Name | Aldigesic P |
| Manufacturer | Venus Remedies Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Analgesic/Antipyretic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Aceclofenac, an NSAID, inhibits the cyclooxygenase (COX) enzymes, particularly COX-2, leading to decreased synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Paracetamol, though its exact mechanism is not fully understood, primarily acts centrally to inhibit prostaglandin synthesis in the brain and may also modulate pain perception through other pathways. Together, they provide effective analgesia and anti-inflammatory action.
Mechanism Steps
💡 How to Take achnil sp tablet
Strength: Aceclofenac 100 mg + Paracetamol 325 mg tablet (typical).
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet containing aceclofenac 100 mg and paracetamol 325 mg, taken orally twice daily, preferably with meals. However, the dose and frequency must be individualized by a qualified clinician based on the indication, severity of pain, age, weight, renal and hepatic function, and response to treatment. Do not exceed the recommended dose. For short-term use only. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and renal impairment. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose reduction may be necessary. In severe renal impairment (creatinine clearance <30 mL/min), the use of this medicine is contraindicated. Consult a doctor for dose adjustment. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be necessary. In severe hepatic impairment, the use of this medicine is contraindicated. Consult a doctor for dose adjustment. |
| Maximum Daily Dose | The maximum daily dose should not exceed aceclofenac 200 mg and paracetamol 650 mg (or as prescribed). Do not exceed the recommended dose due to risk of liver toxicity and gastrointestinal bleeding. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of achnil sp tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| ACE inhibitors | Major | |
| Diuretics | Moderate | |
| Lithium | Moderate | |
| SSRIs | Moderate | |
| Antacids | Minor | |
| Cholestyramine | Minor |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- ACE inhibitors and ARBs
⚡ Moderate Interactions
- Diuretics (e.g., furosemide)
- Lithium
- SSRIs
- Antihypertensives (e.g., beta-blockers)
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver toxicity, especially with paracetamol. It can also enhance drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to aceclofenac, paracetamol, or any component of the formulation.","History of asthma, urticaria, or allergic reactions to NSAIDs.","Active peptic ulcer or gastrointestinal bleeding.","Severe renal impairment (e.g., creatinine clearance
⚠️ Warnings & Precautions
["Take with food to minimize gastrointestinal irritation.","Avoid alcohol consumption.","Use with caution in elderly patients due to increased risk of side effects.","Do not exceed the recommended dose of paracetamol to avoid liver toxicity.","Monitor for signs of gastrointestinal bleeding, especially with long-term use.","Use with caution in patients with cardiovascular risk factors.","Do not use for more than 7 days without medical advice.","Inform your doctor if you are taking blood thinners or other NSAIDs."]
🤱 Lactation Safety
This medicine may pass into breast milk in small amounts. It is generally not recommended during breastfeeding unless clearly needed and prescribed by a doctor. Consult your doctor to weigh the benefits and risks.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage due to paracetamol and gastrointestinal bleeding due to aceclofenac. Symptoms of overdose include nausea, vomiting, abdominal pain, drowsiness, and confusion. Seek immediate medical attention. Treatment includes gastric lavage, activated charcoal, and administration of N-acetylcysteine for paracetamol toxicity. Supportive care for NSAID toxicity may include management of bleeding and renal function.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not take more than the recommended dose or for longer than advised. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of gastrointestinal bleeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. Do not use this medicine if you are pregnant, especially in the last trimester, or breastfeeding without consulting your doctor. Keep out of reach of children. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, renal impairment, and cardiovascular events. Use with caution and monitor closely.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy if you are taking this medicine. It is not recommended during pregnancy, especially in the third trimester.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain management. Follow your surgeon's instructions and do not exceed the prescribed dose.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may increase pain while taking this medicine. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or if your pain persists beyond the prescribed duration. Do not stop abruptly without consulting your doctor if you have been on long-term therapy.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of gastrointestinal bleeding, ulcers, kidney impairment, liver toxicity, and cardiovascular events. Regular monitoring of liver and kidney function is recommended. Use the lowest effective dose for the shortest duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedMay be used for localized pain with fewer systemic side effects.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30-60 minutes after oral administration.
A: It is best taken with food or milk to reduce the risk of stomach upset.
A: Do not take with other NSAIDs or paracetamol-containing products without consulting your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for achnil sp tablet
View AllAlternative brands with exact same active ingredient:
-
temfix ace tabletNovartis India Ltd ₹7.03 86.6% CHEAPER
-
acemax p tabletAnglo-French Drugs & Industries Ltd ₹8.37 84.1% CHEAPER
-
muvel tabletCeras Pharmaceutical ₹18.53 64.7% CHEAPER
-
aldigesic injectionAlkem Laboratories Ltd ₹19.69 62.5% CHEAPER
-
deck p tabletOmega Remedies Pvt Ltd ₹24.01 54.3% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food to reduce stomach upset and risk of ulcers. - Myth: It is safe to take this medicine for long periods without monitoring.
Fact: Long-term use requires monitoring of liver, kidney, and gastrointestinal health. - Myth: This medicine is safe during pregnancy.
Fact: It is not recommended during pregnancy, especially in the third trimester, due to potential risks.
🔄 Alternative Options
Generic Alternatives
- Aceclofenac + Paracetamol generic tablets
Brand Alternatives
- Aldigesic
- Aceclo
- Zerodol-P
- Hifenac-P
- Acemiz-P