bleocare 15mg injection - Bleomycin (15mg) medicine

Bleocare 15mg Injection - Uses, Price, Side Effects

4.6 (9 reviews)
๐Ÿญ Criticare Laboratories Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 21, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 21, 2026

What is bleocare 15mg injection used for?

Bleocare 15mg Injection contains Bleomycin, a chemotherapy drug used to treat various cancers including Hodgkin's lymphoma, testicular cancer, and squamous cell carcinomas. It works by inhibiting DNA synthesis and causing DNA strand breaks, thereby preventing cancer cell growth. It is administered intravenously or intramuscularly under medical supervision.

  • Generic Name: Bleomycin
  • Manufacturer: Criticare Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š bleocare 15mg injection Uses & Benefits

Hodgkin lymphoma, non-Hodgkin lymphoma, testicular cancer, squamous cell carcinoma of head and neck, cervical cancer, and malignant pleural effusion.

Off-label uses: Malignant effusions (pleurodesis), warts (intralesional), hemangiomas.

๐Ÿ“‹ Drug Information

Generic Name(s)Bleomycin
Brand NameBleomycin Sulphate Injection
ManufacturerCriticare Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI NEOPLASTICS
Action ClassAlkaloids-cytotoxic agents
Route of AdministrationIntravenous, intramuscular, subcutaneous, or intracavitary (pleural, peritoneal).
StorageStore at 2-8ยฐC; protect from light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntravenous or intramuscular administration; absorption is rapid and complete after IM injection.
DistributionWidely distributed; highest concentrations in skin, lungs, and lymph nodes; poor penetration into CNS.
Protein BindingApproximately 1% bound to plasma proteins.
MetabolismMetabolized primarily by hydrolase enzymes in various tissues, including liver and kidney.
Half-LifeBiphasic: initial half-life ~1.3 hours, terminal half-life ~9 hours (may be prolonged in renal impai
ExcretionRenal excretion; about 60-70% of dose excreted unchanged in urine.
BioavailabilityNot applicable (parenteral administration).
Onset of ActionRapid; within hours for antitumor effect.
Peak Plasma TimeImmediately after IV bolus; 30-60 minutes after IM injection.
Duration of ActionVariable; effects may persist for days to weeks.

How It Works

Causes DNA strand breaks via free radical generation, inhibiting DNA synthesis and cell division.

Mechanism Steps

1Bleomycin binds to DNA via intercalation and metal ion chelation.
2Forms a complex with Fe(II) and oxygen, generating reactive oxygen species (ROS).
3ROS cause single- and double-strand breaks in DNA.

๐Ÿ’ก How to Take bleocare 15mg injection

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of bleocare 15mg injection

โœ… Common Side Effects

  • Fever
  • Chills
  • Nausea
  • Vomiting
  • Alopecia
  • Mucositis
  • Skin hyperpigmentation
  • Raynaud phenomenon

๐Ÿšจ Serious Side Effects

  • Pulmonary fibrosis
  • Pneumonitis
  • Hypersensitivity reactions
  • Myelosuppression (rare)
  • Hepatic veno-occlusive disease

โš ๏ธ Rare Side Effects

  • Cardiotoxicity
  • Nephrotoxicity
  • Seizures
  • Scleroderma-like skin changes

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Cisplatin Major Increased pulmonary toxicity
Radiation therapy Major Enhanced radiation-induced lung injury
Oxygen Moderate Increased risk of pulmonary fibrosis

๐Ÿšจ Major Interactions

  • Cisplatin
  • Methotrexate
  • Vinca alkaloids
  • Radiation therapy

โšก Moderate Interactions

  • Phenytoin
  • Digoxin
  • Warfarin

โ„น๏ธ Minor Interactions

  • Acetaminophen
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No specific interaction; but alcohol may exacerbate hepatotoxicity.

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Moderate
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to bleomycin; severe pulmonary disease; pregnancy.

๐Ÿ“Š Monitoring Parameters

Pulmonary function tests (DLCO, chest X-ray), renal function, hepatic function, complete blood count.

๐Ÿคฑ Lactation Safety

Contraindicated; excreted in breast milk.

๐Ÿ’Š Overdose Management

Supportive care; no specific antidote; monitor pulmonary function.

โฐ Missed Dose

Administer as soon as remembered; do not double dose; consult physician.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for bleocare 15mg injection

View All

Alternative brands with exact same active ingredient (Bleomycin (15mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

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