bleolem 15mg injection
What is bleolem 15mg injection used for?
Bleomycin Sulphate Injection (Bleomycin) is used to treat ANTI NEOPLASTICS. It contains Bleomycin (15mg), which Causes DNA strand breaks via free radical generation, inhibiting DNA synthesis a. Always consult your doctor before use. Take as prescribed.
- Generic Name: Bleomycin
- Manufacturer: Lemery
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bleolem 15mg injection Uses & Benefits
Hodgkin lymphoma, non-Hodgkin lymphoma, testicular cancer, squamous cell carcinoma of head and neck, cervical cancer, and malignant pleural effusion.
Off-label uses: Malignant effusions (pleurodesis), warts (intralesional), hemangiomas.
๐ Drug Information
| Generic Name(s) | Bleomycin |
| Brand Name | Bleomycin Sulphate Injection |
| Manufacturer | Lemery |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Alkaloids-cytotoxic agents |
| Route of Administration | Intravenous, intramuscular, subcutaneous, or intracavitary (pleural, peritoneal). |
| Storage | Store at 2-8ยฐC; protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Causes DNA strand breaks via free radical generation, inhibiting DNA synthesis and cell division.
Mechanism Steps
๐ก How to Take bleolem 15mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of bleolem 15mg injection
โ Common Side Effects
- Fever
- Chills
- Nausea
- Vomiting
- Alopecia
- Mucositis
- Skin hyperpigmentation
- Raynaud phenomenon
๐จ Serious Side Effects
- Pulmonary fibrosis
- Pneumonitis
- Hypersensitivity reactions
- Myelosuppression (rare)
- Hepatic veno-occlusive disease
โ ๏ธ Rare Side Effects
- Cardiotoxicity
- Nephrotoxicity
- Seizures
- Scleroderma-like skin changes
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Cisplatin | Major | Increased risk of pulmonary toxicity and renal impairment. |
| Methotrexate | Major | Increased risk of pulmonary toxicity. |
| Vinca alkaloids | Major | Increased risk of pulmonary toxicity. |
| Radiation therapy | Major | Enhanced radiation-induced pulmonary fibrosis. |
| Phenytoin | Moderate | Decreased phenytoin levels. |
| Digoxin | Moderate | Decreased digoxin absorption. |
| Warfarin | Moderate | Increased anticoagulant effect. |
| Acetaminophen | Minor | Possible decreased clearance of acetaminophen. |
| Cimetidine | Minor | Possible increased bleomycin toxicity. |
๐จ Major Interactions
- Cisplatin
- Methotrexate
- Vinca alkaloids
- Radiation therapy
โก Moderate Interactions
- Phenytoin
- Digoxin
- Warfarin
โน๏ธ Minor Interactions
- Acetaminophen
- Cimetidine
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
No specific interaction; but alcohol may exacerbate hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to bleomycin; severe pulmonary disease; pregnancy.
๐ Monitoring Parameters
Pulmonary function tests (DLCO, chest X-ray), renal function, hepatic function, complete blood count.
๐คฑ Lactation Safety
Contraindicated; excreted in breast milk.
๐ Overdose Management
Supportive care; no specific antidote; monitor pulmonary function.
โฐ Missed Dose
Administer as soon as remembered; do not double dose; consult physician.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for bleolem 15mg injection
View AllAlternative brands with exact same active ingredient (Bleomycin (15mg)):
-
bledmax 15mg injectionMax India Ltd โน950.00 4.5% CHEAPER
-
bleocare 15mg injectionCriticare Laboratories Pvt Ltd โน985.00 1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.
Found this to be a helpful product. Good results.
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.