Benorgan 5mg Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or shortness of breath
- Severe drowsiness or unresponsiveness
- Seizures or convulsions
- Irregular or rapid heartbeat
- Severe allergic reaction (swelling of face, lips, tongue, or throat)
- Yellowing of skin or eyes (jaundice)
- Unusual bleeding or bruising
- Severe abdominal pain or persistent vomiting
If experiencing severe symptoms, call emergency services immediately.
What is benorgan 5mg syrup used for?
This medicine is an antihistamine syrup containing promethazine 5mg. It is used to treat allergies, nausea, vomiting, motion sickness, and short-term insomnia. It works by blocking histamine and depressing the central nervous system. It is not for children under 2 years.
- Generic Name: Promethazine
- Manufacturer: Benmed Pharmaceuticals
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 benorgan 5mg syrup के बारे में (Hindi Summary)
उपयोग: यह दवा प्रोमेथाज़ीन 5mg सिरप है, जिसका उपयोग एलर्जी, जैसे नाक बहना, छींक आना, खुजली और पित्ती के इलाज के लिए किया जाता है। यह मतली, उल्टी और मोशन सिकनेस को रोकने और इलाज करने में भी प्रभावी है। इसके अलावा, यह अनिद्रा (नींद न आने) के अल्पकालिक उपचार के लिए भी इस्तेमाल किया जाता है। यह दवा दिमाग को शांत करके और हिस्टामिन को रोककर काम करती है। यह 2 साल से छोटे बच्चों के लिए नहीं है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, धुंधली दृष्टि, मुँह सूखना और कब्ज शामिल हैं। गंभीर दुष्प्रभावों में अत्यधिक नींद, सांस लेने में कठिनाई, दौरे, अनियमित दिल की धड़कन और पेशाब में रुकावट हो सकती है। यदि आपको एलर्जी की प्रतिक्रिया, जैसे चकत्ते, सूजन या सांस लेने में तकलीफ हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा लेने के दौरान गाड़ी चलाने या मशीनरी चलाने से बचें क्योंकि यह नींद और चक्कर का कारण बन सकती है। शराब और अन्य नींद लाने वाली दवाओं के साथ इसका सेवन न करें। 2 साल से छोटे बच्चों को यह दवा न दें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। दवा को डॉक्टर के बताए समय तक ही लें। इसे बच्चों की पहुंच से दूर रखें।
💊 benorgan 5mg syrup Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, and itching associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Urticaria","description":"Reduces itching and hives due to allergic reactions.","evidence":"Well-established"},{"condition":"Nausea and vomiting","description":"Prevents and treats nausea and vomiting, including motion sickness and post-operative nausea.","evidence":"Well-established"},{"condition":"Motion sickness","description":"Prevents nausea, vomiting, and dizziness associated with travel.","evidence":"Well-established"},{"condition":"Insomnia","description":"Short-term management of insomnia due to its sedative properties.","evidence":"Well-established"},{"condition":"Pre-operative sedation","description":"Used to produce sedation and reduce anxiety before surgery.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Migraine","description":"Sometimes used to treat migraine headaches due to its sedative and antiemetic effects.","evidence":"Limited"},{"condition":"Anxiety","description":"Occasionally used for short-term relief of anxiety, but not a first-line treatment.","evidence":"Limited"}]
Primary treatment for: Allergic rhinitis
Also treats: Urticaria, Nausea and vomiting, Motion sickness, Insomnia
📋 Drug Information
| Generic Name(s) | Promethazine |
| Brand Name | Avomine |
| Manufacturer | Benmed Pharmaceuticals |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | H1 Antihistaminics (First Generation) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep the bottle tightly closed. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Promethazine is a phenothiazine derivative that acts as a potent antihistamine (H1 receptor antagonist). It also has anticholinergic, antiemetic, and sedative properties. It works by blocking histamine H1 receptors in the gastrointestinal tract, blood vessels, and respiratory tract, thereby reducing allergic symptoms. Its antiemetic effect is due to inhibition of the chemoreceptor trigger zone in the medulla oblongata. The sedative effect is mediated through central H1 receptor blockade and possibly other mechanisms.
Mechanism Steps
💡 How to Take benorgan 5mg syrup
Strength: Syrup, 5 mg per 5 mL
Dosage Information
| Adult Dosage | The dosage of this medicine must be individualized by a qualified clinician based on the indication, age, weight, and renal and hepatic function. For allergic conditions, the usual adult dose is 12.5 mg to 25 mg taken before meals or at bedtime. For nausea and vomiting, 12.5 mg to 25 mg every 4 to 6 hours as needed. For motion sickness, 25 mg taken 30 to 60 minutes before travel. For insomnia, 25 mg at bedtime. Do not exceed 150 mg per day. This is for educational purposes only; follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is contraindicated in children under 2 years of age due to the risk of severe respiratory depression. |
| Elderly Dosage | Elderly patients are more sensitive to the sedative and anticholinergic effects of this medicine. Start with a lower dose and titrate slowly. Use with caution due to increased risk of confusion, falls, and urinary retention. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be necessary in patients with renal impairment. Consult your doctor for appropriate dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be required. Consult your doctor for appropriate dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 150 mg for adults. Do not exceed this dose without medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of benorgan 5mg syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | |
| Opioids | Major | |
| Benzodiazepines | Major | |
| MAOIs | Major | |
| Tricyclic antidepressants | Moderate | |
| Epinephrine | Moderate | |
| Levodopa | Moderate | |
| Antihypertensives | Moderate | |
| Antacids | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- CNS depressants (e.g., alcohol, opioids, benzodiazepines, barbiturates)
- Monoamine oxidase inhibitors (MAOIs)
- Anticholinergic drugs (e.g., atropine, tricyclic antidepressants)
⚡ Moderate Interactions
- Epinephrine
- Levodopa
- Antihypertensive drugs
🍷 Alcohol Interaction
Alcohol should be strictly avoided while taking this medicine. The combination can cause severe drowsiness, dizziness, respiratory depression, and impaired motor skills, increasing the risk of accidents and falls.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Children under 2 years of age","Known hypersensitivity to promethazine or other phenothiazines","Comatose patients","Patients with severe respiratory depression or asthma","Patients with sleep apnea","Patients with severe liver disease","Patients with narrow-angle glaucoma","Patients with prostatic hypertrophy or bladder neck obstruction","Patients with bone marrow depression"]
⚠️ Warnings & Precautions
["May cause severe drowsiness; avoid driving or operating machinery.","Do not use in children under 2 years due to risk of fatal respiratory depression.","Use with caution in elderly patients; increased risk of confusion, falls, and anticholinergic effects.","Avoid alcohol and other CNS depressants.","May lower seizure threshold; use with caution in patients with seizure disorders.","May cause photosensitivity; use sunscreen.","Do not use for longer than prescribed without medical supervision.","Inform your doctor if you have liver, kidney, or heart disease.","May interfere with allergy skin testing; discontinue 3 days before testing."]
🤱 Lactation Safety
Promethazine is excreted in breast milk and may cause drowsiness or respiratory depression in the nursing infant. Breastfeeding is not recommended while taking this medicine. Consult your doctor for alternative options.
💊 Overdose Management
Overdose of promethazine can cause severe drowsiness, coma, seizures, respiratory depression, and cardiac arrhythmias. If overdose is suspected, seek emergency medical attention immediately. Treatment is supportive and symptomatic, including airway management, monitoring of vital signs, and administration of activated charcoal if within 1-2 hours of ingestion. There is no specific antidote. Do not induce vomiting unless instructed by a healthcare professional.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
This medicine can cause significant drowsiness and impair your ability to drive or operate machinery. Avoid alcohol and other central nervous system depressants while taking this medicine, as they can increase sedation. Do not use this medicine for children under 2 years of age. Use with caution in the elderly due to increased risk of confusion and falls. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not take this medicine for longer than prescribed without consulting your doctor. Keep out of reach of children. Store at room temperature away from light and moisture.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and anticholinergic effects of this medicine. They are at increased risk of confusion, falls, urinary retention, and constipation. Use with caution and start with a lower dose. Regular monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed. Discuss alternative treatments that may be safer for you and your baby.
🏥 Post-Surgery Considerations
This medicine may be used for sedation before or after surgery. However, it can increase the risk of respiratory depression, especially when combined with other sedatives or anesthetics. Inform your surgeon and anesthesiologist if you are taking this medicine.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it can cause dry mouth and increase the risk of dental caries. It may also interact with sedatives used during dental procedures. Your dentist may recommend adjusting your dose or taking precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness and dizziness, which may impair your coordination and balance. Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you. If you exercise, do so with caution and stay hydrated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can significantly impact your ability to work, especially if your job requires alertness, driving, or operating machinery. It can cause drowsiness, dizziness, and blurred vision. Discuss with your employer or doctor about temporary work adjustments if needed.
🛑 When to Stop This Medicine
Do not stop taking this medicine abruptly without consulting your doctor, especially if you have been using it for a long time. Your doctor may gradually reduce the dose to prevent withdrawal symptoms. If you experience severe side effects, seek medical advice immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to tolerance, dependence, and withdrawal symptoms. It can also cause tardive dyskinesia, a movement disorder, and other extrapyramidal symptoms. Regular monitoring by a healthcare professional is recommended. Do not use for prolonged periods without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For allergies, non-sedating antihistamines like loratadine or cetirizine may be used to avoid drowsiness.
Evidence: Well-establishedCognitive behavioral therapy for insomnia (CBT-I) is a first-line treatment for chronic insomnia.
Evidence: Well-establishedFor motion sickness, acupressure bands may help reduce nausea without medication.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may interfere with allergy skin testing. Discontinue use at least 3 days before scheduled allergy testing. There are no known interactions with vaccines, but consult your doctor before vaccination if you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container with cap tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it in your carry-on luggage to avoid extreme temperatures. If crossing time zones, adjust dosing times gradually under medical guidance. Check local customs regulations regarding controlled substances, as some countries may have restrictions.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 20 to 60 minutes after oral administration.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a small amount of food or milk.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: No, this medicine can cause significant drowsiness and impair your ability to drive or operate machinery. Avoid driving until you know how it affects you.
A: This medicine is contraindicated in children under 2 years of age. For older children, consult a pediatrician for appropriate dosing.
A: Consult your doctor before taking this medicine if you are pregnant or planning to become pregnant. It should be used only if clearly needed.
A: This medicine passes into breast milk and may cause drowsiness in the infant. Breastfeeding is not recommended. Consult your doctor for alternatives.
A: Store at room temperature between 15°C and 30°C, away from light and moisture. Keep the bottle tightly closed and out of reach of children.
A: Common side effects include drowsiness, dizziness, dry mouth, blurred vision, and constipation. These are usually mild and temporary.
A: No, alcohol should be strictly avoided as it can cause severe drowsiness, respiratory depression, and other serious effects.
🤔 Common Patient Concerns
🔄 Substitutes for benorgan 5mg syrup
View AllAlternative brands with exact same active ingredient:
-
emigan injectionBiochem Pharmaceutical Industries ₹6.47 70% CHEAPER
-
histazine 5mg syrupAngel Laboratories Pvt Ltd ₹15.94 26.1% CHEAPER
-
k promex 5mg syrupKumayun Drugs Pvt Ltd ₹15.94 26.1% CHEAPER
-
largan syrupSouthshourne Corporation India ₹22.50 4.4% COSTLIER
-
progan syrupThe Pharmed Research Lab Pvt Ltd ₹23.34 8.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe for children under 2 years.
Fact: This medicine is contraindicated in children under 2 years due to the risk of fatal respiratory depression. - Myth: This medicine is not habit-forming.
Fact: This medicine has a low potential for dependence, but prolonged use can lead to tolerance and psychological dependence. - Myth: You can drink alcohol while taking this medicine.
Fact: Alcohol should be strictly avoided as it can cause severe drowsiness and respiratory depression.
🔄 Alternative Options
Generic Alternatives
- Promethazine hydrochloride syrup
Brand Alternatives
- Phenergan
- Promethegan
- Phenadoz