Admol 125mg Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing, wheezing, or swelling of the face, lips, tongue, or throat
- Severe drowsiness, confusion, or inability to stay awake
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain
- Unusual bleeding or bruising, or signs of infection such as fever and sore throat
- Abnormal muscle movements, stiffness, tremors, or difficulty speaking
- Seizures or loss of consciousness
- Severe skin rash with blisters or peeling
If experiencing severe symptoms, call emergency services immediately.
What is Fenaplus Syrup used for?
This medicine is a syrup containing paracetamol 125 mg and promethazine 5 mg per 5 mL. It is used for pain, fever, nausea, and allergic symptoms with restlessness. It causes drowsiness and must not be given to children under 2 years. Use only as prescribed.
- Generic Name: Paracetamol (125mg) + Promethazine (5mg)
- Manufacturer: Leeford Healthcare Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Fenaplus Syrup के बारे में (Hindi Summary)
उपयोग: यह दवा पैरासिटामोल और प्रोमेथाज़ीन का संयोजन है, जिसका उपयोग हल्के से मध्यम दर्द, बुखार, जी मिचलाना, उल्टी और एलर्जी के लक्षणों के इलाज के लिए किया जाता है, खासकर जब बेचैनी या नींद न आने की समस्या भी हो। यह सिरप के रूप में आती है और इसका सेवन मुँह से किया जाता है। यह दवा बच्चों में 2 वर्ष से कम उम्र में नहीं दी जानी चाहिए। इसका उपयोग केवल डॉक्टर की सलाह पर ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, सुस्ती, चक्कर आना, धुंधली दृष्टि, मुँह सूखना और कब्ज शामिल हैं। कभी-कभी बच्चों में उल्टा प्रभाव भी देखा जा सकता है, जैसे बहुत अधिक बेचैनी। गंभीर दुष्प्रभावों में एलर्जी, रक्त विकार, यकृत की क्षति और त्वचा पर गंभीर प्रतिक्रियाएँ शामिल हो सकती हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का सेवन केवल डॉक्टर की सलाह पर करें और निर्धारित मात्रा से अधिक न लें। यह दवा नींद और सुस्ती बढ़ाती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब का सेवन न करें। 2 वर्ष से कम उम्र के बच्चों को यह दवा न दें। अन्य पैरासिटामोल युक्त दवाओं के साथ इसका सेवन न करें। दवा को बच्चों की पहुँच से दूर रखें।
💊 Fenaplus Syrup Uses & Benefits
[{"condition":"Mild to moderate pain with fever","description":"Used to reduce pain and lower fever in conditions such as viral upper respiratory infections, teething, or post-vaccination discomfort, especially when the patient is restless.","evidence":"Well-established for paracetamol; promethazine adds sedation and antiemetic effect."},{"condition":"Nausea and vomiting","description":"Promethazine helps control nausea and vomiting, while paracetamol addresses any accompanying pain or fever.","evidence":"Well-established for promethazine as an antiemetic."},{"condition":"Allergic conditions with restlessness","description":"May be used for allergic rhinitis, urticaria, or itching when sedation is acceptable or desirable.","evidence":"Well-established for promethazine as an antihistamine."},{"condition":"Pre-operative or post-operative sedation and antiemesis","description":"Sometimes used in hospital settings for sedation and to prevent nausea and vomiting after surgery.","evidence":"Established in clinical practice for promethazine."}]
Off-label uses: [{"condition":"Short-term management of insomnia","description":"Promethazine is sometimes used off-label for its sedative effect in adults, but this is not a first-line treatment.","evidence":"Limited"},{"condition":"Motion sickness","description":"Promethazine has antiemetic and sedative properties that may help motion sickness, though other agents are often preferred.","evidence":"Limited"}]
Primary treatment for: Symptomatic relief of pain, fever, nausea, and allergic conditions with restlessness
Also treats: Viral upper respiratory tract infection, Post-vaccination fever and discomfort, Allergic rhinitis, Urticaria, Motion sickness
📋 Drug Information
| Generic Name(s) | Paracetamol (125mg) + Promethazine (5mg) |
| Brand Name | Fenaplus Syrup |
| Manufacturer | Leeford Healthcare Ltd |
| Packaging / Form | bottle of 60 ml Syrup (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep the bottle tightly closed and out of reach of children. |
| Shelf Life | Refer to the expiry date printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Paracetamol reduces pain and fever mainly through central actions that decrease prostaglandin synthesis in the brain and may involve descending serotonergic pathways. Promethazine is a first-generation antihistamine that competitively blocks histamine H1 receptors, which reduces allergic symptoms and produces sedation. Promethazine also has anticholinergic and antiemetic effects, likely through blockade of muscarinic receptors and dopamine receptors in the chemoreceptor trigger zone. The combination provides pain and fever relief along with sedation and nausea control.
Mechanism Steps
💡 How to Take Fenaplus Syrup
Strength: Each 5 mL of syrup contains paracetamol 125 mg and promethazine 5 mg.
Dosage Information
| Adult Dosage | The adult dose of this medicine is not fixed and must be individualized by a qualified clinician based on the indication, age, weight, liver and kidney function, and other medicines being taken. In general, paracetamol-containing products are dosed every 4 to 6 hours as needed, but the total daily paracetamol dose should not exceed 4 grams in adults unless otherwise directed. Promethazine adds sedation, so the smallest effective dose should be used for the shortest necessary duration. Do not self-medicate with this combination product. |
| Pediatric Dosage | Pediatric dosing is not established from available information. This medicine should not be used in children under 2 years of age. For older children, the dose must be determined by a pediatrician based on weight and clinical condition. Do not use adult doses in children. |
| Elderly Dosage | Elderly patients are more sensitive to the sedative, anticholinergic, and hypotensive effects of promethazine. Use the lowest effective dose and monitor for confusion, falls, urinary retention, and excessive drowsiness. Paracetamol dose should be adjusted if liver or kidney function is impaired. |
| Renal Impairment | Dose adjustment may be required in patients with moderate to severe kidney impairment. Paracetamol and promethazine clearance may be reduced. Consult a clinician for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with liver disease. Paracetamol dose should be reduced or avoided in severe hepatic impairment because of the risk of liver injury. Promethazine is metabolized by the liver and may accumulate. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose depends on the clinical situation and must be determined by a qualified clinician. For paracetamol, the usual adult maximum is 4 grams per day from all sources. Promethazine maximum daily dose varies by indication and age. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Fenaplus Syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Opioid painkillers | Major | |
| Benzodiazepines | Major | |
| Alcohol | Major | |
| MAOIs | Major | |
| Warfarin | Moderate | |
| Tricyclic antidepressants | Moderate | |
| Carbamazepine | Moderate | |
| Levodopa | Moderate | |
| Antacids | Minor | |
| Activated charcoal | Minor |
🚨 Major Interactions
- Other central nervous system depressants (opioids, benzodiazepines, alcohol, sleeping pills)
- Monoamine oxidase inhibitors (MAOIs)
- Warfarin
⚡ Moderate Interactions
- Anticholinergic drugs (e.g., atropine, tricyclic antidepressants, some antipsychotics)
- Carbamazepine, phenytoin, rifampicin, and other enzyme inducers
- Levodopa
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol increases the sedative effects of promethazine and raises the risk of liver damage from paracetamol, especially with regular or high-dose use.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Children under 2 years of age","Known hypersensitivity to paracetamol, promethazine, or any component of the formulation","Severe liver disease or active liver failure","Severe kidney disease without appropriate dose adjustment","Narrow-angle glaucoma","Urinary retention or prostatic hypertrophy with obstruction","Severe central nervous system depression or coma","Use with MAOIs or within 14 days of stopping an MAOI"]
⚠️ Warnings & Precautions
["May cause marked drowsiness; avoid driving and operating machinery until you know how it affects you.","Do not use in children under 2 years because of the risk of severe respiratory depression.","Use with caution in elderly patients, who are more sensitive to sedation, confusion, and anticholinergic effects.","Avoid alcohol and other central nervous system depressants.","Do not exceed the recommended dose of paracetamol; overdose can cause fatal liver injury.","Check other medicines for paracetamol content to avoid accidental overdose.","Use with caution in patients with asthma, epilepsy, glaucoma, or difficulty urinating.","Promethazine may cause photosensitivity; protect skin from sunlight.","Stop and seek medical advice if you develop abnormal muscle movements, high fever, or severe skin reactions."]
🤱 Lactation Safety
Paracetamol is considered compatible with breastfeeding in usual doses. Promethazine passes into breast milk and may cause drowsiness or irritability in the infant, so it should be used only if prescribed by a clinician, who may recommend monitoring the baby for sedation.
💊 Overdose Management
Overdose of this medicine can be serious because of paracetamol-induced liver injury and promethazine-induced sedation, respiratory depression, and anticholinergic effects. Seek emergency medical care immediately, even if there are no symptoms at first. Do not wait for symptoms to appear. Treatment may include activated charcoal if given early, N-acetylcysteine for paracetamol toxicity, and supportive care for promethazine effects. Bring the medicine bottle or packaging to the hospital.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember if it is less than half the dosing interval away. If more than half the dosing interval has passed, skip the missed dose and continue with the next scheduled dose. Do not double the dose to catch up.
Additional Safety Advice
Use this medicine only under the guidance of a qualified healthcare professional, and never exceed the prescribed dose. Because promethazine causes marked drowsiness, avoid driving, operating heavy machinery, or performing activities that require full alertness until you know how this medicine affects you. Do not give this medicine to children under two years of age, and use extra caution in children and elderly patients because they are more sensitive to sedation and movement-related side effects. Avoid alcohol and other medicines that make you sleepy, such as opioid painkillers, sleeping pills, or anxiety medicines, unless your doctor specifically approves them. Check all other medicines you take for paracetamol content to prevent accidental overdose, which can cause serious liver damage. Tell your doctor if you have liver or kidney disease, asthma, glaucoma, an enlarged prostate, difficulty urinating, epilepsy, or a blood disorder. Keep the bottle tightly closed and out of reach of children, and measure doses with a proper measuring device rather than a household spoon.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to experience drowsiness, confusion, dizziness, falls, urinary retention, and constipation from promethazine. Use the lowest effective dose and monitor closely. Paracetamol dose should be adjusted in liver or kidney impairment.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy or are pregnant, consult your doctor before using this medicine. Paracetamol is generally preferred for short-term pain and fever, but promethazine should be used only if clearly needed. Discuss all medicines with your obstetrician.
🏥 Post-Surgery Considerations
This medicine may be used after surgery for pain, nausea, and sedation, but it should be prescribed by the surgical team. It can add to the sedative effects of anesthesia and pain medicines, so monitoring is required.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. Promethazine can cause dry mouth and drowsiness, and it may interact with sedatives used during dental work.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that require balance and coordination while taking this medicine because of the risk of drowsiness and dizziness. Light activity such as walking may be fine if you feel well, but stop if you feel dizzy or weak.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause significant drowsiness and reduced alertness, which may affect your ability to work, drive, or operate machinery. It is best to avoid these activities until you know how the medicine affects you. If your job requires alertness, discuss with your doctor whether a different medicine or timing is better.
🛑 When to Stop This Medicine
Stop this medicine when your symptoms improve or as directed by your doctor. Do not stop suddenly if you have been taking it regularly for a long time without medical advice. Seek immediate medical attention if you develop any red-flag symptoms. Do not use it for longer than recommended without consulting a clinician.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended without medical supervision. Prolonged use of promethazine can lead to tolerance, dependence, and persistent drowsiness or movement disorders. Regular paracetamol use at high doses can increase the risk of liver and kidney problems. If long-term therapy is needed, your doctor should monitor liver and kidney function, blood counts, and for any signs of blood disorders or movement abnormalities.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For pain and fever without nausea or allergy, paracetamol alone may be sufficient and avoids sedation.
Evidence: Well-establishedSmall sips of clear fluids, ginger, and rest can help mild nausea.
Evidence: LimitedIdentifying and avoiding allergens can reduce the need for antihistamines.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may be used to relieve fever and discomfort after vaccination, but it should not be given routinely before vaccination without medical advice. Follow your doctor's instructions regarding timing and dose.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified on the label
✅ DO
Keep in the original container with the cap tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of the prescription or a letter from your doctor, especially for international travel, because promethazine is a controlled or prescription-only medicine in some countries. Store it at room temperature and protect it from extreme heat or direct sunlight. If crossing time zones, follow the dosing schedule recommended by your doctor; do not double doses to adjust for time changes. Keep the bottle in your carry-on luggage if you need it during the flight, and declare it if required by customs.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Paracetamol starts relieving pain and fever within 30 to 60 minutes, while promethazine sedation and antiemetic effects begin within 20 to 60 minutes.
A: Paracetamol effects last about 4 to 6 hours. Promethazine effects may last longer, up to 12 hours or more.
A: Do not take additional paracetamol-containing products without medical advice because of the risk of liver injury. Other painkillers may interact or add to sedation.
A: It is not safe for children under 2 years. For older children, the dose must be determined by a pediatrician.
A: This medicine is usually used short-term. You can stop when symptoms improve, but consult your doctor if you have been using it regularly or for a long time.
🤔 Common Patient Concerns
🔄 Substitutes for Fenaplus Syrup
View AllAlternative brands with exact same active ingredient:
-
vomica syrupParex Pharmaceuticals Pvt Ltd ₹16.88 22.8% COSTLIER
-
paracee plus syrupV.S. Healthcare Ltd ₹19.59 42.5% COSTLIER
-
promol plus syrupHealing Touch Pharmaceuticals Pvt Ltd ₹19.90 44.7% COSTLIER
-
Tymol P SuspensionRaddison Health Care Pvt Ltd ₹20.00 45.5% COSTLIER
-
promit p suspensionMits Healthcare Pvt Ltd ₹22.50 63.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe for all ages.
Fact: It is not safe for children under 2 years and requires caution in elderly patients. - Myth: More medicine means faster relief.
Fact: Taking more than the recommended dose can cause serious liver damage and severe sedation. - Myth: It is safe to take with alcohol.
Fact: Alcohol increases sedation and the risk of liver injury. - Myth: It can be used for any type of pain.
Fact: It is intended for specific uses and should not replace appropriate treatment for severe or persistent pain.
🔄 Alternative Options
Generic Alternatives
- Paracetamol 125 mg + Promethazine 5 mg per 5 mL syrup