bendashil 100mg injection - Bendamustine (100mg) medicine

bendashil 100mg injection

4.6 (17 reviews)
๐Ÿญ Shilpa Medicare Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is bendashil 100mg injection used for?

Adben 100mg Injection (Bendamustine) is used to treat ANTI NEOPLASTICS. It contains Bendamustine (100mg), which Alkylating agent that forms cross-links between DNA strands, inhibiting DNA synt. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Bendamustine
  • Manufacturer: Shilpa Medicare Ltd
  • Form: Allopathy
  • Pregnancy Category: D
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š bendashil 100mg injection Uses & Benefits

Chronic lymphocytic leukemia (CLL), indolent B-cell non-Hodgkin lymphoma (NHL), multiple myeloma.

Off-label uses: Hodgkin lymphoma, T-cell lymphoma, breast cancer.

๐Ÿ“‹ Drug Information

Generic Name(s)Bendamustine
Brand NameAdben 100mg Injection
ManufacturerShilpa Medicare Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI NEOPLASTICS
Action ClassAlkylating agent
Route of AdministrationIntravenous infusion.
StorageStore at 20-25ยฐC; protect from light; reconstituted solution stable for 24 hours at room temperature.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntravenous administration results in complete bioavailability.
DistributionWidely distributed; volume of distribution approximately 20-25 L.
Protein BindingApproximately 94-96% bound to plasma proteins.
MetabolismHepatic metabolism via CYP1A2 to active metabolites (gamma-hydroxybendamustine and N-desmethylbendamustine).
Half-LifeApproximately 40 minutes (parent drug); active metabolites have longer half-lives.
ExcretionPrimarily fecal (approximately 90%) and renal (approximately 10%).
Bioavailability100% (intravenous).
Onset of ActionRapid; within hours.
Peak Plasma TimeEnd of infusion.
Duration of ActionVariable; depends on regimen.

How It Works

Alkylating agent that forms cross-links between DNA strands, inhibiting DNA synthesis and repair.

Mechanism Steps

1Bendamustine undergoes hydrolysis to form active metabolites.
2Active metabolites alkylate DNA at guanine N7 position.
3Cross-linking of DNA strands inhibits replication and transcription.

๐Ÿ’ก How to Take bendashil 100mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of bendashil 100mg injection

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Fatigue
  • Fever
  • Myelosuppression (neutropenia, thrombocytopenia, anemia)

๐Ÿšจ Serious Side Effects

  • Severe myelosuppression
  • Infection
  • Tumor lysis syndrome
  • Stevens-Johnson syndrome
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Interstitial pneumonitis
  • Cardiac arrhythmias
  • Secondary malignancies

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Ciprofloxacin Major Increased bendamustine exposure
Warfarin Moderate Increased bleeding risk
Live vaccines Moderate Risk of disseminated infection

๐Ÿšจ Major Interactions

  • CYP1A2 inhibitors (e.g., ciprofloxacin, fluvoxamine)
  • CYP1A2 inducers (e.g., carbamazepine, rifampin)

โšก Moderate Interactions

  • Live vaccines
  • Anticoagulants (e.g., warfarin)

โ„น๏ธ Minor Interactions

  • Acetaminophen
  • Allopurinol

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

Avoid alcohol due to potential hepatotoxicity.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to bendamustine; severe bone marrow suppression; active infection.

๐Ÿ“Š Monitoring Parameters

Complete blood count (CBC), liver function tests, renal function, serum electrolytes.

๐Ÿคฑ Lactation Safety

Not recommended; discontinue breastfeeding.

๐Ÿ’Š Overdose Management

Supportive care; monitor for myelosuppression; no specific antidote.

โฐ Missed Dose

Do not double dose; consult physician if dose missed.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for bendashil 100mg injection

View All

Alternative brands with exact same active ingredient (Bendamustine (100mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Certified Buyer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

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