axitan 1 tablet - Lorazepam (1mg) medicine

Axitan 1 Tablet (Lorazepam 1mg) - Uses, Price, Side Effects

4.6 (19 reviews)

Lorazepam (1mg)

🏭 Biologic Psychotropics India Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is axitan 1 tablet used for?

Axitan 1 Tablet contains Lorazepam 1mg, a benzodiazepine used to treat anxiety disorders and insomnia. It works by enhancing the effect of GABA, a natural chemical in the brain that promotes calmness and relaxation. It is typically taken twice daily as directed by a doctor.

Generic Name: Lorazepam
Manufacturer: Biologic Psychotropics India Pvt Ltd
Form: Allopathy
Pregnancy Category: D
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 axitan 1 tablet Uses & Benefits

Anxiety disorders, Insomnia (short-term), Preoperative sedation, Status epilepticus (IV), Alcohol withdrawal syndrome

Off-label uses: Chemotherapy-induced nausea and vomiting, Catatonia, Rapid eye movement sleep behavior disorder

📋 Drug Information

Generic Name(s)	Lorazepam
Brand Name	Ativan
Manufacturer	Biologic Psychotropics India Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	RESPIRATORY
Action Class	Benzodiazepines
Route of Administration	Oral, intravenous, intramuscular
Storage	Store at room temperature (20-25°C) away from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentrations occur within 2 hours.

DistributionWidely distributed throughout the body; crosses the blood-brain barrier and placenta.

Protein BindingApproximately 85% bound to plasma proteins.

MetabolismPrimarily metabolized in the liver via glucuronidation to inactive metabolites.

Half-LifeApproximately 12-18 hours.

ExcretionExcreted mainly in urine as glucuronide conjugates; less than 1% excreted unchanged.

BioavailabilityOral bioavailability is about 90%.

Onset of Action30-60 minutes after oral administration.

Peak Plasma Time2 hours.

Duration of Action6-8 hours.

How It Works

Enhances the inhibitory effect of GABA by binding to benzodiazepine receptors on GABA-A receptors, increasing chloride ion influx and hyperpolarizing neurons.

Mechanism Steps

1Binds to benzodiazepine site on GABA-A receptor

2Increases affinity of GABA for its binding site

3Enhances chloride ion channel opening frequency

💡 How to Take axitan 1 tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of axitan 1 tablet

✅ Common Side Effects

Drowsiness
Dizziness
Ataxia
Weakness
Blurred vision
Sedation

🚨 Serious Side Effects

Respiratory depression
Paradoxical reactions (e.g., agitation, aggression)
Physical dependence and withdrawal
Seizures (with abrupt discontinuation)
Anterograde amnesia

⚠️ Rare Side Effects

Blood dyscrasias (e.g., agranulocytosis)
Jaundice
Allergic reactions
Hypotension
Urinary retention

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Alcohol	Major	Increased CNS depression
Opioids	Major	Severe sedation, respiratory depression
Cimetidine	Moderate	Increased lorazepam levels

🚨 Major Interactions

Opioid analgesics
Other CNS depressants (e.g., barbiturates, alcohol)
Sodium oxybate

⚡ Moderate Interactions

Antipsychotics
Antidepressants (e.g., SSRIs, MAOIs)
Antiepileptics (e.g., valproate)
Antihistamines

ℹ️ Minor Interactions

Caffeine
Oral contraceptives
Smoking (may decrease efficacy)

🍽️ Food Interactions

Grapefruit juice may increase absorption; high-fat meals may delay absorption.

🍷 Alcohol Interaction

Avoid alcohol; additive CNS depression and increased risk of sedation, respiratory depression, and impaired psychomotor function.

🛡️ Safety & Warnings

Liver

Moderate

Kidney

Low

Heart

Low

Pregnancy

Category D

🚫 Contraindications

Hypersensitivity to lorazepam or any benzodiazepine, Acute narrow-angle glaucoma, Severe respiratory insufficiency, Myasthenia gravis, Sleep apnea syndrome, Severe hepatic impairment

📊 Monitoring Parameters

Respiratory rate, Blood pressure, Heart rate, Level of sedation, Liver function tests (if prolonged use), Renal function (if impaired)

🤱 Lactation Safety

Lorazepam is excreted in breast milk; use with caution and monitor infant for sedation and feeding d

💊 Overdose Management

Supportive care; consider flumazenil (benzodiazepine antagonist) but monitor for seizures and arrhythmias.

⏰ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for axitan 1 tablet

View All

Alternative brands with exact same active ingredient (Lorazepam (1mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.