Anxionil 1mg Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Slow, shallow breathing or difficulty breathing
- Severe drowsiness or difficulty waking up
- Confusion, hallucinations, or unusual behavior
- Seizures or convulsions
- Severe allergic reaction with swelling of face, lips, or throat
- Yellowing of skin or eyes (jaundice)
- Unusual bruising or bleeding
- Severe dizziness or fainting
If experiencing severe symptoms, call emergency services immediately.
What is lzepam 1mg tablet used for?
This medicine is a prescription benzodiazepine used for short-term relief of anxiety and for sedation before surgery. It works by enhancing the calming effect of GABA in the brain. It can cause drowsiness and dependence, so it should only be used under medical supervision for the shortest duration possible.
- Generic Name: Lorazepam (1mg)
- Manufacturer: Baroda Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 lzepam 1mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा लोराज़ेपम 1mg टैबलेट है, जिसका उपयोग चिंता (एंग्जायटी) के अल्पकालिक इलाज के लिए किया जाता है। यह मस्तिष्क में गाबा नामक रसायन के प्रभाव को बढ़ाकर मन को शांत करती है। इसका उपयोग सर्जरी से पहले घबराहट कम करने के लिए भी किया जाता है। यह दवा केवल डॉक्टर के पर्चे पर ही मिलती है और इसे 4 सप्ताह से अधिक समय तक नहीं लेना चाहिए क्योंकि इसकी लत लग सकती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, कमजोरी, और थकान शामिल हैं। कुछ लोगों को भ्रम, याददाश्त में कमी, या ध्यान केंद्रित करने में कठिनाई हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, सांस लेने में कठिनाई, या व्यवहार में अचानक बदलाव हो सकते हैं। यदि कोई भी दुष्प्रभाव लंबे समय तक बना रहे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा एक नियंत्रित दवा है और इसे केवल डॉक्टर के निर्देशानुसार ही लें। दवा लेने के बाद गाड़ी चलाने या मशीनरी चलाने से बचें क्योंकि इससे नींद और चक्कर आ सकते हैं। इस दवा के साथ शराब का सेवन बिल्कुल न करें, यह खतरनाक हो सकता है। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। दवा को अचानक बंद न करें, इससे गंभीर लक्षण हो सकते हैं। दवा को बच्चों और पालतू जानवरों से दूर सुरक्षित स्थान पर रखें।
💊 lzepam 1mg tablet Uses & Benefits
[{"condition":"Generalized Anxiety Disorder","description":"Short-term relief of excessive anxiety and worry that interferes with daily functioning.","evidence":"Well-established"},{"condition":"Anxiety associated with depression","description":"Used as an adjunct to antidepressants for rapid control of anxiety symptoms.","evidence":"Well-established"},{"condition":"Pre-operative sedation","description":"Given before surgery or diagnostic procedures to reduce anxiety and promote relaxation.","evidence":"Well-established"},{"condition":"Insomnia due to anxiety","description":"Short-term management of difficulty sleeping caused by anxiety.","evidence":"Moderate"},{"condition":"Panic disorder","description":"May be used short-term to control panic attacks while other treatments take effect.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Chemotherapy-induced nausea and vomiting","description":"Sometimes used as an add-on to standard antiemetics.","evidence":"Limited"},{"condition":"Catatonia","description":"May be used in some cases as an adjunctive treatment.","evidence":"Limited"},{"condition":"Restless legs syndrome","description":"Occasionally prescribed when other treatments fail.","evidence":"Limited"}]
Primary treatment for: Anxiety disorders
Also treats: Insomnia, Panic disorder, Pre-operative anxiety
📋 Drug Information
| Generic Name(s) | Lorazepam (1mg) |
| Brand Name | lzepam 1mg tablet |
| Manufacturer | Baroda Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Benzodiazepines |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to specific sites on the GABA-A receptor complex in the brain. GABA is the primary inhibitory neurotransmitter that reduces nerve excitability. By enhancing GABA's effect, this medicine increases the frequency of chloride channel opening, leading to hyperpolarization of neurons and decreased neuronal firing. This results in anxiolytic, sedative, muscle relaxant, and anticonvulsant effects.
Mechanism Steps
💡 How to Take lzepam 1mg tablet
Strength: This medicine is available as an immediate-release oral tablet containing 1 mg of lorazepam.
Dosage Information
| Adult Dosage | The usual adult dose for anxiety is 1 mg to 3 mg per day, given in divided doses, with the largest dose at bedtime. For pre-operative sedation, a single dose of 2 mg to 4 mg is often given the night before or 1 to 2 hours before the procedure. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to treatment. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the sedative effects of this medicine. The starting dose should be reduced, typically 0.5 mg to 1 mg per day, and increased cautiously if needed. Regular monitoring for falls and cognitive impairment is advised. |
| Renal Impairment | No specific dose adjustment is established for renal impairment. However, use with caution and monitor for increased side effects as metabolites are excreted renally. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, a reduced dose is recommended. This medicine is contraindicated in severe hepatic impairment. |
| Maximum Daily Dose | The maximum recommended daily dose is 10 mg per day, but doses above 4 mg per day are rarely needed and should only be used under close medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of lzepam 1mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Opioids | Major | |
| Alcohol | Major | |
| Clozapine | Major | |
| Oral contraceptives | Moderate | |
| Valproic acid | Moderate | |
| Probenecid | Moderate | |
| Antacids | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- Opioids (e.g., morphine, codeine)
- Alcohol
- CNS depressants (e.g., barbiturates, antipsychotics, sedatives)
- Clozapine
⚡ Moderate Interactions
- Oral contraceptives
- Valproic acid
- Probenecid
🍷 Alcohol Interaction
Alcohol significantly increases the sedative and respiratory depressant effects of this medicine. Combining them can lead to severe drowsiness, impaired coordination, memory loss, and life-threatening breathing difficulties. Avoid alcohol completely while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to lorazepam or other benzodiazepines","Severe hepatic impairment","Narrow-angle glaucoma","Myasthenia gravis","Severe respiratory insufficiency","Sleep apnea syndrome","History of substance misuse or dependence"]
⚠️ Warnings & Precautions
["This medicine can cause physical and psychological dependence even at therapeutic doses. Use for the shortest duration possible.","Abrupt discontinuation after prolonged use can precipitate withdrawal symptoms including seizures. Taper gradually under medical supervision.","This medicine may impair mental and physical abilities required for driving or operating machinery. Avoid these activities until you know how it affects you.","Concomitant use with opioids may cause profound sedation, respiratory depression, coma, and death. Reserve concomitant use for patients with no alternative and monitor closely.","Use with caution in the elderly due to increased sensitivity to sedative effects and risk of falls.","This medicine may cause anterograde amnesia; patients should be advised to ensure they can get uninterrupted sleep for 7-8 hours after taking it.","Do not use in patients with severe liver disease or those with a history of drug or alcohol abuse."]
🤱 Lactation Safety
This medicine is excreted in breast milk and may cause sedation and feeding difficulties in the infant. Breastfeeding is not recommended while taking this medicine. Consult your doctor for alternative options.
💊 Overdose Management
Overdose of this medicine can cause severe drowsiness, confusion, lethargy, respiratory depression, hypotension, and coma. If overdose is suspected, seek emergency medical attention immediately. Treatment is supportive and may include gastric lavage if taken recently, administration of activated charcoal, and monitoring of vital signs. The specific antidote flumazenil may be used with caution in a hospital setting, but it can precipitate seizures in dependent patients.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
This medicine is a controlled prescription medicine and must only be taken exactly as prescribed by your doctor. Do not increase or decrease the dose without medical advice. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness and slow your reactions. Do not drink alcohol while taking this medicine, as it can dangerously increase sedation and respiratory depression. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding, as this medicine may not be suitable for you. Do not stop this medicine suddenly after prolonged use, as it can cause withdrawal symptoms such as anxiety, insomnia, tremors, and seizures. Keep this medicine in a secure place away from children and pets, as it can be harmful if taken accidentally. Regular follow-up with your doctor is essential to monitor your response and to decide when to reduce or stop the medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and cognitive effects of this medicine. They are at higher risk of falls, confusion, and respiratory depression. The starting dose should be lower, and regular monitoring is essential. Long-term use should be avoided if possible.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Benzodiazepines may increase the risk of congenital malformations, especially if taken during the first trimester. Your doctor may recommend alternative treatments or a gradual taper before conception.
🏥 Post-Surgery Considerations
After surgery, this medicine may be used for sedation or anxiety. However, it can increase the risk of respiratory depression, especially when combined with opioid pain relievers. Close monitoring is required. Inform your surgical team if you are taking this medicine regularly.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it can interact with sedatives or anesthetics used during dental procedures. You may need dose adjustments or monitoring. Avoid driving yourself to and from dental appointments if you receive sedation.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause drowsiness, dizziness, and unsteadiness, which may affect your coordination. Avoid activities that require mental alertness, such as driving or operating machinery, until you know how the medicine affects you. Light to moderate exercise is generally safe, but avoid high-risk activities like swimming or cycling until you are sure of your response.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness and impair your ability to concentrate, which may affect your work performance, especially if you operate machinery or drive. It is advisable to discuss with your doctor about temporary work adjustments if your job requires high alertness. Avoid making important decisions until you know how the medicine affects you.
🛑 When to Stop This Medicine
You should stop this medicine only under your doctor's supervision. If you have been taking it for more than a few weeks, your doctor will likely recommend a gradual tapering schedule to prevent withdrawal symptoms. Do not stop abruptly. If you experience side effects that concern you, contact your doctor before making any changes.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to tolerance, meaning you may need higher doses to achieve the same effect. It can also cause physical and psychological dependence. Withdrawal symptoms can occur upon discontinuation, including rebound anxiety, insomnia, irritability, tremors, and in severe cases, seizures. Cognitive effects such as memory problems and difficulty concentrating may also occur. Regular monitoring by a doctor is essential, and the medicine should be tapered gradually when stopping.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A type of talk therapy that helps change negative thought patterns and behaviors contributing to anxiety.
Evidence: Well-establishedAntidepressants that are often used as first-line treatment for anxiety disorders.
Evidence: Well-establishedPractices that can help reduce anxiety and improve emotional well-being.
Evidence: ModeratePhysical activity can reduce anxiety and improve mood.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider that you are taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Since it is a controlled substance, check the laws of your destination country regarding benzodiazepines. Carry enough for your trip and keep it in your hand luggage. Store it at room temperature and protect it from extreme heat or cold. If crossing time zones, consult your doctor about adjusting the dosing schedule to avoid withdrawal symptoms.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking a dose. Peak effects occur around 2 hours.
A: This medicine is intended for short-term use, generally not exceeding 4 weeks, because of the risk of tolerance and dependence.
A: Yes, this medicine can cause physical and psychological dependence, especially with prolonged use. It should only be used under medical supervision.
A: No, stopping suddenly can cause withdrawal symptoms including anxiety, insomnia, tremors, and seizures. Always taper gradually under medical supervision.
A: No, alcohol can dangerously increase the sedative and respiratory depressant effects of this medicine. Avoid alcohol completely.
🤔 Common Patient Concerns
🔄 Substitutes for lzepam 1mg tablet
View AllAlternative brands with exact same active ingredient:
-
biokalm 1mg tabletParadigm Healthcare ₹7.41 2.9% COSTLIER
-
calmese 1mg tabletThemis Medicare Ltd ₹8.20 13.9% COSTLIER
-
anxionil 1mg tabletKonark Biochem ₹9.38 30.3% COSTLIER
-
loralite 1mg tabletElite Pharma Pvt Ltd ₹9.38 30.3% COSTLIER
-
larosh 1mg tabletOsho Pharma Pvt Ltd ₹9.38 30.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe for long-term use.
Fact: This medicine is intended for short-term use only. Prolonged use can lead to tolerance, dependence, and withdrawal symptoms. - Myth: It is okay to stop this medicine suddenly.
Fact: Abrupt discontinuation can cause severe withdrawal symptoms, including seizures. Always taper gradually under medical supervision. - Myth: This medicine can be taken with alcohol to enhance relaxation.
Fact: Combining this medicine with alcohol is dangerous and can cause severe respiratory depression, coma, and death. - Myth: This medicine is safe to take during pregnancy.
Fact: This medicine may harm the fetus. Consult your doctor if you are pregnant or planning pregnancy.
🔄 Alternative Options
Generic Alternatives
- Lorazepam 1 mg tablet
Brand Alternatives
- Ativan
- Lorazepam