amul 50mg tablet - Amisulpride (50mg) medicine

amul 50mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Biologic Psychotropics India Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is amul 50mg tablet used for?

Amisant 200 Tablet (Amisulpride) is used to treat NEURO CNS. It contains Amisulpride (50mg), which Selective antagonist at dopamine D2 and D3 receptors, with higher affinity for D. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Amisulpride
  • Manufacturer: Biologic Psychotropics India Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š amul 50mg tablet Uses & Benefits

Schizophrenia (positive and negative symptoms); acute psychotic episodes; maintenance therapy.

Off-label uses: Bipolar depression, anxiety disorders, obsessive-compulsive disorder (limited evidence).

๐Ÿ“‹ Drug Information

Generic Name(s)Amisulpride
Brand NameAmisant 200 Tablet
ManufacturerBiologic Psychotropics India Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassAtypical Antipsychotics
Route of AdministrationOral
StorageStore at room temperature (15-30ยฐC), protected from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration, with peak plasma concentrations reached within 1-4 hours. Bioavailability is approximately 48% due to first-pass metabolism.
DistributionWidely distributed throughout the body; crosses the blood-brain barrier. Volume of distribution is about 5.8 L/kg.
Protein BindingApproximately 16% bound to plasma proteins.
MetabolismMetabolized in the liver, primarily via CYP3A4, to inactive metabolites. Minor metabolism via other pathways.
Half-LifeApproximately 12 hours (range 10-14 hours).
ExcretionPrimarily excreted in urine (about 70% as unchanged drug and metabolites) and feces (about 20%).
Bioavailability48%
Onset of ActionTherapeutic effects may be observed within a few days to weeks, but full antipsychotic effect may ta
Peak Plasma Time1-4 hours
Duration of ActionApproximately 24 hours due to once-daily dosing.

How It Works

Selective antagonist at dopamine D2 and D3 receptors, with higher affinity for D3 receptors. It also has some antagonistic activity at serotonin 5-HT2A receptors.

Mechanism Steps

1Amisulpride selectively binds to dopamine D2 and D3 receptors, with higher affinity for D3.
2Blocks dopamine receptors in the mesolimbic system, reducing positive symptoms of schizophrenia.
3At low doses, preferentially blocks presynaptic D2/D3 autoreceptors, increasing dopamine release in prefrontal cortex, improving negative symptoms.

๐Ÿ’ก How to Take amul 50mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of amul 50mg tablet

โœ… Common Side Effects

  • Insomnia
  • Anxiety
  • Agitation
  • Weight gain
  • Constipation
  • Nausea
  • Dry mouth
  • Sedation

๐Ÿšจ Serious Side Effects

  • QT prolongation
  • Torsades de pointes
  • Neuroleptic malignant syndrome
  • Seizures
  • Tardive dyskinesia
  • Prolactin elevation (galactorrhea, gynecomastia)

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Agranulocytosis
  • Venous thromboembolism
  • Pancreatitis
  • Allergic reactions

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Levodopa Major Antagonism of dopaminergic effects; reduced efficacy of levodopa.
QT-prolonging drugs Major Increased risk of ventricular arrhythmias.
CYP3A4 inhibitors Major Increased amisulpride plasma concentration; risk of toxicity.
Antihypertensives Moderate Additive hypotensive effect.
CNS depressants Moderate Enhanced sedation and respiratory depression.
Lithium Moderate Increased risk of neurotoxicity.
Antacids Minor Possible reduced absorption of amisulpride.
Cimetidine Minor Slight increase in amisulpride levels.

๐Ÿšจ Major Interactions

  • Levodopa
  • Dopamine agonists
  • QT-prolonging drugs
  • CYP3A4 inhibitors

โšก Moderate Interactions

  • Antihypertensives
  • CNS depressants
  • Lithium

โ„น๏ธ Minor Interactions

  • Antacids
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption but does not significantly affect bioavailability.

๐Ÿท Alcohol Interaction

Alcohol may enhance CNS depressant effects; avoid concurrent use.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to amisulpride; concomitant use with prolactin-dependent tumors; known QT prolongation; severe renal impairment (CrCl <10 mL/min); pheochromocytoma.

๐Ÿ“Š Monitoring Parameters

ECG (QT interval), blood pressure, liver function tests, renal function, prolactin levels, extrapyramidal symptoms.

๐Ÿคฑ Lactation Safety

Not recommended; amisulpride is excreted in breast milk and may cause adverse effects in the infant.

๐Ÿ’Š Overdose Management

Supportive care; ECG monitoring; activated charcoal if recent ingestion; no specific antidote; treat arrhythmias as needed.

โฐ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for amul 50mg tablet

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Alternative brands with exact same active ingredient (Amisulpride (50mg)):

Medical Note: Always consult your doctor before switching medications.

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