awnaron 4mg tablet - Ondansetron (4mg) medicine

Awnaron 4mg Tablet - Uses, Price, Side Effects

4.6 (11 reviews)

Ondansetron (4mg)

🏭 Shawn & Co 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is awnaron 4mg tablet used for?

Awnaron 4mg Tablet contains Ondansetron, a serotonin 5-HT3 receptor antagonist. It is used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery. It works by blocking serotonin, a natural substance that can cause vomiting. Take it as prescribed by your doctor.

Generic Name: Ondansetron
Manufacturer: Shawn & Co
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 awnaron 4mg tablet Uses & Benefits

Prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy; prevention of postoperative nausea and vomiting; prevention of radiotherapy-induced nausea and vomiting.

Off-label uses: Treatment of hyperemesis gravidarum; management of pruritus in cholestasis; treatment of serotonin syndrome (limited evidence).

📋 Drug Information

Generic Name(s)	Ondansetron
Brand Name	Anset 4mg Tablet MD
Manufacturer	Shawn & Co
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	GASTRO INTESTINAL
Action Class	Serotonin antagonists (5-HT3 antagonists)
Route of Administration	Oral (tablet, orally disintegrating tablet, oral solution); intravenous; intramuscular.
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; oral bioavailability is about 60% due to first-pass metabolism.

DistributionWidely distributed in body tissues; volume of distribution approximately 1.8-2.4 L/kg.

Protein Binding70-76% bound to plasma proteins.

MetabolismExtensively metabolized in the liver via CYP1A2, CYP2D6, and CYP3A4; major metabolites are glucuronide conjugates.

Half-LifeApproximately 3-6 hours in adults; longer in elderly (5-7 hours) and hepatic impairment (up to 20 ho

ExcretionPrimarily renal (about 5% unchanged) and fecal; metabolites excreted in urine and bile.

BioavailabilityAbout 60% (oral); 100% (intravenous).

Onset of ActionOral: 30-60 minutes; IV: within minutes.

Peak Plasma TimeOral: 1-2 hours; IV: at end of infusion.

Duration of Action4-8 hours (oral); 4-6 hours (IV).

How It Works

Selective antagonist of serotonin 5-HT3 receptors, blocking serotonin binding in the chemoreceptor trigger zone (CTZ) and gastrointestinal tract, thereby preventing nausea and vomiting.

Mechanism Steps

1Ondansetron binds to 5-HT3 receptors in the chemoreceptor trigger zone (CTZ) of the area postrema and in the gastrointestinal tract.

2Blocks serotonin (5-HT) from binding to these receptors.

3Inhibits the activation of the vomiting reflex pathway.

💡 How to Take awnaron 4mg tablet

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of awnaron 4mg tablet

✅ Common Side Effects

Headache
Constipation
Fatigue
Dizziness
Diarrhea

🚨 Serious Side Effects

QT prolongation
Torsades de pointes
Serotonin syndrome
Hypersensitivity reactions (including anaphylaxis)
Bronchospasm

⚠️ Rare Side Effects

Transient liver enzyme elevation
Blurred vision
Extrapyramidal reactions (dystonia, oculogyric crisis)
Hypokalemia
Hypomagnesemia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Apomorphine	Major	Severe hypotension and loss of consciousness
Tramadol	Moderate	Increased risk of serotonin syndrome
SSRIs	Moderate	Increased risk of serotonin syndrome

🚨 Major Interactions

Apomorphine
Tramadol
Serotonergic drugs (e.g., SSRIs, SNRIs, MAOIs)

⚡ Moderate Interactions

QTc-prolonging agents (e.g., class IA/III antiarrhythmics, certain antipsychotics)
CYP2D6 substrates (e.g., codeine, metoprolol)
CYP3A4 inducers (e.g., rifampin, carbamazepine)
CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)

ℹ️ Minor Interactions

Antacids
Cimetidine

🍽️ Food Interactions

No significant food interactions; may be taken with or without food.

🍷 Alcohol Interaction

Alcohol may increase sedative effects; avoid concurrent use.

🛡️ Safety & Warnings

Liver

Low

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to ondansetron or any component; concomitant use with apomorphine; congenital long QT syndrome.

📊 Monitoring Parameters

ECG (QT interval) in patients at risk; liver function tests if symptoms of hepatotoxicity; electrolyte levels (potassium, magnesium) before IV administration.

🤱 Lactation Safety

Excreted in breast milk in small amounts; caution advised; consider risk-benefit.

💊 Overdose Management

Supportive care; monitor ECG for QT prolongation; no specific antidote; hemodialysis not effective.

⏰ Missed Dose

If a dose is missed, take it as soon as remembered unless it is almost time for the next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for awnaron 4mg tablet

View All

Alternative brands with exact same active ingredient (Ondansetron (4mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026