aenafen 75mg injection - Diclofenac (25mg/ml) medicine

Aenafen 75mg Injection - Uses, Price, Side Effects

4.5 (18 reviews)

Diclofenac (25mg/ml)

🏭 Shawn & Co 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is aenafen 75mg injection used for?

Aenafen 75mg Injection contains Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is used to treat moderate to severe pain, including arthritis, muscle aches, dental pain, and postoperative discomfort. The injection provides rapid relief and is typically administered by a healthcare professional.

Generic Name: Diclofenac
Manufacturer: Shawn & Co
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 aenafen 75mg injection Uses & Benefits

Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, acute gout, dysmenorrhea, musculoskeletal pain, postoperative pain, fever.

Off-label uses: Migraine, renal colic, pericarditis, patent ductus arteriosus closure in neonates.

📋 Drug Information

Generic Name(s)	Diclofenac
Brand Name	Adiflam 50mg Tablet
Manufacturer	Shawn & Co
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	PAIN ANALGESICS
Action Class	NSAID's- Non-Selective COX 1&2 Inhibitors (acetic acid)
Route of Administration	Oral
Storage	Store at room temperature (20-25°C), protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed from the gastrointestinal tract.

DistributionWidely distributed throughout the body; crosses the placenta and enters breast milk.

Protein BindingMore than 99% bound to plasma proteins, primarily albumin.

MetabolismPrimarily hepatic via CYP2C9 and CYP3A4; undergoes first-pass metabolism.

Half-LifeApproximately 2 hours

ExcretionApproximately 65% renal and 35% biliary as metabolites.

BioavailabilityAbout 50% due to first-pass metabolism.

Onset of Action30 minutes to 1 hour

Peak Plasma Time1 to 2 hours

Duration of Action4 to 6 hours

How It Works

Inhibits cyclooxygenase (COX-1 and COX-2) enzymes, reducing prostaglandin synthesis.

Mechanism Steps

1Diclofenac inhibits cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2.

2COX-1 is constitutively expressed and produces prostaglandins involved in gastric protection, platelet aggregation, and renal function.

3COX-2 is induced by inflammation and produces prostaglandins that mediate pain, fever, and inflammation.

💡 How to Take aenafen 75mg injection

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of aenafen 75mg injection

✅ Common Side Effects

Nausea
Vomiting
Diarrhea
Constipation
Dyspepsia
Abdominal pain
Flatulence
Headache
Dizziness
Rash

🚨 Serious Side Effects

GI bleeding
Peptic ulcer
Perforation
Renal failure
Hepatic failure
Myocardial infarction
Stroke
Anaphylaxis
Stevens-Johnson syndrome

⚠️ Rare Side Effects

Pancreatitis
Aseptic meningitis
Hematologic disorders (agranulocytosis, aplastic anemia)
Hepatitis
Nephrotic syndrome
Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Aspirin	Moderate	Increased risk of gastrointestinal bleeding
Lithium	Moderate	Increased lithium levels and toxicity
Methotrexate	Major	Increased methotrexate toxicity
ACE Inhibitors	Minor	Reduced antihypertensive effect

🚨 Major Interactions

Warfarin
Lithium
Methotrexate
Aspirin
Other NSAIDs
Anticoagulants
Corticosteroids

⚡ Moderate Interactions

ACE inhibitors
Diuretics
Cyclosporine
Tacrolimus
Quinolone antibiotics

ℹ️ Minor Interactions

Antacids
Cholestyramine
Digoxin
Phenytoin

🍽️ Food Interactions

Food may delay absorption but does not significantly affect overall bioavailability.

🍷 Alcohol Interaction

Increased risk of gastrointestinal bleeding and ulcers.

🛡️ Safety & Warnings

Liver

Moderate

Kidney

Moderate

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to diclofenac or any NSAID; history of asthma, urticaria, or allergic-type reactions after aspirin/NSAIDs; active peptic ulcer or GI bleeding; severe heart failure; severe renal or hepatic impairment; perioperative pain in CABG surgery.

📊 Monitoring Parameters

Renal function, liver function, blood pressure, signs of GI bleeding, CBC.

🤱 Lactation Safety

Excreted in breast milk; use with caution.

💊 Overdose Management

Symptomatic and supportive; no specific antidote; consider activated charcoal if recent ingestion.

⏰ Missed Dose

Take as soon as remembered unless almost time for next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

🔗 View Profile

🔄 Substitutes for aenafen 75mg injection

View All

Alternative brands with exact same active ingredient (Diclofenac (25mg/ml)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Regular Customer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Verified User Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.