Avospas 20mg/100mg Tablet: Complete Information
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is avospas 20mg/100mg tablet used for?
This medicine is a combination of dicyclomine (an antispasmodic) and nimesulide (an NSAID) used for short-term relief of pain and cramps associated with smooth muscle spasm, such as in irritable bowel syndrome, biliary colic, and dysmenorrhea. It works by relaxing gastrointestinal smooth muscles and reducing inflammation. It should be taken with food and only as prescribed.
- Generic Name: Dicyclomine + Nimesulide
- Manufacturer: Shreeyam Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 avospas 20mg/100mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डाइसाइक्लोमिन और नाइमेसुलाइड का संयोजन है, जिसका उपयोग पेट की ऐंठन, दर्द और सूजन को कम करने के लिए किया जाता है। यह चिड़चिड़ा आंत्र सिंड्रोम (IBS), पित्ताशय की ऐंठन, गुर्दे की पथरी के दर्द और मासिक धर्म के दर्द में राहत देने के लिए दी जाती है। यह दवा केवल डॉक्टर के पर्चे पर ही लेनी चाहिए और खाने के साथ लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मुँह सूखना, चक्कर आना, नींद आना, जी मिचलाना, पेट में असहजता और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन पेट में रक्तस्राव, यकृत की समस्या, गुर्दे की समस्या, या गंभीर एलर्जी हो सकती है। यदि आपको काला मल, खून की उल्टी, पेट में तेज दर्द, आँखों या त्वचा का पीलापन, या पेशाब कम आना जैसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खाने के साथ लें ताकि पेट में जलन न हो। इस दवा के साथ शराब न लें क्योंकि इससे पेट में रक्तस्राव और यकृत की समस्या का खतरा बढ़ सकता है। यदि आपको चक्कर या नींद आती है तो वाहन न चलाएँ। 7 दिनों से अधिक इस दवा का उपयोग बिना डॉक्टर की सलाह के न करें।
💊 avospas 20mg/100mg tablet Uses & Benefits
[{"condition":"Irritable bowel syndrome (IBS)","description":"Helps relieve abdominal cramps and pain associated with IBS by relaxing smooth muscles and reducing inflammation.","evidence":"Moderate"},{"condition":"Biliary colic","description":"Provides relief from pain caused by gallstones or biliary spasm.","evidence":"Limited"},{"condition":"Renal colic","description":"Used for short-term relief of pain from kidney stones, though other treatments are preferred.","evidence":"Limited"},{"condition":"Dysmenorrhea","description":"Relieves menstrual cramps and associated pain.","evidence":"Moderate"},{"condition":"Musculoskeletal pain with spasm","description":"May be used for pain relief in conditions where muscle spasm contributes to discomfort.","evidence":"Limited"}]
Off-label uses: [{"condition":"Gastroenteritis with cramping","description":"Sometimes prescribed to relieve abdominal cramps in infectious gastroenteritis, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Irritable bowel syndrome
Also treats: Biliary colic, Renal colic, Dysmenorrhea, Musculoskeletal pain with spasm
📋 Drug Information
| Generic Name(s) | Dicyclomine + Nimesulide |
| Brand Name | Avospas 20mg/100mg Tablet |
| Manufacturer | Shreeyam Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antispasmodic + NSAID |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Dicyclomine is a antimuscarinic agent that blocks acetylcholine at muscarinic receptors on smooth muscle, reducing spasms in the gastrointestinal tract. Nimesulide is a non-steroidal anti-inflammatory drug that selectively inhibits cyclooxygenase-2 (COX-2), decreasing the production of prostaglandins, which are mediators of pain and inflammation. Together, they provide both antispasmodic and anti-inflammatory effects.
Mechanism Steps
💡 How to Take avospas 20mg/100mg tablet
Strength: Tablet containing Dicyclomine 20 mg and Nimesulide 100 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally two to three times daily, preferably with food. The exact dose and duration must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. Do not use for more than 7 days without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine. Use with caution and lower doses may be appropriate. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with kidney impairment. Dose adjustment may be necessary. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with liver impairment. Dose adjustment may be necessary. Avoid in severe liver disease. Consult a doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 3 tablets (Dicyclomine 60 mg + Nimesulide 300 mg). Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of avospas 20mg/100mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Anticholinergics | Major | |
| ACE inhibitors/ARBs | Moderate | |
| Diuretics | Moderate | |
| Lithium | Moderate | |
| Methotrexate | Moderate | |
| Antacids | Minor | |
| Alcohol | Major |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, aspirin)
- Corticosteroids
- Anticholinergic drugs (e.g., atropine, antihistamines)
⚡ Moderate Interactions
- ACE inhibitors and ARBs
- Diuretics
- Lithium
- Methotrexate
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver toxicity associated with nimesulide. It may also enhance the sedative and anticholinergic effects of dicyclomine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to dicyclomine, nimesulide, or any component of the formulation.","Active peptic ulcer disease or history of recurrent ulcers.","Severe liver impairment or active liver disease.","Severe kidney impairment (e.g., creatinine clearance
⚠️ Warnings & Precautions
["Use with caution in elderly patients due to increased risk of side effects.","Avoid in patients with cardiovascular disease or risk factors.","May cause drowsiness or dizziness; avoid driving or operating machinery.","Do not use for prolonged periods without medical supervision.","May mask signs of infection.","Use with caution in patients with glaucoma or urinary retention.","Avoid alcohol consumption.","Not recommended for children."]
🤱 Lactation Safety
Not established from the available information. Dicyclomine and nimesulide may pass into breast milk. Consult your doctor before use.
💊 Overdose Management
Overdose may cause severe anticholinergic effects (dry mouth, blurred vision, urinary retention, tachycardia, confusion) and NSAID toxicity (nausea, vomiting, gastrointestinal bleeding, kidney failure). Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take it with food or milk to reduce stomach upset. Avoid alcohol while taking this medicine as it can increase the risk of gastrointestinal bleeding and liver problems. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, asthma, or bleeding disorders. Do not use this medicine for more than 7 days without medical advice. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to side effects such as dizziness, dry mouth, and gastrointestinal bleeding. Use with caution and lower doses may be appropriate.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. Consult your doctor for alternative treatments.
🏥 Post-Surgery Considerations
Use with caution after surgery due to increased risk of bleeding and kidney problems. Consult your surgeon before taking this medicine.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may increase bleeding risk during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel dizzy or drowsy. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as gastrointestinal bleeding, liver problems, or allergic reactions. Do not stop abruptly without consulting your doctor if you have been on long-term therapy.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of gastrointestinal bleeding, liver toxicity, kidney impairment, and cardiovascular events. It should only be used short-term unless specifically advised by a doctor. Regular monitoring of liver and kidney function may be required.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedAvoiding trigger foods can help manage IBS symptoms.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. Consult your doctor regarding vaccinations while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 1-2 hours after taking it.
A: It is best taken with food or milk to reduce the risk of stomach upset.
A: Do not take other NSAIDs without consulting your doctor, as it may increase the risk of side effects.
🤔 Common Patient Concerns
🔄 Substitutes for avospas 20mg/100mg tablet
View AllAlternative brands with exact same active ingredient:
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nelsid d 20 mg/100 mg tabletInd Swift Laboratories Ltd ₹4.95 72.2% CHEAPER
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nispal 20mg/100mg tabletAlmed Drugs Pvt Ltd ₹9.38 47.3% CHEAPER
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nidic tabletMeridian Medicare Ltd ₹12.17 31.7% CHEAPER
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spas n 20mg/100mg tabletMediwin Pharmaceuticals ₹12.19 31.6% CHEAPER
-
Nuspas TabletNumed ₹14.06 21.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken for any type of pain.
Fact: This medicine is specifically for pain associated with smooth muscle spasm and inflammation. It is not a general painkiller for all types of pain. - Myth: It is safe to take this medicine for long periods.
Fact: Prolonged use can increase the risk of liver, kidney, and gastrointestinal problems. It should only be used short-term as prescribed. - Myth: This medicine is safe for children.
Fact: This medicine is not recommended for children under 12 years due to lack of established safety and efficacy.
🔄 Alternative Options
Generic Alternatives
- Dicyclomine + Nimesulide combination tablets from other manufacturers.
Brand Alternatives
- Avospas 20mg/100mg Tablet