Arsulide D 20 mg/100 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is nispal 20mg/100mg tablet used for?
This medicine is a combination of dicyclomine (an antispasmodic) and nimesulide (an NSAID) used for short-term relief of acute abdominal cramps and musculoskeletal pain. It works by relaxing smooth muscles and reducing inflammation. It should be taken with food and not for prolonged periods.
- Generic Name: Dicyclomine (20mg) + Nimesulide (100mg)
- Manufacturer: Almed Drugs Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 nispal 20mg/100mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डाइसाइक्लोमिन और नाइमसुलाइड का संयोजन है, जिसका उपयोग पेट की ऐंठन, मरोड़ और दर्द के इलाज के लिए किया जाता है। यह मांसपेशियों को आराम देती है और सूजन को कम करती है। यह अक्सर चिड़चिड़ा आंत्र सिंड्रोम (IBS), पेट दर्द, और मासिक धर्म के दर्द में राहत के लिए दी जाती है। इसे डॉक्टर की सलाह के अनुसार ही लें और खाने के साथ लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मुंह सूखना, चक्कर आना, नींद आना, जी मिचलाना, पेट दर्द, और दस्त शामिल हैं। गंभीर दुष्प्रभावों में पेट में रक्तस्राव, अल्सर, किडनी की समस्या, लीवर की समस्या, और गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको काला मल, खून की उल्टी, तेज पेट दर्द, आंखों या त्वचा का पीलापन, या पेशाब कम आना जैसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को खाने के साथ या दूध के साथ लें ताकि पेट में जलन न हो। शराब न पिएं क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। यदि आपको चक्कर या नींद आती है तो वाहन न चलाएं। गर्भवती या स्तनपान कराने वाली महिलाएं बिना डॉक्टर की सलाह के इस दवा का सेवन न करें। बच्चों को यह दवा न दें। डॉक्टर द्वारा बताई गई अवधि से ज्यादा इसका इस्तेमाल न करें।
💊 nispal 20mg/100mg tablet Uses & Benefits
[{"condition":"Acute abdominal cramps","description":"Relieves painful spasms of the gastrointestinal tract, often associated with irritable bowel syndrome or gastroenteritis.","evidence":"Well-established"},{"condition":"Irritable bowel syndrome (IBS)","description":"Helps reduce abdominal pain and cramping by relaxing smooth muscles and reducing inflammation.","evidence":"Moderate"},{"condition":"Musculoskeletal pain","description":"Provides short-term relief of pain and inflammation in conditions like muscle strains and sprains.","evidence":"Moderate"},{"condition":"Dysmenorrhea","description":"May help relieve menstrual cramps due to antispasmodic and anti-inflammatory effects.","evidence":"Limited"}]
Off-label uses: [{"condition":"Biliary colic","description":"Sometimes used off-label to relieve pain from gallbladder spasms.","evidence":"Limited"},{"condition":"Urinary tract spasms","description":"May be used off-label to reduce bladder spasms.","evidence":"Limited"}]
Primary treatment for: Acute abdominal cramps associated with smooth muscle spasm
Also treats: Irritable bowel syndrome, Musculoskeletal pain, Dysmenorrhea
📋 Drug Information
| Generic Name(s) | Dicyclomine (20mg) + Nimesulide (100mg) |
| Brand Name | nispal 20mg/100mg tablet |
| Manufacturer | Almed Drugs Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients. Dicyclomine blocks muscarinic acetylcholine receptors in the gastrointestinal tract, reducing smooth muscle contractions and spasms. Nimesulide selectively inhibits cyclooxygenase-2 (COX-2) enzyme, decreasing the production of prostaglandins, which are mediators of pain, inflammation, and fever. Together, they provide antispasmodic and anti-inflammatory effects.
Mechanism Steps
💡 How to Take nispal 20mg/100mg tablet
Strength: Tablet containing Dicyclomine 20 mg and Nimesulide 100 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally one to two times daily, or as directed by a physician. The dose may vary based on the condition being treated and the patient's response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially anticholinergic effects and gastrointestinal bleeding. Use with caution and lower doses may be appropriate. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor. Not recommended in severe renal impairment. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Avoid in severe hepatic impairment. |
| Maximum Daily Dose | The maximum recommended daily dose is 2 tablets (Dicyclomine 40 mg + Nimesulide 200 mg). Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of nispal 20mg/100mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Other NSAIDs | Major | |
| Corticosteroids | Major | |
| Anticholinergics | Major | |
| ACE inhibitors/ARBs | Moderate | |
| Diuretics | Moderate | |
| Lithium | Moderate | |
| Methotrexate | Moderate | |
| Antacids | Minor | |
| Alcohol | Major |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, aspirin)
- Corticosteroids
- Anticholinergics (e.g., atropine, antihistamines)
⚡ Moderate Interactions
- ACE inhibitors, ARBs
- Diuretics
- Lithium
- Methotrexate
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulcers, and liver toxicity. It may also worsen dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to dicyclomine, nimesulide, or any component of the formulation","Active peptic ulcer or history of recurrent ulcers","Severe liver impairment","Severe kidney impairment","Inflammatory bowel disease (e.g., ulcerative colitis, Crohn's disease)","Severe heart failure","Children below 12 years of age","Pregnancy (especially third trimester)","Breastfeeding"]
⚠️ Warnings & Precautions
["Take with food to reduce stomach upset.","Avoid alcohol and other NSAIDs.","Do not drive or operate machinery if you experience dizziness or drowsiness.","Use with caution in elderly patients due to increased risk of side effects.","Inform your doctor if you have a history of kidney or liver disease, asthma, or heart problems.","Do not use for longer than prescribed without medical advice.","Stop and consult a doctor if you experience signs of gastrointestinal bleeding, liver problems, or allergic reactions."]
🤱 Lactation Safety
Not established from the available information. Dicyclomine may pass into breast milk and could cause anticholinergic effects in the infant. Nimesulide is not recommended during breastfeeding. Consult your doctor before use.
💊 Overdose Management
Overdose may cause severe abdominal pain, nausea, vomiting, drowsiness, dry mouth, blurred vision, and increased heart rate. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine with food or milk to reduce stomach upset. Do not exceed the recommended dose or duration. Avoid alcohol as it increases the risk of stomach bleeding. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of ulcers, kidney or liver disease, asthma, or heart problems. Do not take other NSAIDs or pain relievers without consulting your doctor. Stay well hydrated. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before taking this medicine. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more susceptible to the side effects of this medicine, especially anticholinergic effects (dry mouth, constipation, urinary retention) and gastrointestinal bleeding. Use with caution and lower doses may be appropriate. Regular monitoring of kidney and liver function is recommended.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. NSAIDs like nimesulide can affect ovulation and may increase the risk of miscarriage. Consult your doctor for alternative treatments if you are planning pregnancy.
🏥 Post-Surgery Considerations
This medicine may increase the risk of bleeding and interfere with wound healing after surgery. Consult your surgeon before taking this medicine post-surgery. Alternative pain management options may be recommended.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase the risk of bleeding. Your dentist may advise you to stop the medicine temporarily before surgery.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, especially if you experience dizziness or drowsiness. Gentle stretching and low-impact activities are generally safe. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to take rest if you experience abdominal cramps or muscle pain. Inform your employer if your work involves operating heavy machinery.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor immediately if you experience any serious side effects such as blood in stool, severe abdominal pain, yellowing of skin or eyes, decreased urine output, or allergic reactions. Do not stop taking this medicine without consulting your doctor if you are on a prescribed course.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended due to the risk of serious side effects such as gastrointestinal bleeding, ulcers, kidney impairment, and liver toxicity. If you need to take it for more than 7 days, your doctor should monitor your liver and kidney function regularly. Always consult your doctor before extending the duration of treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and muscle spasms.
Evidence: Well-establishedApplying heat or cold packs can help relieve muscle spasms and pain.
Evidence: ModerateAvoiding trigger foods can help manage IBS symptoms.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check local customs regulations regarding prescription medicines. Always carry enough supply for your trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain and cramps within 1-2 hours after taking it.
A: It is best to take this medicine with food or milk to reduce the risk of stomach upset and ulcers.
A: Do not take other NSAIDs or painkillers without consulting your doctor, as it may increase the risk of side effects.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
🤔 Common Patient Concerns
🔄 Substitutes for nispal 20mg/100mg tablet
View AllAlternative brands with exact same active ingredient:
-
nelsid d 20 mg/100 mg tabletInd Swift Laboratories Ltd ₹4.95 47.2% CHEAPER
-
nidic tabletMeridian Medicare Ltd ₹12.17 29.7% COSTLIER
-
spas n 20mg/100mg tabletMediwin Pharmaceuticals ₹12.19 30% COSTLIER
-
Nuspas TabletNumed ₹14.06 49.9% COSTLIER
-
menark tabletSysmed Laboratories Pvt Ltd ₹14.60 55.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic pain.
Fact: This medicine is for short-term use only. Long-term use increases the risk of serious side effects like gastrointestinal bleeding and liver toxicity. - Myth: It is safe to take this medicine without food.
Fact: Taking this medicine without food increases the risk of stomach upset and ulcers. Always take it with food or milk. - Myth: This medicine is safe during pregnancy.
Fact: This medicine is not recommended during pregnancy, especially in the third trimester, due to potential harm to the fetus.
🔄 Alternative Options
Generic Alternatives
- Dicyclomine + Nimesulide combination tablets from other manufacturers
Brand Alternatives
- Arsulide D 20 mg/100 mg Tablet