Atromend-AS 20/150 Capsule: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unexplained muscle pain or weakness with dark urine
If experiencing severe symptoms, call emergency services immediately.
What is atorise asp 20mg/150mg capsule used for?
This medicine is a combination of Atorvastatin 20 mg and Aspirin 150 mg used to lower cholesterol and prevent blood clots in patients at risk of cardiovascular events. It is taken orally once daily as prescribed by a doctor.
- Generic Name: Atorvastatin + Aspirin
- Manufacturer: Carise Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 atorise asp 20mg/150mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा एटोरवास्टेटिन 20 मिलीग्राम और एस्पिरिन 150 मिलीग्राम का संयोजन है। इसका उपयोग कोलेस्ट्रॉल कम करने और रक्त के थक्के बनने से रोकने के लिए किया जाता है, जिससे दिल का दौरा और स्ट्रोक का खतरा कम होता है। यह उन रोगियों के लिए निर्धारित की जाती है जिन्हें हृदय रोग या उसके जोखिम कारक हैं। यह दवा केवल डॉक्टर की सलाह पर ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में अपच, पेट में जलन, मतली, आसानी से चोट लगना या खून बहना, मांसपेशियों में दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों में रक्तस्राव, मांसपेशियों का टूटना (रैब्डोमायोलिसिस), और यकृत की समस्या शामिल हैं। यदि आपको काला मल, उल्टी में खून, या गंभीर पेट दर्द हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के निर्देशानुसार ही लें। इसे चबाएं या तोड़ें नहीं, पूरा निगल लें। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव और यकृत की समस्या का खतरा बढ़ता है। बिना डॉक्टर की सलाह के कोई अन्य दर्द निवारक या रक्त पतला करने वाली दवा न लें। नियमित रूप से लीवर और किडनी की जांच कराएं। यदि आपको असामान्य रक्तस्राव, मांसपेशियों में दर्द, या पेशाब का रंग गहरा हो, तो तुरंत डॉक्टर को बताएं।
💊 atorise asp 20mg/150mg capsule Uses & Benefits
[{"condition":"Secondary prevention of cardiovascular events","description":"Used in patients with established coronary artery disease, cerebrovascular disease, or peripheral arterial disease to reduce the risk of heart attack, stroke, and revascularization procedures.","evidence":"Well-established"},{"condition":"Primary prevention in high-risk individuals","description":"May be prescribed for patients with multiple risk factors such as diabetes, hypertension, and dyslipidemia who are at high risk of cardiovascular events.","evidence":"Established"},{"condition":"Hypercholesterolemia","description":"Atorvastatin component lowers LDL cholesterol and triglycerides while modestly increasing HDL cholesterol.","evidence":"Well-established"},{"condition":"Acute coronary syndrome","description":"Aspirin component is used for its antiplatelet effect in the acute setting and for secondary prevention after myocardial infarction.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Prevention of preeclampsia","description":"Low-dose aspirin is sometimes used off-label for prevention of preeclampsia in high-risk pregnant women, but this combination is not standard for this purpose.","evidence":"Limited"},{"condition":"Colorectal cancer prevention","description":"Aspirin has been studied for chemoprevention of colorectal cancer, but this combination is not approved for this indication.","evidence":"Investigational"}]
Primary treatment for: Cardiovascular disease prevention
Also treats: Hypercholesterolemia, Coronary artery disease, Cerebrovascular disease, Peripheral arterial disease, Diabetes mellitus with cardiovascular risk
📋 Drug Information
| Generic Name(s) | Atorvastatin + Aspirin |
| Brand Name | Aztor Asp 75 Capsule |
| Manufacturer | Carise Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | HMG-CoA Reductase Inhibitor + Antiplatelet Agent |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and direct sunlight. Store in the original container to protect from light. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. Guidelines from organizations such as the American College of Cardiology and American Heart Association recommend statins and aspirin for secondary prevention of cardiovascular events in appropriate patients. However, the specific combination product may not be directly addressed. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research has guidelines for cardiovascular disease prevention, but specific recommendations for this combination product are not available. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Atorvastatin selectively and competitively inhibits HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol synthesis, leading to upregulation of LDL receptors and increased clearance of LDL cholesterol from the blood. Aspirin irreversibly acetylates cyclooxygenase-1 (COX-1) in platelets, preventing the conversion of arachidonic acid to prostaglandin H2 and subsequently thromboxane A2, a potent platelet aggregator and vasoconstrictor. This antiplatelet effect lasts for the lifespan of the platelet, typically 7 to 10 days.
Mechanism Steps
💡 How to Take atorise asp 20mg/150mg capsule
Strength: Capsule containing Atorvastatin 20 mg and Aspirin 150 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule taken orally once daily, preferably at the same time each day. The dose may be adjusted by your doctor based on your cholesterol levels, cardiovascular risk, and response to treatment. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and concomitant medications. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of this medicine, particularly the risk of bleeding and muscle side effects. The dose should be individualized by a clinician, and regular monitoring of renal and hepatic function is recommended. |
| Renal Impairment | Use with caution in patients with renal impairment. Aspirin may worsen renal function, and atorvastatin may increase the risk of rhabdomyolysis. Dose adjustment may be necessary based on creatinine clearance. Consult your doctor for individualized dosing. |
| Hepatic Impairment | This medicine is contraindicated in patients with active liver disease or unexplained persistent transaminase elevations. In patients with mild to moderate hepatic impairment, dose reduction may be considered. Regular monitoring of liver function is essential. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is one capsule containing Atorvastatin 20 mg and Aspirin 150 mg. Do not exceed this dose unless directed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of atorise asp 20mg/150mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| NSAIDs | Major | |
| Clopidogrel | Major | |
| Methotrexate | Major | |
| Cyclosporine | Moderate | |
| Gemfibrozil | Moderate | |
| Azole antifungals | Moderate | |
| Macrolide antibiotics | Moderate | |
| Protease inhibitors | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other anticoagulants (e.g., heparin, apixaban, rivaroxaban)
- NSAIDs (e.g., ibuprofen, naproxen)
- Methotrexate
- Clopidogrel
⚡ Moderate Interactions
- Cyclosporine
- Gemfibrozil
- Azole antifungals (e.g., itraconazole, ketoconazole)
- Macrolide antibiotics (e.g., clarithromycin, erythromycin)
- Protease inhibitors (e.g., ritonavir, saquinavir)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding due to aspirin's antiplatelet effect and can exacerbate liver toxicity from atorvastatin. Chronic alcohol use may also increase the risk of muscle-related side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to atorvastatin, aspirin, or any component of the formulation","Active liver disease or unexplained persistent elevations of serum transaminases","Active bleeding or bleeding disorders (e.g., hemophilia, thrombocytopenia)","History of aspirin-sensitive asthma or aspirin-induced angioedema","Severe renal impairment (for aspirin component)","Pregnancy and lactation","Children under 18 years of age (safety and efficacy not established)","Concurrent use with live vaccines"]
⚠️ Warnings & Precautions
["This medicine may increase the risk of bleeding. Avoid activities that may cause injury and report any unusual bleeding.","Do not use this medicine if you have an active infection, as aspirin may mask signs of infection.","Atorvastatin may cause muscle pain, tenderness, or weakness. Report these symptoms promptly.","Avoid alcohol consumption as it increases the risk of liver and stomach problems.","Inform your doctor if you have diabetes, as atorvastatin may increase blood sugar levels.","Use with caution in elderly patients, who are more prone to bleeding and muscle side effects.","Do not take this medicine with other NSAIDs or blood thinners unless prescribed.","This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you."]
🤱 Lactation Safety
Not established from the available information. Atorvastatin and aspirin are excreted in breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue the medicine, taking into account the importance of the medicine to the mother. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause symptoms such as severe gastrointestinal bleeding, tinnitus, hyperventilation, and metabolic acidosis due to aspirin toxicity. Atorvastatin overdose may lead to muscle toxicity. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. Activated charcoal may be administered if ingestion is recent. Hemodialysis is not effective for atorvastatin but may be considered for salicylate toxicity. Monitor vital signs, electrolytes, and acid-base balance.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not crush, chew, or open the capsule; swallow it whole with a glass of water. Take it at the same time each day to maintain consistent blood levels. Avoid alcohol consumption as it increases the risk of stomach bleeding and liver problems. Do not take other pain relievers or blood thinners without consulting your doctor. Inform all healthcare providers, including dentists, that you are taking this medicine. Regular monitoring of liver function, kidney function, and blood counts is essential. If you experience any signs of bleeding, such as nosebleeds, gum bleeding, or blood in urine or stool, seek medical attention immediately. Do not stop this medicine abruptly without medical advice, as it may increase cardiovascular risk.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, renal impairment, and muscle side effects. The dose should be individualized, and regular monitoring of renal and hepatic function is recommended. Falls prevention strategies should be discussed to reduce bleeding risk.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. Atorvastatin may harm the fetus, and aspirin may cause complications. Consult your doctor to discuss alternative treatments and preconception planning.
🏥 Post-Surgery Considerations
This medicine may increase the risk of bleeding after surgery. Inform your surgeon that you are taking this medicine. It may need to be stopped before surgery as advised by your doctor. Do not restart without medical advice.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it increases the risk of bleeding during dental procedures. Your dentist may recommend stopping the medicine temporarily or taking precautions to control bleeding.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged, but avoid activities that may cause injury or bleeding, especially if you are prone to bleeding. If you experience muscle pain, tenderness, or weakness, stop exercising and consult your doctor, as this may be a sign of a rare muscle condition.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or bleeding, which could affect your ability to drive or operate machinery. Avoid driving or operating heavy machinery until you know how this medicine affects you. Inform your employer if your job involves activities that could increase the risk of bleeding or injury.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as severe bleeding, muscle pain, or liver problems, your doctor may advise you to stop. In some cases, this medicine may be stopped before surgery or dental procedures. Always follow your doctor's guidance.
📅 Long-Term Use Effects
Long-term use of this medicine is associated with a reduced risk of cardiovascular events. However, it requires regular monitoring of liver function, renal function, and lipid profile. Prolonged use of aspirin can increase the risk of gastrointestinal bleeding and ulcers. Atorvastatin may increase the risk of new-onset diabetes and muscle-related side effects. Regular follow-up with your doctor is essential to monitor for these effects and adjust treatment as needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight management can help control cholesterol and reduce cardiovascular risk.
Evidence: Well-establishedRosuvastatin or simvastatin may be used as alternatives to atorvastatin.
Evidence: Well-establishedClopidogrel or ticagrelor may be used instead of aspirin in some patients.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with most vaccines. However, live vaccines should be avoided in patients on immunosuppressive doses of aspirin. Consult your doctor before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss or exposure to extreme temperatures. If crossing time zones, continue taking your dose at the same time each day according to your home schedule, or adjust gradually as advised by your doctor. Store at room temperature and avoid leaving it in a hot car. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The antiplatelet effect of aspirin starts within 30 to 60 minutes, while the cholesterol-lowering effect of atorvastatin begins within 2 weeks and reaches maximum effect in 4 to 6 weeks.
A: You should inform your doctor about all medications you are taking, as this medicine can interact with many drugs, including blood thinners, NSAIDs, and certain antibiotics.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine is generally not recommended during pregnancy. Consult your doctor if you are pregnant or planning to become pregnant.
A: No, do not stop taking this medicine without consulting your doctor. It is often continued long-term to maintain cardiovascular protection.
🤔 Common Patient Concerns
🔄 Substitutes for atorise asp 20mg/150mg capsule
View AllAlternative brands with exact same active ingredient:
-
davaindia atorvastatin+aspirin 20mg/150mg capsuleDavaindia Generic Pharmacy ₹23.00 4.5% COSTLIER
-
davaindia aspirin+atorvastatin+clopidogrel 150mg/20mg/75mg capsuleDavaindia Generic Pharmacy ₹42.00 90.9% COSTLIER
-
tonact-asp 20/150 capsuleLupin Ltd ₹43.40 97.3% COSTLIER
-
ecosprin av 150/20 capsuleUSV Ltd ₹73.45 233.9% COSTLIER
-
jovastatin ap 20mg/150mg capsuleJohnlee Pharmaceuticals Pvt Ltd ₹75.94 245.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without a prescription.
Fact: This medicine is a prescription drug and should only be taken under medical supervision. - Myth: It is safe to take this medicine with other pain relievers.
Fact: Taking this medicine with other NSAIDs or blood thinners can increase the risk of bleeding and other side effects. - Myth: This medicine can be stopped once cholesterol levels are normal.
Fact: This medicine is often continued long-term to maintain cardiovascular protection. Do not stop without consulting your doctor.
🔄 Alternative Options
Generic Alternatives
- Atorvastatin 20 mg + Aspirin 150 mg capsule (generic)
Brand Alternatives
- Atromend-AS 20/150 capsule