Atorise ASP 20mg/75mg Capsule - Uses, Price, Side Effects
What is atorise asp 20mg/75mg capsule used for?
Atorise ASP 20mg/75mg Capsule combines Atorvastatin (20mg) and Aspirin (75mg) to lower cholesterol and prevent blood clots, reducing the risk of heart attack and stroke in patients with cardiovascular disease. It is taken once daily, usually in the evening, under medical supervision.
- Generic Name: Atorvastatin + Aspirin
- Manufacturer: Carise Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ atorise asp 20mg/75mg capsule Uses & Benefits
Primary and secondary prevention of cardiovascular events in patients with hyperlipidemia and at risk of thrombotic events.
Off-label uses: Not applicable.
๐ Drug Information
| Generic Name(s) | Atorvastatin + Aspirin |
| Brand Name | Aztor Asp 75 Capsule |
| Manufacturer | Carise Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | HMG-CoA Reductase Inhibitor + Antiplatelet Agent |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Atorvastatin: Inhibits HMG-CoA reductase, reducing cholesterol synthesis; Aspirin: Irreversibly inhibits cyclooxygenase (COX-1), reducing thromboxane A2 production and platelet aggregation.
Mechanism Steps
๐ก How to Take atorise asp 20mg/75mg capsule
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of atorise asp 20mg/75mg capsule
โ Common Side Effects
- Headache
- Dizziness
- Nausea
- Diarrhea
- Muscle pain
- Dyspepsia
- Increased liver enzymes
๐จ Serious Side Effects
- Rhabdomyolysis
- Hepatotoxicity
- Gastrointestinal bleeding
- Hemorrhagic stroke
- Stevens-Johnson syndrome
โ ๏ธ Rare Side Effects
- Myopathy
- Pancreatitis
- Thrombocytopenia
- Interstitial lung disease
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| NSAIDs | Major | Increased risk of gastrointestinal bleeding |
| Clopidogrel | Moderate | Additive antiplatelet effect |
| Methotrexate | Moderate | Increased methotrexate toxicity |
| Antacids | Minor | Reduced absorption of atorvastatin |
๐จ Major Interactions
- Warfarin
- Ciclosporin
- Clarithromycin
- Itraconazole
- HIV protease inhibitors
- Methotrexate
โก Moderate Interactions
- Digoxin
- Oral contraceptives
- Colchicine
- Antacids
- Fibrates
- Niacin
โน๏ธ Minor Interactions
- Grapefruit juice
- Vitamin K antagonists (low dose)
- Spironolactone
๐ฝ๏ธ Food Interactions
Grapefruit juice increases atorvastatin levels; avoid high-fat meals with aspirin.
๐ท Alcohol Interaction
Increased risk of gastrointestinal bleeding with aspirin; alcohol may affect atorvastatin metabolism.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Active liver disease, unexplained persistent liver enzyme elevations, pregnancy, breastfeeding, active peptic ulcer, bleeding disorders, hypersensitivity to any component.
๐ Monitoring Parameters
Liver function tests, lipid profile, renal function, signs of bleeding, INR if on warfarin.
๐คฑ Lactation Safety
Atorvastatin: Not recommended; Aspirin: Excreted in breast milk, avoid high doses.
๐ Overdose Management
Symptomatic and supportive care; for aspirin overdose, consider gastric lavage, activated charcoal, and hemodialysis in severe cases.
โฐ Missed Dose
Take as soon as remembered unless close to next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.
Effective and reliable. Worked as expected.