allexit 2mg tablet - Loperamide (2mg) medicine

Andial 2mg Tablet: Complete Guide to Uses, Dosage, and Safety

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🏭 Carise Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for acute and chronic diarrhea.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • High fever with diarrhea
  • Severe abdominal pain or bloating
  • Signs of dehydration (dry mouth, decreased urine, dizziness)
  • Fast, irregular, or pounding heartbeat
  • Swelling of face, lips, or throat
  • Difficulty breathing or shortness of breath
  • Severe constipation or inability to pass stool

If experiencing severe symptoms, call emergency services immediately.

What is allexit 2mg tablet used for?

This medicine is an antidiarrheal tablet containing loperamide 2 mg. It works by slowing down intestinal movement, allowing more water to be absorbed from the stool. It is used for acute and chronic diarrhea in adults and children over 12 years. Do not exceed the recommended dose.

  • Generic Name: Loperamide
  • Manufacturer: Carise Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 allexit 2mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा लोपरामाइड 2 मिलीग्राम की गोली है, जिसका उपयोग दस्त (डायरिया) के इलाज के लिए किया जाता है। यह आंतों की गति को धीमा करके दस्त को कम करती है और शरीर में पानी की कमी को रोकने में मदद करती है। यह तीव्र दस्त और पुरानी दस्त दोनों में प्रभावी है। इसका उपयोग 12 वर्ष से अधिक उम्र के बच्चों और वयस्कों में किया जा सकता है। ध्यान रखें कि यह दवा खूनी दस्त, तेज बुखार या बैक्टीरियल संक्रमण में नहीं लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में कब्ज, पेट में ऐंठन, जी मिचलाना, मुंह सूखना, चक्कर आना और नींद आना शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें आंतों का रुक जाना, दिल की धड़कन में गड़बड़ी और एलर्जी की प्रतिक्रिया शामिल हो सकती है। अगर आपको गंभीर कब्ज, पेट में तेज दर्द, या दिल की धड़कन तेज या अनियमित महसूस हो, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। ज्यादा मात्रा में न लें क्योंकि इससे दिल की गंभीर समस्याएं हो सकती हैं। दस्त के दौरान ओआरएस (ओरल रिहाइड्रेशन सॉल्यूशन) और पानी पीते रहें ताकि शरीर में पानी की कमी न हो। शराब और नींद लाने वाली दवाओं से बचें। बिना डॉक्टर की सलाह के 2 दिन से ज्यादा इस दवा का इस्तेमाल न करें। अगर दस्त 48 घंटे से ज्यादा रहे, बुखार आए या मल में खून दिखे, तो दवा बंद करें और डॉक्टर से मिलें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 allexit 2mg tablet Uses & Benefits

[{"condition":"Acute nonspecific diarrhea","description":"This medicine reduces stool frequency and urgency by slowing intestinal motility, allowing more fluid absorption.","evidence":"Well-established"},{"condition":"Chronic diarrhea associated with inflammatory bowel disease","description":"It helps control chronic diarrhea in conditions like Crohn's disease and ulcerative colitis when used under medical supervision.","evidence":"Well-established"},{"condition":"Traveler's diarrhea","description":"This medicine provides symptomatic relief of mild traveler's diarrhea but should not be used if there is fever or bloody stools.","evidence":"Well-established"},{"condition":"Diarrhea from chemotherapy or other medications","description":"Sometimes used to manage mild chemotherapy-induced diarrhea, but only after ruling out infection.","evidence":"Limited"}]

Off-label uses: [{"condition":"Short bowel syndrome","description":"May be used off-label to reduce stool output in patients with short bowel syndrome, but only under specialist care.","evidence":"Limited"},{"condition":"High-output ileostomy","description":"Occasionally used to reduce ileostomy output, but this requires careful medical supervision.","evidence":"Limited"}]

Primary treatment for: Diarrhea

Also treats: Inflammatory bowel disease, Irritable bowel syndrome with diarrhea, Traveler's diarrhea

📋 Drug Information

Generic Name(s)Loperamide
Brand NameAndial 2mg Tablet
ManufacturerCarise Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassOpioid Agonist- Antidiarrheal
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep in a dry place away from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always start with the lowest effective dose and do not exceed the maximum daily limit.
2
Advise patients to use oral rehydration solutions along with this medicine to prevent dehydration.
3
Do not prescribe this medicine for diarrhea with fever or blood in stool without ruling out infection.
4
Warn patients about the risk of QT prolongation and serious arrhythmias with high doses.
5
Review all concomitant medications for CYP3A4 and P-glycoprotein inhibitors before prescribing.
6
In elderly patients, monitor closely for constipation and ileus.
7
Advise patients to stop the medicine and seek medical help if diarrhea persists beyond 48 hours.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Acute diarrhea
This medicine is commonly prescribed for this.
Likely Use
Chronic diarrhea
This medicine can be used for chronic diarrhea under medical supervision.
Likely Use
Fever
This medicine is not a primary fever reducer and should not be used if fever is present with diarrhea.
Not Primary
Bloody diarrhea
This medicine is contraindicated in bloody diarrhea.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is slowly and incompletely absorbed from the gastrointestinal tract. After oral administration, about 40% of the dose is absorbed, but due to extensive first-pass metabolism, the systemic bioavailability is only about 0.3%. Peak plasma concentrations are reached approximately 4 hours after ingestion.
DistributionThis medicine is highly bound to plasma proteins and has a large volume of distribution. It crosses the blood-brain barrier only minimally at therapeutic doses, but in overdose or with P-glycoprotein inhibition, it can accumulate in the central nervous system.
Protein BindingApproximately 95% bound to plasma proteins.
MetabolismThis medicine is extensively metabolized in the liver by cytochrome P450 enzymes, primarily CYP3A4 and CYP2C8. The main metabolite is desmethylloperamide, which is inactive.
Half-LifeThe elimination half-life of this medicine is approximately 9 to 14 hours, with a mean of about 11 hours.
ExcretionThis medicine and its metabolites are mainly excreted in the feces via bile, and a small amount is excreted in the urine.
BioavailabilityThe oral bioavailability of this medicine is approximately 0.3% due to extensive first-pass metabolism.
Onset of ActionThe antidiarrheal effect of this medicine usually begins within 1 hour after oral administration.
Peak Plasma TimePeak plasma concentration is reached approximately 4 hours after oral administration.
Duration of ActionThe antidiarrheal effect of this medicine can last up to 24 hours after a single dose, but this may vary depending on the individual and the severity of diarrhea.

How It Works

This medicine works by binding to mu-opioid receptors located in the myenteric plexus of the intestinal wall. This binding inhibits the release of acetylcholine and other neurotransmitters, which slows down peristaltic movements and prolongs the transit time of intestinal contents. As a result, more water and electrolytes are absorbed from the stool, and the anal sphincter tone increases, helping to reduce fecal urgency and incontinence. At recommended doses, this medicine has minimal absorption into the bloodstream and very little penetration into the brain, so it does not produce typical opioid effects like euphoria or respiratory depression. However, at very high doses or in overdose, it can enter the central nervous system and cause serious effects.

Mechanism Steps

1
Binding to mu-opioid receptors: This medicine binds to mu-opioid receptors in the myenteric plexus of the intestinal wall.
2
Inhibition of acetylcholine release: Activation of these receptors inhibits the release of acetylcholine and other excitatory neurotransmitters.
3
Reduced peristalsis: This leads to decreased peristaltic waves and slower movement of intestinal contents.
4
Increased fluid absorption: The longer transit time allows more water and electrolytes to be absorbed from the stool.
5
Increased sphincter tone: The medicine also increases the tone of the anal sphincter, reducing urgency and incontinence.

💡 How to Take allexit 2mg tablet

Strength: 2 mg immediate-release tablet

1Take this medicine orally with a glass of water.
2You can take it with or without food.
3Swallow the tablet whole. Do not crush, chew, or break it.
4Wash your hands before and after handling the tablet.
5Follow the dosage instructions exactly as prescribed by your doctor.

Dosage Information

Adult DosageFor acute diarrhea, the usual adult dose of this medicine is 4 mg (two 2 mg tablets) initially, followed by 2 mg after each loose stool, up to a maximum of 8 mg per day. For chronic diarrhea, the initial dose is 4 mg per day, which may be adjusted based on response, with a maximum of 16 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially constipation and central nervous system effects. Use with caution and start with the lowest effective dose. Dose must be individualized by a qualified clinician.
Renal ImpairmentNo specific dosage adjustment is recommended for renal impairment, but use with caution in severe renal impairment.
Hepatic ImpairmentIn patients with hepatic impairment, the clearance of this medicine may be reduced. Use with caution and consider dose reduction. Dose must be individualized by a qualified clinician.
Maximum Daily DoseThe maximum daily dose for adults is 8 mg for acute diarrhea and 16 mg for chronic diarrhea. Do not exceed these doses.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with or without food
Food does not significantly affect the absorption of this medicine.
Grapefruit juice
Avoid
May increase drug levels and risk of side effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of allexit 2mg tablet

✅ Common Side Effects

Constipation (Common (5-10%))
Increase fluid and fiber intake. If constipation persists or becomes severe, consult your doctor.
Abdominal cramps (Common (5-10%))
Usually resolves on its own. If severe or persistent, contact your doctor.
Nausea (Common (5-10%))
Take with food or milk to reduce nausea. If it continues, consult your doctor.
Dry mouth (Common (5-10%))
Sip water frequently. Chew sugar-free gum or use saliva substitutes if needed.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Drowsiness (Common (5-10%))
Avoid alcohol and other sedatives. Do not drive if drowsy.

🚨 Serious Side Effects

Paralytic ileus (Rare (<0.1%))
Seek immediate medical attention if you experience severe abdominal pain, bloating, and inability to pass stool or gas.
Toxic megacolon (Rare (<0.1%))
This is a medical emergency. Go to the hospital immediately if you have severe abdominal pain, fever, and a swollen abdomen.
Anaphylaxis (Rare (<0.1%))
Seek emergency help if you develop rash, itching, swelling of the face, lips, tongue, or throat, or difficulty breathing.
QT prolongation and torsades de pointes (Rare (<0.1%))
Call emergency services if you experience a fast, irregular, or pounding heartbeat, dizziness, or fainting.
Respiratory depression (Rare (<0.1%))
This is more common in overdose or in children. Seek immediate medical attention if breathing becomes slow or shallow.

⚠️ Rare Side Effects

Angioedema
Seek emergency medical care if you notice swelling of the face, lips, or throat.
Bullous eruption
Stop the medicine and consult a doctor immediately if you develop blisters or peeling skin.
Urinary retention
Consult your doctor if you are unable to urinate.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ketoconazole Major
Ritonavir Major
Quinidine Major
Amiodarone Major
Morphine Moderate
Cholestyramine Moderate
Antacids Minor
Grapefruit juice Moderate
Alcohol Moderate
Other opioids Moderate

🚨 Major Interactions

  • CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, ritonavir)
  • CYP2C8 inhibitors (e.g., gemfibrozil)
  • P-glycoprotein inhibitors (e.g., quinidine, verapamil)
  • QT-prolonging drugs (e.g., amiodarone, sotalol, haloperidol)

⚡ Moderate Interactions

  • Opioid analgesics
  • Anticholinergic drugs
  • Cholestyramine

🍷 Alcohol Interaction

Alcohol may increase the sedative effects of this medicine and can worsen dehydration caused by diarrhea. It is best to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to loperamide or any component of the formulation.","Children under 2 years of age.","Acute ulcerative colitis.","Bacterial enterocolitis caused by invasive organisms including Salmonella, Shigella, and Campylobacter.","Pseudomembranous colitis associated with broad-spectrum antibiotics.","Bloody diarrhea or diarrhea associated with high fever.","Severe hepatic impairment.","Paralytic ileus, abdominal distension, or toxic megacolon."]

⚠️ Warnings & Precautions

["Do not exceed the recommended dose. High doses can cause serious cardiac arrhythmias.","Avoid use in patients with acute diarrhea and fever or blood in stool.","Use with caution in patients with hepatic impairment.","Use with caution in elderly patients due to increased risk of constipation and ileus.","Avoid concomitant use with CYP3A4 inhibitors and P-glycoprotein inhibitors.","Do not use for more than 2 days for acute diarrhea without medical advice.","Keep out of reach of children. Accidental ingestion can be fatal.","This medicine may cause drowsiness. Avoid driving or operating machinery until you know how it affects you."]

🤱 Lactation Safety

This medicine is excreted in human milk in small amounts. It is generally considered safe for use during breastfeeding, but consult your doctor before use.

💊 Overdose Management

Overdose of this medicine can cause severe central nervous system depression, respiratory depression, and cardiac arrhythmias including QT prolongation and torsades de pointes. If overdose is suspected, seek emergency medical attention immediately. Treatment is supportive and may include activated charcoal, naloxone for opioid effects, and management of arrhythmias. Monitor ECG and vital signs closely.

⏰ Missed Dose

If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as directed by your doctor. Do not exceed the recommended dose because higher doses can cause serious heart rhythm problems. Drink plenty of fluids and use oral rehydration solutions to prevent dehydration. Avoid alcohol and other medications that cause drowsiness while taking this medicine. Do not use this medicine for more than 2 days for acute diarrhea without consulting a doctor. If diarrhea persists beyond 48 hours, or if you develop a fever or blood in your stool, stop the medicine and seek medical help. Keep this medicine out of reach of children and store it at room temperature away from moisture and heat.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to constipation and ileus with this medicine. Use with caution and monitor closely. Also, they may be more sensitive to the central nervous system effects.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

After surgery, diarrhea can occur due to various reasons. Do not self-medicate with this medicine without consulting your surgeon, as it may mask underlying complications.

🦷 Dental Procedures

This medicine does not have specific interactions with dental procedures. However, inform your dentist if you are taking this medicine, especially if you are scheduled for surgery.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated by drinking plenty of fluids and oral rehydration solutions.
🥗
Wash your hands frequently to prevent infections that cause diarrhea.
😴
Avoid foods that can trigger diarrhea, such as spicy or greasy foods.
💧
Practice good food hygiene to prevent traveler's diarrhea.
🧘
Get adequate rest to help your body recover.

🏋️ Exercise Considerations

Avoid strenuous exercise while you have diarrhea, as it can worsen dehydration. Rest and focus on rehydration. Once you recover, gradually resume your normal exercise routine.

🥗 Diet Recommendations

Follow the BRAT diet (bananas, rice, applesauce, toast) during acute diarrhea.
Avoid dairy products, caffeine, alcohol, and spicy foods.
Eat small, frequent meals.
Include probiotic-rich foods like yogurt once diarrhea subsides.
Stay hydrated with clear fluids and oral rehydration solutions.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is usually safe to continue light work, but take precautions to stay hydrated and comfortable.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if diarrhea persists for more than 48 hours, if you develop a fever, or if you see blood in your stool. Also stop if you experience severe constipation, abdominal pain, or any signs of an allergic reaction.

📅 Long-Term Use Effects

Long-term use of this medicine should be under medical supervision. Prolonged use may lead to constipation, abdominal discomfort, and dependence. Regular monitoring for cardiac effects is advised, especially in patients with underlying heart disease. Do not use for extended periods without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral rehydration therapy

Essential for preventing dehydration during diarrhea.

Evidence: Well-established
Probiotics

May help restore gut flora and reduce duration of diarrhea.

Evidence: Limited
Dietary modifications

Avoiding trigger foods and following a bland diet can help manage symptoms.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions with this medicine. However, if you have diarrhea due to an infection, consult your doctor about vaccination timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling with this medicine, carry it in its original packaging with the prescription label. Bring a copy of your prescription in case you need to show it at customs. Store it in a cool, dry place away from direct sunlight. If you are crossing time zones, continue taking your doses at the same intervals as prescribed. Do not pack it in checked luggage; keep it in your carry-on bag.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with acute diarrhea before a flight
She took this medicine as directed and noticed relief within an hour. She also drank plenty of fluids. She was advised not to take more than the recommended dose and to avoid alcohol.
💡 Lesson: Taking this medicine early and staying hydrated can help manage acute diarrhea effectively.
👤 A 60-year-old man with chronic diarrhea due to irritable bowel syndrome
He was prescribed this medicine for chronic diarrhea. He experienced mild constipation, which was managed by increasing fiber and fluids. He was monitored regularly for any cardiac symptoms.
💡 Lesson: Long-term use of this medicine requires monitoring for side effects and regular follow-up with a doctor.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 1 hour after taking it.

Q: Can I take this medicine with other medications?

A: Some medications can interact with this medicine. Always inform your doctor about all medicines you are taking.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe to take this medicine during pregnancy?

A: This medicine should be used during pregnancy only if clearly needed. Consult your doctor before use.

Q: Can I drink alcohol while taking this medicine?

A: It is best to avoid alcohol as it can increase drowsiness and dehydration.

Q: How long can I take this medicine?

A: For acute diarrhea, do not use for more than 2 days without medical advice. For chronic diarrhea, use only under medical supervision.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for allexit 2mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure all types of diarrhea.
    Fact: This medicine only treats symptoms and should not be used for diarrhea caused by bacteria or parasites, as it can worsen the infection.
  • Myth: This medicine is safe for children.
    Fact: This medicine is not safe for children under 2 years and should be used with caution in older children only under medical supervision.
  • Myth: Taking more of this medicine will stop diarrhea faster.
    Fact: Taking more than the recommended dose can cause serious heart rhythm problems and other severe side effects.

🔄 Alternative Options

Generic Alternatives

  • Loperamide 2 mg tablet

Brand Alternatives

  • Imodium
  • Lopamide

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","class":"Antidiarrheal","onset":"1 hour","duration":"Up to 24 hours","common_side_effects":"Constipation, cramps, dizziness"},{"medicine":"Diphenoxylate + Atropine","class":"Antidiarrheal","onset":"1-2 hours","duration":"3-4 hours","common_side_effects":"Drowsiness, dry mouth, constipation"},{"medicine":"Bismuth subsalicylate","class":"Antidiarrheal","onset":"1-2 hours","duration":"4-6 hours","common_side_effects":"Black tongue, black stool, constipation"}]

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