Aspirin + Atorvastatin + Clopidogrel Capsule: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unexplained muscle pain, tenderness, or weakness with fever
- Unusual bruising or bleeding that does not stop
- Confusion, slurred speech, or weakness on one side of the body
If experiencing severe symptoms, call emergency services immediately.
What is davaindia aspirin+atorvastatin+clopidogrel 150mg/20mg/75mg capsule used for?
This medicine is a combination of Aspirin 150 mg, Atorvastatin 20 mg, and Clopidogrel 75 mg used to prevent heart attacks and strokes in high-risk patients. It works by reducing blood clot formation and lowering cholesterol. It is taken once daily with food, and regular monitoring is required due to bleeding and liver risks.
- Generic Name: Aspirin (150mg) + Atorvastatin (20mg)
- Manufacturer: Davaindia Generic Pharmacy
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 davaindia aspirin+atorvastatin+clopidogrel 150mg/20mg/75mg capsule के बारे में (Hindi Summary)
उपयोग: यह दवा एस्पिरिन 150 मिलीग्राम, एटोरवास्टेटिन 20 मिलीग्राम और क्लोपिडोग्रेल 75 मिलीग्राम का संयोजन है। इसका उपयोग दिल के दौरे और स्ट्रोक को रोकने के लिए किया जाता है, खासकर उन रोगियों में जिन्हें पहले से हृदय रोग या स्ट्रोक हुआ है। यह रक्त के थक्के बनने को कम करता है और कोलेस्ट्रॉल को नियंत्रित करता है। यह दवा केवल डॉक्टर के पर्चे पर ही लेनी चाहिए और नियमित निगरानी आवश्यक है।
साइड इफेक्ट्स: आम दुष्प्रभावों में आसान चोट लगना, नाक से खून आना, पेट में जलन, मतली, सिरदर्द और मांसपेशियों में दर्द शामिल हैं। गंभीर दुष्प्रभावों में पेट या आंतों से खून बहना, मस्तिष्क में रक्तस्राव, गंभीर मांसपेशियों की समस्या, और एलर्जी प्रतिक्रियाएं शामिल हैं। यदि आपको काला मल, खून की उल्टी, अचानक कमजोरी, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को हमेशा डॉक्टर के निर्देशानुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन बिल्कुल न करें क्योंकि इससे रक्तस्राव और लीवर की समस्या बढ़ सकती है। कोई भी सर्जरी या दंत चिकित्सा से पहले अपने डॉक्टर को इस दवा के बारे में बताएं। बिना डॉक्टर की सलाह के कोई अन्य दवा शुरू या बंद न करें। नियमित रूप से रक्त परीक्षण करवाएं। यदि आपको असामान्य रक्तस्राव या चोट लगने में आसानी हो, तो तुरंत डॉक्टर को बताएं।
💊 davaindia aspirin+atorvastatin+clopidogrel 150mg/20mg/75mg capsule Uses & Benefits
[{"condition":"Acute Coronary Syndrome (ACS)","description":"Used in combination with other medicines to prevent further heart attacks and stent thrombosis in patients who have had a heart attack or unstable angina.","evidence":"Well-established"},{"condition":"Post-Myocardial Infarction","description":"Prescribed after a heart attack to reduce the risk of recurrent cardiovascular events, including another heart attack or stroke.","evidence":"Well-established"},{"condition":"Ischemic Stroke or Transient Ischemic Attack (TIA)","description":"Used for secondary prevention of stroke and transient ischemic attacks in patients with atherosclerotic disease.","evidence":"Well-established"},{"condition":"Peripheral Arterial Disease (PAD)","description":"May be used to reduce the risk of cardiovascular events in patients with peripheral arterial disease.","evidence":"Moderate"},{"condition":"Post-Stent Placement","description":"Essential after coronary stent implantation to prevent stent thrombosis, along with other antiplatelet agents as directed.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Primary Prevention in High-Risk Individuals","description":"Sometimes considered for primary prevention in patients with multiple risk factors but no established cardiovascular disease, though bleeding risk must be carefully weighed.","evidence":"Limited"},{"condition":"Antiphospholipid Syndrome","description":"May be used off-label in some patients with antiphospholipid syndrome to prevent thrombosis, but evidence is limited and specialist supervision is required.","evidence":"Limited"}]
Primary treatment for: Cardiovascular disease prevention (secondary prevention after heart attack or stroke)
Also treats: Acute coronary syndrome, Ischemic stroke, Transient ischemic attack, Peripheral arterial disease, Coronary artery disease, Hyperlipidemia
📋 Drug Information
| Generic Name(s) | Aspirin (150mg) + Atorvastatin (20mg) |
| Brand Name | davaindia aspirin+atorvastatin+clopidogrel 150mg/20mg/75mg capsule |
| Manufacturer | Davaindia Generic Pharmacy |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children and pets. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | Not established from the available information. Guidelines from the World Health Organization may recommend antiplatelet therapy and statins for secondary prevention of cardiovascular disease, but specific recommendations for this fixed-dose combination are not available. |
| ICMR Guideline | Not established from the available information. The Indian Council of Medical Research may have guidelines on the use of antiplatelet and lipid-lowering therapy, but specific recommendations for this combination are not available. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines three active ingredients with complementary mechanisms. Aspirin irreversibly inhibits cyclooxygenase-1 (COX-1) and COX-2 enzymes, reducing thromboxane A2 production, which is a potent platelet aggregator and vasoconstrictor. Clopidogrel is a prodrug that irreversibly inhibits the P2Y12 ADP receptor on platelets, preventing ADP-mediated platelet activation and aggregation. Atorvastatin competitively inhibits HMG-CoA reductase, the rate-limiting enzyme in cholesterol synthesis, leading to upregulation of LDL receptors and increased clearance of LDL cholesterol from the blood. Together, these actions reduce thrombus formation and slow the progression of atherosclerosis.
Mechanism Steps
💡 How to Take davaindia aspirin+atorvastatin+clopidogrel 150mg/20mg/75mg capsule
Strength: Capsule containing Aspirin 150 mg, Atorvastatin 20 mg, and Clopidogrel 75 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one capsule taken orally once daily, preferably with food. However, the exact dose and duration must be individualized by a qualified clinician based on the indication, patient's age, weight, renal and hepatic function, and other medications. Do not adjust the dose without medical advice. For acute coronary syndrome, a loading dose of clopidogrel and aspirin may be given separately before starting this combination. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially increased bleeding risk and muscle toxicity. Dose adjustments may be necessary based on renal and hepatic function. Regular monitoring is recommended. Consult your doctor for individualized dosing. |
| Renal Impairment | Use with caution in patients with renal impairment. No specific dose adjustment is established for this combination, but individual components may require adjustment. Clopidogrel and aspirin do not require dose adjustment in mild to moderate renal impairment, but atorvastatin should be used with caution in severe renal impairment. Consult your doctor. |
| Hepatic Impairment | Contraindicated in patients with active liver disease or unexplained persistent transaminase elevations. In patients with mild to moderate hepatic impairment, atorvastatin should be used with caution and dose reduction may be considered. Aspirin and clopidogrel should be used with caution. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose for this specific combination is one capsule (Aspirin 150 mg + Atorvastatin 20 mg + Clopidogrel 75 mg) once daily. Do not exceed the prescribed dose. Higher doses of individual components may be used separately under medical supervision, but this fixed-dose combination should not be exceeded. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of davaindia aspirin+atorvastatin+clopidogrel 150mg/20mg/75mg capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Clarithromycin | Major | |
| Omeprazole | Major | |
| Corticosteroids | Moderate | |
| SSRIs | Moderate | |
| Gemfibrozil | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Warfarin
- NSAIDs (e.g., ibuprofen, naproxen)
- Other antiplatelet agents (e.g., ticagrelor, prasugrel)
- CYP3A4 inhibitors (e.g., clarithromycin, itraconazole, ritonavir)
- CYP2C19 inhibitors (e.g., omeprazole, esomeprazole)
⚡ Moderate Interactions
- Corticosteroids
- SSRIs (e.g., fluoxetine, sertraline)
- Fibrates (e.g., gemfibrozil)
- Digoxin
- Oral contraceptives
🍷 Alcohol Interaction
Alcohol should be completely avoided while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding due to aspirin and clopidogrel, and it also increases the risk of liver damage from atorvastatin. Additionally, alcohol can worsen the lipid profile and reduce the effectiveness of atorvastatin.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active pathological bleeding such as peptic ulcer or intracranial haemorrhage","Hypersensitivity to aspirin, clopidogrel, atorvastatin, or any component of the formulation","Severe liver disease or unexplained persistent elevations of serum transaminases","Active peptic ulcer disease","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Concurrent use with warfarin or other anticoagulants (relative contraindication)","Pregnancy (especially third trimester) and breastfeeding"]
⚠️ Warnings & Precautions
["Increased risk of bleeding: This medicine increases the risk of serious bleeding, including gastrointestinal and intracranial haemorrhage. Monitor closely.","Discontinuation before surgery: Stop this medicine 5-7 days before any surgery or dental procedure to reduce bleeding risk, but only after consulting your doctor.","Liver toxicity: Atorvastatin can cause liver enzyme elevations. Monitor liver function tests.","Muscle toxicity: Atorvastatin can cause myopathy and rhabdomyolysis. Report unexplained muscle pain, tenderness, or weakness.","Renal impairment: Use with caution; dose adjustments may be needed.","Hypersensitivity: Severe allergic reactions can occur. Discontinue and seek immediate medical help if suspected.","Thrombotic thrombocytopenic purpura (TTP): Rare but serious. Seek immediate care if symptoms occur.","Avoid alcohol: Increases risk of bleeding and liver toxicity.","Grapefruit juice: Avoid or limit due to interaction with atorvastatin.","Regular monitoring: Blood tests are essential to monitor safety and efficacy."]
🤱 Lactation Safety
Not established from the available information. Aspirin, clopidogrel, and atorvastatin may pass into breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother. Consult your doctor.
💊 Overdose Management
Overdose of this medicine may cause severe bleeding, gastrointestinal irritation, and potentially liver or muscle toxicity. If you suspect an overdose, seek emergency medical attention immediately. Treatment is supportive and may include gastric lavage, activated charcoal, and administration of vitamin K or platelet transfusions for bleeding. There is no specific antidote for clopidogrel or atorvastatin. Monitor vital signs, bleeding parameters, liver enzymes, and renal function.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose (less than 12 hours away), skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Always take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the capsule; swallow it whole with a full glass of water. Take it at the same time each day, preferably with food to reduce stomach irritation. Avoid alcohol completely while on this medicine, as it increases the risk of stomach bleeding and liver problems. Inform all your healthcare providers, including dentists, that you are taking this medicine before any procedure or surgery. Do not start or stop any other medication, including over-the-counter pain relievers, without consulting your doctor. Regular blood tests to monitor bleeding time, liver function, and cholesterol levels are essential. If you miss a dose, follow the missed dose instructions provided. Never double the dose to make up for a missed one. Store in a cool, dry place away from direct sunlight and out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients (above 65 years) are at higher risk of bleeding, especially gastrointestinal and intracranial bleeding, and may be more susceptible to muscle toxicity from atorvastatin. Dose adjustments may be necessary based on renal and hepatic function. Regular monitoring of bleeding signs, liver enzymes, and kidney function is recommended. Falls prevention is important to reduce bleeding risk.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy. If you are planning to become pregnant, consult your doctor well in advance. They may switch you to alternative treatments that are safer during pregnancy. Use effective contraception while taking this medicine. If you become pregnant while on this medicine, contact your doctor immediately.
🏥 Post-Surgery Considerations
This medicine increases bleeding risk, so it is usually stopped 5-7 days before any surgery, including dental procedures. However, this decision must be made by your surgeon and cardiologist. After surgery, your doctor will advise when it is safe to restart. Do not restart on your own. If you undergo emergency surgery, inform the surgical team about this medicine immediately.
🦷 Dental Procedures
Before any dental procedure, inform your dentist that you are taking this medicine. It may need to be stopped 5-7 days before the procedure to reduce bleeding risk. Your dentist may consult with your doctor. For minor procedures, your dentist may take extra precautions to control bleeding. Do not stop the medicine without medical advice.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may be more prone to bleeding and bruising. Avoid contact sports or activities that carry a high risk of injury. If you experience any bleeding or unusual bruising, consult your doctor. Regular moderate exercise is encouraged, but always follow your doctor's advice regarding any restrictions.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may increase your risk of bleeding, so you should be cautious with activities that could cause injury. It generally does not affect your ability to drive or operate machinery, but if you experience dizziness or vision changes, avoid these activities. Inform your employer about your condition and medicine, especially if your job involves physical risks. Regular follow-up appointments may require time off work.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor may consider stopping it if you develop serious side effects such as severe bleeding, liver injury, or muscle toxicity, or if your risk of bleeding outweighs the benefits. In some cases, it may be stopped after a certain period, such as 12 months after stent placement, but this decision must be made by your cardiologist. Never stop abruptly on your own.
📅 Long-Term Use Effects
Long-term use of this medicine is often necessary for secondary prevention of cardiovascular events. Regular monitoring of bleeding parameters, liver function, kidney function, and lipid profile is essential. Prolonged use may increase the risk of gastrointestinal bleeding, and rarely, liver or muscle toxicity. Patients should be reviewed periodically to assess the risk-benefit ratio and to adjust therapy as needed. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
May be used if statin is not tolerated or not needed.
Evidence: Well-establishedMay be used in patients with lower risk or who cannot tolerate dual therapy.
Evidence: Well-establishedFor patients with mild risk, lifestyle changes may be sufficient, but this is not a substitute for medicine in high-risk patients.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, if you are due for any vaccination, especially those that may cause bleeding (e.g., intramuscular injections), inform the healthcare provider about your medicine. They may use a smaller needle or apply pressure to reduce bleeding risk. Live vaccines are generally safe, but consult your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or exposure to extreme temperatures. If crossing time zones, continue taking your dose at the same local time as usual; no adjustment is typically needed for once-daily dosing. Store away from direct sunlight and moisture. Check customs regulations for carrying prescription medicines in your destination country. Carry enough supply for your entire trip and a little extra in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The antiplatelet effect starts within hours, but the full protective effect against heart attack and stroke develops over days to weeks. The cholesterol-lowering effect begins within 2 weeks and reaches maximum at 4-6 weeks.
A: No, you should never stop this medicine without consulting your doctor. Stopping suddenly can increase the risk of heart attack or stroke. Your doctor will decide if and when it is safe to stop.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose (less than 12 hours away), skip the missed dose and continue with your regular schedule. Do not double dose.
A: You should avoid taking NSAIDs like ibuprofen or naproxen, as they can increase bleeding risk and reduce the effect of aspirin. Consult your doctor before taking any painkiller.
A: This medicine is generally not recommended during pregnancy, especially in the third trimester, due to risk of bleeding and potential harm to the fetus. Consult your doctor immediately if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for davaindia aspirin+atorvastatin+clopidogrel 150mg/20mg/75mg capsule
View AllAlternative brands with exact same active ingredient:
-
atorise asp 20mg/150mg capsuleCarise Pharmaceuticals Pvt Ltd ₹22.00 47.6% CHEAPER
-
davaindia atorvastatin+aspirin 20mg/150mg capsuleDavaindia Generic Pharmacy ₹23.00 45.2% CHEAPER
-
tonact-asp 20/150 capsuleLupin Ltd ₹43.40 3.3% COSTLIER
-
ecosprin av 150/20 capsuleUSV Ltd ₹73.45 74.9% COSTLIER
-
jovastatin ap 20mg/150mg capsuleJohnlee Pharmaceuticals Pvt Ltd ₹75.94 80.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without a prescription.
Fact: This is a prescription-only medicine and should never be taken without medical supervision due to serious bleeding risks. - Myth: Once cholesterol is normal, I can stop this medicine.
Fact: Even if cholesterol is normal, the antiplatelet effect is still needed to prevent clots. Stopping suddenly can increase the risk of heart attack or stroke. - Myth: This medicine is safe to take with any other medicine.
Fact: It interacts with many medicines, including painkillers, blood thinners, and certain antibiotics. Always consult your doctor before adding any new medicine. - Myth: This medicine can be taken on an empty stomach.
Fact: It should be taken with food to reduce stomach irritation and risk of bleeding. - Myth: Alcohol in moderation is safe with this medicine.
Fact: Alcohol increases the risk of gastrointestinal bleeding and liver damage. It is best to avoid alcohol completely.
🔄 Alternative Options
Generic Alternatives
- Aspirin + Atorvastatin + Clopidogrel (generic)
Brand Alternatives
- Davaindia Aspirin+Atorvastatin+Clopidogrel 150mg/20mg/75mg Capsule