Amlox HP 750mg/40mg/500mg Kit: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools.
- Severe abdominal pain that does not go away.
- Difficulty breathing or swelling of the face, lips, or throat.
- Severe watery diarrhoea with fever or abdominal cramps.
- Yellowing of the skin or eyes, or dark urine.
- Unusual bruising or bleeding.
- Decreased urine output or swelling in the legs.
If experiencing severe symptoms, call emergency services immediately.
What is amlox hp 750mg/40mg/500mg kit used for?
This medicine is a prescription kit containing amoxycillin 750 mg and pantoprazole 40 mg. It is used to treat Helicobacter pylori infection, which causes stomach ulcers and gastritis. It works by killing the bacteria and reducing stomach acid. Take it exactly as prescribed, usually twice daily before meals for 10 to 14 days.
- Generic Name: Amoxycillin + Pantoprazole
- Manufacturer: Leeford Healthcare Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 amlox hp 750mg/40mg/500mg kit के बारे में (Hindi Summary)
उपयोग: यह दवा एमोक्सिसिलिन और पैंटोप्राजोल का संयोजन है, जिसका उपयोग हेलिकोबैक्टर पाइलोरी (H. pylori) संक्रमण के इलाज के लिए किया जाता है। यह संक्रमण पेट के अल्सर और गैस्ट्राइटिस का कारण बन सकता है। यह दवा बैक्टीरिया को मारती है और पेट में एसिड को कम करती है, जिससे पेट की परत को आराम मिलता है। इसे डॉक्टर के निर्देशानुसार, आमतौर पर 10 से 14 दिनों तक, दिन में दो बार भोजन से पहले लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, मतली, पेट दर्द, सिरदर्द, और मुँह में धातु जैसा स्वाद शामिल हैं। कभी-कभी त्वचा पर दाने, खुजली, या यीस्ट संक्रमण भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको साँस लेने में कठिनाई, चेहरे या गले में सूजन, गंभीर दस्त, या पीलिया जैसे लक्षण दिखें, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और पूरा कोर्स पूरा करें, भले ही आपको कुछ दिनों में आराम महसूस होने लगे। इसे भोजन से 30 से 60 मिनट पहले पानी के साथ निगलें। शराब का सेवन न करें क्योंकि इससे पेट में जलन बढ़ सकती है। अगर आप गर्भवती हैं, स्तनपान करा रही हैं, या कोई अन्य दवा ले रही हैं, तो डॉक्टर को बताएं। इस दवा को किसी और के साथ साझा न करें।
💊 amlox hp 750mg/40mg/500mg kit Uses & Benefits
- [{"condition":"Helicobacter pylori eradication","description":"This medicine is used as part of a combination regimen to eliminate H.
- pylori from the stomach, which helps heal peptic ulcers and reduces the risk of ulcer recurrence.","evidence":"Well-established"},{"condition":"Peptic ulcer disease associated with H.
- pylori","description":"By eradicating the bacterium and reducing acid production, this kit supports ulcer healing and lowers the chance of bleeding or perforation.","evidence":"Well-established"},{"condition":"Gastritis linked to H.
- pylori","description":"Pantoprazole reduces acid-related inflammation while amoxycillin targets the underlying bacterial infection.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Functional dyspepsia with H. pylori infection","description":"Sometimes prescribed when dyspepsia symptoms persist and H. pylori is detected, although evidence for benefit is less consistent than for peptic ulcer disease.","evidence":"Limited"}]
Primary treatment for: Helicobacter pylori infection
Also treats: Peptic ulcer disease, Chronic gastritis, Gastro-oesophageal reflux disease (GERD) with H. pylori
📋 Drug Information
| Generic Name(s) | Amoxycillin + Pantoprazole |
| Brand Name | Amlox HP 750mg/40mg/500mg Kit |
| Manufacturer | Leeford Healthcare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Antibiotic + Proton Pump Inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C, away from direct sunlight and moisture. Keep the capsules in their original blister pack or container until it is time to take them. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the packaging. |
| WHO Guideline | The World Health Organization lists amoxycillin and pantoprazole among essential medicines, but specific H. pylori eradication regimens vary by region and resistance patterns. Always follow your local guidelines and your doctor's prescription. |
| ICMR Guideline | The Indian Council of Medical Research recommends testing for H. pylori in patients with dyspepsia and treating with a combination of a proton-pump inhibitor, amoxycillin, and clarithromycin or metronidazole for 14 days in areas of low clarithromycin resistance. This kit provides amoxycillin and pantoprazole, and may be part of a broader regimen as prescribed by your doctor. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Amoxycillin is a beta-lactam antibiotic that binds to penicillin-binding proteins on the bacterial cell wall, preventing the cross-linking of peptidoglycan strands. This weakens the cell wall and leads to bacterial lysis and death, especially in actively dividing organisms. Pantoprazole is a proton-pump inhibitor that accumulates in the acidic environment of the stomach's parietal cells and irreversibly blocks the hydrogen-potassium ATPase enzyme, the final step in gastric acid secretion. By suppressing acid, pantoprazole raises the stomach pH, which protects amoxycillin from acid degradation and creates a more favourable environment for the antibiotic to act against H. pylori.
Mechanism Steps
💡 How to Take amlox hp 750mg/40mg/500mg kit
Strength: Kit containing amoxycillin 750 mg and pantoprazole 40 mg capsules.
Dosage Information
| Adult Dosage | The usual adult dose for H. pylori eradication is one kit taken twice daily, typically for 10 to 14 days. Each kit contains amoxycillin 750 mg and pantoprazole 40 mg. The capsules should be swallowed whole with water, preferably 30 to 60 minutes before a meal. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and local resistance patterns. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially kidney-related effects from amoxycillin and magnesium or vitamin B12 depletion from pantoprazole. Dose adjustments may be needed based on kidney function. Regular monitoring is advised. |
| Renal Impairment | In patients with kidney impairment, the dose of amoxycillin may need to be reduced, and the dosing interval extended. Pantoprazole dose adjustment is not usually required, but caution is advised in severe kidney disease. Consult your doctor for personalized dosing. |
| Hepatic Impairment | In patients with mild to moderate liver impairment, no dose adjustment is usually needed. In severe liver impairment, amoxycillin should be used with caution, and pantoprazole dose may need to be reduced. Consult your doctor for personalized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is amoxycillin 1500 mg and pantoprazole 80 mg, taken as two kits per day. Do not exceed this dose unless specifically instructed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of amlox hp 750mg/40mg/500mg kit
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Methotrexate | Major | |
| Warfarin | Major | |
| Rilpivirine | Major | |
| Clopidogrel | Major | |
| Allopurinol | Moderate | |
| Oral contraceptives | Moderate | |
| Ketoconazole | Moderate | |
| Atazanavir | Moderate | |
| Antacids | Minor | |
| Iron supplements | Minor |
🚨 Major Interactions
- Methotrexate
- Warfarin
- Rilpivirine
- Clopidogrel
⚡ Moderate Interactions
- Allopurinol
- Oral contraceptives
- Ketoconazole and itraconazole
- Atazanavir
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. It can increase stomach irritation, worsen gastritis symptoms, and may reduce the effectiveness of the antibiotic. Alcohol can also increase the risk of liver-related side effects and dehydration from diarrhoea.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to amoxycillin, other penicillins, cephalosporins, or any component of this medicine.","Concomitant use with rilpivirine.","History of severe allergic reaction to any beta-lactam antibiotic.","Use in patients with rare hereditary problems of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption.","Not for use in children unless specifically prescribed by a pediatrician."]
⚠️ Warnings & Precautions
["Before starting this medicine, tell your doctor if you are allergic to penicillin or any other antibiotics.","Inform your doctor if you have kidney or liver disease, as dose adjustments may be needed.","This medicine may reduce the effectiveness of oral contraceptives; use an additional barrier method during treatment.","Prolonged use of pantoprazole may increase the risk of bone fractures, low magnesium, and vitamin B12 deficiency.","Do not use this medicine for viral infections like the common cold or flu, as it will not help and may cause harm.","If you develop severe diarrhoea, contact your doctor before taking any anti-diarrhoeal medicine, as it could be a sign of a serious intestinal infection.","Complete the full course of antibiotics as prescribed, even if you feel better, to prevent antibiotic resistance."]
🤱 Lactation Safety
Amoxycillin passes into breast milk in small amounts and is generally considered compatible with breastfeeding, but it may cause diarrhoea or thrush in the nursing infant. Pantoprazole also passes into breast milk in small amounts, and its safety during breastfeeding is not fully established. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, diarrhoea, and abdominal pain. In severe cases, amoxycillin can cause crystalluria, seizures, or kidney failure, especially in people with kidney disease. Pantoprazole overdose may cause drowsiness, blurred vision, and confusion. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and may include activated charcoal if the overdose is recent, and haemodialysis in severe cases.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as your doctor prescribes, usually for 10 to 14 days, and complete the full course even if you feel better after a few days. Swallow the capsules whole with a glass of water, ideally 30 to 60 minutes before a meal, because pantoprazole works best on an empty stomach. Do not crush, chew, or open the capsules unless your doctor or pharmacist tells you to. Avoid alcohol during treatment because it can worsen stomach irritation and may reduce the effectiveness of the antibiotic. Inform your doctor about all other medicines you take, especially blood thinners, methotrexate, clopidogrel, or antacids, as this kit can interact with them. If you are pregnant, planning pregnancy, or breastfeeding, speak to your doctor before starting this medicine. Do not share this medicine with anyone else, and do not save leftover antibiotics for future use.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the side effects of this medicine, particularly kidney-related effects from amoxycillin and magnesium or vitamin B12 depletion from pantoprazole. Kidney function should be assessed before and during treatment, and doses may need adjustment. Regular monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss this medicine with your doctor before starting. Amoxycillin is generally considered safe, but pantoprazole should be used only if clearly needed. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
If you have recently had surgery, inform your surgeon and anaesthesiologist that you are taking this medicine. It may interact with other medications used during surgery. Your doctor will advise you on whether to continue or temporarily stop the medicine.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. Antibiotics can affect the balance of bacteria in the mouth and may interact with other medications used during dental work. Your dentist may recommend postponing non-urgent procedures until you finish the course.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, if you experience dizziness, fatigue, or abdominal pain, avoid strenuous activities and consult your doctor. Stay well hydrated, especially if you have diarrhoea.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or headache in some people. If you experience these effects, avoid driving or operating heavy machinery until you know how the medicine affects you. Most people can continue their normal daily activities while taking this medicine.
🛑 When to Stop This Medicine
Do not stop taking this medicine before completing the full course prescribed by your doctor, even if you feel better. Stopping early can lead to incomplete eradication of the infection and antibiotic resistance. If you experience severe side effects, contact your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of pantoprazole, the acid-reducing component of this medicine, has been associated with an increased risk of bone fractures, low magnesium levels, vitamin B12 deficiency, and a possible increased risk of certain infections. Amoxycillin is usually used for a short course, so long-term effects are not a concern when taken as prescribed. If you need to take acid-reducing medicine for a long time, your doctor may monitor your magnesium and vitamin B12 levels and adjust your treatment accordingly.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Probiotics may help reduce antibiotic-associated diarrhoea and restore gut flora during H. pylori treatment.
Evidence: ModerateAvoiding spicy and acidic foods can help reduce stomach irritation while the infection heals.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions with this medicine. However, if you are due for any vaccinations, inform your doctor that you are taking antibiotics. In general, antibiotics do not interfere with vaccine effectiveness, but it is always best to consult your healthcare provider.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your hand luggage to avoid loss or exposure to extreme temperatures. Store at room temperature and away from direct sunlight. If crossing time zones, continue taking the medicine at the same intervals as prescribed; you may need to adjust the timing gradually. Check the customs regulations of your destination country regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within a few days, but it is important to complete the full course of 10 to 14 days to ensure the infection is fully treated.
A: Take this medicine 30 to 60 minutes before a meal for best effect. If it upsets your stomach, consult your doctor.
A: If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double dose.
A: Amoxycillin is generally considered safe in pregnancy, but pantoprazole should be used only if clearly needed. Consult your doctor before taking this medicine.
A: It is best to avoid alcohol as it can worsen stomach irritation and may reduce the effectiveness of the antibiotic.
🤔 Common Patient Concerns
🔄 Substitutes for amlox hp 750mg/40mg/500mg kit
View AllAlternative brands with exact same active ingredient:
-
stayhappi amoxycillin+pantoprazole+clarithromycin 750mg/40mg/500mg kitSarvagunaushdhi Pvt Ltd ₹84.38 37.5% CHEAPER
-
pleze-hp kitLifeline Remedies India Pvt Ltd ₹140.53 4.1% COSTLIER
-
cure-hp kitNGS Biotech Pvt Ltd ₹150.00 11.1% COSTLIER
-
evoxil-hp kitLeeford Healthcare Ltd ₹152.80 13.2% COSTLIER
-
panto-clam kitRlv Lifesciences Private Limited ₹159.38 18.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any stomach infection.
Fact: This medicine is specifically for Helicobacter pylori infection and should not be used for other types of stomach infections without medical advice. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full course as prescribed, even if symptoms improve, to ensure the bacteria are completely eradicated and to prevent resistance. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol can worsen stomach irritation and may reduce the effectiveness of the antibiotic. It is best to avoid alcohol during treatment. - Myth: This medicine can be taken for a common cold or flu.
Fact: This medicine is an antibiotic and acid reducer, and it does not treat viral infections like the common cold or flu.
🔄 Alternative Options
Generic Alternatives
- Amoxycillin + Pantoprazole generic kit
Brand Alternatives
- Amlox HP 750mg/40mg/500mg Kit