amrox-ls syrup - Ambroxol (30mg) + Levosalbutamol (1mg) medicine

Amrox-LS Syrup: Complete Guide to Uses, Dosage, and Safety

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🏭 Leeford Healthcare Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for the combination in respiratory conditions with mucus and bronchospasm.
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe chest pain or palpitations
  • Difficulty breathing or worsening of breathlessness after taking the medicine
  • Swelling of the face, lips, tongue, or throat
  • Severe skin rash, blisters, or peeling skin
  • Muscle weakness or cramps with irregular heartbeat
  • Blood in sputum or vomit
  • Yellowing of eyes or skin
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is amrox-ls syrup used for?

This medicine is a combination syrup containing ambroxol (30 mg) and levosalbutamol (1 mg) per 5 mL. It is used to treat productive cough with bronchospasm by thinning mucus and opening airways. It is available by prescription only and should be taken exactly as directed by a doctor.

  • Generic Name: Ambroxol + Levosalbutamol
  • Manufacturer: Leeford Healthcare Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 amrox-ls syrup के बारे में (Hindi Summary)

उपयोग: यह दवा एक प्रिस्क्रिप्शन सिरप है जिसमें एम्ब्रोक्सोल (30 मिलीग्राम) और लेवोसाल्बुटामोल (1 मिलीग्राम) प्रति 5 मिलीलीटर होता है। इसका उपयोग बलगम वाली खांसी और सांस लेने में कठिनाई के इलाज के लिए किया जाता है, जो ब्रोंकोस्पाज्म के कारण होती है। यह दवा बलगम को पतला करती है और श्वास नलियों को फैलाकर सांस लेना आसान बनाती है। यह अस्थमा, ब्रोंकाइटिस और सीओपीडी जैसी स्थितियों में मदद करती है। इसका सेवन डॉक्टर के निर्देशानुसार ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में जी मिचलाना, सिरदर्द, चक्कर आना, हाथ-पैर कांपना और दिल की धड़कन तेज होना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि सांस लेने में तकलीफ, सीने में दर्द, चेहरे या गले में सूजन, या त्वचा पर गंभीर दाने हों तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। मात्रा बढ़ाएं नहीं। उपयोग से पहले बोतल को अच्छी तरह हिलाएं और मापने वाले कप से सही मात्रा लें। यदि आपको हृदय रोग, उच्च रक्तचाप, मधुमेह, थायरॉइड या गुर्दे/यकृत की समस्या है तो डॉक्टर को बताएं। दवा लेने के बाद चक्कर आने पर वाहन न चलाएं। बच्चों की पहुंच से दूर रखें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 amrox-ls syrup Uses & Benefits

[{"condition":"Productive cough with bronchospasm","description":"Helps loosen thick mucus and relaxes airway muscles, making it easier to cough out sputum and breathe.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Used to relieve cough and wheezing associated with acute inflammation of the bronchi.","evidence":"Well-established"},{"condition":"Chronic obstructive pulmonary disease (COPD)","description":"Provides symptomatic relief of breathlessness and helps clear secretions in COPD patients.","evidence":"Well-established"},{"condition":"Asthma with mucus plugging","description":"May be used as an add-on to standard asthma therapy when thick secretions are a problem.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Prevention of respiratory distress in preterm infants","description":"Ambroxol has been studied off-label for lung maturation, but this is not a standard use for this syrup.","evidence":"Limited"}]

Primary treatment for: Productive cough with bronchospasm

Also treats: Acute bronchitis, Chronic obstructive pulmonary disease (COPD), Asthma

📋 Drug Information

Generic Name(s)Ambroxol + Levosalbutamol
Brand NameAscoril LS Junior Syrup
ManufacturerLeeford Healthcare Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic + Beta-2 Adrenergic Agonist
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Do not freeze. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture, or as printed on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this medicine only when there is clear evidence of bronchospasm with thick mucus; avoid use for dry cough.
2
Advise patients to shake the bottle well before each dose to ensure uniform mixing of the active ingredients.
3
Warn patients about the possibility of tremor and palpitations, especially at higher doses, and reassure them that these often subside.
4
Monitor heart rate and blood pressure in elderly patients and those with cardiovascular disease.
5
Check serum potassium levels if the patient is also on diuretics or corticosteroids, as levosalbutamol can cause hypokalemia.
6
Instruct patients not to combine this medicine with other over-the-counter cough syrups without medical advice.
7
For diabetic patients, recommend monitoring blood glucose more frequently as levosalbutamol may increase blood sugar.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Productive cough with thick mucus
This medicine is commonly prescribed for this.
Likely Use
Wheezing and breathlessness
Levosalbutamol helps relieve bronchospasm.
Likely Use
Dry cough
This medicine is not effective for dry cough without mucus.
Not Primary
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmbroxol is rapidly absorbed from the gastrointestinal tract after oral administration. Levosalbutamol is also well absorbed orally, although oral bioavailability is lower than inhaled routes due to first-pass metabolism. Peak plasma levels of ambroxol are typically reached within 1 to 3 hours. The exact absorption characteristics of this fixed-dose combination syrup are not established from the available information.
DistributionAmbroxol distributes widely into body tissues and crosses the blood-brain barrier and placental barrier. It is also excreted in breast milk. Levosalbutamol distributes into the lungs and other tissues, with a volume of distribution that is not well characterized for the oral syrup. Protein binding information for the combination is not established from the available information.
Protein BindingAmbroxol is approximately 80-90% bound to plasma proteins. Levosalbutamol protein binding is not well established for the oral route. The protein binding of this specific combination product is not established from the available information.
MetabolismAmbroxol is metabolized in the liver primarily by conjugation to glucuronic acid and sulfate, forming inactive metabolites. Levosalbutamol undergoes extensive first-pass metabolism in the liver, mainly by sulfation to inactive sulfate conjugates. The exact metabolic pathways for this combination syrup are not fully established from the available information.
Half-LifeThe elimination half-life of ambroxol is approximately 7 to 12 hours. Levosalbutamol has a plasma half-life of about 3 to 4 hours. The half-life of the combination product may vary based on individual patient factors and is not established from the available information.
ExcretionAmbroxol and its metabolites are primarily excreted in the urine, with a small amount in feces. Levosalbutamol and its metabolites are mainly excreted in the urine. The exact excretion profile of this combination syrup is not established from the available information.
BioavailabilityThe oral bioavailability of ambroxol is approximately 70-80% due to first-pass metabolism. Levosalbutamol has a lower oral bioavailability, reported to be around 40-50% in some studies. The bioavailability of this specific fixed-dose combination syrup is not established from the available information.
Onset of ActionThe bronchodilator effect of levosalbutamol typically begins within 15 to 30 minutes after oral administration. Ambroxol's mucolytic effect may take several hours to become noticeable. The exact onset of action for this combination syrup is not established from the available information.
Peak Plasma TimePeak plasma concentrations of ambroxol are reached about 1 to 3 hours after oral intake. Levosalbutamol peaks around 1 to 2 hours after oral administration. The peak plasma time for this combination product is not established from the available information.
Duration of ActionThe bronchodilator effect of levosalbutamol usually lasts for 4 to 6 hours after oral dosing. Ambroxol's mucolytic effect may persist for several hours. The duration of action of this combination syrup is not established from the available information.

How It Works

This medicine combines two active ingredients with complementary actions. Ambroxol acts as a mucolytic and secretolytic agent. It reduces the viscosity of mucus by breaking down acidic mucopolysaccharide fibers and stimulates the production of surfactant, which helps keep airways open. Levosalbutamol is the active R-enantiomer of salbutamol. It selectively stimulates beta-2 adrenergic receptors on the smooth muscle cells of the airways, which increases cyclic AMP levels and leads to relaxation of the bronchial muscles. This results in widening of the airways and easier breathing. Together, these actions help clear mucus and relieve bronchospasm.

Mechanism Steps

1
Levosalbutamol binds beta-2 receptors: Levosalbutamol selectively binds to beta-2 adrenergic receptors on the smooth muscle of the airways.
2
Increase in cyclic AMP: This binding activates adenylate cyclase, raising cyclic AMP levels inside the muscle cells.
3
Bronchial smooth muscle relaxation: The rise in cyclic AMP causes the bronchial muscles to relax, widening the airways and easing breathing.
4
Ambroxol thins mucus: Ambroxol breaks down the structure of thick mucus and stimulates surfactant production, making secretions less sticky.
5
Improved mucus clearance: The thinner mucus is easier for the cilia and cough to move out of the airways, reducing cough and congestion.

💡 How to Take amrox-ls syrup

Strength: Each 5 mL of syrup contains Ambroxol 30 mg and Levosalbutamol 1 mg.

1Shake the bottle well before each use.
2Measure the prescribed dose using the measuring cup or spoon provided.
3Take the medicine orally, with or without food.
4If it upsets your stomach, take it with a meal or a glass of milk.
5After taking, rinse your mouth with water to prevent any aftertaste.
6Wash the measuring cup thoroughly after each use.
7Close the bottle tightly and store as directed.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 5 to 10 mL taken two to three times a day, or as directed by your doctor. The exact dose depends on the severity of your condition, your age, and your kidney and liver function. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of levosalbutamol, especially increased heart rate and tremor. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentIn patients with severe renal impairment, dose reduction may be necessary. Consult your doctor for appropriate dosing.
Hepatic ImpairmentIn patients with severe hepatic impairment, use with caution and consider dose reduction. Consult your doctor for appropriate dosing.
Maximum Daily DoseThe maximum recommended daily dose is 30 mL of the syrup (providing 180 mg ambroxol and 6 mg levosalbutamol) in divided doses, or as prescribed by your doctor. Do not exceed this without medical advice.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
No known interaction
No significant interaction reported.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of amrox-ls syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take the medicine with food or milk to reduce stomach upset. If nausea persists, consult your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult your doctor if the headache is severe or persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you feel normal. Lie down if needed.
Tremor (shaky hands) (Common (5-10%))
This usually decreases with continued use. If it bothers you, inform your doctor.
Increased heart rate (Common (5-10%))
Monitor your pulse. If it feels very fast or irregular, contact your doctor.

🚨 Serious Side Effects

Severe palpitations or chest pain (Rare (<0.1%))
Seek immediate medical attention if you experience chest pain, severe palpitations, or difficulty breathing.
Allergic reaction (rash, swelling, difficulty breathing) (Rare (<0.1%))
Stop the medicine and get emergency help immediately if you notice swelling of the face, lips, or throat, or severe rash.
Severe skin reactions (Stevens-Johnson syndrome) (Very rare (<0.01%))
Seek immediate medical care if you develop painful skin rash, blisters, or peeling skin.
Hypokalemia (low potassium) (Rare (<0.1%))
Report muscle weakness, cramps, or irregular heartbeat to your doctor promptly.

⚠️ Rare Side Effects

Paradoxical bronchospasm
If breathing becomes worse after taking this medicine, stop it and seek emergency care.
Hyperglycemia
Monitor blood sugar if you are diabetic. Report persistent high readings to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Propranolol Major
MAOIs Major
Furosemide Moderate
Prednisolone Moderate
Digoxin Moderate
Amoxicillin Minor

🚨 Major Interactions

  • Non-selective beta-blockers (e.g., propranolol)
  • Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants

⚡ Moderate Interactions

  • Diuretics (e.g., furosemide, thiazides)
  • Corticosteroids
  • Digoxin

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and low blood pressure when taken with this medicine. It is advisable to avoid alcohol while using this product.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to ambroxol, levosalbutamol, or any component of the syrup","Severe cardiovascular disease including severe arrhythmias","Severe hepatic or renal impairment without medical supervision","Use in children below the age recommended by the prescribing doctor"]

⚠️ Warnings & Precautions

["This medicine should be used with caution in patients with heart disease, high blood pressure, or irregular heartbeat.","Patients with diabetes may experience increased blood sugar levels; monitor regularly.","Use with caution in patients with hyperthyroidism.","Avoid use in patients with a history of seizures unless prescribed.","Do not exceed the recommended dose; high doses may cause severe side effects.","If symptoms do not improve within a few days or worsen, consult your doctor.","Keep out of reach of children.","Do not use this medicine for a dry cough without mucus, as it may not be effective."]

🤱 Lactation Safety

Ambroxol is excreted in breast milk. Levosalbutamol may also pass into breast milk. It is not known whether this combination is safe during breastfeeding. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose of this medicine may cause severe tachycardia, palpitations, tremor, nausea, and low blood pressure. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Do not induce vomiting unless instructed by a healthcare professional.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase the dose or take it more often than directed. Shake the bottle well before each use and measure the dose with the measuring cup or spoon provided. This medicine is for oral use only. Avoid taking it at the same time as other cough syrups or bronchodilators without consulting your doctor. If you have heart disease, high blood pressure, diabetes, thyroid problems, or liver or kidney disease, tell your doctor before starting this medicine. Do not drive or operate heavy machinery if you feel dizzy or shaky after taking it. Keep this medicine out of the reach of children. Store it at room temperature, away from direct sunlight and moisture. Do not use it after the expiry date printed on the pack. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Do not share this medicine with anyone else, even if they have similar symptoms.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more prone to side effects such as tachycardia, tremor, and dizziness. Use with caution and monitor heart rate and blood pressure. Dose adjustment may be needed based on renal and hepatic function.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. The safety of this combination in pregnancy is not well established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

If you have recently undergone surgery, inform your surgeon and anesthesiologist that you are taking this medicine. Levosalbutamol can affect heart rate and blood pressure during surgery. Your doctor may advise temporary discontinuation.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may cause dry mouth and increase the risk of dental problems. Maintain good oral hygiene and stay hydrated.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke.
🥗
Use a humidifier at home to keep airways moist.
😴
Drink plenty of warm fluids to help loosen mucus.
💧
Practice deep breathing exercises as advised by your doctor.
🧘
Get adequate rest to support recovery.
🌞
Avoid known allergens and pollutants.

🏋️ Exercise Considerations

Avoid strenuous exercise while you are experiencing acute breathing difficulty. Once symptoms improve, gradually resume light activities. If exercise triggers wheezing, use your rescue inhaler as prescribed and consult your doctor.

🥗 Diet Recommendations

Stay well hydrated with water and warm fluids.
Include fruits and vegetables rich in vitamin C and antioxidants.
Avoid cold drinks and ice cream if they trigger cough.
Limit processed foods and excess salt.
Consume honey with warm water to soothe the throat, if not diabetic.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, tremor, or increased heart rate, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to inform your employer if your work involves safety-sensitive tasks.

🛑 When to Stop This Medicine

Stop this medicine and consult your doctor if your symptoms worsen, if you experience severe side effects, or if you have completed the prescribed course. Do not stop abruptly if you have been on it for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine should be under medical supervision. Prolonged use of levosalbutamol may lead to tolerance, reduced effectiveness, and increased risk of side effects such as tremors and palpitations. Ambroxol is generally well tolerated for short-term use. Regular monitoring of heart rate, blood pressure, and potassium levels may be needed. Do not use this medicine for longer than prescribed without consulting your doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and soothe airways.

Evidence: Well-established
Chest physiotherapy

Techniques to help clear secretions from the lungs.

Evidence: Well-established
Inhaled bronchodilators

May be preferred for rapid relief of bronchospasm.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are due for a vaccine, inform your doctor that you are taking this medicine. Annual influenza vaccination is recommended for patients with chronic respiratory diseases.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription or a letter from your doctor, especially for international travel. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust dosing times gradually to match your new schedule, but do not double up on doses. Check customs regulations for carrying prescription medicines in your destination country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with COPD and chronic productive cough
He was prescribed this medicine twice daily. After three days, he noticed that his cough became more productive and breathing felt easier. He experienced mild hand tremor initially, which reduced after a week. He was advised to take it with food to avoid stomach upset.
💡 Lesson: Consistent use as prescribed and taking with food improves tolerability. Mild tremors often diminish with continued use.
👤 A 32-year-old woman with acute bronchitis and wheezing
She started this medicine after a respiratory infection. Within two days, her wheezing decreased and she could cough out mucus more easily. She reported feeling a bit dizzy after the first dose, so she avoided driving for a few hours. She completed the prescribed course and recovered well.
💡 Lesson: Dizziness can occur initially; avoid driving until you know how the medicine affects you. Complete the full course as prescribed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The bronchodilator effect usually starts within 15-30 minutes, while the mucolytic effect may take a few hours. You may notice easier breathing and looser cough within a day.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is this medicine safe for children?

A: Pediatric dosing is not established from available information. Consult a pediatrician for appropriate use in children.

Q: Can I take this medicine if I am pregnant?

A: The safety of this medicine in pregnancy is not well established. Consult your doctor before using it if you are pregnant or planning pregnancy.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my heart?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe for my child?
  • Can I take it with antibiotics?

🔄 Substitutes for amrox-ls syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken for any type of cough.
    Fact: It is specifically for productive cough with bronchospasm. It is not effective for dry cough or cough due to allergies.
  • Myth: More syrup means faster relief.
    Fact: Taking more than the prescribed dose can cause serious side effects like rapid heartbeat and tremors. Always follow the doctor's advice.
  • Myth: It is safe to take with other over-the-counter cough syrups.
    Fact: Combining with other cough medicines can lead to overlapping ingredients and increased risk of side effects. Always consult a doctor or pharmacist.

🔄 Alternative Options

Generic Alternatives

  • Ambroxol + Levosalbutamol syrup (various manufacturers)

Brand Alternatives

  • Amrox-LS Syrup (Leeford Healthcare Ltd)

📊 Comparison with Similar Medicines

[{"medicine":"Ambroxol + Levosalbutamol","composition":"Ambroxol 30 mg + Levosalbutamol 1 mg per 5 mL","uses":"Productive cough with bronchospasm","notes":"This medicine"},{"medicine":"Ambroxol + Salbutamol","composition":"Ambroxol 30 mg + Salbutamol 2 mg per 5 mL","uses":"Productive cough with bronchospasm","notes":"Contains racemic salbutamol; may have more side effects."},{"medicine":"Ambroxol + Guaifenesin","composition":"Ambroxol 30 mg + Guaifenesin 50 mg per 5 mL","uses":"Productive cough","notes":"No bronchodilator; not for bronchospasm."}]

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