Lansi Kit: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Seizures or confusion
If experiencing severe symptoms, call emergency services immediately.
What is Pylomox 500 mg/750 mg/15 mg Kit used for?
This medicine is a prescription combination of tinidazole, amoxycillin, and lansoprazole used to treat certain gastrointestinal infections, including H. pylori, giardiasis, and amoebiasis. It works by killing bacteria and protozoa while reducing stomach acid. It must be taken exactly as prescribed, and alcohol must be avoided.
- Generic Name: Tinidazole (500mg) + Amoxycillin (750mg) + Lansoprazole (15mg)
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Pylomox 500 mg/750 mg/15 mg Kit के बारे में (Hindi Summary)
उपयोग: यह दवा टिनिडाजोल, अमोक्सिसिलिन और लैंसोप्राजोल का संयोजन है, जिसका उपयोग पेट के कुछ संक्रमणों जैसे एच. पाइलोरी, जियार्डिया और अमीबiasis के इलाज के लिए किया जाता है। यह कीटाणुओं और परजीवियों को मारती है और पेट के एसिड को कम करती है। इसे डॉक्टर के निर्देशानुसार ही लें और शराब का सेवन बिल्कुल न करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, मुँह में धातु जैसा स्वाद, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, रक्त विकार, यकृत की सूजन और दौरे पड़ सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न छोड़ें और कोर्स पूरा करें। भोजन के साथ लें। शराब का सेवन बिल्कुल न करें। यकृत या गुर्दे की बीमारी, रक्त विकार, गर्भावस्था या स्तनपान के बारे में डॉक्टर को बताएं। दवा को बच्चों से दूर रखें।
💊 Pylomox 500 mg/750 mg/15 mg Kit Uses & Benefits
- [{"condition":"Helicobacter pylori infection","description":"Used as part of combination therapy to eradicate H.
- pylori in patients with peptic ulcer disease or chronic gastritis.","evidence":"Well-established"},{"condition":"Giardiasis","description":"Effective against Giardia lamblia, a protozoan that causes diarrhea and malabsorption.","evidence":"Well-established"},{"condition":"Amoebiasis","description":"Treats intestinal and hepatic amoebiasis caused by Entamoeba histolytica.","evidence":"Well-established"},{"condition":"Bacterial gastroenteritis","description":"Covers susceptible anaerobic bacteria and some aerobic bacteria in mixed gastrointestinal infections.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Bacterial vaginosis","description":"Tinidazole component may be used off-label for bacterial vaginosis, but the combination is not standard.","evidence":"Limited"},{"condition":"Trichomoniasis","description":"Tinidazole is effective, but the combination with amoxycillin and lansoprazole is not typically used for this indication.","evidence":"Limited"}]
Primary treatment for: Helicobacter pylori infection
Also treats: Giardiasis, Amoebiasis, Bacterial gastroenteritis
📋 Drug Information
| Generic Name(s) | Tinidazole (500mg) + Amoxycillin (750mg) + Lansoprazole (15mg) |
| Brand Name | Pylomox 500 mg/750 mg/15 mg Kit |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Protect from light and moisture. Keep in the original packaging. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. Guidelines for H. pylori eradication vary by region. Consult local guidelines. |
| ICMR Guideline | Not established from the available information. ICMR guidelines for H. pylori management may recommend combination therapy. Consult a healthcare provider. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines three agents with distinct mechanisms. Tinidazole is a nitroimidazole that enters susceptible microorganisms and generates reactive oxygen species that damage DNA, leading to cell death. Amoxycillin is a beta-lactam antibiotic that binds to penicillin-binding proteins, inhibiting bacterial cell wall synthesis and causing bacterial lysis. Lansoprazole is a proton pump inhibitor that irreversibly blocks the hydrogen-potassium ATPase enzyme in gastric parietal cells, reducing gastric acid secretion. The combination targets both the infection and the acidic environment, enhancing efficacy against H. pylori and other pathogens.
Mechanism Steps
💡 How to Take Pylomox 500 mg/750 mg/15 mg Kit
Strength: Each kit contains tinidazole 500 mg, amoxycillin 750 mg, and lansoprazole 15 mg as immediate-release tablets.
Dosage Information
| Adult Dosage | The usual adult dose is one kit taken orally twice daily, typically for 7 to 14 days, depending on the indication. For H. pylori eradication, it is often combined with other antibiotics and a proton pump inhibitor. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose adjustment due to reduced renal and hepatic function. Use with caution and monitor for side effects. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, dose adjustment may be necessary. For creatinine clearance less than 30 mL/min, consider reducing the dose or extending the dosing interval. Consult a nephrologist or clinical pharmacist. |
| Hepatic Impairment | In patients with hepatic impairment, dose reduction may be required, especially for tinidazole and lansoprazole. Monitor liver function closely. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose is not established from available information. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Pylomox 500 mg/750 mg/15 mg Kit
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Alcohol | Major | |
| Methotrexate | Major | |
| Oral contraceptives | Moderate | |
| Allopurinol | Moderate | |
| Probenecid | Moderate | |
| Ketoconazole | Moderate | |
| Atazanavir | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Alcohol
- Methotrexate
- Oral contraceptives
- Allopurinol
⚡ Moderate Interactions
- Probenecid
- Ketoconazole
- Atazanavir
- Digoxin
🍷 Alcohol Interaction
Alcohol must be strictly avoided during treatment with this medicine and for at least 72 hours after the last dose. Tinidazole can cause a disulfiram-like reaction characterized by flushing, severe nausea, vomiting, headache, and rapid heartbeat. This reaction can be dangerous and requires immediate medical attention if it occurs.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to tinidazole, amoxycillin, lansoprazole, or other nitroimidazoles or penicillins","First trimester of pregnancy","Severe liver disease","Severe kidney disease (requires dose adjustment)","Blood dyscrasias or history of blood disorders","Neurological disorders with seizure history","Use of disulfiram within the past two weeks"]
⚠️ Warnings & Precautions
["Avoid alcohol during and for 72 hours after treatment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Complete the full course as prescribed to prevent resistance.","Inform your doctor if you have liver or kidney disease, blood disorders, or are pregnant or breastfeeding.","May reduce effectiveness of oral contraceptives; use backup contraception.","Monitor for signs of superinfection (e.g., oral thrush, vaginal yeast infection).","Use with caution in elderly patients due to increased risk of side effects."]
🤱 Lactation Safety
Tinidazole and amoxycillin are excreted in breast milk. Lansoprazole may also pass into breast milk. Breastfeeding is not recommended while taking this medicine. If treatment is essential, consult your doctor to discuss options and possibly pump and discard milk during therapy.
💊 Overdose Management
Overdose may cause nausea, vomiting, abdominal pain, dizziness, and seizures. There is no specific antidote. Treatment is supportive and symptomatic. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and provide anticonvulsants if seizures occur. Contact a poison control center or emergency department immediately.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Swallow the tablets whole with a full glass of water. Take with food to reduce stomach upset. Avoid alcohol completely during treatment and for at least 72 hours after the last dose. Inform your doctor if you have liver or kidney problems, blood disorders, or are pregnant or breastfeeding. Do not share this medicine with others. Keep out of reach of children. Store in a cool, dry place away from direct sunlight. If you miss a dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to side effects such as dizziness, confusion, and blood disorders. Dose adjustment may be needed based on renal and hepatic function. Monitor closely.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the first trimester. If you are planning pregnancy, consult your doctor to discuss alternative treatments. Use effective contraception during treatment and for at least 7 days after.
🏥 Post-Surgery Considerations
Inform your surgeon if you are taking this medicine before surgery. It may interact with anesthetics and increase bleeding risk. Your doctor may advise stopping it temporarily.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may increase bleeding risk during dental procedures. Your dentist may recommend postponing non-urgent procedures until you complete the course.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but if you experience dizziness or fatigue, avoid strenuous activities. Listen to your body and rest when needed.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery until you know how it affects you. Take it with food to minimize stomach upset. Most people can continue their normal daily activities with minor adjustments.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Complete the full prescribed course even if you feel better. If you experience severe side effects, contact your doctor immediately; they may advise you to stop or adjust the dose.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless specifically prescribed. Prolonged use may lead to bacterial resistance, superinfections, and rare blood or liver disorders. Regular monitoring of liver and kidney function may be required if extended therapy is necessary. Always consult your doctor before prolonging treatment.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help restore gut flora during and after antibiotic treatment.
Evidence: ModerateAvoiding irritants like alcohol and spicy foods can complement treatment.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, antibiotics may reduce the efficacy of live bacterial vaccines like typhoid vaccine. Consult your doctor for timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, adjust dosing times gradually to maintain even intervals. Check local customs regulations for carrying prescription medicines. Always carry enough for your entire trip and a few extra days in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 2-3 days, but it is important to complete the full course as prescribed, usually 7-14 days.
A: Inform your doctor about all medicines you take, especially blood thinners, methotrexate, and oral contraceptives, as interactions may occur.
A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for Pylomox 500 mg/750 mg/15 mg Kit
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once symptoms improve.
Fact: You must complete the full course to prevent recurrence and resistance. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol can cause a severe disulfiram-like reaction and must be avoided. - Myth: This medicine is a general antibiotic for any stomach infection.
Fact: It is specific for certain infections and should only be used as prescribed.
🔄 Alternative Options
Generic Alternatives
- Tinidazole 500 mg + Amoxycillin 750 mg + Lansoprazole 15 mg kit
Brand Alternatives
- Lansi Kit