amarin m2 tablet er
What is amarin m2 tablet er used for?
Amaryl M 1mg Tablet PR (Glimepiride + Metformin) is used to treat ANTI DIABETIC. It contains Glimepiride (2mg) + Metformin (500mg), which Glimepiride: Stimulates insulin release from pancreatic beta cells; Metformin: D. Always consult your doctor before use. Take as prescribed.
- Generic Name: Glimepiride + Metformin
- Manufacturer: Ernst Pharmacia
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ amarin m2 tablet er Uses & Benefits
Type 2 diabetes mellitus when diet and exercise alone are inadequate
Off-label uses: Polycystic ovary syndrome (metformin component)
๐ Drug Information
| Generic Name(s) | Glimepiride + Metformin |
| Brand Name | Amaryl M 1mg Tablet PR |
| Manufacturer | Ernst Pharmacia |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI DIABETIC |
| Action Class | Sulfonylurea + Biguanide |
| Route of Administration | Oral |
| Storage | Store at 25ยฐC (77ยฐF); excursions permitted to 15-30ยฐC (59-86ยฐF); protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Glimepiride: Stimulates insulin release from pancreatic beta cells; Metformin: Decreases hepatic glucose production, increases insulin sensitivity
Mechanism Steps
๐ก How to Take amarin m2 tablet er
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of amarin m2 tablet er
โ Common Side Effects
- Hypoglycemia
- Nausea
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
๐จ Serious Side Effects
- Lactic acidosis
- Severe hypoglycemia
- Hepatic injury
- Pancreatitis
โ ๏ธ Rare Side Effects
- Megaloblastic anemia
- Photosensitivity
- Disulfiram-like reaction
- Cholestatic jaundice
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Insulin | Major | Increased risk of hypoglycemia |
| Miconazole | Major | Enhanced hypoglycemic effect |
| Alcohol | Major | Increased risk of lactic acidosis and hypoglycemia |
| ACE inhibitors | Moderate | Enhanced hypoglycemic effect |
| Beta-blockers | Moderate | Mask hypoglycemia symptoms |
| Corticosteroids | Moderate | Hyperglycemia |
| Diuretics | Moderate | Hyperglycemia |
| NSAIDs | Moderate | Enhanced hypoglycemic effect |
| Cimetidine | Minor | Increased metformin levels |
| Nifedipine | Minor | Increased metformin absorption |
๐จ Major Interactions
- Insulin
- Other sulfonylureas
- Miconazole
- Phenylbutazone
- Alcohol
โก Moderate Interactions
- ACE inhibitors
- Beta-blockers
- Clarithromycin
- Corticosteroids
- Diuretics
- NSAIDs
โน๏ธ Minor Interactions
- Cimetidine
- Ranitidine
- Nifedipine
๐ฝ๏ธ Food Interactions
Food delays absorption of glimepiride; metformin absorption reduced by food
๐ท Alcohol Interaction
Increased risk of hypoglycemia and lactic acidosis
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Type 1 diabetes, diabetic ketoacidosis, severe renal impairment (eGFR <30), hepatic impairment, hypersensitivity, acute conditions with risk of hypoxia
๐ Monitoring Parameters
Blood glucose, HbA1c, renal function (serum creatinine, eGFR), hepatic function, signs of lactic acidosis
๐คฑ Lactation Safety
Contraindicated; glimepiride excreted in milk, metformin excreted in milk
๐ Overdose Management
Monitor blood glucose; treat hypoglycemia with oral glucose or IV dextrose; for metformin overdose, consider hemodialysis
โฐ Missed Dose
Take as soon as remembered unless near next dose; do not double dose
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
Effective and reliable. Worked as expected.
Good quality medicine. Satisfied with the outcome.
Found this to be a helpful product. Good results.
Found this to be a helpful product. Good results.
Helpful and effective medicine as per my experience. Always consult a doctor.