Cyra-LS Tablet SR: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe abdominal pain or cramping
- Chest pain, palpitations, or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes (jaundice)
- Decreased urine output or swelling in legs
- Uncontrollable muscle movements or tremors
- High fever with muscle rigidity and confusion
If experiencing severe symptoms, call emergency services immediately.
What is actorab-ls capsule sr used for?
This medicine is a combination of Levosulpiride and Rabeprazole used to treat acid reflux, gastritis, and functional dyspepsia. It works by reducing stomach acid and improving stomach emptying. It is taken orally once daily before breakfast, usually for short-term treatment.
- Generic Name: Levosulpiride + Rabeprazole
- Manufacturer: Fitwel Pharmaceuticals Private Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 actorab-ls capsule sr के बारे में (Hindi Summary)
उपयोग: यह दवा लेवोसल्पिराइड और रैबेप्राजोल का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, गैस्ट्र्रिटिस और अपच के इलाज के लिए किया जाता है। यह पेट में एसिड को कम करती है और पेट को खाली करने में मदद करती है। इसे सुबह नाश्ते से पहले खाली पेट लेना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चक्कर आना, नींद आना, मतली, दस्त, पेट दर्द और मुँह सूखना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको दिल की धड़कन में अनियमितता, मांसपेशियों में अकड़न, या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे चबाएं या तोड़ें नहीं, पूरा निगल लें। इसे सुबह नाश्ते से पहले खाली पेट लें। इस दवा के साथ शराब न लें। यदि आप गर्भवती हैं या स्तनपान करा रही हैं तो डॉक्टर को बताएं। दवा बंद करने से पहले डॉक्टर से सलाह लें।
💊 actorab-ls capsule sr Uses & Benefits
[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Reduces acid reflux and heartburn by suppressing gastric acid secretion and improving gastric emptying.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"Helps relieve symptoms like bloating, early satiety, and upper abdominal discomfort by enhancing gastric motility and reducing acid.","evidence":"Moderate"},{"condition":"Gastritis","description":"Provides relief from inflammation of the stomach lining by reducing acid production and promoting gastric emptying.","evidence":"Moderate"},{"condition":"Peptic ulcer disease","description":"Used as part of combination therapy to heal ulcers and relieve symptoms by acid suppression and prokinetic action.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Diabetic gastroparesis","description":"Sometimes prescribed off-label to improve gastric emptying in patients with diabetes.","evidence":"Limited"},{"condition":"Nausea and vomiting of various causes","description":"Levosulpiride component may help reduce nausea and vomiting, but this is not a primary approved indication.","evidence":"Limited"}]
Primary treatment for: Gastroesophageal reflux disease (GERD)
Also treats: Functional dyspepsia, Gastritis, Peptic ulcer disease
📋 Drug Information
| Generic Name(s) | Levosulpiride + Rabeprazole |
| Brand Name | Acera-L Capsule SR |
| Manufacturer | Fitwel Pharmaceuticals Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Prokinetic agent + Proton pump inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Levosulpiride is a selective dopamine D2 receptor antagonist that enhances gastric motility and accelerates gastric emptying. Rabeprazole is a proton pump inhibitor that irreversibly blocks the hydrogen-potassium ATPase enzyme in gastric parietal cells, thereby reducing both basal and stimulated acid secretion. Together, they provide symptomatic relief in conditions where both acid suppression and improved gastric motility are beneficial.
Mechanism Steps
💡 How to Take actorab-ls capsule sr
Strength: Tablet containing Levosulpiride 75 mg and Rabeprazole 20 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet of Levosulpiride 75 mg and Rabeprazole 20 mg taken orally once daily before breakfast on an empty stomach. However, the dose and duration must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of Levosulpiride, especially extrapyramidal symptoms and drowsiness. Dose adjustment may be necessary. Consult a doctor for appropriate dosing. |
| Renal Impairment | Levosulpiride is primarily excreted by the kidneys. Dose reduction may be required in patients with renal impairment. Rabeprazole does not require dose adjustment in mild to moderate renal impairment. Consult a doctor for individualized dosing. |
| Hepatic Impairment | No specific dose adjustment is established for Rabeprazole in hepatic impairment, but caution is advised in severe liver disease. Levosulpiride should be used with caution in patients with hepatic impairment. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet containing Levosulpiride 75 mg and Rabeprazole 20 mg. Do not exceed this dose unless directed by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of actorab-ls capsule sr
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ketoconazole | Major | |
| Atazanavir | Major | |
| Methotrexate | Major | |
| Diazepam | Moderate | |
| Phenytoin | Moderate | |
| Levodopa | Moderate | |
| Anticholinergics | Moderate | |
| Antacids | Minor | |
| Sucralfate | Minor |
🚨 Major Interactions
- Warfarin
- Ketoconazole, Itraconazole
- Atazanavir, Nelfinavir
- Methotrexate
⚡ Moderate Interactions
- Diazepam
- Phenytoin
- Levodopa
- Anticholinergics
🍷 Alcohol Interaction
Alcohol may increase drowsiness and dizziness caused by Levosulpiride. It may also worsen stomach irritation. Avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Levosulpiride, Rabeprazole, or any component of the formulation","Suspected or confirmed gastrointestinal obstruction, perforation, or bleeding","Prolactin-dependent tumors (e.g., pituitary adenoma, breast cancer)","Severe renal impairment (creatinine clearance < 20 mL/min)","Epilepsy or history of seizures","Concurrent use with levodopa","Pregnancy and breastfeeding unless clearly needed"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol while taking this medicine.","Use with caution in elderly patients due to increased risk of extrapyramidal symptoms.","May increase risk of bone fractures with long-term use.","May cause low magnesium levels with prolonged use; monitor if taking diuretics.","May increase risk of Clostridium difficile-associated diarrhea.","Do not use for more than 8 weeks without medical advice.","Inform your doctor if you have heart rhythm problems or are taking other medications that affect heart rhythm."]
🤱 Lactation Safety
It is not known whether Levosulpiride or Rabeprazole are excreted in human breast milk. Consult your doctor before breastfeeding while taking this medicine.
💊 Overdose Management
Overdose may cause severe drowsiness, extrapyramidal symptoms, or cardiac arrhythmias. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if overdose is recent. Monitor vital signs and ECG.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with water. It is best taken before breakfast on an empty stomach, but follow your doctor's specific instructions. Avoid alcohol while taking this medicine as it may increase drowsiness and stomach irritation. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Do not stop taking this medicine abruptly without consulting your doctor. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of extrapyramidal symptoms, drowsiness, and fractures with long-term use. Dose adjustment may be necessary. Regular monitoring of renal function and magnesium levels is advised.
🤰 Pregnancy Planning (TTC)
Consult your doctor before planning pregnancy while taking this medicine. The safety of this combination during pregnancy is not well established. Your doctor may consider alternative treatments.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may interact with anesthetic agents and affect gastric motility. Your doctor may advise you to stop it temporarily before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may cause dry mouth, which can affect dental health. Maintain good oral hygiene and stay hydrated.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid vigorous exercise immediately after taking this medicine, especially if you experience drowsiness or dizziness. Moderate exercise like walking is generally safe. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness and dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause fatigue, so plan your work schedule accordingly. Consult your doctor if side effects interfere with your daily activities.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms resolve, your doctor may advise you to stop gradually. Abrupt discontinuation may cause rebound acid hypersecretion.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of bone fractures, low magnesium levels, vitamin B12 deficiency, and Clostridium difficile-associated diarrhea. Prolonged use of Levosulpiride may cause tardive dyskinesia. Regular monitoring of magnesium, vitamin B12, and renal function is advised. Use the lowest effective dose for the shortest duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Dietary changes, weight loss, and elevating the head of the bed can help manage GERD symptoms.
Evidence: Well-establishedOmeprazole, Pantoprazole, or Esomeprazole may be used as alternatives.
Evidence: Well-establishedRanitidine or Famotidine may be used for milder symptoms.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, long-term use of proton pump inhibitors may slightly reduce the immune response to certain vaccines. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Rabeprazole starts reducing acid within 1 hour, and Levosulpiride improves gastric motility within 30-60 minutes. Symptom relief may take a few days.
A: It is best taken on an empty stomach, preferably 30-60 minutes before breakfast. Food may delay absorption.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Do not stop taking this medicine without consulting your doctor. Abrupt discontinuation may cause rebound acid hypersecretion.
A: Consult your doctor before taking this medicine during pregnancy. The safety profile is not well established.
🤔 Common Patient Concerns
🔄 Substitutes for actorab-ls capsule sr
View AllAlternative brands with exact same active ingredient:
-
lavirabe ls 75mg/20mg capsuleLavish Biotech ₹17.81 86.4% CHEAPER
-
rabeyog tabletVotary Laboratories I Ltd ₹22.50 82.9% CHEAPER
-
ropraz ls 75mg/20mg tabletSun Pharmaceutical Industries Ltd ₹36.56 72.1% CHEAPER
-
davazole l 75mg/20mg capsule srDavaindia Generic Pharmacy ₹40.00 69.5% CHEAPER
-
raberide-ls capsule srZeelab Pharmacy Pvt Ltd ₹45.00 65.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken indefinitely for acid reflux.
Fact: This medicine is usually prescribed for short-term use. Long-term use should be under medical supervision due to potential side effects. - Myth: It is safe to take this medicine without a prescription.
Fact: This is a prescription medicine. It should only be taken under a doctor's supervision. - Myth: This medicine can be taken with alcohol without any issues.
Fact: Alcohol may increase drowsiness and dizziness. Avoid alcohol while taking this medicine.
🔄 Alternative Options
Generic Alternatives
- Levosulpiride 75 mg + Rabeprazole 20 mg tablet
Brand Alternatives
- Cyra-LS Tablet SR