abcixirel 10mg injection

4.7 (14 reviews)

Abciximab (10mg)

🏭 Reliance Life Sciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is abcixirel 10mg injection used for?

Abcixirel (Abciximab) is used to treat BLOOD RELATED. It contains Abciximab (10mg), which Abciximab is a monoclonal antibody fragment that binds to the glycoprotein IIb/I. Always consult your doctor before use. Take as prescribed.

Generic Name: Abciximab
Manufacturer: Reliance Life Sciences
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 abcixirel 10mg injection Uses & Benefits

Prevention of ischemic complications in patients undergoing percutaneous coronary intervention (PCI), unstable angina not responding to conventional therapy.

Off-label uses: Acute ST-elevation myocardial infarction (STEMI) as adjunct to thrombolysis, thrombotic thrombocytopenic purpura (TTP).

📋 Drug Information

Generic Name(s)	Abciximab
Brand Name	Abcixirel
Manufacturer	Reliance Life Sciences
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	BLOOD RELATED
Action Class	Glycoprotein IIb/IIIa inhibitors
Route of Administration	Intravenous bolus followed by continuous infusion.
Storage	Store at 2-8°C (36-46°F); do not freeze. Protect from light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntravenous administration results in rapid and complete bioavailability.

DistributionDistributes primarily in plasma; volume of distribution approximately 0.1 L/kg.

Protein BindingApproximately 98% bound to plasma proteins.

MetabolismMetabolized by proteolytic cleavage into small peptides and amino acids.

Half-LifeInitial half-life <10 minutes; second phase half-life about 30 minutes; terminal half-life approxima

ExcretionExcreted primarily via urine as metabolites and small peptides.

Bioavailability100% (intravenous).

Onset of ActionWithin minutes of administration.

Peak Plasma TimeImmediately after infusion.

Duration of ActionPlatelet function recovery begins within 12-24 hours; effects persist for up to 48 hours.

How It Works

Abciximab is a monoclonal antibody fragment that binds to the glycoprotein IIb/IIIa receptor on platelets, inhibiting platelet aggregation.

Mechanism Steps

1Abciximab binds to the glycoprotein IIb/IIIa receptor on activated platelets.

2Blocks binding of fibrinogen and von Willebrand factor to the receptor.

3Prevents platelet cross-linking and aggregation.

💡 How to Take abcixirel 10mg injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of abcixirel 10mg injection

✅ Common Side Effects

Bleeding (minor)
Hypotension
Nausea
Vomiting
Back pain

🚨 Serious Side Effects

Major bleeding (intracranial, retroperitoneal, gastrointestinal)
Thrombocytopenia
Anaphylaxis
Severe hypotension

⚠️ Rare Side Effects

Pulmonary hemorrhage
Acute profound thrombocytopenia
Hemolytic uremic syndrome

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Heparin	Major	Increased bleeding risk
Aspirin	Major	Increased bleeding risk
Clopidogrel	Major	Increased bleeding risk
NSAIDs	Moderate	Increased bleeding risk
SSRIs	Moderate	Increased bleeding risk

🚨 Major Interactions

Warfarin
Heparin
Low molecular weight heparins
Other antiplatelet agents (e.g., aspirin, clopidogrel)
Thrombolytics

⚡ Moderate Interactions

NSAIDs
Selective serotonin reuptake inhibitors (SSRIs)
Anticoagulants (e.g., dabigatran, rivaroxaban)

ℹ️ Minor Interactions

Herbal supplements with antiplatelet effects (e.g., ginkgo, garlic)

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

May increase bleeding risk; avoid excessive alcohol consumption.

🛡️ Safety & Warnings

🚫 Contraindications

Active internal bleeding, recent major surgery or trauma, history of intracranial hemorrhage, severe hypertension, thrombocytopenia, use of dextran before or during treatment.

📊 Monitoring Parameters

Platelet count, bleeding time, signs of bleeding, hemoglobin/hematocrit.

🤱 Lactation Safety

Unknown if excreted in breast milk; caution advised.

💊 Overdose Management

Monitor for bleeding; discontinue infusion; consider platelet transfusion if severe bleeding occurs.

⏰ Missed Dose

Not applicable; administered in controlled clinical setting.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for abcixirel 10mg injection

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Alternative brands with exact same active ingredient (Abciximab (10mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Regular Customer Jul 10, 2026