Alburel 5% Solution for Infusion: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or shortness of breath
- Swelling of the face, lips, or throat
- Chest pain or tightness
- Sudden drop in blood pressure or fainting
- Severe rash or hives
- Decreased urine output
- Swelling in the legs or abdomen
- Confusion or dizziness
If experiencing severe symptoms, call emergency services immediately.
What is alburel 5% solution for infusion used for?
This medicine is a 5% human albumin solution given intravenously to restore blood volume and treat low albumin levels. It is used in hospitals for conditions like severe blood loss, liver disease, and burns.
- Generic Name: Albumin (5%)
- Manufacturer: Reliance Life Sciences
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 alburel 5% solution for infusion के बारे में (Hindi Summary)
उपयोग: यह दवा मानव एल्ब्यूमिन का 5% घोल है जो नस के माध्यम से दिया जाता है। इसका उपयोग रक्त की मात्रा बढ़ाने और शरीर में एल्ब्यूमिन की कमी को पूरा करने के लिए किया जाता है। यह गंभीर रक्तस्राव, जलन, लीवर की बीमारी और पेट से अधिक तरल निकालने के बाद होने वाली समस्याओं में दी जाती है। यह दवा केवल अस्पताल में डॉक्टर या नर्स द्वारा ही दी जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में हल्का बुखार, ठंड लगना, खुजली, चकत्ते और घबराहट शामिल हैं। गंभीर दुष्प्रभावों में सांस लेने में कठिनाई, रक्तचाप में अचानक गिरावट, चेहरे या गले में सूजन और पैरों में सूजन हो सकती है। अगर ऐसे लक्षण दिखें तो तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल अस्पताल में डॉक्टर की निगरानी में ही दी जानी चाहिए। अगर आपको एल्ब्यूमिन या किसी ब्लड प्रोडक्ट से एलर्जी है, दिल की बीमारी है, किडनी की समस्या है या खून बहने की बीमारी है, तो डॉक्टर को पहले बताएं। इंजेक्शन के दौरान ब्लड प्रेशर, नाड़ी और सांस की जांच होती रहनी चाहिए। घर पर इस दवा का इस्तेमाल न करें।
💊 alburel 5% solution for infusion Uses & Benefits
[{"condition":"Hypovolemia due to blood loss or severe dehydration","description":"This medicine restores circulating blood volume when a patient has lost a large amount of blood or fluids, helping to stabilize blood pressure and organ perfusion.","evidence":"Well-established"},{"condition":"Hypoalbuminemia in liver disease","description":"Used to raise low albumin levels in patients with advanced liver disease, especially when accompanied by inflammation" class="semantic-link" title="Medicines for swelling">swelling or fluid in the abdomen.","evidence":"Well-established"},{"condition":"Large-volume paracentesis","description":"Given after removal of a large amount of fluid from the abdomen to prevent a sudden drop in blood pressure and to maintain circulation.","evidence":"Well-established"},{"condition":"Burns","description":"May be used in the first 24 hours after a major burn to replace lost plasma volume and maintain circulation.","evidence":"Established in specific protocols"},{"condition":"Cardiopulmonary bypass priming","description":"Sometimes added to the priming solution of the heart-lung machine during cardiac surgery to maintain volume and oncotic pressure.","evidence":"Established in specific protocols"},{"condition":"Nephrotic syndrome","description":"Occasionally used to treat severe swelling in patients with nephrotic syndrome who have very low albumin levels.","evidence":"Limited"}]
Off-label uses: [{"condition":"Ovarian hyperstimulation syndrome","description":"Sometimes used to treat fluid shifts and low blood volume in women with this condition after fertility treatment.","evidence":"Limited"},{"condition":"Spontaneous bacterial peritonitis","description":"May be used alongside antibiotics to reduce the risk of kidney failure in patients with infected abdominal fluid.","evidence":"Emerging"}]
Primary treatment for: Hypovolemia
Also treats: Hypoalbuminemia, Liver cirrhosis, Nephrotic syndrome, Burns, Large-volume paracentesis
📋 Drug Information
| Generic Name(s) | Albumin (5%) |
| Brand Name | alburel 5% solution for infusion |
| Manufacturer | Reliance Life Sciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | Colloids (Plasma substitutes) |
| Route of Administration | Parenteral (intravenous infusion) |
| Storage | Store this medicine at room temperature between 20°C and 25°C (68°F to 77°F). Do not freeze. Keep it in the original container and protect it from light. Do not use if the solution is cloudy or has particles. |
| Shelf Life | The shelf life is typically 24 to 36 months from the date of manufacture, depending on the specific product. Always check the expiry date on the label before use. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by increasing the colloid osmotic pressure of blood. Albumin is a large protein that does not easily cross capillary membranes, so it stays in the bloodstream and draws fluid from the surrounding tissues into the blood vessels. This expands the circulating blood volume, improves blood pressure, and helps maintain blood flow to vital organs. Albumin also binds and transports many substances, including hormones, fatty acids, and drugs, and it acts as an antioxidant and a buffer.
Mechanism Steps
💡 How to Take alburel 5% solution for infusion
Strength: 5% solution for infusion (50 mg/mL)
Dosage Information
| Adult Dosage | The dose of this medicine is determined by the treating doctor based on the patient's condition, weight, and laboratory results. For hypovolemia, a common starting dose is 250 to 500 mL of the 5% solution, given as a slow intravenous infusion. The rate is adjusted according to blood pressure, heart rate, and urine output. For hypoalbuminemia, the dose depends on the albumin level and the presence of swelling. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to fluid shifts and should receive this medicine with caution. The dose is usually individualized based on cardiovascular and kidney function. Monitoring for signs of fluid overload is especially important. |
| Renal Impairment | Patients with kidney disease may need careful monitoring of fluid balance and kidney function. The dose should be adjusted by the clinician based on the patient's condition. No specific dose adjustment is established from available information. |
| Hepatic Impairment | Patients with liver disease may have altered albumin metabolism. The dose should be individualized by the clinician based on the severity of liver disease and albumin levels. No specific dose adjustment is established from available information. |
| Maximum Daily Dose | The maximum daily dose is not fixed and depends on the patient's clinical condition. It must be determined by a qualified clinician. In general, the dose should not exceed what is needed to achieve the desired clinical effect. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of alburel 5% solution for infusion
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Furosemide | Major | |
| ACE inhibitors | Major | |
| Warfarin | Moderate | |
| Antihypertensives | Moderate | |
| Penicillins | Minor |
🚨 Major Interactions
- Loop diuretics (e.g., furosemide)
- ACE inhibitors
⚡ Moderate Interactions
- Antihypertensive drugs
- Warfarin
🍷 Alcohol Interaction
Alcohol can worsen dehydration and fluid imbalances, which may counteract the benefits of this medicine. Patients receiving this medicine should avoid alcohol unless specifically permitted by their doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to human albumin or any component of the product","Severe heart failure or pulmonary edema","Severe anemia due to iron deficiency","Conditions where increased blood volume could be harmful, such as uncontrolled hypertension"]
⚠️ Warnings & Precautions
["This medicine must be given only by a healthcare professional.","Infusion should be started slowly and the patient monitored for reactions.","Use with caution in patients with heart failure, kidney disease, or bleeding disorders.","Do not use if the solution is cloudy or contains particles.","Do not mix with other medicines or blood products in the same line unless approved.","Pregnant and breastfeeding women should receive this medicine only if clearly needed.","Elderly patients may be more sensitive to fluid shifts and should be monitored closely."]
🤱 Lactation Safety
It is not known whether human albumin passes into breast milk. Because it is a natural protein, any amount in breast milk is likely to be broken down in the infant's gut. However, breastfeeding mothers should receive this medicine only if clearly needed and under medical supervision.
💊 Overdose Management
Overdose with this medicine can cause fluid overload, leading to high blood pressure, swelling, and pulmonary edema. Treatment is supportive and may include stopping the infusion, giving diuretics, and providing oxygen. There is no specific antidote. Patients should be monitored closely until symptoms resolve.
⏰ Missed Dose
This medicine is given in a hospital or clinic setting, so a missed dose is unlikely. If a scheduled dose is missed, the healthcare team will decide when to give the next dose based on the patient's condition. Do not attempt to self-administer this medicine.
Additional Safety Advice
This medicine must only be given by a trained healthcare professional in a hospital or clinic where vital signs can be monitored. Before the infusion starts, tell your doctor if you have ever had an allergic reaction to albumin or any blood product, if you have heart failure, kidney disease, or a bleeding disorder, and if you are pregnant or breastfeeding. The infusion rate should be started slowly and increased only if you tolerate it well. Your doctor will check your blood pressure, heart rate, breathing, and urine output during and after the infusion. Do not attempt to use this medicine at home or without medical supervision. If you notice swelling, shortness of breath, chest pain, or a rash during the infusion, alert the nurse or doctor immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to fluid shifts and may develop heart failure or pulmonary edema. The dose should be adjusted carefully, and vital signs should be monitored closely during and after the infusion.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, discuss with your doctor before receiving this medicine. It should be used during pregnancy only if clearly needed. There is no evidence that it affects fertility.
🏥 Post-Surgery Considerations
This medicine may be used during or after surgery to maintain blood volume. After surgery, monitor for signs of fluid overload and follow your surgeon's instructions for activity and diet.
🦷 Dental Procedures
This medicine is not typically used in dental procedures. If you have received it recently, inform your dentist. There are no specific precautions for dental work, but maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise immediately after receiving this medicine. Light activity is fine once you feel well, but check with your doctor before starting any new exercise routine, especially if you have heart or kidney problems.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital or clinic, so it may require a short stay. After the infusion, you may feel tired for a few hours. Avoid driving or operating machinery until you feel fully alert. Most people can return to normal activities the next day, but follow your doctor's advice.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. It is given by a healthcare professional who will decide when to stop based on your condition. If you experience side effects, the infusion may be stopped or slowed. Always consult your doctor before making any changes.
📅 Long-Term Use Effects
Long-term use of this medicine is not common because it is usually given for short periods in acute settings. Repeated infusions may be needed in chronic conditions like liver disease, but this should be guided by a specialist. Long-term monitoring includes regular blood tests for albumin levels, kidney function, and fluid balance. There is no evidence that long-term use causes harm beyond the risks of fluid overload and allergic reactions.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Saline or Ringer's lactate can be used for volume expansion in some cases.
Evidence: Well-establishedDextran or hydroxyethyl starch may be used as alternatives, but they have different risk profiles.
Evidence: Established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your doctor that you have received this medicine. Live vaccines should be given with caution in patients with severe liver disease or immune suppression.
📦 Storage Guide
✅ DO
Store at room temperature (20-25°C)
❌ DON'T
Do not freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from light
❌ DON'T
Do not use if the solution is cloudy or has particles
✈️ Traveling with This Medicine
This medicine is given in a hospital or clinic, so travel advice is not applicable for self-administration. If you are traveling after receiving this medicine, carry a copy of your prescription and medical records. Keep the medicine in its original packaging if you need to transport it, and store it at room temperature. Check with your doctor before traveling, especially if you have heart or kidney problems.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The effect on blood volume begins within minutes of starting the infusion, but the full clinical response may take 15 to 30 minutes.
A: No, this medicine must be given by a healthcare professional in a hospital or clinic setting.
A: Common side effects include mild fever, chills, rash, itching, and flushing. These are usually mild and settle on their own.
A: It should be used during pregnancy only if clearly needed and under medical supervision.
🤔 Common Patient Concerns
🔄 Substitutes for alburel 5% solution for infusion
View AllAlternative brands with exact same active ingredient:
-
human albumin 5% infusionBaxter India Pvt Ltd ₹5,490.00 263% COSTLIER
-
albiomin 5% infusionPaviour Pharmaceuticals Pvt Ltd ₹6,668.00 340.9% COSTLIER
-
Plasmanate 5% InfusionBharat Serums & Vaccines Ltd ₹7,860.94 419.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Albumin is a nutritional supplement.
Fact: Albumin is not a nutritional supplement. It is used to restore blood volume and treat specific medical conditions. - Myth: Albumin can be taken orally.
Fact: Albumin must be given intravenously. It is not effective when taken by mouth because it is digested like any other protein. - Myth: Albumin is a blood transfusion.
Fact: Albumin is a plasma protein product, not whole blood. It does not contain red blood cells or clotting factors.
🔄 Alternative Options
Generic Alternatives
- Human albumin 5% solution for infusion (generic)
Brand Alternatives
- Alburel 5% solution for infusion
- Albumin 5% solution for infusion (various manufacturers)