adalirel 20mg injection

4.7 (10 reviews)

Adalimumab (20mg)

🏭 Reliance Life Sciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is adalirel 20mg injection used for?

Adalipca 40mg Injection (Adalimumab) is used to treat ANTI NEOPLASTICS. It contains Adalimumab (20mg), which Adalimumab is a recombinant human IgG1 monoclonal antibody that binds specifical. Always consult your doctor before use. Take as prescribed.

Generic Name: Adalimumab
Manufacturer: Reliance Life Sciences
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 adalirel 20mg injection Uses & Benefits

Rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, plaque psoriasis, hidradenitis suppurativa, uveitis.

Off-label uses: Behçet's disease, Sarcoidosis, Pyoderma gangrenosum, Graft-versus-host disease

📋 Drug Information

Generic Name(s)	Adalimumab
Brand Name	Adalipca 40mg Injection
Manufacturer	Reliance Life Sciences
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI NEOPLASTICS
Action Class	Disease Modifying Anti-Rheumatoid Drugs (DMARDs)- Biologics
Route of Administration	Subcutaneous injection.
Storage	Store at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionSubcutaneous administration results in slow absorption with peak serum concentrations reached approximately 5 days after a single dose.

DistributionDistributes into the vascular space and extravascular tissues; volume of distribution is about 4.7-6 L.

Protein BindingBinds to TNF-alpha; no specific protein binding data available.

MetabolismDegraded into small peptides and amino acids via proteolytic catabolism.

Half-LifeApproximately 10-20 days (mean 14 days).

ExcretionNot excreted renally; eliminated via reticuloendothelial system.

BioavailabilityApproximately 64% after subcutaneous injection.

Onset of ActionClinical response may be seen within 1-2 weeks.

Peak Plasma Time5 days (131 hours) after a single subcutaneous dose.

Duration of ActionSustained effect due to long half-life; dosing every 2 weeks.

How It Works

Adalimumab is a recombinant human IgG1 monoclonal antibody that binds specifically to human tumor necrosis factor-alpha (TNF-alpha) and neutralizes its biological activity by blocking its interaction with p55 and p75 cell surface TNF receptors.

Mechanism Steps

1Adalimumab binds to soluble and membrane-bound TNF-alpha with high affinity.

2Neutralizes TNF-alpha activity by preventing its interaction with TNFR1 and TNFR2 receptors.

3Reduces TNF-alpha-mediated pro-inflammatory cytokine production (e.g., IL-1, IL-6).

💡 How to Take adalirel 20mg injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of adalirel 20mg injection

✅ Common Side Effects

Injection site reactions (erythema, itching, pain)
Upper respiratory infections
Headache
Nausea
Rash

🚨 Serious Side Effects

Serious infections (tuberculosis, invasive fungal infections)
Malignancies (lymphoma)
Demyelinating disorders
Heart failure exacerbation
Lupus-like syndrome

⚠️ Rare Side Effects

Aplastic anemia
Stevens-Johnson syndrome
Hepatitis B reactivation
Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Abatacept	Major	Increased risk of serious infections
Anakinra	Major	Increased risk of serious infections and neutropenia
Live vaccines	Major	Risk of disseminated infection
Tocilizumab	Major	Increased immunosuppression and infection risk
Cyclosporine	Moderate	Reduced efficacy of cyclosporine
Warfarin	Moderate	Altered anticoagulant effect
Theophylline	Moderate	Increased theophylline levels
ACE inhibitors	Minor	Possible decreased efficacy of ACE inhibitors
Beta-blockers	Minor	Possible decreased efficacy of beta-blockers

🚨 Major Interactions

Abatacept
Anakinra
Live vaccines
Tocilizumab

⚡ Moderate Interactions

Cyclosporine
Warfarin
Theophylline

ℹ️ Minor Interactions

ACE inhibitors
Beta-blockers

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

No specific interaction; caution with liver function.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to adalimumab or any component; active infections including tuberculosis; moderate to severe heart failure (NYHA class III/IV).

📊 Monitoring Parameters

Monitor for signs of infection, tuberculosis screening before and during therapy, CBC, liver function tests, and injection site reactions.

🤱 Lactation Safety

Excreted in breast milk; caution advised.

💊 Overdose Management

No specific antidote; monitor for adverse effects and provide supportive care.

⏰ Missed Dose

If a dose is missed, administer as soon as remembered; then resume regular schedule. Do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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⭐ User Reviews

Happy Patient Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.