anfoe 10000iu injection allopathy (Recombinant Human Erythropoietin Alfa (10000IU)) - Uses in Hindi, Side Effects, Substitutes & Price in India
anfoe 10000iu injection allopathy (Recombinant Human Erythropoietin Alfa (10000IU)) - Uses in Hindi, Side Effects, Substitutes & Price in India manufactured by La Renon Healthcare Pvt Ltd. Contains Recombinant Human Erythropoietin Alfa (10000IU).

anfoe 10000iu injection - Uses, Price, Side Effects & Substitutes

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Recombinant Human Erythropoietin Alfa (10000IU) (Click to see all medicines with same salt)
🏭 La Renon Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Jun 21, 2026
Medically Reviewed
By SaathiMed Expert Medical Panel

What is anfoe 10000iu injection used for?

Anfoe 10000IU Injection (Recombinant Human Erythropoietin Alfa) is used to treat Anemia in chronic kidney disease. It contains Recombinant Human Erythropoietin Alfa (10000IU), which Stimulates erythropoiesis by binding to erythropoietin receptors on erythroid pr. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Recombinant Human Erythropoietin Alfa
  • Manufacturer: La Renon Healthcare Pvt Ltd
  • Medicine Form: Allopathy
  • Pregnancy Category: A

🇮🇳 anfoe 10000iu injection के बारे में संक्षिप्त जानकारी (Hindi Summary)

anfoe 10000iu injection का उपयोग मुख्य रूप से blood related और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Recombinant Human Erythropoietin Alfa (10000IU) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।

मुख्य फायदे (Key Benefits): Anfoe 10000IU Injection is a medicine that helps your bone marrow to produce more red blood cells. It is used to treat a type of anemia caused by kidn... Read more below.

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

📋 Drug Information

Generic Name(s)Recombinant Human Erythropoietin Alfa
Brand NameAnfoe 10000IU Injection
ManufacturerLa Renon Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action ClassErythropoiesis-stimulating agent (ESA)
Route of AdministrationSubcutaneous or intravenous injection
StorageStore at 2-8°C (refrigerate). Do not freeze. Protect from light.
Shelf LifeAs per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionSubcutaneous: slow absorption; Intravenous: immediate
DistributionPrimarily in plasma; small volume of distribution
Protein BindingApproximately 50%
MetabolismPartially metabolized in liver
Half-LifeSubcutaneous: ~24 hours; Intravenous: ~4-13 hours
ExcretionPrimarily renal (small amount unchanged)
BioavailabilitySubcutaneous: ~20-30%
Onset of ActionSeveral days to weeks
Peak Plasma TimeSubcutaneous: 12-24 hours; Intravenous: immediate
Duration of ActionSeveral days

Pharmacodynamics

Mechanism of ActionStimulates erythropoiesis by binding to erythropoietin receptors on erythroid progenitor cells, promoting their proliferation and differentiation into red blood cells.
Target ReceptorErythropoietin receptor (EPO-R)
Pharmacodynamic EffectsIncreases hemoglobin levels, red blood cell count, and reticulocyte count; improves oxygen delivery to tissues.

💡 How and when to take anfoe 10000iu injection?

Follow your doctor's prescription exactly.

  • ✅ Take exactly as prescribed by your doctor.
  • ✅ Do not exceed the recommended dose
  • ✅ Complete the full course of medication
  • ✅ Store at 2-8°C (refrigerate). Do not freeze. Protect from light.

⚙️ How anfoe 10000iu injection Works

Stimulates erythropoiesis by binding to erythropoietin receptors on erythroid progenitor cells, promoting their proliferation and differentiation into red blood cells.

1 Binds to erythropoietin receptor (EPO-R) on erythroid progenitor cells in bone marrow.
⬇️
2 Activates JAK2/STAT5 signaling pathway.
⬇️
3 Promotes survival, proliferation, and differentiation of erythroid progenitors.
⬇️
4 Increases red blood cell production and release into circulation.
⬇️
5 Elevates hemoglobin and hematocrit levels.

💊 anfoe 10000iu injection Uses in Hindi (Ke Fayde), Benefits & Indications

Anemia in chronic kidney disease, anemia in cancer patients on chemotherapy, reduction of allogeneic blood transfusion in surgery, anemia in HIV patients treated with zidovudine.

Off-label uses: Anemia of prematurity, anemia in inflammatory bowel disease, myelodysplastic syndromes (selected cases).

⚠️ What are the side effects of anfoe 10000iu injection?

✅ Common Side Effects

  • Hypertension
  • Headache
  • Arthralgia
  • Nausea
  • Diarrhea
  • Injection site pain

🚨 Serious Side Effects

  • Thromboembolic events (e.g., stroke, MI)
  • Pure red cell aplasia (PRCA)
  • Hypertensive encephalopathy
  • Seizures

⚠️ Rare Side Effects

  • Allergic reactions
  • Hyperkalemia
  • Porhyria
  • Tumor progression (theoretical)

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug Severity Effect
Androgens Major Increased erythropoiesis and risk of polycythemia
ACE inhibitors Major Reduced erythropoietin efficacy
Immunosuppressants Major Decreased erythropoietic response
Heparin Moderate Increased risk of thrombosis
Iron supplements Moderate Enhanced erythropoiesis when iron deficient
Antihypertensives Moderate May require dose adjustment due to blood pressure changes
Corticosteroids Minor Possible additive effect on erythropoiesis
Estrogens Minor Possible additive effect on erythropoiesis

🚨 Major Interactions

  • Androgens
  • ACE inhibitors
  • Immunosuppressants

⚡ Moderate Interactions

  • Heparin
  • Iron supplements
  • Antihypertensives

ℹ️ Minor Interactions

  • Corticosteroids
  • Estrogens

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

🚫 Contraindications

Uncontrolled hypertension, known hypersensitivity to mammalian cell-derived products or albumin, pure red cell aplasia (PRCA) with prior erythropoietin therapy.

📊 Monitoring Parameters

Hemoglobin, hematocrit, blood pressure, iron stores (ferritin, transferrin saturation), reticulocyte count.

🤱 Lactation Safety

Not known if excreted in breast milk; caution advised

💊 Overdose Management

Monitor for hypertension and polycythemia; phlebotomy may be needed if hemoglobin exceeds target.

⏰ Missed Dose

Administer as soon as remembered; if close to next dose, skip missed dose and resume regular schedule. Do not double dose.

🛑 Myths vs. Facts about anfoe 10000iu injection

  • Myth: Generic substitutes of anfoe 10000iu injection are less effective.
    Fact: Approved generic medicines contain the exact same active ingredients (Recombinant Human Erythropoietin Alfa (10000IU)) and are just as safe and effective as the branded version.
  • Myth: Taking a double dose will cure my symptoms faster.
    Fact: Taking more than the prescribed dose of anfoe 10000iu injection can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage.
  • Myth: This medicine is 100% safe for everyone.
    Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.

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